SPO11(SPO11 meiotic protein covalently bound to DSB) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

20q13.31
基因染色体位置图

基因简述

基因简述

Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  减数分裂重组和染色体分离需要配对的同源染色体双链断裂（DNA双链断裂）的形成。期间在酵母减数分裂，一个减数分裂重组蛋白质是共价连接到双链断裂的5‘端，并且是双链断裂的形成是必不可少的。由该基因编码的蛋白质是在序列和保守特征的酵母减数分裂重组蛋白相似。所编码的蛋白质属于TOP6A蛋白家族。几个转录变体编码不同同种型已发现这种基因，但其中只有两个全长性质已有描述。 [由RefSeq的，2008年7月提供]

OMIM数据库中对SPO11基因的介绍     Wikipedia数据库中对SPO11基因的介绍

基因序列

基因序列

SPO11基因的碱基序列：[NCBI]

基因突变

基因突变

SPO11基因的碱基突变：           显示全部snp
rs1467581       rs2236330       rs3736832       rs3764674       rs4810063       rs5842167       rs6014977       rs6014978       rs6025494       rs6064528       rs6064530       rs6064531       rs6070065       rs6070066       rs6070067       rs6070068       rs6092460       rs6092461       rs6099551       rs6099552       rs6099553       rs6099558       rs6099559       rs6099560       rs6128002       rs6128009       rs7509423       rs11476029       rs11906856       rs16980888       rs16980890       rs16980893       rs16980896       rs16980898       rs16980916       rs17406460       rs28368059      
rs28368061       rs28368062       rs28368063       rs28368064       rs28368065       rs28368066       rs28368067       rs28368069       rs28368070       rs28368071       rs28368072       rs28368073       rs28368074       rs28368075       rs28368076       rs28368077       rs28368078       rs28368079       rs28368080       rs28368081       rs28368082       rs28368083       rs28368084       rs28368085       rs28368086       rs28368087       rs28368088       rs28368089       rs28368090       rs28368091       rs28368092       rs28368093       rs28368094       rs28368095       rs28368096       rs28368097       rs28368098       rs28368099       rs28368100       rs28368101       rs28368102       rs28368103       rs28368104       rs28368105       rs28368106       rs28368107       rs34703560       rs35213336       rs57343077       rs62204166       rs62204168       rs72486602       rs73291807       rs75098623       rs75714022       rs75776586       rs76864875       rs77455943       rs77807031       rs78357692       rs79564060       rs79952093       rs111226724       rs111245214       rs111443258       rs111497391       rs111678121       rs111908685       rs111918864       rs112269358       rs112279729       rs112311252       rs112390286       rs112436875       rs112844497       rs112970460       rs113034458       rs113245162       rs113359273       rs113456122       rs113577344       rs113935004       rs113966274       rs114405858       rs114615100       rs115255314       rs115830696       rs116259400       rs116286539       rs116341523       rs116979306       rs117212102       rs137997364       rs137999916       rs138453752       rs138628462       rs138697435       rs138819150       rs139319079       rs139668948       rs139915989       rs139944699       rs140053442       rs140127120       rs140166023       rs140338503       rs140422206       rs140465905       rs140572912       rs141048663       rs141106732       rs141270656       rs141385031       rs141535481       rs141643931       rs142280709       rs142411510       rs142684036       rs142757116       rs142999149       rs143068216       rs143191648       rs143528288       rs143552011       rs144372733       rs144390880       rs144436142       rs144516785       rs144865285       rs145003891       rs145045956       rs145615340       rs145627694       rs145689165       rs145771904       rs145784599       rs145913253       rs146006834       rs146123252       rs146164727       rs146585263       rs146857630       rs147139080       rs147571833       rs147634675       rs148234267       rs149324083       rs149448187       rs149849607       rs150318111       rs150374893       rs150719853       rs150842681       rs151303106       rs180683636       rs181064063       rs181329544       rs181716081       rs181926570       rs182043723       rs182088597       rs182302226       rs182645593       rs183006575       rs183097670       rs183152940       rs183352291       rs183704511       rs184776193       rs184794969       rs184927275       rs185169121       rs185434357       rs185545661       rs185741379       rs185793420       rs186390721       rs186418995       rs186513204       rs186684695       rs187265091       rs187539754       rs187557668       rs188002663       rs188082380       rs188376504       rs188440288       rs188463071       rs188498297       rs189249987       rs189739775       rs189975642       rs189993248       rs190799034       rs190890748       rs190907136       rs191686534       rs192050224       rs192193332       rs192520751       rs192642273       rs193197335       rs199559830       rs199575818       rs199671760       rs199897475       rs200007444       rs200114220       rs200430445       rs200440718       rs200889214       rs200975452       rs201164098       rs201339461       rs201852448       rs201937576       rs202141631       rs367605105       rs367916594       rs367953716       rs368668611       rs368866973       