SGCA(sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

17q21
基因染色体位置图

基因简述

基因简述

This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

[中文简述(自动翻译):]  该基因编码肌营养不良蛋白糖蛋白复合物（DGC），这是对肌纤维膜的稳定性和肌动蛋白细胞骨架的细胞外基质的连接临界的一个组成部分。其表达被认为只限于横纹肌。突变在该基因的结果在类型2D常染色体隐性肢带型肌营养不良症。已发现该基因编码不同亚型的多个抄本变形。 [由RefSeq的，2008年10月提供]

OMIM数据库中对SGCA基因的介绍     Wikipedia数据库中对SGCA基因的介绍

基因序列

基因序列

SGCA基因的碱基序列：[NCBI]

基因突变

基因突变

SGCA基因的碱基突变：           显示全部snp
rs1046329       rs2586476       rs2586477       rs2586478       rs2696290       rs2696292       rs2696293       rs8075369       rs12451943       rs28625650       rs36107109       rs67004890       rs73987436       rs74470554       rs76235917       rs79284438       rs112307751       rs112486992       rs112555099       rs112764774       rs113461264       rs138734924       rs139001717       rs139351874       rs140324461       rs140331153       rs141256127       rs142442633       rs142727180       rs143604012       rs144192798       rs144326926       rs144829518       rs145676626       rs145906333       rs146576503       rs147342150      
rs148798182       rs148908024       rs149793680       rs150724634       rs151305009       rs181050621       rs182037811       rs182960623       rs184193668       rs184348662       rs185621631       rs187247342       rs187546495       rs188527234       rs190083296       rs190506263       rs190749419       rs200189699       rs201384458       rs201568182       rs201954784       rs202159116       rs368912332       rs529321873       rs530838745       rs531804928       rs533768162       rs535642322       rs535704048       rs536305091       rs537461193       rs537868035       rs538450247       rs538859796       rs540079398       rs540366160       rs540409478       rs542756099       rs542817482       rs542822857       rs543929498       rs545246309       rs545257890       rs546792468       rs547137630       rs547383976       rs549148476       rs549310161       rs549718935       rs549891823       rs550842553       rs551100374       rs552098815       rs553418424       rs553706109       rs553896773       rs553938029       rs554437428       rs554913339       rs554950397       rs556486999       rs556532664       rs556652374       rs557298829       rs557594242       rs558837900       rs560244930       rs560261283       rs560343826       rs562768303       rs562840918       rs563061919       rs564196925       rs564439132       rs564450242       rs564456784       rs565288141       rs567389875       rs568592361       rs569474745       rs569625947       rs571826352       rs572784946       rs573184303       rs573807867       rs573930619       rs573994102       rs574932400       rs576605518       rs577635413       rs745545693       rs745811350       rs746390681       rs746566047       rs746575666       rs747800992       rs748401364       rs748900446       rs749781722       rs749799902       rs750331940       rs750880932       rs752839782       rs752858213       rs754025496       rs756385022       rs756405185       rs758422383       rs759406401       rs760238343       rs761646794       rs762248646       rs762761081       rs762771752       rs764347808       rs765151470       rs765348604       rs766368084       rs767570029       rs767590288       rs769615019       rs769702957       rs770315778       rs770703831       rs771425133       rs771533829       rs772037672       rs773123421       rs773211747       rs774413738       rs775524806       rs776378396       rs777442599       rs778104801       rs778123289       rs778203237       rs779572684       rs780910730       rs781345155       rs2293533       rs2412299       rs2586471       rs2696297       rs9911548       rs12939159       rs16948742       rs28933693       rs55711850       rs59944537       rs60407644       rs61627360       rs66503819       rs71146969       rs71353621       rs72840643       rs73334777       rs73334779       rs73987434       rs75145501       rs79410682       rs111430486       rs111636387       rs112401162       rs112500642       rs114653108       rs115380008       rs115864048       rs116913189       rs117672945       rs118134751       rs137852621       rs138191456       rs138945081       rs140261054       rs140477549       rs140629621       rs141953249       rs142537375       rs142681846       rs143315002       rs145697858       rs146026504       rs147145924       rs147723267       rs147739328       rs148132791       rs148431038       rs149296410       rs150403591       rs180689583       rs181197612       rs184021050       rs184716603       rs185145130       rs186669379       rs187436528       rs188376742       rs189947364       rs190222006       rs191162824       rs191944135       rs193194777       rs199527818       rs199804045       rs199804735       rs199902950       rs200075504       rs200137051       rs200478178       rs200626376       rs200973744       rs201094873       rs201937845       rs367733438       rs368082336       rs368405019       rs369340251       rs370370150       rs370819630       