SMAD4(SMAD family member 4) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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18q21.1
基因染色体位置图
SMAD4基因的碱基序列:[NCBI]
SMAD4基因的碱基突变:           显示全部snp
rs1787110       rs3752063       rs3829616       rs9951928       rs9961921       rs35014537       rs36222037       rs72913244       rs75658003       rs77212176       rs78685185       rs78950659       rs78985558       rs79642020       rs112190235       rs112512652       rs139455628       rs139513536       rs142196376       rs144455191       rs145170795       rs147613425       rs149534722       rs149658113       rs150912768       rs181326256       rs181464168       rs184728259       rs185586676       rs189079805       rs189177661       rs189383531       rs193246988       rs202234353       rs375228441       rs528104505       rs528465246      
rs530717725       rs530779998       rs530805199       rs530847196       rs532626307       rs533316618       rs533557390       rs534058246       rs534372565       rs535203415       rs537319496       rs537356233       rs537860285       rs537947353       rs539754479       rs540072311       rs540145914       rs540157625       rs541737913       rs542639455       rs544505533       rs545545169       rs546996158       rs549099166       rs549453445       rs550520420       rs550756103       rs552365456       rs552784408       rs554957926       rs555375675       rs557084902       rs557246609       rs560192471       rs560265318       rs561710818       rs564643995       rs565923122       rs566468920       rs567041726       rs568452859       rs569010438       rs570695602       rs570850328       rs571811821       rs572747240       rs572855606       rs573757826       rs573768679       rs574936102       rs575329715       rs575333256       rs10470       rs948588       rs948589       rs1049875       rs1539870       rs1801250       rs1942094       rs1942095       rs2156009       rs2276163       rs2282544       rs2298617       rs2427776       rs2427779       rs2427780       rs2509999       rs2510000       rs2510001       rs2960498       rs3220198       rs3764465       rs3764466       rs3819122       rs3838887       rs4318301       rs4588076       rs4939651       rs4940037       rs7229678       rs7231287       rs7238500       rs7240396       rs7243466       rs7504192       rs8083720       rs8084630       rs8084643       rs8086832       rs8089167       rs8089558       rs8094219       rs8096092       rs9304407       rs9797433       rs9807412       rs10164011       rs10164023       rs10502913       rs11287965       rs11352368       rs11419287       rs11660342       rs11662245       rs11663303       rs11663402       rs11875522       rs12326174       rs12326882       rs12326897       rs12327465       rs12453988       rs12455792       rs12456284       rs12457540       rs12458752       rs12606462       rs12954164       rs12956118       rs12958604       rs12959147       rs12960005       rs12961857       rs12965840       rs12968012       rs16952779       rs16952790       rs16952798       rs17663887       rs17811426       rs28403611       rs28539779       rs28601741       rs28836494       rs34008927       rs34344103       rs34861220       rs35029562       rs35325456       rs35752513       rs35764731       rs36061626       rs57590952       rs57847829       rs58874111       rs58990052       rs59795420       rs60096801       rs60894507       rs61232213       rs67325153       rs68159021       rs71171373       rs71171374       rs71357269       rs72913249       rs72913254       rs72913266       rs73436532       rs73436534       rs73436537       rs73960360       rs73960361       rs74169183       rs74178609       rs74178610       rs74253912       rs74355814       rs74357720       rs74510681       rs74601985       rs74878872       rs74972410       rs75017379       rs75054487       rs75060377       rs75089417       rs75103919       rs75125259       rs75193296       rs75330462       rs75485786       rs75526742       rs75584400       rs75609127       rs75666070       rs75667697       rs75712226       rs75913646       rs75979703       rs75998234       rs76019912       rs76020793       rs76096739       rs76247606       rs76545198       rs76642607       rs76821718       rs76830638       rs76833038       rs76944671       rs77182362       rs77310957       rs77337149       rs77379715       rs77389132       rs77428143       rs77507960       rs77525306       rs77538981       rs77617352       