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Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).[supplied by OMIM, Feb 2011]
[中文简述(自动翻译):]  Synaptotagmins,如SYT5,是III型膜蛋白特征与蛋白激酶C细胞质重复的家庭(见MIM 176960)监管(C2)域,这被认为是结合钙。 Synaptotagmins可以充当囊泡融合的既作为负调节,允许融合在钙的存在下,并作为钙受体或传感器分子(由Hudson和伯恩鲍姆,1995 [搜索PubMed 7597049]的摘要)。[由OMIM,2011年2月供给]
SYT5基因(以及对应的蛋白质)的细胞分布位置:
SYT5基因的本体(GO)信息:
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