TBP(TATA box binding protein)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

6q27
基因染色体位置图

基因简述

基因简述

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010]

[中文简述(自动翻译):]  由RNA聚合酶II转录起始需要70多个多肽的活动。它协调这些活动的蛋白质是转录因子的IID（TFIID），其结合到核心启动子正确定位聚合酶，作为支架的转录复合物的其余部分的组件，并作为调节信号的信道。 TFIID是由TATA结合蛋白（TBP）和一组被称为TBP相关因子或TAFS进化保守的蛋白质的。 TAFS可能参与基础转录，作为共激活因子，功能的启动子识别或修改一般转录因子（基转移酶），以方便复杂的组装和转录起始。该基因编码TBP，塔塔结合蛋白。 TBP的一个显着特点是在N端谷氨酰胺的长字符串。该蛋白质的该区域调制C末端的DNA结合活性，和DNA结合调制影响的转录复合物形成和转录起始速率。 CAG数重复编码多聚谷氨酰胺道通常是32-39，并且重复的次数的扩大增加了聚谷氨酰胺字符串的长度，并与脊髓小脑性共济失调17，归类为聚谷氨酰胺疾病神经变性疾病相关联。已发现该基因编码不同亚型的两个转录变异体。 [由RefSeq的，2010年2月提供]

OMIM数据库中对TBP基因的介绍     Wikipedia数据库中对TBP基因的介绍

基因序列

基因序列

TBP基因的碱基序列：[NCBI]

