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SMAD4基因(以及对应的蛋白质)的细胞分布位置:
SMAD4基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Juvenile polyposis syndrome | 0.587926175 | 71 | 58 | BeFree_CLINVAR_CTD_human_GAD_MGD_ORPHANET_UNIPROT |
| Growth mental deficiency syndrome of Myhre | 0.481900093 | 7 | 4 | BeFree_CLINVAR_CTD_human_ORPHANET_UNIPROT |
| JUVENILE POLYPOSIS/HEREDITARY HEMORRHAGIC TELANGIECTASIA SYNDROME (disorder) | 0.361085767 | 6 | 21 | BeFree_CLINVAR_CTD_human_UNIPROT |
| Colorectal Neoplasms | 0.14052735 | 15 | 0 | BeFree_CTD_human_GAD_LHGDN |
| Pancreatic carcinoma | 0.139543815 | 72 | 4 | BeFree_CLINVAR |
| Stomach Neoplasms | 0.125091382 | 2 | 0 | CTD_human_GAD_LHGDN |
| Hereditary hemorrhagic telangiectasia | 0.124267125 | 8 | 0 | BeFree_GAD_ORPHANET |
| Neoplastic Syndromes, Hereditary | 0.122367032 | 1 | 17 | CLINVAR_GAD |
| Adenocarcinoma Of Esophagus | 0.121357209 | 5 | 2 | BeFree_CTD_human |
| Cholangiocarcinoma | 0.120542884 | 3 | 0 | BeFree_CTD_human |
| Invasive Ductal Breast Carcinoma | 0.120542884 | 3 | 0 | BeFree_CTD_human |
| Cognition Disorders | 0.12 | 1 | 0 | CTD_human |
| Deafness | 0.12 | 1 | 0 | CTD_human |
| Liver Cirrhosis, Experimental | 0.12 | 1 | 0 | CTD_human |
| Liver Diseases, Parasitic | 0.12 | 1 | 0 | CTD_human |
| Myopathy | 0.12 | 1 | 0 | CTD_human |
| Brachydactyly | 0.12 | 1 | 0 | CTD_human |
| Craniofacial Abnormalities | 0.12 | 1 | 0 | CTD_human |
| JUVENILE POLYPOSIS OF STOMACH | 0.12 | 0 | 0 | CLINVAR |
| Pancreatic carcinoma, familial | 0.12 | 0 | 0 | ORPHANET |
| Adenocarcinoma | 0.032219214 | 35 | 0 | BeFree_GAD_LHGDN |
| Pancreatic Neoplasm | 0.020712916 | 17 | 0 | BeFree_GAD_LHGDN |
| Malignant neoplasm of pancreas | 0.020629582 | 76 | 0 | BeFree |
| Carcinogenesis | 0.018458047 | 68 | 0 | BeFree |
| Colorectal Cancer | 0.017296335 | 56 | 0 | BeFree_GAD |
| Colorectal Carcinoma | 0.015200745 | 56 | 0 | BeFree |
| Neoplasm Metastasis | 0.013863399 | 32 | 0 | BeFree_LHGDN |
| Squamous cell carcinoma | 0.01162585 | 8 | 0 | BeFree_GAD_LHGDN |
| Prostatic Neoplasms | 0.008173051 | 3 | 0 | LHGDN |
| Colonic Neoplasms | 0.006263026 | 5 | 0 | BeFree_LHGDN |
| Mammary Neoplasms | 0.005991584 | 4 | 0 | BeFree_LHGDN |
| Pancreatic Ductal Adenocarcinoma | 0.005428837 | 20 | 0 | BeFree |
| Colon Carcinoma | 0.005157396 | 19 | 0 | BeFree |
| Malignant neoplasm of breast | 0.004885954 | 18 | 0 | BeFree |
| Breast Carcinoma | 0.004885954 | 18 | 0 | BeFree |
| Intestinal Polyposis | 0.004734064 | 2 | 0 | GAD |
| Malignant tumor of colon | 0.00434307 | 16 | 0 | BeFree |
| Tumor Progression | 0.00434307 | 16 | 0 | BeFree |
| Adenocarcinoma of pancreas | 0.00434307 | 16 | 0 | BeFree |
| Stomach Carcinoma | 0.00434307 | 16 | 0 | BeFree |
| Renal Cell Carcinoma | 0.003810118 | 4 | 0 | BeFree_LHGDN |
| Malignant neoplasm of stomach | 0.003800186 | 14 | 0 | BeFree |
| Adenomatous Polyposis Coli | 0.003724241 | 6 | 0 | BeFree_GAD |
| Polyposis, Gastric | 0.003452799 | 4 | 0 | BeFree_GAD |
| Carcinoma, Pancreatic Ductal | 0.003452799 | 5 | 0 | BeFree_GAD |
| Telangiectasis | 0.003267234 | 3 | 0 | BeFree_LHGDN |
| Ductal Carcinoma | 0.003267234 | 2 | 0 | BeFree_LHGDN |
| Ovarian Carcinoma | 0.003257302 | 12 | 0 | BeFree |
| polyps | 0.003257302 | 12 | 0 | BeFree |
