SPIB(Spi-B transcription factor (Spi-1/PU.1 related))

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

19q13.3-q13.4
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene is a transcriptional activator that binds to the PU-box (5'-GAGGAA-3') and acts as a lymphoid-specific enhancer. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

[中文简述(自动翻译):]  由该基因编码的蛋白质是结合到PU-盒（5‘-GAGGAA-3‘），并作为一个淋巴特异性增强子的转录激活。已发现该基因编码不同亚型四个抄本变形。 [由RefSeq的，2011年9月提供]

OMIM数据库中对SPIB基因的介绍     Wikipedia数据库中对SPIB基因的介绍

基因序列

基因序列

SPIB基因的碱基序列：[NCBI]

基因突变

基因突变

SPIB基因的碱基突变：           显示全部snp
rs77397362       rs116593415       rs118177825       rs190344184       rs371796757       rs372740836       rs376687030       rs547424704       rs549838796       rs557906719       rs566153908       rs576360099       rs2272323       rs2445837       rs2445839       rs2463238       rs2463239       rs3212330       rs3218758       rs3218765       rs3218766       rs3219448       rs3219449       rs3219450       rs3219451       rs3219452       rs3219453       rs3219454       rs3219455       rs3219456       rs3219457       rs3219459       rs3219460       rs3219461       rs3219462       rs55633346       rs62113958      
rs112856489       rs113202925       rs115073727       rs117012238       rs117035256       rs142223599       rs142879475       rs149742605       rs182231620       rs199871683       rs199899233       rs200284426       rs201139477       rs201325496       rs201933770       rs202091056       rs367766963       rs368535638       rs369354335       rs369358279       rs369535710       rs371194967       rs372257133       rs373397790       rs373910727       rs374168125       rs375062208       rs375328523       rs375490101       rs376468859       rs376581180       rs376662261       rs376862907       rs527887852       rs528028395       rs529203604       rs529479241       rs530246033       rs531771052       rs533696732       rs535554678       rs535619337       rs537726083       rs540119238       rs540182212       rs541931950       rs541995344       rs542768576       rs546386626       rs550641583       rs552897529       rs553845458       rs558381808       rs558589433       rs560246011       rs562159543       rs564579674       rs564648280       rs565533682       rs567133743       rs568346591       rs569395274       rs569987101       rs572691136       rs572828398       rs575352161       rs575387524       rs577037167       rs577298015       rs745432886       rs745737815       rs746377890       rs746682079       rs746897122       rs747122361       rs748304578       rs748398408       rs749722222       rs750366769       rs751088347       rs752322850       rs752376126       rs753235009       rs753290096       rs753455508       rs754507612       rs754530436       rs755297873       rs755458518       rs755695606       rs756232002       rs756287064       rs757102306       rs757442072       rs759019419       rs759477141       rs759650325       rs760161040       rs760214407       rs760766848       rs760961826       rs761465465       rs761614971       rs762090110       rs762698172       rs762828545       rs762920108       rs763799482       rs763951036       rs765079746       rs765926891       rs766669368       rs766728942       rs767002660       rs767945344       rs768651527       rs768747132       rs769314899       rs769560485       rs770660636       rs770739007       rs771255148       rs771819177       rs772054340       rs772170575       rs772397517       rs773088677       rs773382425       rs774127655       rs774141043       rs774175513       rs774835713       rs775364537       rs775451481       rs775803321       rs776152622       rs776167760       rs777018011       rs777958191       rs778190445       rs778990190       rs779208942       rs780592984       rs780749621       rs780885120       rs781356552       rs781762349       rs1137891       rs1137894       rs1137895       rs1274613       rs1274614       rs1274615       rs1295779       rs1673030       rs1673031       rs1726773       rs2244095       rs2463237       rs2463244       rs2607239       rs2695119       rs3745516       rs4462711       rs4517889       rs4802705       rs8102583       rs8108811       rs8110668       rs10405003       rs10412860       rs11084013       rs11084014       rs11546996       rs11666527       rs11878296       rs11881051       rs11881145       rs11881294       rs12978475       rs34084075       rs34795041       rs34944112       rs45464394       rs55919517       rs56043616       rs56204470       rs56234204       rs56235776       rs56300011       rs57005972       rs61729811       rs62113959       rs62116060       rs62116061       rs62116062       rs66579172       rs71332003       rs73072070       rs74394325       rs74690669       rs74885640       rs75530108       rs75557930       rs76521311       rs77284512       rs77779859       rs79030898       rs79248543       rs79448115       rs80162089       rs80198614       rs111450722       rs111491183       rs111695335       rs112162232       rs112201001       rs112528377       rs112787272       rs113133595       rs113184169       rs113339577       rs113427503       rs113813852       rs113958708       rs114377434       rs115234664       rs116190027       rs116382633       rs116692704       rs116774483       rs117090800       rs137904842       rs137911744       rs138290130       rs138351974       rs138535393       rs138842113       rs138958222       rs139027495       rs139263729       rs139810433       rs140102901       rs140485354       rs140646795       rs140666131       rs141734267       rs141909900       rs141992127       rs142362021       rs142789219       rs142866083       rs142878744       rs143398036       rs143507923       rs143825743       rs143918533       rs144359520       rs144612642       rs144659667       rs144719363       rs145129604       rs145160155       rs145343161       rs145412669       rs145951327       rs146302800       rs146685364       rs146870064       rs147079328       rs147205541       rs147214290       rs147483630       rs147596215       rs147696783       rs148471892       rs148523381       rs149229136       rs149237753       rs149918763       rs149970510       rs150308434       rs150626967       rs151132780       rs180713559       rs180749509       rs180919778       rs181357952       rs182032480       rs182683230       rs182834798       rs182934136       rs182968543       rs183560768       rs183989414       rs184080518       rs184441263       rs184593663       rs185291382       rs185396773       rs185436158       rs185518623       rs185833099       rs185977813       rs186234123       rs186822733       rs186892099       rs187086822       rs188295079       rs188602723       rs188638839       rs189100130       rs189249406       rs189941522       rs190096836       rs190299424       rs190330058       rs190645154       rs191401448       rs191741393       rs192144175       rs192191813       rs192367872       rs192615878       rs193245488       rs199589115       rs200555920       rs200906043       rs200960532       rs201390004       rs201501319       rs201850398       rs367646792       rs368077806       rs368388681       rs368748682       rs368761180       rs369004029       rs369160029       rs369516883       rs369613418       rs369962569       rs369965176       rs370254200       