rs369163483       rs369438731       rs370355278       rs370477685       rs370535430       rs370615184       rs370661600       rs371281831       rs371443486       rs371859511       rs372224637       rs372668001       rs372929790       rs374287657       rs374455093       rs374482597       rs375092006       rs375310857       rs375369929       rs375566386       rs376365150       rs376454938       rs377361570       rs377412083       rs377577002       rs377613467       rs397844296       rs397865965       rs527296870       rs527682532       rs527759825       rs527819418       rs528340718       rs528342590       rs528478076       rs529149151       rs529280236       rs529434724       rs529788775       rs530227135       rs530685078       rs531037660       rs531187679       rs531198633       rs531328707       rs531812541       rs531999489       rs532124409       rs532271092       rs532589416       rs532631556       rs532768027       rs532862136       rs533167154       rs533498680       rs533771428       rs534096163       rs534500361       rs534500430       rs534730956       rs535286538       rs535357227       rs536113128       rs536305476       rs536368908       rs536620465       rs536687054       rs536700440       rs536851393       rs537164713       rs537300124       rs537359840       rs538105857       rs538233224       rs538240433       rs538696876       rs538955195       rs539674945       rs539701059       rs539834710       rs540275501       rs540474465       rs540530363       rs540663960       rs540668088       rs540678285       rs540782394       rs541189490       rs541469748       rs541515579       rs541585169       rs541618742       rs541759911       rs541871944       rs542425902       rs542471713       rs542716214       rs543130491       rs543651080       rs543919320       rs544513613       rs545042653       rs545289247       rs545423377       rs546018279       rs546675739       rs546722170       rs546753723       rs546759585       rs546854487       rs546894825       rs547347172       rs547363905       rs547764946       rs547917592       rs547925006       rs548054464       rs548396383       rs548539424       rs548709870       rs548732489       rs548749830       rs548796455       rs548870069       rs549085833       rs549397131       rs549599503       rs549679904       rs550181432       rs550193062       rs550732985       rs550800656       rs550869906       rs551127039       rs551190878       rs551342986       rs551933893       rs552186921       rs552323353       rs552411087       rs552472788       rs552540188       rs552902271       rs552965092       rs553041548       rs553180578       rs554099175       rs554212520       rs554347728       rs554692118       rs554895089       rs554899295       rs554913960       rs555036124       rs555374344       rs555982059       rs556196817       rs556298434       rs556355771       rs556644278       rs556655034       rs556754656       rs556889447       rs556891733       rs556950571       rs557239120       rs557300525       rs557417900       rs557440972       rs557441799       rs557577428       rs557644031       rs557672908       rs557770291       rs557840137       rs558503548       rs558632954       rs558886344       rs559220304       rs559275800       rs559712778       rs560151331       rs560408500       rs560870324       rs560953229       rs561020382       rs561225151       rs561397312       rs562203837       rs562263035       rs562304419       rs562462782       rs562600879       rs562820607       rs562831365       rs562980277       rs563620626       rs563623892       rs563718480       rs563770910       rs563771172       rs563837215       rs563935001       rs564423128       rs564434939       rs564888078       rs565498132       rs565559807       rs565827167       rs566434050       rs566498132       rs566568538       rs566680939       rs566938450       rs567231719       rs567255792       rs567287248       rs567344895       rs567472432       rs567522555       rs567907241       rs568521053       rs568546052       rs568576835       rs568608223       rs569061507       rs569163059       rs569375774       rs569516363       rs569658652       rs569825893       rs569971353       rs570456529       rs570883340       rs571889044       rs572089600       rs572166639       rs572684775       rs572819842       rs572895379       rs572910113       rs573046025       rs573050141       rs573394250       rs573559775       rs573763445       rs573842923       rs574035150       rs574180169       rs574659770       rs574695623       rs574779203       rs574834421       rs574908007       rs575341288       rs575464993       rs575688240       rs575695367       rs576301517       rs576624281       rs576700689       rs576973695       rs577111328       rs577257322       rs577303826       rs577358203       rs577432274       rs577495044       rs577708425       rs745513856       rs745603850       rs745605702       rs745793621       rs745836622       rs746170555       rs746582279       rs746660064       rs746667607       rs746688977       rs746749994       