| Malignant neoplasm of prostate | 0.003257302 | 12 | 0 | BeFree |
| Noninfiltrating Intraductal Carcinoma | 0.002995792 | 2 | 0 | BeFree_LHGDN |
| Adenoma | 0.002985861 | 11 | 0 | BeFree |
| Prostate carcinoma | 0.002985861 | 11 | 0 | BeFree |
| Malignant neoplasm of ovary | 0.002985861 | 11 | 0 | BeFree |
| Gastrointestinal Neoplasms | 0.002638474 | 2 | 0 | BeFree_GAD |
| Secondary malignant neoplasm of lymph node | 0.002442977 | 9 | 0 | BeFree |
| Liver carcinoma | 0.002442977 | 9 | 0 | BeFree |
| Cleft Palate | 0.002367032 | 1 | 0 | GAD |
| Diabetes Mellitus, Insulin-Dependent | 0.002367032 | 1 | 0 | GAD |
| Hemochromatosis | 0.002367032 | 1 | 0 | GAD |
| Pulmonary Hypertension | 0.002367032 | 1 | 0 | GAD |
| Liver Cirrhosis | 0.002367032 | 1 | 0 | GAD |
| Neoplasms, Germ Cell and Embryonal | 0.002367032 | 1 | 0 | GAD |
| Polycystic Ovary Syndrome | 0.002367032 | 1 | 0 | GAD |
| Testicular Neoplasms | 0.002367032 | 1 | 0 | GAD |
| Gilles de la Tourette syndrome | 0.002367032 | 1 | 0 | GAD |
| Adenosquamous carcinoma | 0.002367032 | 1 | 0 | GAD |
| Hepatopulmonary Syndrome | 0.002367032 | 1 | 0 | GAD |
| Microsatellite Instability | 0.002367032 | 1 | 0 | GAD |
| Malignant neoplasm of gastrointestinal tract | 0.001900093 | 7 | 0 | BeFree |
| Intraepithelial Neoplasia | 0.001900093 | 7 | 0 | BeFree |
| Squamous cell carcinoma of the head and neck | 0.001900093 | 7 | 0 | BeFree |
| Malignant neoplasm of lung | 0.001628651 | 6 | 0 | BeFree |
| Cervix carcinoma | 0.001628651 | 6 | 0 | BeFree |
| Secondary malignant neoplasm of liver | 0.001628651 | 6 | 0 | BeFree |
| Leukemia, Myelocytic, Acute | 0.001357209 | 5 | 0 | BeFree |
| Multiple polyps | 0.001357209 | 5 | 0 | BeFree |
| Malignant neoplasm of skin | 0.001085767 | 4 | 0 | BeFree |
| Malignant tumor of cervix | 0.001085767 | 4 | 0 | BeFree |
| Juvenile polyp | 0.001085767 | 4 | 0 | BeFree |
| Squamous cell carcinoma of esophagus | 0.001085767 | 4 | 0 | BeFree |
| Invasive Carcinoma | 0.001085767 | 4 | 0 | BeFree |
| Congenital arteriovenous malformation | 0.000814326 | 3 | 0 | BeFree |
| Non-Small Cell Lung Carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Colitis | 0.000814326 | 3 | 0 | BeFree |
| leukemia | 0.000814326 | 3 | 0 | BeFree |
| melanoma | 0.000814326 | 3 | 0 | BeFree |
| Peutz-Jeghers Syndrome | 0.000814326 | 3 | 0 | BeFree |
| Pancreatitis, Chronic | 0.000814326 | 3 | 0 | BeFree |
| Esophageal carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Secondary malignant neoplasm of bone | 0.000814326 | 3 | 0 | BeFree |
| Arteriovenous hemangioma | 0.000814326 | 3 | 0 | BeFree |
| Overlap syndrome | 0.000814326 | 3 | 0 | BeFree |
| Endometrial Carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Malignant neoplasm of esophagus | 0.000814326 | 3 | 0 | BeFree |
| Biliary Tract Cancer | 0.000814326 | 3 | 0 | BeFree |
| Pancreatic intraepithelial neoplasia | 0.000814326 | 3 | 0 | BeFree |
| Hereditary Nonpolyposis Colorectal Cancer | 0.000814326 | 3 | 0 | BeFree |
| Rectal Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of thyroid | 0.000542884 | 2 | 0 | BeFree |
| Ulcerative Colitis | 0.000542884 | 2 | 0 | BeFree |
| Esophageal Neoplasms | 0.000542884 | 2 | 0 | BeFree |
| Glioma | 0.000542884 | 2 | 0 | BeFree |
| Hamartoma | 0.000542884 | 2 | 0 | BeFree |
| Hepatitis B | 0.000542884 | 2 | 0 | BeFree |
