SRY(sex determining region Y) 转至新版数据库
基因简称(symbol)
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
omim代码
entrez码
vega基因码
ensembl基因码
基因家族(gene family)
refseq数据库代号
更多...
基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库
收起
This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):] 此内含子的基因编码的转录因子，它是高迁移率组（HMG）-box家族DNA结合蛋白中的一员。这种蛋白质是睾丸决定因子（TDF），从而启动男性的决心。在这个基因的突变引起的XY女性与性腺发育不全（Swyer综合征）;含有该基因的X染色体Y染色体的一部分的易位导致XX男性综合征。 [由RefSeq的，2008年7月提供]
SRY基因的碱基突变：
显示全部snp
rs781744002
rs780561417
rs776339584
rs779069000
rs773804421
rs771449441
rs773247144
rs773764555
rs770778716
rs770586680
rs769619586
rs768094734
rs767481926
rs766867548
rs764249635
rs764412387
rs762003265
rs763174397
rs759981348
rs756606002
rs757619452
rs756467546
rs754712640
rs754820786
rs754209742
rs754623064
rs752961669
rs751424595
rs750874990
rs751006997
rs750342498
rs748958243
rs748877650
rs746931713
rs748087062
rs569336697
rs104894971
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AGTATCAGTGTGAAACGGG
57
GGTCGCTTCACTCTATCCT
58
GGAGGCACAGAAATTACAGG
58
AGGTCGATACTTATAATTCGGG
57
AGTATCAGTGTGAAACGGGA
58
GGTCGCTTCACTCTATCCT
58
基因本体信息
SRY基因（以及对应的蛋白质）的细胞分布位置：
- 溶酶体
- 内涵体
- 细胞核
- 细胞质
- 液泡
- 细胞膜
- 细胞外基质
- 内质网
- 线粒体
- 高尔基体
- 细胞骨架
SRY基因的本体（GO）信息：
GO库代码
对应的蛋白质
来源代码
GO:0000122
Q05066(UniProtKB)
IEA
GO:0003677
Q05066(UniProtKB)
IDA
GO:0003677
Q05066(UniProtKB)
IDA
GO:0003705
Q05066(UniProtKB)
IDA
GO:0005516
Q05066(UniProtKB)
IEA
GO:0005634
Q05066(UniProtKB)
NAS
GO:0005634
Q05066(UniProtKB)
IDA
GO:0005634
Q05066(UniProtKB)
NAS
GO:0005654
Q05066(UniProtKB)
TAS
GO:0005737
Q05066(UniProtKB)
IEA
GO:0006351
Q05066(UniProtKB)
IEA
GO:0008134
Q05066(UniProtKB)
IPI
GO:0008134
Q05066(UniProtKB)
IPI
GO:0008134
Q05066(UniProtKB)
IPI
GO:0008134
Q05066(UniProtKB)
IPI
GO:0008134
Q05066(UniProtKB)
IPI
GO:0008134
Q05066(UniProtKB)
IPI
GO:0008134
Q05066(UniProtKB)
IPI
GO:0008134
Q05066(UniProtKB)
IPI
GO:0008134
Q05066(UniProtKB)
IPI
GO:0008134
Q05066(UniProtKB)
IPI
GO:0008134
Q05066(UniProtKB)
IPI
GO:0008301
Q05066(UniProtKB)
IEA
GO:0008584
Q05066(UniProtKB)
IEA
GO:0016607
Q05066(UniProtKB)
IEA
GO:0030154
Q05066(UniProtKB)
IEA
GO:0030238
Q05066(UniProtKB)
NAS
GO:0044798
Q05066(UniProtKB)
IEA
GO:0045893
Q05066(UniProtKB)
IDA
GO:0046982
Q05066(UniProtKB)
IEA
GO:2000020
Q05066(UniProtKB)
IDA
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| 46,Xy Gonadal Dysgenesis, Complete, Sry-Related | 0.36 | 22 | 20 | CLINVAR_CTD_human_UNIPROT |
| Ovotesticular Disorders of Sex Development | 0.24408156 | 6 | 0 | BeFree_CTD_human_LHGDN_ORPHANET |
| XX males | 0.128143256 | 30 | 0 | BeFree_ORPHANET |
| Swyer Syndrome | 0.125624334 | 12 | 0 | BeFree_GAD_ORPHANET |
| 46, XX Testicular Disorders of Sex Development | 0.122714419 | 10 | 0 | BeFree_ORPHANET |
| 46,Xy True Hermaphroditism, Sry-Related | 0.12 | 0 | 1 | CLINVAR |
| Gonadal Dysgenesis | 0.017130633 | 36 | 4 | BeFree_LHGDN |
| Turner Syndrome | 0.012757768 | 47 | 4 | BeFree |
| Gonadal Dysgenesis, 46,XY | 0.007881746 | 19 | 0 | BeFree_LHGDN |
| 46, XY female | 0.007328931 | 27 | 1 | BeFree |
| HIV Infections | 0.005971721 | 22 | 0 | BeFree |
| True Hermaphroditism (disorder) | 0.004885954 | 18 | 0 | BeFree |
