SRF(serum response factor (c-fos serum response element-binding transcription factor)) 转至新版数据库
基因简称(symbol)
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
omim代码
entrez码
vega基因码
ensembl基因码
基因家族(gene family)
refseq数据库代号
更多...
基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库
收起
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
[中文简述(自动翻译):] 这个基因编码刺激既细胞增殖和分化一个无处不在的核蛋白质。它是MADS（MCM1，AGAMOUS，Deficiens和SRF）的转录因子盒超家族的成员。这种蛋白质结合在靶基因的启动子区域的血清应答元件（SRE）。该蛋白质调节的许多立即早期基因的活性，例如c-fos的，从而在细胞周期调控，细胞凋亡，细胞生长和细胞分化参与。这种基因是许多途径的下游靶标;例如，通过三元复杂的因素（TCFs中）作用在丝裂原活化蛋白激酶通路（MAPK）。已发现该基因编码不同亚型的两个转录变异体。 [由RefSeq的，2014年5月提供]
SRF基因的碱基突变：
显示全部snp
rs9395
rs3734681
rs3734682
rs6933869
rs13210208
rs41274924
rs55848540
rs78734542
rs116032487
rs137993584
rs146964345
rs181102628
rs183507239
rs184493910
rs186596236
rs189540775
rs189759968
rs192636381
rs193087582
rs376666214
rs528022670
rs528920250
rs531247933
rs533601779
rs533787295
rs535881874
rs537829840
rs539914909
rs540025420
rs541836215
rs544045398
rs544059443
rs549299058
rs549366319
rs551206201
rs553532425
rs555470444
rs559972491
rs563889221
rs564746468
rs566835582
rs571024483
rs576713719
rs577509293
rs2275070
rs3730363
rs4711741
rs6902679
rs6914964
rs9394944
rs9462872
rs9472021
rs10948066
rs28730660
rs35574424
rs57014925
rs59063320
rs59146246
rs62417513
rs62417514
rs72867556
rs73436476
rs73736720
rs73736721
rs73736722
rs73736723
rs74585888
rs75733842
rs76568282
rs76774759
rs78554687
rs78975247
rs79411640
rs111773489
rs111903566
rs112496612
rs112542835
rs112596376
rs112653102
rs114238645
rs114591244
rs116488658
rs116728249
rs137942943
rs139252004
rs139891953
rs140003532
rs140186009
rs140390001
rs140615670
rs140856577
rs140883192
rs141213290
rs141992873
rs142020494
rs142279506
rs142415999
rs142698332
rs142776066
rs143135540
rs143195021
rs144177872
rs145938368
rs145981327
rs146365693
rs146543379
rs146562071
rs146671770
rs146806717
rs146928461
rs147834555
rs148814396
rs149393478
rs149812713
rs150385837
rs150684295
rs150685392
rs150997102
rs180819797
rs181447938
rs182195361
rs182454585
rs183252794
rs183278667
rs184131028
rs184730888
rs185117990
rs185179643
rs186414179
rs186612858
rs186639275
rs186936425
rs187173611
rs188790992
rs189475899
rs189508478
rs190310712
rs191225393
rs191469511
rs191844171
rs191887441
rs192593765
rs192971989
rs193002570
rs199852197
rs200166395
rs200766084
rs200834264
rs200869123
rs200924365
rs200947906
rs201298273
rs201322755
rs201446058
rs201461031
rs201503404
rs201527826
rs201994269
rs368203115
rs368344477
rs368529052
rs368934437
rs369087749
rs369116248
rs369842787
rs370035723
rs370218229
rs370939499
rs371305681
rs371763251
rs371767534
rs372321247
rs372388096
rs373298629
rs373306943
rs373478811
rs373567050
rs373630083
rs374619996
rs375380910
rs375694237
rs376007675
rs376046050
rs376272545
rs376273062
rs377164533
rs377168498
rs377334269
rs377431701
rs377482725
rs377617547
rs398048474
rs528954571
rs529025033
rs529515173