rs746992170       rs747032832       rs747056632       rs747283179       rs747289934       rs747321941       rs747557397       rs747609402       rs747800414       rs747819852       rs748034051       rs748447975       rs748450310       rs748628168       rs748683456       rs748746060       rs749058928       rs749153579       rs749163353       rs749455830       rs749497675       rs749547810       rs749811010       rs749863814       rs750024829       rs750122191       rs750663128       rs750733758       rs750747124       rs750920190       rs751008594       rs751139158       rs751249489       rs751252053       rs751496564       rs751532703       rs751806535       rs752035116       rs752098155       rs752269876       rs752388584       rs752476754       rs752709076       rs752883793       rs752933283       rs753266523       rs753411233       rs753478196       rs753560072       rs753752651       rs753773211       rs753803297       rs754159968       rs754164090       rs754279151       rs754390722       rs754403439       rs754693897       rs754774447       rs754821585       rs754932051       rs755040198       rs755057866       rs755299888       rs755309591       rs755550172       rs755668199       rs755899909       rs756159611       rs756179301       rs756200828       rs756297740       rs756400544       rs756701075       rs756794313       rs756815894       rs757254817       rs757344510       rs757585150       rs757817919       rs757949652       rs758166626       rs758221386       rs758531602       rs758763384       rs758789088       rs758798269       rs758834544       rs758851313       rs759003934       rs759136906       rs759181801       rs759277309       rs759475640       rs759552686       rs759737151       rs759951296       rs759963007       rs760001093       rs760107334       rs760128185       rs760150768       rs760192298       rs760369826       rs760507790       rs760742526       rs761105888       rs761235091       rs761340956       rs761410004       rs761525351       rs761592445       rs761599179       rs761662774       rs761714114       rs761756353       rs761838727       rs761843544       rs761860382       rs761891793       rs761964189       rs762074238       rs762470206       rs762610314       rs762663685       rs762889018       rs762949955       rs762984592       rs763088587       rs763366388       rs763420260       rs763500942       rs763545083       rs763599835       rs763623722       rs763793597       rs764153498       rs764155602       rs764206819       rs764245350       rs764361442       rs764604119       rs764687841       rs764749126       rs764893123       rs765112555       rs765122452       rs765292847       rs765343975       rs765459923       rs765572171       rs765747732       rs765806190       rs765891906       rs766002529       rs766072958       rs766175887       rs766224343       rs766342648       rs766508457       rs766655895       rs766697859       rs766832858       rs766893897       rs766997603       rs766999648       rs767089680       rs767297621       rs767336068       rs767419409       rs767472660       rs767577963       rs767632574       rs767720205       rs767802376       rs768091468       rs768124093       rs768289200       rs768361261       rs768565887       rs768566109       rs768716192       rs768807497       rs769042547       rs769329269       rs769457009       rs769465007       rs769753902       rs769791952       rs769932072       rs769953784       rs770108439       rs770363386       rs770427206       rs770688545       rs770891797       rs771124735       rs771168294       rs771278060       rs771315659       rs771317121       rs771337883       rs771495651       rs771636264       rs771645199       rs771822884       rs771874270       rs771898854       rs772080202       rs772310274       rs772310926       rs772393532       rs772459798       rs772768747       rs772911189       rs773040526       rs773128846       rs773186617       rs773236395       rs773297972       rs773413127       rs773612199       rs773827506       rs773829185       rs773874276       rs774187978       rs774256082       rs774348218       rs774385826       rs774547691       rs774635696       rs774648389       rs774938108       rs774957467       rs775008768       rs775018422       rs775082697       rs775257764       rs775538760       rs775667706       rs775675999       rs775712791       rs776012127       rs776079065       rs776273934       rs776421375       rs776680181       rs776680379       rs776733259       rs776805995       rs777175607       rs777487846       rs777516529       rs777560356       rs777662976       rs777722559       rs777754739       rs777816132       rs778543206       rs778633160       rs778773370       rs778828288       rs779142011       rs779238568       rs779386207       rs779725255       rs779973554       rs780342271       rs780377200       rs780432207       rs780432223       rs780462735       rs780495429       rs780550427       rs780860543       rs781125742       rs781236665       rs781542289       rs781625229       rs781628705       rs781661760      