| Pure gonadal dysgenesis | 0.003800186 | 14 | 0 | BeFree |
| Hypospadias | 0.003452799 | 5 | 0 | BeFree_GAD |
| Male infertility | 0.002995792 | 1 | 0 | BeFree_LHGDN |
| Virilism | 0.002985861 | 11 | 0 | BeFree |
| Ambiguous Genitalia | 0.002985861 | 11 | 0 | BeFree |
| Infertility | 0.00272435 | 1 | 0 | LHGDN |
| Gonadoblastoma | 0.002171535 | 8 | 0 | BeFree |
| Gonadal Dysgenesis, Mixed | 0.001900093 | 7 | 0 | BeFree |
| Disorders of Sex Development | 0.001900093 | 7 | 0 | BeFree |
| Carcinogenesis | 0.001628651 | 6 | 0 | BeFree |
| Hepatitis B | 0.001357209 | 5 | 0 | BeFree |
| Malignant neoplasm of prostate | 0.001357209 | 5 | 0 | BeFree |
| Prostate carcinoma | 0.001357209 | 5 | 0 | BeFree |
| CAMPOMELIC DYSPLASIA | 0.001357209 | 5 | 0 | BeFree |
| Malignant neoplasm of breast | 0.001085767 | 4 | 0 | BeFree |
| Decompression Sickness | 0.001085767 | 4 | 0 | BeFree |
| Nephroblastoma | 0.001085767 | 4 | 0 | BeFree |
| Streak gonad | 0.001085767 | 4 | 0 | BeFree |
| Breast Carcinoma | 0.001085767 | 4 | 0 | BeFree |
| Azoospermia | 0.000814326 | 3 | 0 | BeFree |
| Colorectal Carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Klinefelter Syndrome | 0.000814326 | 3 | 0 | BeFree |
| Schizophrenia | 0.000814326 | 3 | 1 | BeFree |
| 46, XX true hermaphrodite | 0.000814326 | 3 | 0 | BeFree |
| Colorectal Cancer | 0.000814326 | 3 | 0 | BeFree |
| Penile hypospadias | 0.000814326 | 3 | 0 | BeFree |
| Liver carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Congenital adrenal hyperplasia | 0.000542884 | 2 | 0 | BeFree |
| Squamous cell carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Congenital chromosomal disease | 0.000542884 | 2 | 0 | BeFree |
| Scleroderma | 0.000542884 | 2 | 0 | BeFree |
| Dysgerminoma | 0.000542884 | 2 | 0 | BeFree |
| Hermaphroditism | 0.000542884 | 2 | 0 | BeFree |
| Muscular Dystrophy | 0.000542884 | 2 | 0 | BeFree |
| Nausea | 0.000542884 | 2 | 0 | BeFree |
| Placental Insufficiency | 0.000542884 | 2 | 0 | BeFree |
| Systemic Scleroderma | 0.000542884 | 2 | 0 | BeFree |
| Trisomy X syndrome | 0.000542884 | 2 | 0 | BeFree |
| Pancreatic carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of pancreas | 0.000542884 | 2 | 0 | BeFree |
| Klinefelter's syndrome - male with more than two X chromosomes | 0.000542884 | 2 | 0 | BeFree |
| Testicular Feminization | 0.000542884 | 2 | 0 | BeFree |
| Primary hypogonadism | 0.000542884 | 2 | 0 | BeFree |
| Congenital absence of both testes | 0.000542884 | 2 | 0 | BeFree |
| 46, XY Disorders of Sex Development | 0.000542884 | 2 | 0 | BeFree |
| Testicular dysgenesis syndrome | 0.000542884 | 2 | 0 | BeFree |
| 46, XX Disorders of Sex Development | 0.000542884 | 2 | 0 | BeFree |
| Arteriosclerosis | 0.000271442 | 1 | 0 | BeFree |
| Rheumatoid Arthritis | 0.000271442 | 1 | 0 | BeFree |
| Atherosclerosis | 0.000271442 | 1 | 0 | BeFree |
| Adenocarcinoma of prostate | 0.000271442 | 1 | 0 | BeFree |
| Non-Small Cell Lung Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Malignant tumor of cervix | 0.000271442 | 1 | 0 | BeFree |
| Connective Tissue Diseases | 0.000271442 | 1 | 0 | BeFree |