rs77684585       rs77889822       rs77930705       rs78015408       rs78321956       rs78407704       rs78460518       rs78502690       rs78599734       rs78751092       rs78801230       rs78888119       rs78995516       rs79051374       rs79157898       rs79208698       rs79294993       rs79403623       rs79638847       rs79696695       rs79864957       rs79955608       rs80002804       rs80276583       rs111349749       rs111604818       rs111648182       rs111741874       rs112044857       rs112355739       rs112428314       rs112458358       rs112518106       rs112533050       rs112739300       rs112891188       rs112992364       rs113048972       rs113155703       rs113180405       rs113228756       rs113248537       rs113293398       rs113344703       rs113394161       rs113545983       rs113585969       rs113663946       rs113698816       rs113917043       rs114163054       rs114235542       rs114291470       rs114298446       rs114424661       rs114450613       rs114512881       rs114634010       rs114637817       rs114852346       rs115310318       rs115409360       rs115914439       rs115944179       rs115963135       rs116086479       rs116156041       rs116197033       rs116290327       rs116347481       rs116421341       rs116488215       rs116489656       rs116575678       rs116602967       rs116813823       rs116895354       rs116967263       rs117057280       rs117142232       rs117469397       rs117524466       rs117682027       rs117731981       rs117789529       rs117802437       rs117817333       rs118185031       rs138073246       rs138224416       rs138276731       rs138279085       rs138386557       rs138404813       rs138406415       rs138411318       rs138439540       rs138662590       rs138704821       rs138741678       rs138800446       rs138909220       rs139172019       rs139264364       rs139266756       rs139316858       rs139414609       rs139476890       rs139501134       rs139526377       rs139565689       rs139569694       rs139595540       rs139741470       rs139741673       rs139869801       rs139940554       rs139948252       rs139987615       rs139995923       rs140069461       rs140241965       rs140280491       rs140301837       rs140348446       rs140350940       rs140416457       rs140487104       rs140511143       rs140683391       rs140743238       rs140778559       rs140846022       rs140881310       rs140885067       rs140896259       rs140926102       rs141149381       rs141247594       rs141309481       rs141381077       rs141420059       rs141478108       rs141705384       rs141717957       rs141776111       rs141801546       rs141824982       rs141880128       rs142012021       rs142181468       rs142236156       rs142292491       rs142461428       rs142558432       rs142735521       rs142749444       rs142914218       rs142915049       rs142956769       rs143058098       rs143082783       rs143136444       rs143137726       rs143240720       rs143318826       rs143406501       rs143497944       rs143533417       rs143535243       rs143559191       rs143563979       rs143733392       rs143842829       rs143883438       rs144187949       rs144226135       rs144328584       rs144340373       rs144378484       rs144510801       rs144547085       rs144611121       rs144699189       rs144717953       rs144758037       rs144795539       rs144880327       rs144999412       rs145011178       rs145047320       rs145081087       rs145097078       rs145105387       rs145208125       rs145288509       rs145290584       rs145384665       rs145503719       rs145596898       rs145643623       rs145650998       rs145741938       rs145801952       rs145805120       rs145988618       rs146006919       rs146104321       rs146124058       rs146165625       rs146176832       rs146285846       rs146360161       rs146371654       rs146528282       rs146546093       rs146551171       rs146622056       rs146660995       rs146670818       rs146682057       rs146785165       rs146788816       rs146792006       rs146919169       rs147016852       rs147026915       rs147126222       rs147145633       rs147174960       rs147352474       rs147457928       rs147493936       rs147621330       rs147817957       rs147827838       rs147924441       rs147932506       rs147985029       rs148159939       rs148187942       rs148190627       rs148310488       rs148318329       rs148369457       rs148415488       rs148484873       rs148628745       rs148687037       