rs530066068
rs530199128
rs530534849
rs530645780
rs530760919
rs530822769
rs531297218
rs531579734
rs531841358
rs532420531
rs532467410
rs532634178
rs532858955
rs532892350
rs532925075
rs532931511
rs533858782
rs533967128
rs534667437
rs534731485
rs534998574
rs535118405
rs535273153
rs535902908
rs536487430
rs536688853
rs537102728
rs537172656
rs537229453
rs537704673
rs538280896
rs539078296
rs539514410
rs539901783
rs539961381
rs540097494
rs541002303
rs541077769
rs542221739
rs542920417
rs543012020
rs543463839
rs543977867
rs544452108
rs544658252
rs546176552
rs546189101
rs546204793
rs546251468
rs546266257
rs546280309
rs546376204
rs547217961
rs547377083
rs547389520
rs548413700
rs548419488
rs548476532
rs548562090
rs548878533
rs548984189
rs549304557
rs549560432
rs550547236
rs550735171
rs551073767
rs552413334
rs552473833
rs552520304
rs552548323
rs552550415
rs553418088
rs553532380
rs553593887
rs554396250
rs554748335
rs554859996
rs554882140
rs556747300
rs557282319
rs557529980
rs557585459
rs557741168
rs557866835
rs558711788
rs558740316
rs558848086
rs559738690
rs559801470
rs559857889
rs559870040
rs560386274
rs560798978
rs561354706
rs561754773
rs561868372
rs562109207
rs562649754
rs562901302
rs563144066
rs563657077
rs563661816
rs563876627
rs564138960
rs564257131
rs564887424
rs565079465
rs565089041
rs565785538
rs565846200
rs566024076
rs566076296
rs566088351
rs566098706
rs566210658
rs566813628
rs567511279
rs568109882
rs568132894
rs568214451
rs568277913
rs568709023
rs569228668
rs569888837
rs570343739
rs570492273
rs570963011
rs571035667
rs571201939
rs571273625
rs571386276
rs572040989
rs572276165
rs572448368
rs573065323
rs573246806
rs573419799
rs573474230
rs574138642
rs574898429
rs574950017
rs575556882
rs576331257
rs577270264
rs577333967
rs577407564
rs577521400
rs745883078
rs745973752
rs745990378
rs746327291
rs746430949
rs746440806
rs746492753
rs746688970
rs747014595
rs747042101
rs747104734
rs747292367
rs747599471
rs747601402
rs747881923
rs748196511
rs748289428
rs748379657
rs748460414
rs748750154
rs748842180
rs749016780
rs749218962
rs749245986
rs749685699
rs749863011
rs749897577
rs750314662
rs750414610
rs750551550
rs750655050
rs751251776
rs751888054
rs752189541
rs752264862
rs752358551
rs752461122
rs752598928
rs752943356
rs753046057
rs753133969
rs753209061
rs753225736
rs753300038
rs753637015
rs753813882
rs754096646
rs754174160
rs754186126
rs754374964
rs754513269
rs754615401
rs754750407
rs754831478
rs754832739
rs755100692
rs755958575
rs755987567
rs756209842
rs756224105
rs756446140
rs756600547
rs757076353
rs757510553
rs757512731
rs757707235
rs757730577
rs757830199
rs757850825
rs758106997
rs758166629
rs758641072
rs758692854
rs758776381
rs758834986
rs759104795
rs759259114
rs759400989
rs759591573
rs759793226
rs759915913
rs760171428
rs760201969
rs760243435
rs760691850
rs760732415
rs760883275
rs761124326
rs761312027
rs761326401
rs761628822
rs761736012
rs761821794
rs761973193
rs762266039
rs762462366