rs371433770       rs371445704       rs371675217       rs372175922       rs372497416       rs373770886       rs373949696       rs374973969       rs375504165       rs376629082       rs377006294       rs377120535       rs398123098       rs527959287       rs528129990       rs529188229       rs529322015       rs530494919       rs531607706       rs533470336       rs533579654       rs533770766       rs535054464       rs535350861       rs536244332       rs536879203       rs537437685       rs538043721       rs539315496       rs539354167       rs539515085       rs539899170       rs539905537       rs540051953       rs540292629       rs540434314       rs541831246       rs542301870       rs542864100       rs544048517       rs546465078       rs546959034       rs547080329       rs548572054       rs549342488       rs549494788       rs550378485       rs550901659       rs550972267       rs551765351       rs553541687       rs553618895       rs554636603       rs554946707       rs555088959       rs556716977       rs557332265       rs557589479       rs558692465       rs560029157       rs560047096       rs563836663       rs565069721       rs566647417       rs566905540       rs566948776       rs569162014       rs569234502       rs569744194       rs570272086       rs570435420       rs570716848       rs570942577       rs571892675       rs572359946       rs573657824       rs573669204       rs573747062       rs573792379       rs574942530       rs574961464       rs575518404       rs576413728       rs577610508       rs745447270       rs745997466       rs746116353       rs746675022       rs747404648       rs747828491       rs747984529       rs748232461       rs748694967       rs748856279       rs749097695       rs749182388       rs749205073       rs749454797       rs749555493       rs749873696       rs749990267       rs750582302       rs751086043       rs751466815       rs752271672       rs752288242       rs752640127       rs753180048       rs753896716       rs754599566       rs754840688       rs754950929       rs754969463       rs755329398       rs755416307       rs756091736       rs756110158       rs756679424       rs757198700       rs757371081       rs757888349       rs758457189       rs758637637       rs758647756       rs759284746       rs759446037       rs759624003       rs759692350       rs760528436       rs761265198       rs761732772       rs761749068       rs762122257       rs762366356       rs762704751       rs763279422       rs763462790       rs764017448       rs764589225       rs764831663       rs765231848       rs765710068       rs766190767       rs766209304       rs766400853       rs766610494       rs766671542       rs766946752       rs767726021       rs767928766       rs768450963       rs768814872       rs769123700       rs769272010       rs769685812       rs769778891       rs770106306       rs770516658       rs770840649       rs770986247       rs771150580       rs771236695       rs771571944       rs772233387       rs772395882       rs772581198       rs772635734       rs773161308       rs773599406       rs773659174       rs774012999       rs774107033       rs774299871       rs774478786       rs774505441       rs774714920       rs775137020       rs775361706       rs775818041       rs775818669       rs775978141       rs776195527       rs776411719       rs776498843       rs776923555       rs777028657       rs777061914       rs777898534       rs777931940       rs778476146       rs779249845       rs779439298       rs780299372       rs780478384       rs1801190       rs1801191       rs2440124       rs2586479       rs2696286       rs2696287       rs2696288       rs2696289       rs2696294       rs2696295       rs2696296       rs3986433       rs11868160       rs11870423       rs16948744       rs35130237       rs35495899       rs35972733       rs56273576       rs60300808       rs61481658       rs73334793       rs73334795       rs73987439       rs77472740       rs112317169       rs112757126       rs112838180       rs113107132       rs113182656       rs113535280       rs113826038       rs113885623       rs114123806       rs115738022       rs116461461       rs116638508       rs116931748       rs137852623       rs138019537       rs138254713       rs138800403       rs139454982       rs140077564       rs140437918       rs141198630       rs141302696       rs141892209       rs142169382       rs142231484       rs143365858       rs143551687       rs143570936       rs143663300       rs143962150       rs144392726       rs144932150       rs145087775       rs145252144       rs146924667       rs147162020       rs148269842       rs148373921       rs148572611       rs148960833       rs149487996       rs150383400       rs150524482       rs150771690       rs182535883       rs182587544       rs183964744       rs185412634       rs186835316       rs189244564       rs189746381       rs190245746       rs190894395       rs192198247       rs193052653       rs199518562       rs199590719       rs199791980       rs199810179       rs200098340       