rs148777342       rs148892386       rs148945169       rs148949886       rs149096443       rs149148317       rs149170228       rs149218951       rs149335502       rs149392172       rs149424787       rs149541014       rs149638838       rs149711506       rs149711553       rs149743165       rs149755320       rs149860350       rs149865924       rs150004864       rs150179374       rs150184965       rs150229208       rs150301543       rs150444182       rs150505210       rs150556996       rs150621159       rs150652754       rs150708940       rs150722079       rs150773093       rs150946798       rs150998721       rs151083259       rs151212566       rs151298979       rs180745786       rs180975407       rs181027632       rs181178864       rs181186464       rs181201259       rs181213774       rs181250637       rs181270148       rs181276808       rs181302637       rs181317382       rs181403130       rs181489309       rs181530338       rs181664459       rs181675557       rs181717953       rs181802790       rs181866774       rs182092812       rs182143225       rs182158910       rs182403459       rs182419730       rs182490580       rs182497415       rs182506645       rs182612650       rs182690784       rs182735651       rs182739756       rs182939830       rs183036889       rs183096119       rs183114900       rs183255810       rs183331586       rs183336718       rs183372873       rs183379408       rs183472455       rs183573154       rs183785604       rs183843173       rs183888078       rs183895656       rs183959621       rs183971579       rs183971728       rs183978416       rs183984903       rs183996470       rs184023182       rs184204011       rs184231325       rs184294851       rs184516281       rs184533066       rs184671903       rs184700048       rs184706743       rs184717442       rs184760633       rs184766805       rs184859663       rs184994298       rs185002603       rs185010040       rs185010226       rs185104256       rs185228929       rs185236287       rs185244401       rs185349233       rs185386533       rs185404075       rs185468281       rs185518984       rs185896782       rs185996413       rs186016465       rs186020951       rs186026397       rs186093929       rs186234276       rs186237286       rs186277803       rs186295711       rs186324049       rs186332162       rs186343031       rs186411909       rs186751378       rs186764935       rs186777783       rs186785769       rs186807250       rs186818064       rs186823481       rs186843505       rs186880929       rs186888714       rs186933751       rs187018810       rs187090428       rs187352936       rs187360094       rs187383996       rs187397272       rs187400048       rs187412021       rs187523362       rs187594531       rs187863115       rs188119770       rs188228460       rs188248717       rs188293692       rs188424006       rs188570784       rs188634737       rs188797382       rs188832758       rs188908208       rs188913984       rs188915309       rs188923159       rs189135072       rs189148401       rs189154462       rs189251815       rs189410982       rs189449879       rs189459842       rs189463726       rs189468176       rs189547031       rs189557152       rs189565962       rs189700575       rs189904125       rs189938952       rs189960053       rs189995173       rs190039588       rs190043300       rs190076139       rs190201909       rs190294133       rs190334923       rs190477956       rs190506669       rs190609086       rs190742750       rs190844355       rs190853155       rs190860493       rs190902608       rs190977186       rs190982508       rs191101588       rs191208154       rs191217645       rs191223884       rs191229716       rs191234360       rs191236458       rs191317135       rs191391775       rs191403347       rs191624124       rs191631957       rs191637734       rs191650049       rs191655564       rs191822473       rs191901905       rs191914729       rs191937970       rs191974671       rs192121875       rs192142689       rs192211531       rs192473527       rs192485057       rs192532745       rs192536777       rs192605471       rs192788049       rs192873202       rs193000742       rs193060512       rs193063746       rs193131849       rs193139179       rs193237226       rs193294298       rs199511039       rs199526820       rs199667858       rs199755235       rs199790852       rs199809905       rs200181364       rs200236229       rs200331016       rs200386455       rs200595795       rs200717327       rs200772603       