基因突变

基因突变

TBP基因的碱基突变：           显示全部snp
rs12717       rs2179373       rs2206286       rs4710839       rs5881875       rs6918474       rs10946279       rs12210583       rs12210836       rs17550878       rs17860796       rs17860797       rs17860799       rs41270527       rs57158953       rs57668737       rs58175196       rs58758881       rs59555240       rs60257797       rs60714788       rs60913811       rs61249181       rs61508644       rs111838486       rs112126254       rs114299458       rs116503181       rs138433416       rs140014483       rs140706179       rs140787251       rs141759441       rs141832711       rs144132255       rs144829611       rs145421663      
rs148515679       rs150121150       rs150645256       rs150942579       rs182576054       rs185292465       rs186944530       rs187328526       rs192051369       rs193078532       rs193143767       rs199930873       rs200449804       rs367927347       rs368386910       rs369453212       rs369947650       rs370607592       rs371461026       rs372026766       rs372370346       rs373030081       rs374764687       rs375360014       rs376415142       rs376425056       rs377457915       rs397767584       rs527710575       rs528162423       rs528212781       rs528593397       rs529529687       rs529874034       rs530269472       rs532285929       rs533476852       rs534645579       rs534721875       rs536263187       rs536904691       rs537075955       rs537247109       rs538445166       rs538479725       rs538935986       rs541011303       rs541392491       rs541977710       rs542237344       rs543434273       rs544815412       rs544881262       rs545999137       rs546541153       rs547194211       rs548024801       rs548508995       rs548790182       rs549089962       rs549380479       rs549751039       rs551943707       rs552203630       rs553302456       rs554214267       rs554242772       rs554800209       rs554886392       rs558620444       rs558657278       rs559418806       rs559419350       rs559597769       rs561432357       rs562440242       rs563164635       rs563642041       rs564851920       rs566267179       rs569958402       rs570420558       rs570558968       rs571149976       rs571188016       rs575557038       rs576096031       rs576133254       rs576875977       rs576909175       rs578245441       rs745583589       rs745844112       rs749244705       rs749310290       rs750917791       rs751331565       rs751936241       rs752789293       rs754026068       rs755261693       rs755859794       rs756529459       rs759741619       rs761244885       rs761557599       rs762213623       rs762393571       rs762625742       rs763670527       rs765433248       rs766734584       rs766974261       rs769579603       rs771557813       rs773959715       rs774818021       rs775071049       rs776629233       rs777801687       rs779662101       rs780014344       rs780210566       rs781075523       rs1042327       rs2072916       rs2076318       rs2235506       rs3800235       rs3823298       rs6456230       rs6456231       rs6911104       rs6916281       rs6927768       rs6928833       rs6929565       rs6937840       rs6940817       rs7746898       rs7760641       rs7765023       rs7771229       rs9348342       rs9348343       rs9348344       rs9348345       rs9366157       rs9366247       rs9460226       rs9460227       rs10632592       rs10691201       rs10946281       rs11962869       rs12193323       rs12194821       rs12195143       rs12200657       rs12202577       rs12203550       rs12527072       rs12664331       rs13207114       rs16901474       rs17860787       rs17860788       rs17860789       rs34485638       rs35269766       rs55736770       rs55985680       rs56241301       rs58221238       rs59966437       rs60225324       rs61130006       rs61486120       rs61619130       rs62430309       rs62430342       rs66520324       rs71010672       rs71010674       rs71576554       rs71688178       rs71815788       rs73256666       rs73256671       rs73256702       rs73258604       rs73258619       rs73793712       rs74416461       rs74497423       rs74723330       rs74830282       rs74927771       rs75187732       rs75901181       rs76100602       rs76856885       rs76926312       rs76979237       rs77693808       rs78045471       rs79076153       rs80046763       rs80210328       rs111229737       rs111438200       rs111938894       rs112036086       rs112083427       rs112100346       rs112141011       rs112163523       rs112575731       rs112748399       rs112928724       rs113125482       rs113202486       rs113287612       rs113423337       rs113440919       rs113692167       rs114191101       rs114304353       rs116225559       rs116308908       rs116712539       rs117097771       rs117391470       rs117681043       rs117721558       rs118056400       rs118066307       rs138026963       rs138359819       rs138394219       rs138627335       rs138915574       rs139122769       rs139154045       rs139166099       rs139491247       rs139744657       rs139955007       rs139969412       rs140075049       rs140089853       rs140116135       rs140229172       rs140236128       rs140262695       rs140361815       rs141003941       rs141558119       rs141778159       rs141870984       rs142041644       rs142139918       rs142221089       rs142355912       rs142479007       rs142540266       rs142914329       rs143116974       rs143153971       