rs762509796
rs762551523
rs762675693
rs763406737
rs763641879
rs763747728
rs763768924
rs763868264
rs764289630
rs764447416
rs764683399
rs764689206
rs764816664
rs764876728
rs765089960
rs765178182
rs765475250
rs765592889
rs765863665
rs766063329
rs766247883
rs766337868
rs766360318
rs766455944
rs766522779
rs766686839
rs766805589
rs766936639
rs766983445
rs767353248
rs767389851
rs767436023
rs767585389
rs767649010
rs767703965
rs767783421
rs767967535
rs768506308
rs768588222
rs768819977
rs769599078
rs769770702
rs769802191
rs769843247
rs769942003
rs770030447
rs770210193
rs770437907
rs770442653
rs770650422
rs770931382
rs771021246
rs771109122
rs771167599
rs771201292
rs771583062
rs771615419
rs771919205
rs772024181
rs772298484
rs772560438
rs772659060
rs772836061
rs772854310
rs773271428
rs773291512
rs773318743
rs773408842
rs773783498
rs773984127
rs774043864
rs774136408
rs774171725
rs774553319
rs774568148
rs774573847
rs775108603
rs775185364
rs775312812
rs775690451
rs775870143
rs775959317
rs776515081
rs776693970
rs776696350
rs776714858
rs777014183
rs777387840
rs777483568
rs777584646
rs777958010
rs778050935
rs778140208
rs778151242
rs778641767
rs778816086
rs778845009
rs779196150
rs779197453
rs779320183
rs779384289
rs779852507
rs780039871
rs780050786
rs780476860
rs780562633
rs780564597
rs780915393
rs781169138
rs781249667
rs781456757
rs781585222
rs869241817
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TGAAGAAGGCCTATGAGCT
58
GTATACACATGGCCTGTCTC
58
TGAAGAAGGCCTATGAGCTG
60
TATACACATGGCCTGTCTCAC
60
CATGAAGAAGGCCTATGAGC
59
TACACATGGCCTGTCTCAC
59
基因本体信息
SRF基因（以及对应的蛋白质）的细胞分布位置：
- 溶酶体
- 内涵体
- 细胞核
- 细胞质
- 液泡
- 细胞膜
- 细胞外基质
- 内质网
- 线粒体
- 高尔基体
- 细胞骨架
SRF基因的本体（GO）信息：
GO库代码
对应的蛋白质
来源代码
GO:0000790
P11831(UniProtKB)
IEA
GO:0000978
P11831(UniProtKB)
ISS
GO:0001076
P11831(UniProtKB)
IEA
GO:0001077
P11831(UniProtKB)
IDA
GO:0001228
P11831(UniProtKB)
ISS
GO:0001569
P11831(UniProtKB)
IEA
GO:0001666
P11831(UniProtKB)
IEP
GO:0001707
P11831(UniProtKB)
IEA
GO:0001764
P11831(UniProtKB)
IEA
GO:0001829
P11831(UniProtKB)
IDA
GO:0001947
P11831(UniProtKB)
ISS
GO:0002011
P11831(UniProtKB)
IEA
GO:0002042
P11831(UniProtKB)
IMP
GO:0003257
P11831(UniProtKB)
IGI
GO:0003700
P11831(UniProtKB)
IDA
GO:0003705
P11831(UniProtKB)
IEA
GO:0005515
P11831(UniProtKB)
IPI
GO:0005515
P11831(UniProtKB)
IPI
GO:0005515
P11831(UniProtKB)
IPI
GO:0005515
P11831(UniProtKB)
IPI
GO:0005515
P11831(UniProtKB)
IPI
GO:0005515
P11831(UniProtKB)
IPI
GO:0005515
P11831(UniProtKB)
IPI
GO:0005515
P11831(UniProtKB)
IPI
GO:0005515
P11831(UniProtKB)
IPI
GO:0005515
P11831(UniProtKB)
IPI
GO:0005515
P11831(UniProtKB)
IPI
GO:0005515
P11831(UniProtKB)
IPI
GO:0005634
P11831(UniProtKB)
IDA
GO:0005654
P11831(UniProtKB)
TAS
GO:0005654
P11831(UniProtKB)
TAS
GO:0005654
P11831(UniProtKB)
TAS
GO:0005737
P11831(UniProtKB)
TAS
GO:0006366
P11831(UniProtKB)
IDA
GO:0007160
P11831(UniProtKB)
IEA
GO:0007507
P11831(UniProtKB)
ISS
GO:0007616
P11831(UniProtKB)
IEA
GO:0008134
P11831(UniProtKB)
