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The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
[中文简述(自动翻译):]  由该基因编码的膜蛋白是叶酸的转运,并参与叶酸的细胞内浓度的调节。三个转录变异体的编码不同亚型也发现了这种基因。[由RefSeq的,2011年3月提供]
SLC19A1基因(以及对应的蛋白质)的细胞分布位置:
SLC19A1基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Down Syndrome | 0.134906897 | 12 | 5 | BeFree_CTD_human_GAD_LHGDN |
Precursor Cell Lymphoblastic Leukemia Lymphoma | 0.132082858 | 12 | 5 | BeFree_CTD_human_GAD_LHGDN |
Cleft Lip | 0.125005506 | 4 | 0 | BeFree_CTD_human_GAD |
Cleft Palate | 0.124734064 | 3 | 0 | CTD_human_GAD |
Colorectal Neoplasms | 0.12272435 | 2 | 0 | CTD_human_LHGDN |
Adenoma | 0.120271442 | 2 | 5 | BeFree_CTD_human |
Autistic Disorder | 0.120271442 | 2 | 2 | BeFree_CTD_human |
Bladder Neoplasm | 0.12 | 1 | 0 | CTD_human |
Colonic Neoplasms | 0.12 | 1 | 0 | CTD_human |
nervous system disorder | 0.12 | 1 | 0 | CTD_human |
Adverse reaction to drug | 0.12 | 1 | 0 | CTD_human |
Chronic Kidney Insufficiency | 0.08 | 1 | 0 | RGD |
Neural Tube Defects | 0.031486052 | 11 | 0 | GAD_LHGDN |
Rheumatoid Arthritis | 0.019998279 | 12 | 4 | BeFree_GAD_LHGDN |
Malignant neoplasm of lung | 0.00973957 | 4 | 0 | BeFree_GAD |
Spina Bifida | 0.008001298 | 4 | 2 | BeFree_GAD_LHGDN |
Methotrexate poisoning | 0.007101096 | 3 | 0 | GAD |
Osteosarcoma | 0.00680591 | 7 | 0 | BeFree_LHGDN |
Lymphoma | 0.005634266 | 4 | 0 | BeFree_GAD_LHGDN |
Malignant neoplasm of breast | 0.005624334 | 12 | 10 | BeFree_GAD |
leukemia | 0.005362824 | 3 | 0 | BeFree_GAD_LHGDN |
Malignant neoplasm of urinary bladder | 0.005276948 | 3 | 0 | BeFree_GAD |
Cerebrovascular accident | 0.005276948 | 4 | 3 | BeFree_GAD |
Lung Neoplasms | 0.005091382 | 2 | 0 | GAD_LHGDN |
Lymphoma, Non-Hodgkin | 0.005005506 | 3 | 5 | BeFree_GAD |
Malignant neoplasm of prostate | 0.004734064 | 2 | 0 | GAD |
Colorectal Cancer | 0.003724241 | 6 | 0 | BeFree_GAD |
Non-Small Cell Lung Carcinoma | 0.003452799 | 5 | 0 | BeFree_GAD |
Breast Carcinoma | 0.003257302 | 12 | 10 | BeFree |
Coronary heart disease | 0.003181358 | 4 | 4 | BeFree_GAD |
Congenital Heart Defects | 0.003181358 | 4 | 0 | BeFree_GAD |
Malignant neoplasm of stomach | 0.003181358 | 3 | 0 | BeFree_GAD |
Hyperhomocysteinemia | 0.003181358 | 4 | 3 | BeFree_GAD |
Abruptio Placentae | 0.00272435 | 1 | 0 | LHGDN |
Thrombosis | 0.00272435 | 1 | 0 | LHGDN |
Acute lymphocytic leukemia | 0.002714419 | 10 | 5 | BeFree |
Adenocarcinoma | 0.002638474 | 2 | 0 | BeFree_GAD |
Folic Acid Deficiency | 0.002638474 | 2 | 0 | BeFree_GAD |
Meningomyelocele | 0.002638474 | 1 | 0 | BeFree_GAD |
Coronary Artery Disease | 0.002638474 | 2 | 3 | BeFree_GAD |
Malignant tumor of colon | 0.002367032 | 1 | 0 | GAD |
Brain Ischemia | 0.002367032 | 1 | 0 | GAD |
Ulcerative Colitis | 0.002367032 | 1 | 0 | GAD |
Crohn Disease | 0.002367032 | 1 | 0 | GAD |
Drug Allergy | 0.002367032 | 1 | 0 | GAD |
Heart Septal Defects | 0.002367032 | 1 | 0 | GAD |
Hyperparathyroidism, Secondary | 0.002367032 | 1 | 0 | GAD |
Female infertility | 0.002367032 | 1 | 0 | GAD |
Insulin Resistance | 0.002367032 | 1 | 1 | GAD |
Chronic Obstructive Airway Disease | 0.002367032 | 1 | 0 | GAD |