| Keloid | 0.000542884 | 2 | 0 | BeFree |
| Actinic keratosis | 0.000542884 | 2 | 0 | BeFree |
| Fibroid Tumor | 0.000542884 | 2 | 0 | BeFree |
| Acute Promyelocytic Leukemia | 0.000542884 | 2 | 0 | BeFree |
| Nephroblastoma | 0.000542884 | 2 | 0 | BeFree |
| Neuroblastoma | 0.000542884 | 2 | 0 | BeFree |
| Systemic Scleroderma | 0.000542884 | 2 | 0 | BeFree |
| Thyroid Neoplasm | 0.000542884 | 2 | 0 | BeFree |
| Uterine Fibroids | 0.000542884 | 2 | 0 | BeFree |
| Renal fibrosis | 0.000542884 | 2 | 0 | BeFree |
| Carcinoma, Signet Ring Cell | 0.000542884 | 2 | 0 | BeFree |
| Gallbladder Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Gastric Adenocarcinoma | 0.000542884 | 2 | 0 | BeFree |
| Solid tumour | 0.000542884 | 2 | 0 | BeFree |
| Intrahepatic Cholangiocarcinoma | 0.000542884 | 2 | 0 | BeFree |
| Thyroid carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Epithelial ovarian cancer | 0.000542884 | 2 | 0 | BeFree |
| Stage III Colorectal Cancer | 0.000542884 | 2 | 0 | BeFree |
| Central neuroblastoma | 0.000542884 | 2 | 0 | BeFree |
| Gastric Cardia Adenocarcinoma | 0.000542884 | 2 | 0 | BeFree |
| Vascular lesions | 0.000542884 | 2 | 0 | BeFree |
| Ductal Breast Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Congenital Abnormality | 0.000271442 | 1 | 0 | BeFree |
| Anemia | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of urinary bladder | 0.000271442 | 1 | 0 | BeFree |
| Bone Diseases | 0.000271442 | 1 | 0 | BeFree |
| Carcinoid Tumor | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma, Papillary | 0.000271442 | 1 | 0 | BeFree |
| Uterine Cervical Neoplasm | 0.000271442 | 1 | 0 | BeFree |
| Developmental Disabilities | 0.000271442 | 1 | 0 | BeFree |
| Constipation | 0.000271442 | 1 | 0 | BeFree |
| Dental caries | 0.000271442 | 1 | 0 | BeFree |
| Scleroderma | 0.000271442 | 1 | 0 | BeFree |
| Diabetes Mellitus, Non-Insulin-Dependent | 0.000271442 | 1 | 0 | BeFree |
| Vipoma | 0.000271442 | 1 | 0 | BeFree |
| Subacute Bacterial Endocarditis | 0.000271442 | 1 | 0 | BeFree |
| Endometriosis | 0.000271442 | 1 | 0 | BeFree |
| Fanconi Anemia | 0.000271442 | 1 | 0 | BeFree |
| Cardiac Arrest | 0.000271442 | 1 | 0 | BeFree |
| Herpes Simplex Infections | 0.000271442 | 1 | 0 | BeFree |
| Mammary Ductal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| insulinoma | 0.000271442 | 1 | 0 | BeFree |
| Lichen disease | 0.000271442 | 1 | 0 | BeFree |
| Liver neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Lung Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Lymphatic Metastasis | 0.000271442 | 1 | 0 | BeFree |
| Meningioma | 0.000271442 | 1 | 0 | BeFree |
| Muscular Dystrophy | 0.000271442 | 1 | 0 | BeFree |
| Mycoplasma Infections | 0.000271442 | 1 | 0 | BeFree |
| Precancerous Conditions | 0.000271442 | 1 | 0 | BeFree |
| Pulmonary Fibrosis | 0.000271442 | 1 | 0 | BeFree |
| Rectal polyp | 0.000271442 | 1 | 0 | BeFree |
| Retinoblastoma | 0.000271442 | 1 | 0 | BeFree |
| Retroviridae Infections | 0.000271442 | 1 | 0 | BeFree |
| Rhabdomyosarcoma | 0.000271442 | 1 | 0 | BeFree |
| Seminoma | 0.000271442 | 1 | 0 | BeFree |
| Thrombocythemia, Essential | 0.000271442 | 1 | 0 | BeFree |
| Vascular Diseases | 0.000271442 | 1 | 0 | BeFree |
| Severe Combined Immunodeficiency | 0.000271442 | 1 | 2 | BeFree |