rs200778699       rs200973136       rs201092541       rs201228894       rs201239868       rs201296880       rs201683280       rs201924714       rs202126703       rs202134898       rs281875323       rs367832416       rs368065509       rs368121123       rs368388212       rs368528856       rs368754762       rs368959904       rs369040052       rs369241089       rs369598262       rs369894340       rs369978812       rs370033582       rs370152218       rs370176106       rs370468404       rs370515841       rs370726274       rs371117398       rs371193569       rs371222845       rs371536364       rs371628293       rs372089678       rs372095620       rs372249805       rs372316981       rs372320456       rs373122928       rs373141146       rs373373792       rs373469189       rs373599907       rs373729626       rs374018586       rs374327220       rs374562658       rs374687785       rs374916387       rs375129730       rs375185293       rs375313666       rs375580807       rs375695065       rs375856998       rs375910294       rs376371717       rs377119288       rs377767360       rs397518413       rs397686427       rs397787293       rs398032816       rs398032817       rs527269758       rs527318292       rs527368228       rs527379737       rs527421267       rs527426509       rs527523602       rs527536657       rs527584474       rs527679571       rs527837951       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rs755403065       rs755636369       rs755677513       rs755756863       rs755770046       rs755862230       rs755891338       rs756050098       rs756675575       rs756675590       rs756723838       rs756795016       rs756942056       rs757031495       rs757211048       rs757229084       rs757291177       rs757567812       rs757971589       rs757977781       rs758087098       rs758408642       rs758408803       rs758439958       rs758462032       rs758615780       rs758642067       rs758696549       rs758900306       rs759197188       rs759288477       rs759341259       rs759391555       rs759679579       rs759810903       rs759878328       rs760084081       rs760236686       rs760414331       rs760578129       rs760785405       rs760840557       rs760962650       rs760990830       rs761044209       rs761239224       rs761398356       rs761651997       rs761858248       rs761936246       rs761937143       rs762115816       rs762118751       rs762166596       rs762171718       rs762236281       rs762273127       rs762501162       rs762663804       rs762899211       rs762952272       rs763085683       rs763433258       rs763510526       rs763824961       rs763904908       rs764042720       rs764049211       rs764159041       rs764421512       rs764436881       rs764439383       rs764640081       rs764822197       rs764831736       rs764887024       rs765051479       rs765226990       rs765405495       rs765597059       rs765597856       rs765606080       rs765726171       rs766140541       rs766144339       rs766541692       rs766690790       rs766792585       rs766833269       rs767288576       rs767419859       rs767546607       rs767670657       rs767842443       rs768025763       rs768086109       rs768342552       rs768362140       rs768452351       rs768796731       rs768803926       rs768865165       rs768906241       rs769081404       rs769607309       rs769895209       rs769943457       rs770128265       rs770262494       rs770301659       rs770303876       rs770461626       rs770463358       rs770523387       rs770789755       rs770798845       rs770799201       rs771022919       rs771219866       rs771382294       rs771456293       rs771506970       rs771513235       rs771578562       rs771895353       rs771931492       rs772002386       rs772028872       rs772172736       rs772186355       rs772351886       rs772479430       rs772506979       rs772575670       rs772758257       rs773111265       rs773336735       rs773367516       rs773549756       rs773598775       rs773615487       rs773719398       rs773952731       rs773982472       rs774307284       rs774334251       rs774342820       rs774463256       rs774480995       rs774616939       rs774653865       rs774866012       rs775181052       rs775309874       rs775484792       rs775498596       rs775795086       rs776280713       rs776523203       rs776614361       rs776840348       rs776946182       rs776997580       rs777049307       rs777252555       rs777495692       rs777595914       rs777784326       rs777811251       rs777917225       rs778294025       rs778319626       rs778465458       rs778555013       rs778576111       rs778679766       rs778696847       rs778959035       rs779036780       rs779069779       rs779118698       rs779119136       rs779122843       rs779583608       rs779803439       rs779811141       rs780090544       rs780269983       rs780561242       rs780610518       rs780665234       rs780675019       rs780716382       rs781519690       rs781689800       rs869255051      