Lymphoma, Follicular | 0.002367032 | 1 | 0 | GAD |
Pregnancy Complications, Cardiovascular | 0.002367032 | 1 | 0 | GAD |
Stomach Neoplasms | 0.002367032 | 1 | 0 | GAD |
B-Cell Lymphomas | 0.002367032 | 1 | 0 | GAD |
Diffuse Large B-Cell Lymphoma | 0.002367032 | 1 | 0 | GAD |
T-Cell Lymphoma | 0.002367032 | 1 | 0 | GAD |
Premature Birth | 0.002367032 | 1 | 0 | GAD |
Aortic Aneurysm, Abdominal | 0.002367032 | 1 | 0 | GAD |
Oxidative Stress | 0.002367032 | 1 | 0 | GAD |
Congenital omphalocele | 0.002367032 | 1 | 0 | GAD |
Venous Thromboembolism | 0.002367032 | 1 | 0 | GAD |
Colorectal Carcinoma | 0.001085767 | 4 | 0 | BeFree |
Leukemia, Lymphocytic, Acute, L1 | 0.001085767 | 4 | 3 | BeFree |
Osteosarcoma of bone | 0.000814326 | 3 | 0 | BeFree |
Stomach Carcinoma | 0.000814326 | 3 | 0 | BeFree |
Homocysteinemia | 0.000814326 | 3 | 3 | BeFree |
Neuroblastoma | 0.000542884 | 2 | 0 | BeFree |
Retinoblastoma | 0.000542884 | 2 | 5 | BeFree |
Carcinoma of bladder | 0.000542884 | 2 | 0 | BeFree |
Central neuroblastoma | 0.000542884 | 2 | 0 | BeFree |
Cleft Lip with or without Cleft Palate | 0.000542884 | 2 | 0 | BeFree |
Squamous cell carcinoma of the head and neck | 0.000542884 | 2 | 2 | BeFree |
Precursor B-cell lymphoblastic leukemia | 0.000542884 | 2 | 2 | BeFree |
Malignant neoplasm of larynx | 0.000271442 | 1 | 0 | BeFree |
Squamous cell carcinoma | 0.000271442 | 1 | 0 | BeFree |
Intracranial Aneurysm | 0.000271442 | 1 | 0 | BeFree |
Cerebral Infarction | 0.000271442 | 1 | 0 | BeFree |
Esophagitis | 0.000271442 | 1 | 2 | BeFree |
Hypertensive disease | 0.000271442 | 1 | 0 | BeFree |
Leukopenia | 0.000271442 | 1 | 0 | BeFree |
Neoplasm Metastasis | 0.000271442 | 1 | 0 | BeFree |
Nephroblastoma | 0.000271442 | 1 | 0 | BeFree |
Stomatitis | 0.000271442 | 1 | 2 | BeFree |
Lymphoma, Large-Cell, Follicular | 0.000271442 | 1 | 5 | BeFree |
Spina Bifida Occulta | 0.000271442 | 1 | 0 | BeFree |
Tumor Progression | 0.000271442 | 1 | 0 | BeFree |
Metastatic osteosarcoma | 0.000271442 | 1 | 0 | BeFree |
Cancer of Head and Neck | 0.000271442 | 1 | 0 | BeFree |
Primary central nervous system lymphoma | 0.000271442 | 1 | 0 | BeFree |
Impaired cognition | 0.000271442 | 1 | 0 | BeFree |
Hematologic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of esophagus | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of larynx | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
extranodal lymphoma | 0.000271442 | 1 | 0 | BeFree |
Adult Acute Lymphocytic Leukemia | 0.000271442 | 1 | 0 | BeFree |
Brain Infarction | 0.000271442 | 1 | 0 | BeFree |
Acute GVH disease | 0.000271442 | 1 | 0 | BeFree |
Ischemic stroke | 0.000271442 | 1 | 0 | BeFree |
Colorectal cancer metastatic | 0.000271442 | 1 | 0 | BeFree |
Adenoma of large intestine | 0.000271442 | 1 | 0 | BeFree |
Childhood Leukemia | 0.000271442 | 1 | 0 | BeFree |
Maternal Fever | 0.000271442 | 1 | 0 | BeFree |
Ischemic Cerebrovascular Accident | 0.000271442 | 1 | 0 | BeFree |
Juvenile arthritis | 0.000271442 | 1 | 3 | BeFree |
Juvenile rheumatoid arthritis | 0.000271442 | 1 | 3 | BeFree |
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