| Abscess of breast | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of mouth | 0.000271442 | 1 | 0 | BeFree |
| Vascular anomaly | 0.000271442 | 1 | 0 | BeFree |
| Acute intermittent porphyria | 0.000271442 | 1 | 0 | BeFree |
| Carcinoid, Goblet Cell | 0.000271442 | 1 | 0 | BeFree |
| Germ cell tumor | 0.000271442 | 1 | 0 | BeFree |
| Rhabdomyosarcoma, Embryonal | 0.000271442 | 1 | 0 | BeFree |
| Acinar Cell Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Cystadenocarcinoma, Mucinous | 0.000271442 | 1 | 0 | BeFree |
| Cystadenoma, Serous | 0.000271442 | 1 | 0 | BeFree |
| Lip and Oral Cavity Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Papillary thyroid carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Islet Cell Tumor | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma, Small Cell | 0.000271442 | 1 | 0 | BeFree |
| Schinzel-Giedion syndrome | 0.000271442 | 1 | 0 | BeFree |
| Chronic colitis | 0.000271442 | 1 | 0 | BeFree |
| Cancer of Head and Neck | 0.000271442 | 1 | 0 | BeFree |
| Anal carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Caries (morphologic abnormality) | 0.000271442 | 1 | 0 | BeFree |
| Carcinoid tumor no ICD-O subtype | 0.000271442 | 1 | 0 | BeFree |
| Adenocarcinoma of colon | 0.000271442 | 1 | 0 | BeFree |
| Multiple malignancy | 0.000271442 | 1 | 0 | BeFree |
| Intestinal Cancer | 0.000271442 | 1 | 0 | BeFree |
| Polyp of duodenum | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma of anal margin | 0.000271442 | 1 | 0 | BeFree |
| Leukemogenesis | 0.000271442 | 1 | 0 | BeFree |
| invasive cancer | 0.000271442 | 1 | 0 | BeFree |
| Stage IV Colorectal Cancer | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma of bladder | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of kidney | 0.000271442 | 1 | 0 | BeFree |
| Poorly differentiated carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Medullary Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Adenomatous polyp of colon | 0.000271442 | 1 | 0 | BeFree |
| Helicobacter pylori infection | 0.000271442 | 1 | 0 | BeFree |
| Adenoviral infections | 0.000271442 | 1 | 0 | BeFree |
| Pancreatic carcinoma resectable | 0.000271442 | 1 | 0 | BeFree |
| Arteriovenous Malformations, Cerebral | 0.000271442 | 1 | 0 | BeFree |
| ovarian neoplasm | 0.000271442 | 1 | 0 | BeFree |
| precancerous lesions | 0.000271442 | 1 | 0 | BeFree |
| Colorectal cancer metastatic | 0.000271442 | 1 | 0 | BeFree |
| Polyp of small intestine | 0.000271442 | 1 | 0 | BeFree |
| Primary Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Renal carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Primary Lesion | 0.000271442 | 1 | 0 | BeFree |
| Skin Carcinogenesis | 0.000271442 | 1 | 0 | BeFree |
| Prostatic Hypertrophy | 0.000271442 | 1 | 0 | BeFree |
| Congenital vascular anomaly | 0.000271442 | 1 | 0 | BeFree |
| Pancreatic islet cell tumors | 0.000271442 | 1 | 0 | BeFree |
| Clear-cell metastatic renal cell carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Stage IV Colorectal Cancer AJCC v7 | 0.000271442 | 1 | 0 | BeFree |
| Gastrointestinal Hamartoma | 0.000271442 | 1 | 0 | BeFree |
| FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) | 0.000271442 | 1 | 0 | BeFree |
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