rs143618719       rs143655307       rs143969868       rs144068492       rs144199880       rs144312230       rs145394458       rs145633894       rs145927188       rs146011133       rs146082443       rs146398449       rs146449494       rs146460433       rs146652853       rs147028433       rs147491896       rs147582772       rs147637810       rs147902959       rs147919924       rs148074761       rs148273967       rs148609911       rs148760675       rs148799605       rs148876634       rs149041588       rs149069562       rs149397770       rs149441883       rs149568324       rs149619633       rs149667326       rs150312586       rs150374643       rs150696457       rs180773583       rs180881409       rs180918772       rs180958944       rs181054286       rs181430564       rs181654101       rs181737672       rs181795476       rs182171785       rs182420138       rs182876624       rs182962933       rs182994771       rs183638228       rs183645270       rs183723709       rs183849030       rs184218376       rs184592175       rs184616262       rs184660047       rs184720719       rs184745751       rs184916522       rs185477204       rs186022103       rs186278983       rs186391157       rs186508667       rs187092680       rs187412646       rs187456918       rs187648676       rs187808978       rs187959507       rs187968965       rs188221261       rs188895316       rs189052701       rs189123194       rs189577196       rs189715661       rs189718037       rs189829478       rs189882302       rs189983740       rs190204422       rs190355799       rs190384340       rs190765415       rs191076110       rs191207771       rs191379930       rs191927060       rs192247236       rs192254913       rs192690901       rs192716998       rs193156024       rs199525433       rs199616061       rs199911417       rs200023019       rs200216849       rs200427038       rs200431432       rs200496051       rs200670704       rs201189241       rs201290934       rs201300919       rs201430534       rs201578035       rs201584904       rs201700623       rs201952922       rs368103631       rs368651499       rs369222150       rs369252493       rs369276648       rs369728326       rs369883539       rs370692746       rs370881260       rs371615096       rs372258195       rs372737526       rs372970346       rs373205116       rs373332416       rs373596362       rs374303067       rs374621399       rs374823044       rs375063272       rs375256062       rs375575792       rs376507961       rs376585300       rs376588487       rs377127291       rs377236869       rs377297576       rs377394208       rs377439624       rs377494502       rs527463800       rs527537028       rs527670724       rs528070949       rs528123317       rs528511098       rs528549501       rs528667887       rs528745469       rs528846268       rs528875120       rs528914074       rs529321297       rs529358510       rs529360613       rs529474653       rs529501807       rs529728048       rs529744556       rs530209082       rs530243445       rs530424493       rs530593423       rs531012112       rs531401952       rs531473369       rs531588128       rs532109426       rs532191450       rs532333178       rs532625449       rs532757298       rs533000312       rs533202978       rs533679967       rs533725054       rs533755539       rs533796802       rs534008998       rs534356030       rs534997942       rs535034794       rs535068107       rs535348707       rs535594917       rs535670070       rs535707819       rs535847069       rs535884884       rs535965555       rs536230188       rs536248624       rs536425776       rs537032010       rs537043160       rs537067180       rs537471016       rs537508862       rs537611678       rs537645994       rs537682918       rs537946725       rs538275525       rs538277933       rs538315042       rs538497281       rs538606927       rs538622343       rs538643561       rs538875721       rs539203619       rs539311920       rs539705418       rs539840378       rs539960752       rs540034815       rs540147659       rs540178324       rs540224697       rs540365310       rs540612190       rs540641224       rs540830773       rs540868558       rs541190587       rs541359952       rs541436122       rs542030081       rs542031948       rs542161105       rs542206881       rs542416667       rs542422611       rs542561352       rs542598429       rs542635230       rs543745942       rs543793219       rs544585467       rs544762083       rs544773517       rs544844480       rs544969804       rs545354870       rs545663602       rs545787907       rs546221473       rs546346843       rs546381838       rs546952577       rs547117388       rs547165906       rs547205286       rs547495461       rs547557978       rs547673051       rs547682833       rs548097837       rs548219868       rs548462601       rs548742362       rs548778535       rs549506775       rs549639184       rs550077330       rs550147735       rs550478786       rs550848111       rs550964384       rs551005124       rs551752313       rs551889211       rs552117611       rs552168844       rs552353890       rs552670775       rs552754507       rs553066251       rs553101127       rs553682200       rs553774936       rs553823136       rs553936079       rs554007267       rs554579584       rs554639895       rs554899642       rs555033574       rs555601239       rs555866968       rs555877708       rs556216132       rs556395221       rs556674517       rs556832961       rs556883783       