rs200166783       rs200318091       rs200753576       rs200932512       rs200945974       rs201116286       rs201120276       rs201131924       rs201363900       rs201486782       rs201518390       rs201625981       rs201860673       rs367690233       rs367913636       rs368243053       rs368388538       rs368438774       rs368522117       rs369071464       rs369359375       rs369385261       rs369986635       rs371049397       rs371240005       rs371382065       rs371673068       rs372018946       rs372046855       rs372210292       rs372521553       rs372772903       rs373312721       rs373603128       rs374054759       rs374090814       rs374989747       rs375006608       rs375282807       rs375692868       rs376216559       rs376296830       rs376376394       rs376589369       rs376706935       rs377571255       rs377689717       rs387907298       rs527985789       rs528147836       rs528200488       rs528305800       rs529740649       rs530380742       rs530646204       rs530720511       rs532079651       rs532126154       rs532164844       rs532695517       rs535071060       rs535244758       rs537632734       rs538696245       rs538716110       rs539068757       rs540254057       rs541628736       rs541786593       rs542404148       rs543425025       rs544279803       rs544415988       rs545380272       rs546616047       rs547946960       rs547948789       rs547985289       rs549492266       rs550647495       rs551873219       rs552299305       rs555132312       rs555208148       rs556088617       rs556111440       rs556148302       rs556257950       rs556348647       rs557247436       rs557406842       rs557631989       rs558473298       rs559037337       rs559041055       rs559084851       rs561564714       rs561712694       rs563410677       rs565224729       rs566160814       rs566753460       rs567956814       rs567999025       rs568554303       rs568609723       rs569873415       rs570136558       rs572522406       rs572645859       rs572724109       rs573155826       rs574376340       rs577470269       rs745716686       rs745983208       rs746073282       rs746298469       rs746412103       rs746698767       rs746842113       rs746950050       rs747187312       rs747684069       rs747746408       rs748104722       rs748132102       rs748423372       rs748562980       rs748652852       rs748936034       rs749278299       rs749376128       rs749517670       rs749544769       rs749660438       rs749965562       rs750016201       rs750104371       rs750297310       rs750403766       rs750594985       rs750636856       rs750795695       rs750844090       rs751138418       rs751156929       rs751393023       rs751408157       rs751466306       rs751545380       rs752037390       rs752057472       rs752418232       rs752477093       rs752695991       rs753187816       rs753277911       rs753386774       rs753639843       rs753650776       rs753658307       rs753750830       rs753972912       rs753990343       rs754687036       rs754703769       rs754827696       rs754962516       rs755510141       rs755619226       rs755825098       rs756137267       rs756590750       rs756750438       rs756912039       rs756925443       rs756966125       rs757226910       rs757481230       rs758103053       rs758384359       rs758472374       rs758813493       rs758956473       rs758998049       rs759159622       rs759387828       rs759841180       rs759931078       rs760363758       rs760590168       rs760608643       rs760989961       rs761188156       rs761255036       rs761353909       rs761835321       rs761952510       rs762700889       rs763372958       rs763446303       rs763694408       rs763704395       rs763781902       rs763883513       rs763986788       rs764099922       rs764186209       rs764188161       rs764545490       rs764788649       rs764804960       rs765026954       rs765312750       rs765429436       rs765633764       rs765864199       rs766219704       rs766749734       rs766855169       rs766947313       rs767086617       rs767125816       rs767530246       rs768024803       rs768186538       rs768466052       rs768643970       rs768722155       rs768849469       rs769084027       rs769454942       rs769688229       rs769706480       rs769951787       rs770468219       rs771206406       rs771317654       rs771485989       rs771832102       rs771876078       rs772397834       rs772505692       rs772516696       rs773107290       rs773224488       rs773830869       rs773985328       rs774673678       rs774960107       rs775275347       rs775773189       rs776214016       rs776452550       rs776514178       rs776674917       rs776844526       rs777162824       rs777523838       rs778289213       rs778379427       rs778559408       rs778794746       rs779816288       rs779818045       rs779834721       rs780086613       rs780178776       rs780200261       rs780264754       rs780288099       rs780564461       rs780956236       rs780981677       rs781311989       rs781380620      

