更多...
收起
This gene encodes a member of the SNF subfamily of helicase proteins. The encoded protein plays a critical role in the restoration of heterochromatin organization and propagation of epigenetic patterns following DNA replication by mediating histone H3/H4 deacetylation. Mutations in this gene are associated with adermatoglyphia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
[中文简述(自动翻译):]  该基因编码解旋酶蛋白的SNF亚科的成员。所编码的蛋白质起着通过介导组蛋白H3 / H4乙酰化在异组织和下面的DNA复制后生模式的传播的恢复的关键作用。在这种基因突变与adermatoglyphia相关联。编码多种亚型选择性剪接的转录物变体已经观察到这种基因。 [由RefSeq的,2011年12月提供]
SMARCAD1基因(以及对应的蛋白质)的细胞分布位置:
SMARCAD1基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Fingerprints, Absence of | 0.12 | 0 | 0 | ORPHANET |
Mental disorders | 0.002367032 | 1 | 1 | GAD |
Diabetes Mellitus, Non-Insulin-Dependent | 0.002367032 | 1 | 0 | GAD |
leiomyosarcoma | 0.000271442 | 1 | 0 | BeFree |
Osteosarcoma | 0.000271442 | 1 | 0 | BeFree |
Hematologic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Dermatoglyphs - skin lines | 0.000271442 | 1 | 0 | BeFree |
Osteosarcoma of bone | 0.000271442 | 1 | 0 | BeFree |
Toxic Shock Syndrome | 0.000271442 | 1 | 0 | BeFree |
忘记密码? 点击找回密码.
扫一扫右方二维码,关注微信订阅号,实时查看信息,关注医学生物学动态。