SMAD4基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ATTGGATGGGAGGCTTCAG
60
ACGGGCATAGATCACATGAG
60
AATTACCCGGATGTGGTCC
60
GTATTCAGGATAACCGCAGC
59
CTAATTTGCCTCACCACCA
58
ATCAAAGACCAGGATGATTGG
58
GGTCTTTGATTTGCGTCAG
57
CTGACAGACTGATAGCTGG
57
TCTTCAGTGTGGTCTGTCAG
59
GTCTTGGGTAATCCGGTCC
60
AAGGTCTTTGATTTGCGTCAG
60
AGTTTAACTTGATAGCTGGAGC
59
GTGTCATCGACAGATGCAG
59
AGTTTAACTTGATAGCTGGAGC
59
AGGTCTTTGATTTGCGTCAG
59
CTGACAGACTGATAGCTGGA
59
ACAGAGACATACAGCACCC
59
TACTCAGGAGTTGTGGAAGC
60
ATGATACAAGAGCAGCTCCA
59
CTTCAGTGGACAACGATGG
59
转录因子
影响类型
PubMed链接
AHR
Unknown
APOC3
Activation
BAMBI
Activation
BCL2
Unknown
BGLAP
Unknown
BTRC
Repression
CDKN1A
Activation
CDKN2B
Unknown
COL7A1
Unknown
DACH1
Repression

SMAD4基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

SMAD4基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0005622
A0A087WUF3(UniProtKB)
IEA
GO:0006355
A0A087WUF3(UniProtKB)
IEA
GO:0003700
K7EIJ2(UniProtKB)
IEA
GO:0005634
K7EIJ2(UniProtKB)
IEA
GO:0005667
K7EIJ2(UniProtKB)
IEA
GO:0006351
K7EIJ2(UniProtKB)
IEA
GO:0006355
K7EIJ2(UniProtKB)
IEA
GO:0007179
K7EIJ2(UniProtKB)
IEA
GO:0003677
K7EIU8(UniProtKB)
IEA
GO:0003700
K7EIU8(UniProtKB)
IEA
GO:0005634
K7EIU8(UniProtKB)
IEA
GO:0005667
K7EIU8(UniProtKB)
IEA
GO:0005737
K7EIU8(UniProtKB)
IEA
GO:0006351
K7EIU8(UniProtKB)
IEA
GO:0006355
K7EIU8(UniProtKB)
IEA
GO:0007179
K7EIU8(UniProtKB)
IEA
GO:0003700
K7EL15(UniProtKB)
IEA
GO:0005634
K7EL15(UniProtKB)
IEA
GO:0005667
K7EL15(UniProtKB)
IEA
GO:0006351
K7EL15(UniProtKB)
IEA
GO:0006355
K7EL15(UniProtKB)
IEA
GO:0007179
K7EL15(UniProtKB)
IEA
GO:0003700
K7EL18(UniProtKB)
IEA
GO:0005634
K7EL18(UniProtKB)
IEA
GO:0005667
K7EL18(UniProtKB)
IEA
GO:0006351
K7EL18(UniProtKB)
IEA
GO:0006355
K7EL18(UniProtKB)
IEA
GO:0007179
K7EL18(UniProtKB)
IEA
GO:0005622
K7ELK2(UniProtKB)
IEA
GO:0006355
K7ELK2(UniProtKB)
IEA
GO:0003700
K7ENG1(UniProtKB)
IEA
GO:0005634
K7ENG1(UniProtKB)
IEA
GO:0005667
K7ENG1(UniProtKB)
IEA
GO:0006351
K7ENG1(UniProtKB)
IEA
GO:0006355
K7ENG1(UniProtKB)
IEA
GO:0007179
K7ENG1(UniProtKB)
IEA
GO:0003700
K7ENG8(UniProtKB)
IEA
GO:0005634
K7ENG8(UniProtKB)
IEA
GO:0005667
K7ENG8(UniProtKB)
IEA
GO:0006351
K7ENG8(UniProtKB)
IEA
GO:0006355
K7ENG8(UniProtKB)
IEA
GO:0007179
K7ENG8(UniProtKB)
IEA
GO:0003700
K7ES96(UniProtKB)
IEA
GO:0005634
K7ES96(UniProtKB)
IEA
GO:0005667
K7ES96(UniProtKB)
IEA
GO:0006351
K7ES96(UniProtKB)
IEA
GO:0006355
K7ES96(UniProtKB)
IEA
GO:0007179
K7ES96(UniProtKB)
IEA
GO:0000122
Q13485(UniProtKB)
ISS
GO:0000122
Q13485(UniProtKB)
ISS
GO:0000122
Q13485(UniProtKB)
TAS
GO:0000790
Q13485(UniProtKB)
IDA
GO:0000978
Q13485(UniProtKB)
IDA
GO:0000987
Q13485(UniProtKB)
IDA
GO:0001076
Q13485(UniProtKB)
IEA
GO:0001077
Q13485(UniProtKB)
IDA
GO:0001085
Q13485(UniProtKB)
IEA
GO:0001541
Q13485(UniProtKB)
IEA
GO:0001658
Q13485(UniProtKB)
IEA
GO:0001666
Q13485(UniProtKB)
IMP
GO:0001701
Q13485(UniProtKB)
IEA
GO:0001702
Q13485(UniProtKB)
IEA
GO:0003190
Q13485(UniProtKB)
IEA
GO:0003198
Q13485(UniProtKB)
IEA
GO:0003251
Q13485(UniProtKB)
IEA
GO:0003279
Q13485(UniProtKB)
IEA
GO:0003360
Q13485(UniProtKB)
IEA
GO:0003682
Q13485(UniProtKB)
IEA
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005515
Q13485(UniProtKB)
IPI
GO:0005518
Q13485(UniProtKB)
IEA
GO:0005634
Q13485(UniProtKB)
IDA
GO:0005634
Q13485(UniProtKB)
IDA
GO:0005634
Q13485(UniProtKB)
IDA
GO:0005634
Q13485(UniProtKB)
IDA
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005654
Q13485(UniProtKB)
TAS
GO:0005667
Q13485(UniProtKB)
IPI
GO:0005667
Q13485(UniProtKB)
IPI
GO:0005667
Q13485(UniProtKB)
IDA
GO:0005737
Q13485(UniProtKB)
IDA
GO:0005737
Q13485(UniProtKB)
IDA
GO:0005737
Q13485(UniProtKB)
IDA
GO:0005829
Q13485(UniProtKB)
TAS
GO:0005829
Q13485(UniProtKB)
TAS
GO:0005829
Q13485(UniProtKB)
TAS
GO:0005829
Q13485(UniProtKB)
TAS
GO:0005829
Q13485(UniProtKB)
TAS
GO:0005829
Q13485(UniProtKB)
TAS
GO:0005829
Q13485(UniProtKB)
TAS
GO:0005829
Q13485(UniProtKB)
TAS
GO:0005829
Q13485(UniProtKB)
TAS
GO:0005829
Q13485(UniProtKB)
TAS
GO:0005829
Q13485(UniProtKB)