IPI
GO:0008134
P11831(UniProtKB)
IPI
GO:0008285
P11831(UniProtKB)
IEA
GO:0008306
P11831(UniProtKB)
IEA
GO:0009636
P11831(UniProtKB)
TAS
GO:0009725
P11831(UniProtKB)
IDA
GO:0010669
P11831(UniProtKB)
IEA
GO:0010735
P11831(UniProtKB)
IDA
GO:0010735
P11831(UniProtKB)
IDA
GO:0010736
P11831(UniProtKB)
IDA
GO:0021766
P11831(UniProtKB)
IEA
GO:0022028
P11831(UniProtKB)
IEA
GO:0030155
P11831(UniProtKB)
IEA
GO:0030168
P11831(UniProtKB)
IEA
GO:0030220
P11831(UniProtKB)
IEA
GO:0030336
P11831(UniProtKB)
IEA
GO:0030878
P11831(UniProtKB)
IEA
GO:0031175
P11831(UniProtKB)
IEA
GO:0031490
P11831(UniProtKB)
IEA
GO:0033561
P11831(UniProtKB)
IEA
GO:0034097
P11831(UniProtKB)
IMP
GO:0034097
P11831(UniProtKB)
NAS
GO:0035855
P11831(UniProtKB)
IEA
GO:0035912
P11831(UniProtKB)
IEA
GO:0042789
P11831(UniProtKB)
ISS
GO:0042803
P11831(UniProtKB)
IPI
GO:0042826
P11831(UniProtKB)
IEA
GO:0043149
P11831(UniProtKB)
IEA
GO:0043589
P11831(UniProtKB)
IEA
GO:0045059
P11831(UniProtKB)
IEA
GO:0045214
P11831(UniProtKB)
IEA
GO:0045597
P11831(UniProtKB)
IDA
GO:0045773
P11831(UniProtKB)
IEA
GO:0045944
P11831(UniProtKB)
IDA
GO:0045944
P11831(UniProtKB)
IDA
GO:0045987
P11831(UniProtKB)
IDA
GO:0046016
P11831(UniProtKB)
IEA
GO:0046716
P11831(UniProtKB)
ISS
GO:0048538
P11831(UniProtKB)
IEA
GO:0048589
P11831(UniProtKB)
IEA
GO:0048666
P11831(UniProtKB)
TAS
GO:0048821
P11831(UniProtKB)
IEA
GO:0051091
P11831(UniProtKB)
IDA
GO:0051150
P11831(UniProtKB)
TAS
GO:0051491
P11831(UniProtKB)
IEA
GO:0055003
P11831(UniProtKB)
IEA
GO:0060055
P11831(UniProtKB)
TAS
GO:0060218
P11831(UniProtKB)
IEA
GO:0060261
P11831(UniProtKB)
IDA
GO:0060292
P11831(UniProtKB)
IEA
GO:0060324
P11831(UniProtKB)
IEA
GO:0060347
P11831(UniProtKB)
IEA
GO:0060425
P11831(UniProtKB)
IEA
GO:0060532
P11831(UniProtKB)
IEA
GO:0060534
P11831(UniProtKB)
IEA
GO:0060947
P11831(UniProtKB)
IEA
GO:0061029
P11831(UniProtKB)
IEA
GO:0061145
P11831(UniProtKB)
IEA
GO:0070830
P11831(UniProtKB)
IEA
GO:0070878
P11831(UniProtKB)
ISS
GO:0071333
P11831(UniProtKB)
IEA
GO:0090009
P11831(UniProtKB)
IEA
GO:0090136
P11831(UniProtKB)
IEA
GO:0090398
P11831(UniProtKB)
IMP
GO:1900222
P11831(UniProtKB)
IMP
GO:1902894
P11831(UniProtKB)
ISS
GO:1902895
P11831(UniProtKB)
ISS
GO:0000983
P11831(UniProtKB)
IMP
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| HIV Infections | 0.12 | 1 | 0 | CTD_human |
| Liver carcinoma | 0.081357209 | 6 | 0 | BeFree_RGD |
| Hypertensive disease | 0.08 | 1 | 0 | RGD |
| Lymphangioleiomyomatosis | 0.003267234 | 2 | 0 | BeFree_LHGDN |
| Prostatic Neoplasms | 0.002995792 | 2 | 0 | BeFree_LHGDN |
| Alzheimer's Disease | 0.002367032 | 1 | 0 | GAD |
| Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
| Malignant neoplasm of prostate | 0.002171535 | 8 | 1 | BeFree |
| Prostate carcinoma | 0.002171535 | 8 | 1 | BeFree |
| Acute Megakaryocytic Leukemias | 0.001628651 | 6 | 0 | BeFree |
| Heart failure | 0.001357209 | 5 | 0 | BeFree |
| Congestive heart failure | 0.001357209 | 5 | 0 | BeFree |
