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This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. This human-specific locus resulted from segmental duplication of the SLIT-ROBO Rho GTPase activating protein 2B locus. The encoded protein lacks the GTPase activating protein domain compared to proteins encoded by SLIT-ROBO Rho GTPase activating protein 2, and acts antagonistically to these proteins in cortical neuron development. [provided by RefSeq, Dec 2012]
[中文简述(自动翻译):]  这座编码狭缝ROBO的Rho GTP酶激活蛋白家族的一个成员。这种人类特有的基因产生于SLIT-ROBO的Rho GTP酶的片段复制激活蛋白基因2B。相比由SLIT-ROBO的Rho GTP酶活化蛋白2编码的蛋白质所编码的蛋白质缺乏GTP酶激活蛋白域,拮抗作用是在皮层神经元发育这些蛋白质。 [由RefSeq的,2012年12月提供]
SRGAP2C基因(以及对应的蛋白质)的细胞分布位置:
SRGAP2C基因的本体(GO)信息:
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