TAS
GO:0006366
Q13485(UniProtKB)
IEA
GO:0006879
Q13485(UniProtKB)
ISS
GO:0007179
Q13485(UniProtKB)
ISS
GO:0007179
Q13485(UniProtKB)
IDA
GO:0007179
Q13485(UniProtKB)
IDA
GO:0007179
Q13485(UniProtKB)
TAS
GO:0007183
Q13485(UniProtKB)
IDA
GO:0007283
Q13485(UniProtKB)
IEA
GO:0007338
Q13485(UniProtKB)
IEA
GO:0007411
Q13485(UniProtKB)
IEA
GO:0007492
Q13485(UniProtKB)
IEA
GO:0007498
Q13485(UniProtKB)
IEA
GO:0008283
Q13485(UniProtKB)
IEA
GO:0008285
Q13485(UniProtKB)
IEA
GO:0010718
Q13485(UniProtKB)
ISS
GO:0010862
Q13485(UniProtKB)
ISS
GO:0014033
Q13485(UniProtKB)
IEA
GO:0017015
Q13485(UniProtKB)
IMP
GO:0030308
Q13485(UniProtKB)
IDA
GO:0030509
Q13485(UniProtKB)
ISS
GO:0030509
Q13485(UniProtKB)
IDA
GO:0030509
Q13485(UniProtKB)
TAS
GO:0030511
Q13485(UniProtKB)
IDA
GO:0030513
Q13485(UniProtKB)
IMP
GO:0030616
Q13485(UniProtKB)
IDA
GO:0032444
Q13485(UniProtKB)
IDA
GO:0032525
Q13485(UniProtKB)
IEA
GO:0032909
Q13485(UniProtKB)
IMP
GO:0033686
Q13485(UniProtKB)
IEA
GO:0035019
Q13485(UniProtKB)
TAS
GO:0035556
Q13485(UniProtKB)
IMP
GO:0036302
Q13485(UniProtKB)
IEA
GO:0042118
Q13485(UniProtKB)
IEA
GO:0042733
Q13485(UniProtKB)
IEA
GO:0042802
Q13485(UniProtKB)
IPI
GO:0042802
Q13485(UniProtKB)
IPI
GO:0042802
Q13485(UniProtKB)
IPI
GO:0042803
Q13485(UniProtKB)
IPI
GO:0044212
Q13485(UniProtKB)
IDA
GO:0045892
Q13485(UniProtKB)
IDA
GO:0045893
Q13485(UniProtKB)
IDA
GO:0045893
Q13485(UniProtKB)
IDA
GO:0045893
Q13485(UniProtKB)
IDA
GO:0045893
Q13485(UniProtKB)
IDA
GO:0045893
Q13485(UniProtKB)
IDA
GO:0045944
Q13485(UniProtKB)
ISS
GO:0045944
Q13485(UniProtKB)
ISS
GO:0045944
Q13485(UniProtKB)
IDA
GO:0045944
Q13485(UniProtKB)
IDA
GO:0045944
Q13485(UniProtKB)
TAS
GO:0046872
Q13485(UniProtKB)
IEA
GO:0046881
Q13485(UniProtKB)
IEA
GO:0046982
Q13485(UniProtKB)
IEA
GO:0048589
Q13485(UniProtKB)
IEA
GO:0048663
Q13485(UniProtKB)
IEA
GO:0048733
Q13485(UniProtKB)
IEA
GO:0048859
Q13485(UniProtKB)
IEA
GO:0051098
Q13485(UniProtKB)
IEA
GO:0051571
Q13485(UniProtKB)
ISS
GO:0051797
Q13485(UniProtKB)
IEA
GO:0060021
Q13485(UniProtKB)
ISS
GO:0060065
Q13485(UniProtKB)
IEA
GO:0060391
Q13485(UniProtKB)
ISS
GO:0060395
Q13485(UniProtKB)
IDA
GO:0060395
Q13485(UniProtKB)
IDA
GO:0060548
Q13485(UniProtKB)
IEA
GO:0060956
Q13485(UniProtKB)
IEA
GO:0061040
Q13485(UniProtKB)
IEA
GO:0070102
Q13485(UniProtKB)
ISS
GO:0070411
Q13485(UniProtKB)
IPI
GO:0070412
Q13485(UniProtKB)
IPI
GO:0070412
Q13485(UniProtKB)
IPI
GO:0070412
Q13485(UniProtKB)
IPI
GO:0070412
Q13485(UniProtKB)
IPI
GO:0070412
Q13485(UniProtKB)
IPI
GO:0070412
Q13485(UniProtKB)
IPI
GO:0070412
Q13485(UniProtKB)
IPI
GO:0071141
Q13485(UniProtKB)
IDA
GO:0071559
Q13485(UniProtKB)
IDA
GO:0071773
Q13485(UniProtKB)
NAS
GO:0072133
Q13485(UniProtKB)
IEA
GO:0072134
Q13485(UniProtKB)
IEA
GO:0072520
Q13485(UniProtKB)
IEA
GO:1901522
Q13485(UniProtKB)
TAS
GO:2000617
Q13485(UniProtKB)
ISS
GO:0000988
Q13485(UniProtKB)
IDA
GO:0003677
Q13485(UniProtKB)
IDA
GO:0003700
Q13485(UniProtKB)
IDA
GO:0003700
Q13485(UniProtKB)
IDA
GO:0043565
Q13485(UniProtKB)
IDA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控SMAD4基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Juvenile polyposis syndrome 0.587926175 71 58 BeFree_CLINVAR_CTD_human_GAD_MGD_ORPHANET_UNIPROT
Growth mental deficiency syndrome of Myhre 0.481900093 7 4 BeFree_CLINVAR_CTD_human_ORPHANET_UNIPROT
JUVENILE POLYPOSIS/HEREDITARY HEMORRHAGIC TELANGIECTASIA SYNDROME (disorder) 0.361085767 6 21 BeFree_CLINVAR_CTD_human_UNIPROT
Colorectal Neoplasms 0.14052735 15 0 BeFree_CTD_human_GAD_LHGDN
Pancreatic carcinoma 0.139543815 72 4 BeFree_CLINVAR
Stomach Neoplasms 0.125091382 2 0 CTD_human_GAD_LHGDN
Hereditary hemorrhagic telangiectasia 0.124267125 8 0 BeFree_GAD_ORPHANET
Neoplastic Syndromes, Hereditary 0.122367032 1 17 CLINVAR_GAD
Adenocarcinoma Of Esophagus 0.121357209 5 2 BeFree_CTD_human
Cholangiocarcinoma 0.120542884 3 0 BeFree_CTD_human
Invasive Ductal Breast Carcinoma 0.120542884 3 0 BeFree_CTD_human
Cognition Disorders 0.12 1 0 CTD_human
Deafness 0.12 1 0 CTD_human
Liver Cirrhosis, Experimental 0.12 1 0 CTD_human
Liver Diseases, Parasitic 0.12 1 0 CTD_human
Myopathy 0.12 1 0 CTD_human
Brachydactyly 0.12 1 0 CTD_human
Craniofacial Abnormalities 0.12 1 0 CTD_human
JUVENILE POLYPOSIS OF STOMACH 0.12 0 0 CLINVAR
Pancreatic carcinoma, familial 0.12 0 0 ORPHANET
Adenocarcinoma 0.032219214 35 0 BeFree_GAD_LHGDN
Pancreatic Neoplasm 0.020712916 17 0 BeFree_GAD_LHGDN
Malignant neoplasm of pancreas 0.020629582 76 0 BeFree
Carcinogenesis 0.018458047 68 0 BeFree