| Diabetes | 0.000271442 | 1 | 0 | BeFree |
| Diabetes Mellitus | 0.000271442 | 1 | 0 | BeFree |
| Dizziness | 0.000271442 | 1 | 0 | BeFree |
| Dwarfism | 0.000271442 | 1 | 0 | BeFree |
| Eclampsia | 0.000271442 | 1 | 0 | BeFree |
| Yolk Sac Tumor | 0.000271442 | 1 | 1 | BeFree |
| Fragile X Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Graft-vs-Host Disease | 0.000271442 | 1 | 0 | BeFree |
| Chronic granulomatous disease | 0.000271442 | 1 | 0 | BeFree |
| Hirschsprung Disease | 0.000271442 | 1 | 0 | BeFree |
| Hypertensive disease | 0.000271442 | 1 | 0 | BeFree |
| Hypopituitarism | 0.000271442 | 1 | 0 | BeFree |
| Lymphoma, Non-Hodgkin | 0.000271442 | 1 | 0 | BeFree |
| melanoma | 0.000271442 | 1 | 0 | BeFree |
| Neuroblastoma | 0.000271442 | 1 | 0 | BeFree |
| Obesity | 0.000271442 | 1 | 0 | BeFree |
| Oligospermia | 0.000271442 | 1 | 0 | BeFree |
| Precancerous Conditions | 0.000271442 | 1 | 0 | BeFree |
| Rett Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Sertoli Cell Tumor | 0.000271442 | 1 | 0 | BeFree |
| Sex Chromosome Aberrations | 0.000271442 | 1 | 0 | BeFree |
| Teratoma | 0.000271442 | 1 | 0 | BeFree |
| Androgen-Insensitivity Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Vertigo | 0.000271442 | 1 | 0 | BeFree |
| Squamous cell carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
| Small cell carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
| Testicular hypogonadism | 0.000271442 | 1 | 0 | BeFree |
| Hypertrophy of clitoris | 0.000271442 | 1 | 0 | BeFree |
| Tumor Progression | 0.000271442 | 1 | 0 | BeFree |
| Dream disorder | 0.000271442 | 1 | 0 | BeFree |
| Gonadal Dysgenesis, 45,X | 0.000271442 | 1 | 0 | BeFree |
| Multiple tumors | 0.000271442 | 1 | 0 | BeFree |
| Acardiac monster | 0.000271442 | 1 | 0 | BeFree |
| Hypogonadotropic hypogonadism | 0.000271442 | 1 | 0 | BeFree |
| Cervical Squamous Cell Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Solid tumour | 0.000271442 | 1 | 0 | BeFree |
| Cervix carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse | 0.000271442 | 1 | 0 | BeFree |
| Acute HIV infection | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of liver | 0.000271442 | 1 | 0 | BeFree |
| Keratoderma with scleroatrophy of the extremities | 0.000271442 | 1 | 0 | BeFree |
| Sleeplessness | 0.000271442 | 1 | 0 | BeFree |
| Frasier Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Primary testicular failure | 0.000271442 | 1 | 0 | BeFree |
| Congenital absence of germinal epithelium of testes | 0.000271442 | 1 | 0 | BeFree |
| WAARDENBURG SYNDROME, TYPE 4A | 0.000271442 | 1 | 0 | BeFree |
| Coronary Artery Disease | 0.000271442 | 1 | 0 | BeFree |
| Intersex Conditions | 0.000271442 | 1 | 0 | BeFree |
| Hirschsprung disease 1 | 0.000271442 | 1 | 0 | BeFree |
Sex-determining region Y (SRY) in a patient with 46,XX true hermaphroditism.
10.1007/BF01883323
Sex-chromosome pairing and activity during mammalian meiosis.
10.1002/bies.950141205
Sex-chromosome pairing and activity during mammalian meiosis.
10.1002/bies.950141205
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