rs556976292       rs557283814       rs557320476       rs557613293       rs557619238       rs557849728       rs558063408       rs558181790       rs558465908       rs558770381       rs558826157       rs558863660       rs559300214       rs559386285       rs559455163       rs559602680       rs559638619       rs559640554       rs560212747       rs560245615       rs560865740       rs560901959       rs561178517       rs561304917       rs561626945       rs562109830       rs562148364       rs562185300       rs562940300       rs562975303       rs563218037       rs563352089       rs563388884       rs563620389       rs563772034       rs564069390       rs564227494       rs564559767       rs564672437       rs564834945       rs565047333       rs565127661       rs565657951       rs565724370       rs565742331       rs565754175       rs565844130       rs565979522       rs566225355       rs566309984       rs566374180       rs566594141       rs566641139       rs566865193       rs567028337       rs567141835       rs567162863       rs567165066       rs567179762       rs567713263       rs567920953       rs567965200       rs567965440       rs568367361       rs568367398       rs568507471       rs568984983       rs569022090       rs569099105       rs569176806       rs569495490       rs569710951       rs569952731       rs570015853       rs570735880       rs570906454       rs570948371       rs570982971       rs571031260       rs571202670       rs571894931       rs571965859       rs572451001       rs572482452       rs572500880       rs572572464       rs572821370       rs573290799       rs573400054       rs573466763       rs573618262       rs573680381       rs574029608       rs574313609       rs574356279       rs574677234       rs574714675       rs574714728       rs574743433       rs575222163       rs575538362       rs575866011       rs575904154       rs576238873       rs577033379       rs577037078       rs577070091       rs577264316       rs577651390       rs577954050       rs578042365       rs745424208       rs745830790       rs746127880       rs746177895       rs746303115       rs746396810       rs746721960       rs746876501       rs746997126       rs747033709       rs747363929       rs747419428       rs747758413       rs747786221       rs747940424       rs748211378       rs748266569       rs748469320       rs748590964       rs748740885       rs749081341       rs749422951       rs749604546       rs749788903       rs749830313       rs749884185       rs749938009       rs750153878       rs750280284       rs750580709       rs750797320       rs750824039       rs751047986       rs751279107       rs751439588       rs751439710       rs751515739       rs751702127       rs751986065       rs752087383       rs752552729       rs752657767       rs752841089       rs752995266       rs753119768       rs753505824       rs753601035       rs753686356       rs753900483       rs754217817       rs754420055       rs754652346       rs754760599       rs754901264       rs755153007       rs755210619       rs755407976       rs755629023       rs755731466       rs756008941       rs756061944       rs756227958       rs756303791       rs756459088       rs756475719       rs756483712       rs756931059       rs756970637       rs756986278       rs757450205       rs757658844       rs757770542       rs757813852       rs758309293       rs758602293       rs758957983       rs759012154       rs759102124       rs759229912       rs759370933       rs759374115       rs759404487       rs759685453       rs759710446       rs760155887       rs760224751       rs761268467       rs761751666       rs761867883       rs762025441       rs762077353       rs762389131       rs762455360       rs762627715       rs762795778       rs762804204       rs762934477       rs763078270       rs763804938       rs763833755       rs764009292       rs764035011       rs764101448       rs764142412       rs764245588       rs764468384       rs764608771       rs764813677       rs764966099       rs765126059       rs765196791       rs765206064       rs765776627       rs765935074       rs766191843       rs766351185       rs766596848       rs767422449       rs767501232       rs767668285       rs767895067       rs768105201       rs768108642       rs768234723       rs768333442       rs768479093       rs768744129       rs768903671       rs769275781       rs769504560       rs769870393       rs770272859       rs770671659       rs770705419       rs770959789       rs771116530       rs771634403       rs771969944       rs772198875       rs772221948       rs772344160       rs772346620       rs772732214       rs772911295       rs773248432       rs773389193       rs773452147       rs773671685       rs774127646       rs774242068       rs774448149       rs774531109       rs774673727       rs774834014       rs774935855       rs775087307       rs775093030       rs775448208       rs775603111       rs775653922       rs776116052       rs776117522       rs776220323       rs776345097       rs776907521       rs776912164       rs777089714       rs777144535       rs777182875       rs777248773       rs777381416       rs777619049       rs777626558       rs778199326       rs778241571       rs778434821       rs778805694       rs778977394       rs779168063       rs779192906       rs779443911       rs779471026       rs779546062       rs779944203       rs779959339       rs780283741       rs780609393       rs780988715       rs781366910      