Colorectal Cancer 0.017296335 56 0 BeFree_GAD
Colorectal Carcinoma 0.015200745 56 0 BeFree
Neoplasm Metastasis 0.013863399 32 0 BeFree_LHGDN
Squamous cell carcinoma 0.01162585 8 0 BeFree_GAD_LHGDN
Prostatic Neoplasms 0.008173051 3 0 LHGDN
Colonic Neoplasms 0.006263026 5 0 BeFree_LHGDN
Mammary Neoplasms 0.005991584 4 0 BeFree_LHGDN
Pancreatic Ductal Adenocarcinoma 0.005428837 20 0 BeFree
Colon Carcinoma 0.005157396 19 0 BeFree
Malignant neoplasm of breast 0.004885954 18 0 BeFree
Breast Carcinoma 0.004885954 18 0 BeFree
Intestinal Polyposis 0.004734064 2 0 GAD
Malignant tumor of colon 0.00434307 16 0 BeFree
Tumor Progression 0.00434307 16 0 BeFree
Adenocarcinoma of pancreas 0.00434307 16 0 BeFree
Stomach Carcinoma 0.00434307 16 0 BeFree
Renal Cell Carcinoma 0.003810118 4 0 BeFree_LHGDN
Malignant neoplasm of stomach 0.003800186 14 0 BeFree
Adenomatous Polyposis Coli 0.003724241 6 0 BeFree_GAD
Polyposis, Gastric 0.003452799 4 0 BeFree_GAD
Carcinoma, Pancreatic Ductal 0.003452799 5 0 BeFree_GAD
Telangiectasis 0.003267234 3 0 BeFree_LHGDN
Ductal Carcinoma 0.003267234 2 0 BeFree_LHGDN
Ovarian Carcinoma 0.003257302 12 0 BeFree
polyps 0.003257302 12 0 BeFree
Malignant neoplasm of prostate 0.003257302 12 0 BeFree
Noninfiltrating Intraductal Carcinoma 0.002995792 2 0 BeFree_LHGDN
Adenoma 0.002985861 11 0 BeFree
Prostate carcinoma 0.002985861 11 0 BeFree
Malignant neoplasm of ovary 0.002985861 11 0 BeFree
Gastrointestinal Neoplasms 0.002638474 2 0 BeFree_GAD
Secondary malignant neoplasm of lymph node 0.002442977 9 0 BeFree
Liver carcinoma 0.002442977 9 0 BeFree
Cleft Palate 0.002367032 1 0 GAD
Diabetes Mellitus, Insulin-Dependent 0.002367032 1 0 GAD
Hemochromatosis 0.002367032 1 0 GAD
Pulmonary Hypertension 0.002367032 1 0 GAD
Liver Cirrhosis 0.002367032 1 0 GAD
Neoplasms, Germ Cell and Embryonal 0.002367032 1 0 GAD
Polycystic Ovary Syndrome 0.002367032 1 0 GAD
Testicular Neoplasms 0.002367032 1 0 GAD
Gilles de la Tourette syndrome 0.002367032 1 0 GAD
Adenosquamous carcinoma 0.002367032 1 0 GAD
Hepatopulmonary Syndrome 0.002367032 1 0 GAD
Microsatellite Instability 0.002367032 1 0 GAD
Malignant neoplasm of gastrointestinal tract 0.001900093 7 0 BeFree
Intraepithelial Neoplasia 0.001900093 7 0 BeFree
Squamous cell carcinoma of the head and neck 0.001900093 7 0 BeFree
Malignant neoplasm of lung 0.001628651 6 0 BeFree
Cervix carcinoma 0.001628651 6 0 BeFree
Secondary malignant neoplasm of liver 0.001628651 6 0 BeFree
Leukemia, Myelocytic, Acute 0.001357209 5 0 BeFree
Multiple polyps 0.001357209 5 0 BeFree
Malignant neoplasm of skin 0.001085767 4 0 BeFree
Malignant tumor of cervix 0.001085767 4 0 BeFree
Juvenile polyp 0.001085767 4 0 BeFree
Squamous cell carcinoma of esophagus 0.001085767 4 0 BeFree
Invasive Carcinoma 0.001085767 4 0 BeFree
Congenital arteriovenous malformation 0.000814326 3 0 BeFree
Non-Small Cell Lung Carcinoma 0.000814326 3 0 BeFree
Colitis 0.000814326 3 0 BeFree
leukemia 0.000814326 3 0 BeFree
melanoma 0.000814326 3 0 BeFree
Peutz-Jeghers Syndrome 0.000814326 3 0 BeFree
Pancreatitis, Chronic 0.000814326 3 0 BeFree
Esophageal carcinoma 0.000814326 3 0 BeFree
Secondary malignant neoplasm of bone 0.000814326 3 0 BeFree
Arteriovenous hemangioma 0.000814326 3 0 BeFree
Overlap syndrome 0.000814326 3 0 BeFree
Endometrial Carcinoma 0.000814326 3 0 BeFree
Malignant neoplasm of esophagus 0.000814326 3 0 BeFree
Biliary Tract Cancer 0.000814326 3 0 BeFree
Pancreatic intraepithelial neoplasia 0.000814326 3 0 BeFree
Hereditary Nonpolyposis Colorectal Cancer 0.000814326 3 0 BeFree
Rectal Carcinoma 0.000542884 2 0 BeFree
Malignant neoplasm of thyroid 0.000542884 2 0 BeFree
Ulcerative Colitis 0.000542884 2 0 BeFree
Esophageal Neoplasms 0.000542884 2 0 BeFree
Glioma 0.000542884 2 0 BeFree
Hamartoma 0.000542884 2 0 BeFree
Hepatitis B 0.000542884 2 0 BeFree
Keloid 0.000542884 2 0 BeFree
Actinic keratosis 0.000542884 2 0 BeFree
Fibroid Tumor 0.000542884 2 0 BeFree
Acute Promyelocytic Leukemia 0.000542884 2 0 BeFree
Nephroblastoma 0.000542884 2 0 BeFree
Neuroblastoma 0.000542884 2 0 BeFree
Systemic Scleroderma 0.000542884 2 0 BeFree
Thyroid Neoplasm 0.000542884 2 0 BeFree
Uterine Fibroids 0.000542884 2 0 BeFree
Renal fibrosis 0.000542884 2 0 BeFree
Carcinoma, Signet Ring Cell 0.000542884 2 0 BeFree
Gallbladder Carcinoma 0.000542884 2 0 BeFree
Gastric Adenocarcinoma 0.000542884 2 0 BeFree
Solid tumour 0.000542884 2 0 BeFree
Intrahepatic Cholangiocarcinoma 0.000542884 2 0 BeFree