基因表达

基因表达

SPO11基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TCATGATTACGGGAAAGGGAG
60
CAGGAACATGAAATGTATCCCAC
60
CTGAAATCCAAGGGAAAGGG
59
AGGAACATGAAATGTATCCCAC
59
CCAAAGTGAATTGTACCTGTG
58
ACTTTGCATCTGTAATCCGA
57
TCATGATTACGGGAAAGGGAG
60
CAGGAACATGAAATGTATCCCAC
60
CATGATTACGGGAAAGGGAG
58
ACAGGAACATGAAATGTATCCC
59
GGAAGATGGCACCAAAGTG
59
ACTTTGCATTCCGAATTCCT
58
GCACCAAAGTGAATTGTACCT
59
TTGCATCTGTAATCCGAATTCC
59
GAAATCCAAGGGAAAGGGAG
58
ACAGGAACATGAAATGTATCCC
59
AAGTGAATTGTACCTGTGGTG
59
CAAACTTTGCATCTGTAATCCG
59
GCACCAAAGTGAATTGTACCT
59
CAAACTTTGCATTCCGAATTCC
60

转录因子

转录因子

      尚未收录相关数据

基因本体信息

SPO11基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
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SPO11基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000737
H0YCK9(UniProtKB)
IEA
GO:0003677
H0YCK9(UniProtKB)
IEA
GO:0005694
H0YCK9(UniProtKB)
IEA
GO:0000737
Q5TCH6(UniProtKB)
IEA
GO:0003677
Q5TCH6(UniProtKB)
IEA
GO:0003824
Q5TCH6(UniProtKB)
IEA
GO:0005524
Q5TCH6(UniProtKB)
IEA
GO:0005694
Q5TCH6(UniProtKB)
IEA
GO:0007131
Q5TCH6(UniProtKB)
IEA
GO:0000737
Q5TCH7(UniProtKB)
IEA
GO:0003677
Q5TCH7(UniProtKB)
IEA
GO:0003824
Q5TCH7(UniProtKB)
IEA
GO:0005524
Q5TCH7(UniProtKB)
IEA
GO:0005694
Q5TCH7(UniProtKB)
IEA
GO:0007131
Q5TCH7(UniProtKB)
IEA
GO:0000737
Q9Y5K1(UniProtKB)
IEA
GO:0000781
Q9Y5K1(UniProtKB)
IEA
GO:0001541
Q9Y5K1(UniProtKB)
IEA
GO:0003677
Q9Y5K1(UniProtKB)
IEA
GO:0003918
Q9Y5K1(UniProtKB)
IEA
GO:0005515
Q9Y5K1(UniProtKB)
IPI
GO:0005524
Q9Y5K1(UniProtKB)
IEA
GO:0005634
Q9Y5K1(UniProtKB)
IEA
GO:0007130
Q9Y5K1(UniProtKB)
IEA
GO:0007131
Q9Y5K1(UniProtKB)
IEA
GO:0007141
Q9Y5K1(UniProtKB)
IEA
GO:0007283
Q9Y5K1(UniProtKB)
TAS
GO:0007286
Q9Y5K1(UniProtKB)
IEA
GO:0007292
Q9Y5K1(UniProtKB)
TAS
GO:0034502
Q9Y5K1(UniProtKB)
IEA
GO:0045141
Q9Y5K1(UniProtKB)
IEA
GO:0046872
Q9Y5K1(UniProtKB)
IEA
GO:0048477
Q9Y5K1(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控SPO11基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Male infertility 0.002909916 3 1 BeFree_GAD
Azoospermia 0.002638474 2 0 BeFree_GAD
Oligospermia 0.002638474 2 0 BeFree_GAD
Ovarian Failure, Premature 0.002638474 1 0 BeFree_GAD
Tobacco Use Disorder 0.002367032 1 0 GAD
Leukemia, Myelocytic, Acute 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

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