基因表达

基因表达

TBP基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AAGTGACATTATCAACGCGC
60
GAAACAGTGATGCTGGGTC
59
CTACTCTGCTGTGTTTCGC
59
GAAACAGTGATGCTGCCTG
60
AGCCAAGAGTGAAGAACAG
57
AAGTCCAAGAACTTAGCTGG
58
AGTGACATTATCAACGCGC
59
AGAAACAGTGATGCTGGGT
59
TACTCTGCTGTGTTTCGCA
60
GAAACAGTGATGCTGCCTG
60
AGCCAAGAGTGAAGAACAG
57
AAGTCCAAGAACTTAGCTGG
58
GCCAAGAGTGAAGAACAGTC
59
AAGTCCAAGAACTTAGCTGGA
59
GTATTAACAGGTGCTAAAGTCAGAG
60
TCTTCCTGAATCCCTTTAGAATAGG
60
GTTTCCTATAAGTTATGAGCCAGAG
59
TTTCTGCTCTGACTTTAGCAC
59
GCCAAGAGTGAAGAACAGTC
59
AGTCCAAGAACTTAGCTGGA
58

转录因子

转录因子

转录因子
影响类型
PubMed链接
APP
Unknown
8015372
BCL2
Repression
11313951
BDKRB1
Unknown
15705059
CCNB1
Unknown
17098936
CDKN1A
Unknown
17996705
CRP
Unknown
18684932
E2F1
Unknown
9400991
FOS
Activation
15767669
FUS
Repression
19841068
IGFBP4
Unknown
11058964