Thyroid carcinoma 0.000542884 2 0 BeFree
Epithelial ovarian cancer 0.000542884 2 0 BeFree
Stage III Colorectal Cancer 0.000542884 2 0 BeFree
Central neuroblastoma 0.000542884 2 0 BeFree
Gastric Cardia Adenocarcinoma 0.000542884 2 0 BeFree
Vascular lesions 0.000542884 2 0 BeFree
Ductal Breast Carcinoma 0.000542884 2 0 BeFree
Congenital Abnormality 0.000271442 1 0 BeFree
Anemia 0.000271442 1 0 BeFree
Malignant neoplasm of urinary bladder 0.000271442 1 0 BeFree
Bone Diseases 0.000271442 1 0 BeFree
Carcinoid Tumor 0.000271442 1 0 BeFree
Carcinoma, Papillary 0.000271442 1 0 BeFree
Uterine Cervical Neoplasm 0.000271442 1 0 BeFree
Developmental Disabilities 0.000271442 1 0 BeFree
Constipation 0.000271442 1 0 BeFree
Dental caries 0.000271442 1 0 BeFree
Scleroderma 0.000271442 1 0 BeFree
Diabetes Mellitus, Non-Insulin-Dependent 0.000271442 1 0 BeFree
Vipoma 0.000271442 1 0 BeFree
Subacute Bacterial Endocarditis 0.000271442 1 0 BeFree
Endometriosis 0.000271442 1 0 BeFree
Fanconi Anemia 0.000271442 1 0 BeFree
Cardiac Arrest 0.000271442 1 0 BeFree
Herpes Simplex Infections 0.000271442 1 0 BeFree
Mammary Ductal Carcinoma 0.000271442 1 0 BeFree
insulinoma 0.000271442 1 0 BeFree
Lichen disease 0.000271442 1 0 BeFree
Liver neoplasms 0.000271442 1 0 BeFree
Lung Neoplasms 0.000271442 1 0 BeFree
Lymphatic Metastasis 0.000271442 1 0 BeFree
Meningioma 0.000271442 1 0 BeFree
Muscular Dystrophy 0.000271442 1 0 BeFree
Mycoplasma Infections 0.000271442 1 0 BeFree
Precancerous Conditions 0.000271442 1 0 BeFree
Pulmonary Fibrosis 0.000271442 1 0 BeFree
Rectal polyp 0.000271442 1 0 BeFree
Retinoblastoma 0.000271442 1 0 BeFree
Retroviridae Infections 0.000271442 1 0 BeFree
Rhabdomyosarcoma 0.000271442 1 0 BeFree
Seminoma 0.000271442 1 0 BeFree
Thrombocythemia, Essential 0.000271442 1 0 BeFree
Vascular Diseases 0.000271442 1 0 BeFree
Severe Combined Immunodeficiency 0.000271442 1 2 BeFree
Abscess of breast 0.000271442 1 0 BeFree
Malignant neoplasm of mouth 0.000271442 1 0 BeFree
Vascular anomaly 0.000271442 1 0 BeFree
Acute intermittent porphyria 0.000271442 1 0 BeFree
Carcinoid, Goblet Cell 0.000271442 1 0 BeFree
Germ cell tumor 0.000271442 1 0 BeFree
Rhabdomyosarcoma, Embryonal 0.000271442 1 0 BeFree
Acinar Cell Carcinoma 0.000271442 1 0 BeFree
Cystadenocarcinoma, Mucinous 0.000271442 1 0 BeFree
Cystadenoma, Serous 0.000271442 1 0 BeFree
Lip and Oral Cavity Carcinoma 0.000271442 1 0 BeFree
Papillary thyroid carcinoma 0.000271442 1 0 BeFree
Islet Cell Tumor 0.000271442 1 0 BeFree
Carcinoma, Small Cell 0.000271442 1 0 BeFree
Schinzel-Giedion syndrome 0.000271442 1 0 BeFree
Chronic colitis 0.000271442 1 0 BeFree
Cancer of Head and Neck 0.000271442 1 0 BeFree
Anal carcinoma 0.000271442 1 0 BeFree
Caries (morphologic abnormality) 0.000271442 1 0 BeFree
Carcinoid tumor no ICD-O subtype 0.000271442 1 0 BeFree
Adenocarcinoma of colon 0.000271442 1 0 BeFree
Multiple malignancy 0.000271442 1 0 BeFree
Intestinal Cancer 0.000271442 1 0 BeFree
Polyp of duodenum 0.000271442 1 0 BeFree
Carcinoma of anal margin 0.000271442 1 0 BeFree
Leukemogenesis 0.000271442 1 0 BeFree
invasive cancer 0.000271442 1 0 BeFree
Stage IV Colorectal Cancer 0.000271442 1 0 BeFree
Carcinoma of lung 0.000271442 1 0 BeFree
Carcinoma of bladder 0.000271442 1 0 BeFree
Malignant neoplasm of kidney 0.000271442 1 0 BeFree
Poorly differentiated carcinoma 0.000271442 1 0 BeFree
Medullary Neoplasms 0.000271442 1 0 BeFree
Adenomatous polyp of colon 0.000271442 1 0 BeFree
Helicobacter pylori infection 0.000271442 1 0 BeFree
Adenoviral infections 0.000271442 1 0 BeFree
Pancreatic carcinoma resectable 0.000271442 1 0 BeFree
Arteriovenous Malformations, Cerebral 0.000271442 1 0 BeFree
ovarian neoplasm 0.000271442 1 0 BeFree
precancerous lesions 0.000271442 1 0 BeFree
Colorectal cancer metastatic 0.000271442 1 0 BeFree
Polyp of small intestine 0.000271442 1 0 BeFree
Primary Carcinoma 0.000271442 1 0 BeFree
Renal carcinoma 0.000271442 1 0 BeFree
Primary Lesion 0.000271442 1 0 BeFree
Skin Carcinogenesis 0.000271442 1 0 BeFree
Prostatic Hypertrophy 0.000271442 1 0 BeFree
Congenital vascular anomaly 0.000271442 1 0 BeFree
Pancreatic islet cell tumors 0.000271442 1 0 BeFree
Clear-cell metastatic renal cell carcinoma 0.000271442 1 0 BeFree
Stage IV Colorectal Cancer AJCC v7 0.000271442 1 0 BeFree
Gastrointestinal Hamartoma 0.000271442 1 0 BeFree
FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) 0.000271442 1 0 BeFree
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