更多...
收起
The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  由该基因编码的蛋白质属于Tec家族含有普列克底物蛋白同源结构域非受体蛋白酪氨酸激酶。 Tec家族激酶参与细胞因子受体,淋巴细胞表面抗原,异源G蛋白偶联受体和整联分子的细胞内信号传导的机制。他们也是在免疫功能的调节关键球员。 Tec的激酶是T细胞信号传导的一个组成部分,并在T细胞活化有显着作用。该基因可以与骨髓增生异常综合征有关。 [由RefSeq的,2008年7月提供]
TEC基因(以及对应的蛋白质)的细胞分布位置:
TEC基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
HIV Infections | 0.002367032 | 1 | 0 | GAD |
Inflammatory Bowel Diseases | 0.002367032 | 1 | 1 | GAD |
Lymphedema | 0.002367032 | 1 | 0 | GAD |
Narcolepsy | 0.002367032 | 1 | 0 | GAD |
Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
Extraskeletal Myxoid Chondrosarcoma | 0.002171535 | 8 | 0 | BeFree |
Extraskeletal Myxoid Chondrosarcoma | 0.002171535 | 8 | 0 | BeFree |
Chondrosarcoma | 0.000814326 | 3 | 0 | BeFree |
Chondrosarcoma | 0.000814326 | 3 | 0 | BeFree |
Anemia | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of breast | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of breast | 0.000542884 | 2 | 0 | BeFree |
Renal Cell Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Renal Cell Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Myasthenia Gravis | 0.000542884 | 2 | 0 | BeFree |
Myasthenia Gravis | 0.000542884 | 2 | 0 | BeFree |
Transient erythroblastopenia of childhood | 0.000542884 | 2 | 0 | BeFree |
Breast Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Breast Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Crohn Disease | 0.000271442 | 1 | 0 | BeFree |
Crohn Disease | 0.000271442 | 1 | 0 | BeFree |
Neuroblastoma | 0.000271442 | 1 | 0 | BeFree |
Neuroblastoma | 0.000271442 | 1 | 0 | BeFree |
Preleukemia | 0.000271442 | 1 | 0 | BeFree |
Preleukemia | 0.000271442 | 1 | 0 | BeFree |
Thymoma | 0.000271442 | 1 | 0 | BeFree |
Thymoma | 0.000271442 | 1 | 0 | BeFree |
Central neuroblastoma | 0.000271442 | 1 | 0 | BeFree |
Central neuroblastoma | 0.000271442 | 1 | 0 | BeFree |
Anemia, Diamond-Blackfan | 0.000271442 | 1 | 0 | BeFree |
Epithelioma | 0.000271442 | 1 | 0 | BeFree |
Epithelioma | 0.000271442 | 1 | 0 | BeFree |
Liver carcinoma | 0.000271442 | 1 | 0 | BeFree |
Liver carcinoma | 0.000271442 | 1 | 0 | BeFree |
MYELODYSPLASTIC SYNDROME | 0.000271442 | 1 | 0 | BeFree |
MYELODYSPLASTIC SYNDROME | 0.000271442 | 1 | 0 | BeFree |
忘记密码? 点击找回密码.
扫一扫右方二维码,关注微信订阅号,实时查看信息,关注医学生物学动态。