基因本体信息

TBP基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

TBP基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0003677
H0Y6D8(UniProtKB)
IEA
GO:0006352
H0Y6D8(UniProtKB)
IEA
GO:0000978
P20226(UniProtKB)
IEA
GO:0000979
P20226(UniProtKB)
IEA
GO:0001103
P20226(UniProtKB)
IEA
GO:0001939
P20226(UniProtKB)
IEA
GO:0001940
P20226(UniProtKB)
IEA
GO:0003700
P20226(UniProtKB)
IEA
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005515
P20226(UniProtKB)
IPI
GO:0005654
P20226(UniProtKB)
IDA
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005654
P20226(UniProtKB)
TAS
GO:0005669
P20226(UniProtKB)
IDA
GO:0005669
P20226(UniProtKB)
IDA
GO:0005672
P20226(UniProtKB)
IDA
GO:0005719
P20226(UniProtKB)
IDA
GO:0005737
P20226(UniProtKB)
IEA
GO:0006361
P20226(UniProtKB)
TAS
GO:0006361
P20226(UniProtKB)
TAS
GO:0006362
P20226(UniProtKB)
TAS
GO:0006363
P20226(UniProtKB)
TAS
GO:0006366
P20226(UniProtKB)
IDA
GO:0006366
P20226(UniProtKB)
IC
GO:0006366
P20226(UniProtKB)
TAS
GO:0006367
P20226(UniProtKB)
IC
GO:0006367
P20226(UniProtKB)
TAS
GO:0006367
P20226(UniProtKB)
TAS
GO:0006368
P20226(UniProtKB)
TAS
GO:0006383
P20226(UniProtKB)
IDA
GO:0007283
P20226(UniProtKB)
IEA
GO:0008134
P20226(UniProtKB)
IPI
GO:0008134
P20226(UniProtKB)
IPI
GO:0008134
P20226(UniProtKB)
IPI
GO:0008134
P20226(UniProtKB)
IPI
GO:0008134
P20226(UniProtKB)
IPI
GO:0008134
P20226(UniProtKB)
IPI
GO:0016032
P20226(UniProtKB)
IEA
GO:0019899
P20226(UniProtKB)
IPI
GO:0019899
P20226(UniProtKB)
IPI
GO:0042795
P20226(UniProtKB)
TAS
GO:0044212
P20226(UniProtKB)
IDA
GO:0044212
P20226(UniProtKB)
IDA
GO:0044212
P20226(UniProtKB)
IDA
GO:0045815
P20226(UniProtKB)
TAS
GO:0045893
P20226(UniProtKB)
IEA
GO:0070491
P20226(UniProtKB)
IPI
GO:1901796
P20226(UniProtKB)
TAS
GO:0003677
Q32MN6(UniProtKB)
IEA
GO:0005515
Q32MN6(UniProtKB)
IPI
GO:0005515
Q32MN6(UniProtKB)
IPI
GO:0005515
Q32MN6(UniProtKB)
IPI
GO:0006352
Q32MN6(UniProtKB)
IEA
GO:0003677
Q7Z6S4(UniProtKB)
IEA
GO:0005654
Q7Z6S4(UniProtKB)
IDA
GO:0006352
Q7Z6S4(UniProtKB)
IEA
GO:0003677
Q7Z6S5(UniProtKB)
IEA
GO:0005654
Q7Z6S5(UniProtKB)
IDA
GO:0006352
Q7Z6S5(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控TBP基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
SPINOCEREBELLAR ATAXIA 17 0.441357209 5 1 BeFree_CLINVAR_CTD_human_MGD_ORPHANET
PARKINSON DISEASE, LATE-ONSET 0.24 0 1 CLINVAR_CTD_human
Ataxia, Spinocerebellar 0.03403343 43 0 BeFree_GAD_LHGDN
Huntington Disease 0.013278246 9 0 BeFree_GAD_LHGDN
Parkinson Disease 0.013006804 7 0 BeFree_GAD_LHGDN
Ataxia 0.005352893 12 0 BeFree_GAD
Alzheimer's Disease 0.005091382 2 0 GAD_LHGDN
Cerebellar Ataxia 0.003724241 6 0 BeFree_GAD
Diabetes Mellitus, Insulin-Dependent 0.003181358 3 1 BeFree_GAD
Schizophrenia 0.003181358 3 0 BeFree_GAD
Neurodegenerative Disorders 0.002985861 11 0 BeFree
Malignant neoplasm of breast 0.002638474 2 0 BeFree_GAD
Dystonia, Primary 0.002638474 1 0 BeFree_GAD
Cardiac Arrest 0.002442977 9 0 BeFree
Myoclonic Cerebellar Dyssynergia 0.002367032 1 0 GAD
Restless Legs Syndrome 0.002367032 1 0 GAD
Genomic Instability 0.002367032 1 0 GAD
Dentatorubral-Pallidoluysian Atrophy 0.002171535 8 0 BeFree
Parkinsonian Disorders 0.001628651 6 0 BeFree
Chorea 0.000814326 3 0 BeFree
Presenile dementia 0.000814326 3 0 BeFree
Machado-Joseph Disease 0.000814326 3 0 BeFree
Neurologic Symptoms 0.000814326 3 0 BeFree
Progressive cerebellar ataxia 0.000814326 3 0 BeFree
Dementia 0.000814326 3 0 BeFree
Malignant neoplasm of urinary bladder 0.000542884 2 0 BeFree
Dystonia 0.000542884 2 0 BeFree
Liver neoplasms 0.000542884 2 0 BeFree
Seizures 0.000542884 2 0 BeFree
Hereditary spherocytosis 0.000542884 2 0 BeFree
Vitiligo 0.000542884 2 0 BeFree
Ataxic 0.000542884 2 0 BeFree
Pallidoluysian degeneration 0.000542884 2 0 BeFree
Dystonia Disorders 0.000542884 2 0 BeFree
Carcinoma of bladder 0.000542884 2 0 BeFree
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) 0.000542884 2 0 BeFree
Liver carcinoma 0.000542884 2 0 BeFree
SPHEROCYTOSIS, TYPE 1 (disorder) 0.000542884 2 0 BeFree
Adenocarcinoma 0.000271442 1 0 BeFree
Adenoma 0.000271442 1 0 BeFree
Ataxias, Hereditary 0.000271442 1 0 BeFree
Choriocarcinoma 0.000271442 1 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
Dystonia Musculorum Deformans 0.000271442 1 0 BeFree
Pulmonary Hypertension 0.000271442 1 0 BeFree
Inflammatory Bowel Diseases 0.000271442 1 0 BeFree
melanoma 0.000271442 1 0 BeFree
Mental Retardation 0.000271442 1 0 BeFree
Muscle Rigidity 0.000271442 1 0 BeFree
Myoclonus 0.000271442 1 0 BeFree
nervous system disorder 0.000271442 1 0 BeFree
Pulmonary Fibrosis 0.000271442 1 0 BeFree
Retinal Degeneration 0.000271442 1 0 BeFree
Systemic Scleroderma 0.000271442 1 0 BeFree
Shy-Drager Syndrome 0.000271442 1 0 BeFree
Embryonal Carcinoma 0.000271442 1 0 BeFree
Psychiatric symptom 0.000271442 1 0 BeFree
Gallbladder Carcinoma 0.000271442 1 0 BeFree
Cerebellar degeneration 0.000271442 1 0 BeFree
Sclerosis of the skin 0.000271442 1 0 BeFree
Autosomal dominant hereditary disorder 0.000271442 1 0 BeFree
Spastic syndrome 0.000271442 1 0 BeFree
New Variant Creutzfeldt-Jakob Disease 0.000271442 1 0 BeFree
Multiple System Atrophy 0.000271442 1 0 BeFree
Benign Hereditary Chorea 0.000271442 1 0 BeFree
Involuntary Movements 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Colon Carcinoma 0.000271442 1 0 BeFree
Dystonias, Sporadic 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree
DYSTONIA 1, TORSION, AUTOSOMAL DOMINANT 0.000271442 1 0 BeFree
HUNTINGTON DISEASE-LIKE 1 0.000271442 1 0 BeFree
PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE 0.000271442 1 0 BeFree
Nasopharyngeal carcinoma 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

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