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This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2014]
[中文简述(自动翻译):]  这个基因编码位于细胞间紧密连接的胞质膜表面的蛋白质。所编码的蛋白质可在细胞 - 细胞结参与信号转导。这个基因的选择性剪接的结果在多个转录变体。 [由RefSeq的,2014年7月提供]
TJP1基因(以及对应的蛋白质)的细胞分布位置:
TJP1基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Brain Diseases | 0.08 | 1 | 0 | RGD |
| Brain Ischemia | 0.08 | 1 | 0 | RGD |
| Cholestasis | 0.08 | 1 | 0 | RGD |
| Diabetes Mellitus, Experimental | 0.08 | 1 | 0 | RGD |
| Peptic Esophagitis | 0.08 | 1 | 0 | RGD |
| Pain | 0.08 | 1 | 0 | RGD |
| Reperfusion Injury | 0.08 | 2 | 0 | RGD |
| Subarachnoid Hemorrhage | 0.08 | 1 | 0 | RGD |
| Uveitis | 0.08 | 1 | 0 | RGD |
| Necrotizing Enterocolitis | 0.08 | 1 | 0 | RGD |
| Arthritis, Experimental | 0.08 | 1 | 0 | RGD |
| Neoplasm Metastasis | 0.0054487 | 2 | 0 | LHGDN |
| melanoma | 0.003267234 | 2 | 0 | BeFree_LHGDN |
| Mammary Neoplasms | 0.002995792 | 2 | 0 | BeFree_LHGDN |
| Asthma | 0.00272435 | 1 | 0 | LHGDN |
| Colorectal Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
| DiGeorge Syndrome | 0.00272435 | 1 | 0 | LHGDN |
| Heart failure | 0.00272435 | 1 | 0 | LHGDN |
| Hepatitis C | 0.00272435 | 1 | 0 | LHGDN |
| Thyroid Neoplasm | 0.00272435 | 1 | 0 | LHGDN |
| Liver carcinoma | 0.00272435 | 1 | 0 | LHGDN |
| Celiac Disease | 0.000814326 | 3 | 0 | BeFree |
| Non-Small Cell Lung Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Diabetes Mellitus, Insulin-Dependent | 0.000542884 | 2 | 0 | BeFree |
| Aneurysm | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of breast | 0.000271442 | 1 | 0 | BeFree |
| Small cell carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
| Adrenoleukodystrophy | 0.000271442 | 1 | 0 | BeFree |
| Angelman Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
| Secondary malignant neoplasm of pancreas | 0.000271442 | 1 | 0 | BeFree |
| Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
| Oestrogen deficiency | 0.000271442 | 1 | 0 | BeFree |
| Cerebral Aneurysm | 0.000271442 | 1 | 0 | BeFree |
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