rs370280311       rs370583878       rs371285452       rs371372118       rs371426748       rs371620122       rs372017707       rs372038849       rs372062888       rs372083928       rs372283355       rs372444718       rs372481280       rs372608551       rs372881652       rs372956605       rs372971438       rs373824265       rs374064767       rs374155213       rs374394428       rs374568434       rs374585414       rs375251317       rs375771194       rs375839428       rs375850492       rs375899923       rs376528832       rs376981994       rs377193862       rs377391987       rs377672034       rs377688471       rs527441148       rs527453189       rs527501346       rs527634820       rs527707643       rs527708437       rs527847312       rs529051834       rs529203644       rs529239697       rs529384447       rs529813725       rs530190304       rs530270183       rs530395743       rs530442192       rs530458177       rs530458286       rs530761842       rs530764428       rs530937182       rs531561798       rs531734821       rs532696739       rs532708920       rs532811847       rs532901217       rs533155148       rs533525208       rs533826471       rs534335466       rs534350893       rs534850619       rs535054655       rs535400238       rs535402842       rs535464804       rs535531952       rs536003585       rs536236822       rs536613899       rs536745306       rs536784207       rs536921763       rs537125707       rs537332314       rs537807615       rs537930902       rs537941650       rs538116771       rs538379006       rs538412714       rs538549537       rs538943187       rs538991678       rs539006108       rs539022662       rs539203325       rs539298821       rs539750773       rs539945447       rs540330170       rs540776488       rs541038047       rs541136664       rs541198753       rs542190116       rs542415523       rs542437562       rs542519024       rs542563155       rs543145498       rs543438219       rs543615089       rs543615714       rs543801963       rs543962188       rs544298018       rs544631081       rs545151545       rs545175972       rs545401016       rs545489456       rs545559441       rs546542748       rs546818950       rs547110560       rs547356471       rs547723382       rs547994702       rs548013650       rs548116608       rs548485175       rs548596744       rs548720990       rs548894890       rs549562669       rs549682298       rs549924972       rs550062106       rs550102946       rs550111924       rs550672091       rs551246670       rs551310078       rs551407251       rs551577246       rs552116082       rs552342915       rs552453323       rs552459021       rs552569776       rs552656756       rs553134077       rs553171963       rs553206848       rs553270347       rs553543227       rs553832216       rs553849663       rs554113861       rs554321731       rs554398613       rs555115858       rs555122355       rs555600417       rs555660061       rs556798713       rs556842742       rs556861981       rs556996725       rs557322375       rs557428280       rs557521292       rs557992952       rs558563432       rs558961866       rs559087382       rs559297722       rs559363950       rs559475309       rs559552687       rs559678063       rs560542454       rs560590867       rs560593359       rs560648137       rs561006471       rs561324462       rs561815444       rs561910199       rs562992660       rs563144649       rs563436535       rs564125249       rs564191789       rs564345767       rs564554217       rs564741019       rs564792858       rs564957005       rs565413138       rs565613501       rs565658807       rs566662116       rs566742945       rs566862746       rs566990400       rs567524800       rs568054025       rs568068439       rs568185199       rs568327106       rs568704692       rs568716832       rs568718786       rs569282450       rs569305351       rs569382705       rs569457927       rs569504916       rs569619725       rs570471185       rs570540335       rs570628316       rs570741491       rs570897237       rs571062624       rs571119323       rs571734468       rs571884625       rs572612574       rs572828160       rs573399307       rs573712295       rs573729505       rs573896704       rs574021907       rs574491100       rs574743917       rs574904348       rs575089448       rs575187948       rs575838252       rs576556252       rs576781136       rs577046533       rs577328095       rs577772768       rs577901690       rs578166694       rs745761220       rs745818237       rs746567613       rs746964256       rs747371792       rs747738249       rs747990943       rs748007819       rs748341138       rs748503942       rs748534039       rs748732446       rs748960282       rs749027444       rs749151974       rs749812323       rs749969748       rs750284669       rs750585778       rs750621251       rs750673739       rs751175582       rs751180315       rs751378581       rs751424302       rs751758356       rs752065882       rs752116984       rs752489578       rs752637941       rs752895780       rs752985548       rs753059873       rs753549499       rs753800267       rs753857292       rs753955411       rs754090545       rs754570841       rs754930066       rs755140902       rs755290861       rs755544665       rs755719665       rs755929568       rs755944464       rs756420728       rs756505597       rs756849503       rs756915284       rs757584010       rs757637136       rs757896143       rs758156441       rs758209463       rs758438087       rs758782333       rs758882487       rs759045275       rs759092242       rs759346785       rs760090920       rs760253097       rs760432321       rs760711322       rs761106907       rs761195055       rs761304894       rs761775109       rs761875825       rs762393916       rs762655908       rs763069830       rs763400116       rs763933098       rs764093238       rs764244637       rs765181026       rs765361482       rs765431943       rs765780718       rs765824495       rs765873102       rs766022607       rs766402287       rs766545698       rs766612414       rs766811424       rs766961022       rs767360558       rs767406134       rs767692009       rs768003511       rs768128987       rs768180468       rs768419998       rs768576006       rs768599051       rs768642065       rs768880277       rs769043111       rs769164655       rs769481358       rs769582985       rs769641536       rs769815768       rs769877061       rs770122616       rs770272384       rs770607430       rs770969995       rs771007384       rs771436421       rs771571725       rs772054354       rs772165674       rs772520030       rs772940778       rs772972458       rs773006030       rs773054847       rs773340227       rs773340304       rs773478984       rs773679489       rs774243420       rs774916964       rs774923235       rs775593347       rs775746202       rs775840864       rs776114728       rs776379228       rs776510344       rs776630853       rs776792176       rs777082964       rs777216701       rs777349190       rs777412692       rs777594389       rs778109814       rs778274737       rs778609502       rs778756578       rs778842563       rs779231259       rs779334188       rs779468992       rs779622966       rs779754050       rs779781694       rs780014480       rs780114688       rs780243736       rs780410385       rs780846613       rs780991062       rs781188244       rs781243495       rs781570702      