基因表达

基因表达

SGCA基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TGTCCACATCACCTACCAC
59
AGGCTGTGACCTCAATGAC
60
ATTCTGGACCAGCACTGAC
60
GAGGATGAAGTCAGGGCTG
60
TCATTCTGGACCAGCACTG
60
GAGGATGAAGTCAGGGCTG
60
TCTTGCTACGACACCTTGG
60
GACCATCTGGATGTCGGAG
60
ATACCAAGCCGAGTTCCTG
60
GACCATCTGGATGTCGGAG
60
CTGTCCACATCACCTACCA
59
ATTGTAGGCTGTGACCTGG
59
GGGTATACATTAAGGTGGATAAGTC
59
ATCCACCAAGAAGTCACGG
60
TGACTTCTTGGTGGATGCT
59
GACCATCTGGATGTCGGAG
60
CTTTGTGCACACCTTGGAC
60
ATTGTAGGCTGTGACCGAC
60
TCTTCTGGACTCCTCTCCTC
60
ATTGTAGGCTGTGACCGAC
60

转录因子

转录因子

      尚未收录相关数据

基因本体信息

SGCA基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

SGCA基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0016012
D6RAA4(UniProtKB)
IEA
GO:0005509
E9PCT8(UniProtKB)
IEA
GO:0016012
E9PCT8(UniProtKB)
IEA
GO:0016012
H0Y8T1(UniProtKB)
IEA
GO:0016021
H0Y8T1(UniProtKB)
IEA
GO:0016012
H7C5V0(UniProtKB)
IEA
GO:0005509
Q16586(UniProtKB)
IEA
GO:0005515
Q16586(UniProtKB)
IPI
GO:0005515
Q16586(UniProtKB)
IPI
GO:0005737
Q16586(UniProtKB)
IEA
GO:0005856
Q16586(UniProtKB)
IEA
GO:0005911
Q16586(UniProtKB)
IEA
GO:0006936
Q16586(UniProtKB)
TAS
GO:0007517
Q16586(UniProtKB)
TAS
GO:0016010
Q16586(UniProtKB)
TAS
GO:0016012
Q16586(UniProtKB)
IBA
GO:0016021
Q16586(UniProtKB)
IEA
GO:0042383
Q16586(UniProtKB)
IEA
GO:0045121
Q16586(UniProtKB)
IEA
GO:0061024
Q16586(UniProtKB)
IBA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控SGCA基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Alpha-Sarcoglycanopathies 0.323800186 18 3 BeFree_MGD_ORPHANET_UNIPROT
Sarcoglycanopathies 0.120271442 1 0 BeFree_CTD_human
Peripheral Neuropathy 0.12 1 0 CTD_human
Muscular Dystrophies, Limb-Girdle 0.006795978 16 1 BeFree_LHGDN
Muscular Dystrophy 0.004885954 18 0 BeFree
Respiratory Insufficiency 0.00272435 1 0 LHGDN
Severe childhood autosomal recessive muscular dystrophy 0.002714419 10 0 BeFree
Myopathy 0.001357209 5 0 BeFree
Muscle Weakness 0.000814326 3 0 BeFree
Becker Muscular Dystrophy 0.000814326 3 0 BeFree
Muscular Dystrophy, Duchenne 0.000542884 2 0 BeFree
Paresis 0.000542884 2 0 BeFree
Protein Deficiency 0.000542884 2 0 BeFree
Chronic Neutrophilic Leukemia 0.000271442 1 0 BeFree
Scoliosis, unspecified 0.000271442 1 0 BeFree
Rhabdomyosarcoma, Embryonal 0.000271442 1 0 BeFree
Severe autosomal recessive muscular dystrophy of childhood - North African type (disorder) 0.000271442 1 0 BeFree
Congenital scoliosis 0.000271442 1 0 BeFree
Acquired scoliosis 0.000271442 1 0 BeFree
FRAGILE X TREMOR/ATAXIA SYNDROME 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

没有相关文献

基因相关服务

基因相关服务

基因评论

基因评论

我要说两句
热门评论
还没有评论，赶快来抢沙发吧。

登陆

用户名:

密    码:

联系方式

山东省济南市 高新区 崇华路359号 三庆世纪财富中心C1115室

电话： 0531-88819269

E-mail: product@genelibs.com

微信公众号

扫一扫右方二维码，关注微信订阅号，实时查看信息，关注医学生物学动态。

版权所有 © 2016.Genelibs 济南弘晖生物技术有限公司 鲁ICP备13024435号-2