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This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Jun 2013]
[中文简述(自动翻译):] 该基因是溶质载体蛋白基因的线粒体载体亚科的成员。的该基因用作选通孔从细胞质到从线粒体基质进入细胞质的线粒体基质和ATP易位ADP产物。该蛋白质在permability转换孔复合物(PTPC),其调节线粒体的产品,诱导细胞凋亡的释放的功能有关。人类基因组中包含该基因的几种非转录假基因。 [由RefSeq的,2013年6月提供]
SLC25A6基因(以及对应的蛋白质)的细胞分布位置:
SLC25A6基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
HIV Infections | 0.001357209 | 5 | 0 | BeFree |
Cardiomyopathy, Dilated | 0.000271442 | 1 | 0 | BeFree |
Enterovirus Infections | 0.000271442 | 1 | 0 | BeFree |
Glioblastoma | 0.000271442 | 1 | 0 | BeFree |
Developmental delay (disorder) | 0.000271442 | 1 | 0 | BeFree |
Mitochondrial Diseases | 0.000271442 | 1 | 0 | BeFree |
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