基因表达

基因表达

SPIB基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CTTCAGCTGTCTGTACCCA
59
GTAGCTGGAATGCTTGCAG
59
CTTCAGCTGTCTGTACCCA
59
GTAGCTGGAATGCTTGCAG
59
CTTCAGCTGTCTGTACCCA
59
GTAGCTGGAATGCTTGCAG
59
GCTGTCTGTACCCAGATGG
60
CTTCCTCCTCTGATAGCACAG
60
ACACTTCAGCTGTCTGTACC
60
CCCTCTGAATCAGGGTAGC
59
GCTGTCTGTACCCAGATGG
60
CTCCTCTGATAGCACAGGG
59
TTCAGCTGTCTGTACCCAG
59
GTAGCTGGAATGCTTGCAG
59
TTCAGCTGTCTGTACCCAG
59
GTAGCTGGAATGCTTGCAG
59
ACACTTCAGCTGTCTGTACC
60
CCCTCTGAATCAGGGTAGC
59
GCTGTCTGTACCCAGATGG
60
CCTCCTCTGATAGCACAGG
59

转录因子

转录因子

转录因子
影响类型
PubMed链接
CD40
Activation
10823830
IRF7
Repression
22698399

基因本体信息

SPIB基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

SPIB基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000981
Q01892(UniProtKB)
IBA
GO:0005634
Q01892(UniProtKB)
IBA
GO:0005737
Q01892(UniProtKB)
TAS
GO:0006351
Q01892(UniProtKB)
IEA
GO:0006357
Q01892(UniProtKB)
TAS
GO:0030154
Q01892(UniProtKB)
IBA
GO:0043565
Q01892(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控SPIB基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Primary biliary cirrhosis 0.240542884 4 1 BeFree_GWASCAT_ORPHANET
Biliary cirrhosis 0.124734064 2 1 CTD_human_GAD
Hanot's cirrhosis 0.12 0 0 ORPHANET
Leukoencephalopathy, Progressive Multifocal 0.000542884 2 0 BeFree
Diffuse Large B-Cell Lymphoma 0.000542884 2 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
leukemia 0.000271442 1 0 BeFree
Acute Erythroblastic Leukemia 0.000271442 1 0 BeFree
Waldenstrom Macroglobulinemia 0.000271442 1 0 BeFree
Malignant neoplasm of stomach 0.000271442 1 0 BeFree
T-Cell Lymphoma 0.000271442 1 0 BeFree
Stomach Carcinoma 0.000271442 1 0 BeFree
Activated B-Cell-Like Diffuse Large B-Cell Lymphoma 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree

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