| Carcinogenesis | 0.001357209 | 5 | 0 | BeFree |
| Cardiomyopathy, Dilated | 0.000814326 | 3 | 0 | BeFree |
| Neoplasm Metastasis | 0.000814326 | 3 | 0 | BeFree |
| Stomach Carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Pulmonary lymphangioleiomyomatosis | 0.000542884 | 2 | 0 | BeFree |
| Rheumatoid Arthritis | 0.000271442 | 1 | 0 | BeFree |
| Non-Small Cell Lung Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma, Papillary | 0.000271442 | 1 | 0 | BeFree |
| Mental Depression | 0.000271442 | 1 | 0 | BeFree |
| Depressive disorder | 0.000271442 | 1 | 0 | BeFree |
| Enterovirus Infections | 0.000271442 | 1 | 0 | BeFree |
| Epilepsy | 0.000271442 | 1 | 0 | BeFree |
| Friedreich Ataxia | 0.000271442 | 1 | 0 | BeFree |
| Immune System Diseases | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of stomach | 0.000271442 | 1 | 0 | BeFree |
| Microcephaly | 0.000271442 | 1 | 0 | BeFree |
| Myelodysplasia | 0.000271442 | 1 | 0 | BeFree |
| Myelomonocytic leukemia | 0.000271442 | 1 | 0 | BeFree |
| Preleukemia | 0.000271442 | 1 | 0 | BeFree |
| Psoriasis | 0.000271442 | 1 | 0 | BeFree |
| Systemic Scleroderma | 0.000271442 | 1 | 0 | BeFree |
| Seizures | 0.000271442 | 1 | 0 | BeFree |
| Dermatologic disorders | 0.000271442 | 1 | 0 | BeFree |
| Status Epilepticus | 0.000271442 | 1 | 0 | BeFree |
| Stomach Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Gastric ulcer | 0.000271442 | 1 | 0 | BeFree |
| Cerebrovascular accident | 0.000271442 | 1 | 0 | BeFree |
| Urethral Stricture | 0.000271442 | 1 | 0 | BeFree |
| Vascular Diseases | 0.000271442 | 1 | 0 | BeFree |
| Thyroid Gland Follicular Adenoma | 0.000271442 | 1 | 0 | BeFree |
| Secondary malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
| Secondary malignant neoplasm of bone | 0.000271442 | 1 | 0 | BeFree |
| Tumor Progression | 0.000271442 | 1 | 0 | BeFree |
| Follicular adenoma | 0.000271442 | 1 | 0 | BeFree |
| Anaplastic carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Undifferentiated carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Myopathies, Nemaline | 0.000271442 | 1 | 0 | BeFree |
| Premature aging syndrome | 0.000271442 | 1 | 0 | BeFree |
| Papillary thyroid carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Adenomatous goiter | 0.000271442 | 1 | 0 | BeFree |
| Cardiac defects | 0.000271442 | 1 | 0 | BeFree |
| social stress | 0.000271442 | 1 | 0 | BeFree |
| Cardiomyopathies | 0.000271442 | 1 | 0 | BeFree |
| Ischemic stroke | 0.000271442 | 1 | 0 | BeFree |
| Cardiac fibrosis | 0.000271442 | 1 | 0 | BeFree |
| Hepatocarcinogenesis | 0.000271442 | 1 | 0 | BeFree |
| Cancer Cell Growth | 0.000271442 | 1 | 0 | BeFree |
| Benign Prostatic Hyperplasia | 0.000271442 | 1 | 0 | BeFree |
| Invasive Skin Melanoma | 0.000271442 | 1 | 0 | BeFree |
| SMITH-MCCORT DYSPLASIA | 0.000271442 | 1 | 0 | BeFree |
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