SFRP2(secreted frizzled-related protein 2) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

4q31.3
基因染色体位置图

基因简述

基因简述

This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  这个基因编码包含富含半胱氨酸的结构域同源的卷曲蛋白的推定的Wnt结合位点的SFRP家族的一个成员。的SFR P充当Wnt信号传导的可溶性调节剂。该基因的甲基化是结肠直肠癌的存在的潜在标记物。 [由RefSeq的，2008年7月提供]

OMIM数据库中对SFRP2基因的介绍     Wikipedia数据库中对SFRP2基因的介绍

基因序列

基因序列

SFRP2基因的碱基序列：[NCBI]

基因突变

基因突变

SFRP2基因的碱基突变：           显示全部snp
rs2405201       rs2405202       rs2405203       rs2405204       rs2405205       rs3039554       rs3810765       rs4075422       rs4076441       rs4077965       rs4145339       rs4643790       rs6535952       rs6853435       rs6853522       rs6853529       rs9799574       rs9997258       rs10009567       rs10031991       rs10537931       rs11099911       rs11549707       rs11933560       rs11937424       rs12648078       rs13140722       rs17030428       rs17030432       rs17030434       rs17030437       rs33935312       rs34176108       rs58582545       rs62325138       rs62325139       rs71620273      
rs74482074       rs74549610       rs74636475       rs74895329       rs74935258       rs76074060       rs76180108       rs77221794       rs77226137       rs77403151       rs77675213       rs78004612       rs78031334       rs78176516       rs78183709       rs78502616       rs78694482       rs78745456       rs78897284       rs79071507       rs79251246       rs79360581       rs79590832       rs79844222       rs111422265       rs111605237       rs112745055       rs112975560       rs113100080       rs113149806       rs113265903       rs113737172       rs114345132       rs114535404       rs114815881       rs114971533       rs116235863       rs116376341       rs117505354       rs138046969       rs138858118       rs138983900       rs139333413       rs140062669       rs140068876       rs140103463       rs141029820       rs142040319       rs142242428       rs142800086       rs143588179       rs143701440       rs143831532       rs144480119       rs144496209       rs144586687       rs145057129       rs145111028       rs145387388       rs146047729       rs146054481       rs146081333       rs146367628       rs146847678       rs146960655       rs147057596       rs147561445       rs148091166       rs149213476       rs149325204       rs150066809       rs150588121       rs150904708       rs151143527       rs180759323       rs180928701       rs181365853       rs183193116       rs183234074       rs184125534       rs184182644       rs184253824       rs184382734       rs184904203       rs185642574       rs185758413       rs186107103       rs186206914       rs186764000       rs186887390       rs187039674       rs187522691       rs189039358       rs189204130       rs189380070       rs189431480       rs189759342       rs190281766       rs190572568       rs191087002       rs191841123       rs191961491       rs192265977       rs192763428       rs193141580       rs199551756       rs199574740       rs200140334       rs200306522       rs200416071       rs201194044       rs201360782       rs201375139       rs201496741       rs201939231       rs367648625       rs368864730       rs369095724       rs369290690       rs369336784       rs369573402       rs370056219       rs370321307       rs370947515       rs371557028       rs371981299       rs372112598       rs372305008       rs372453250       rs373859519       rs374257060       rs374367957       rs374977998       rs375102628       rs376028620       rs376506469       rs376726694       rs377115096       rs377226693       rs527422707       rs527704612       rs528367042       rs528916536       rs528916788       rs529570911       rs529699833       rs529862927       rs529920099       rs529973327       rs530255761       rs531347806       rs531460096       rs532348726       rs532488989       rs532542812       rs532665227       rs533672415       rs533800119       rs534229867       rs534946610       rs535696843       rs535922914       rs535923929       rs536039525       rs536197603       rs537196247       rs537197055       rs537514784       rs537870385       rs538115297       rs538306843       rs538501615       rs538704114       rs539775673       rs540446496       rs540665441       rs541004158       rs541083903       rs541765175       rs542425871       rs542884865       rs543551938       rs543625090       rs543786680       rs544352681       rs544663975       rs544936588       rs545655666       rs546360010       rs546477029       rs546651894       rs546692575       rs546880909       rs547571397       rs547775763       rs547848450       rs547961093       rs547961809       rs548072686       rs549268506       rs549746367       rs549834854       rs550500715       rs550533064       rs550694146       rs550858513       rs551064932       rs551799638       rs551958860       rs552149899       rs552258278       rs552583483       rs552817303       rs553805856       rs554130422       rs554133044       rs554171681       rs554397533       rs554432240       rs554434224       rs555370514       rs555578710       rs555919053       rs555923170       rs556787764       rs556819971       rs557357728       rs557786916       rs558101652       rs558129803       rs558166699       rs558844962       rs559226092       rs559360607       rs559440037       rs560480764       rs560520464       rs560582539       rs561069269       rs561618144       rs562458405       rs562694873       rs562986187       rs563121525       rs563324936       rs564065128       rs564171692       rs564224096       rs564550445       rs565216959       rs565519020       rs566138955       rs566208700       rs566216504       rs566358859       rs567406935       rs567559918       rs568103122       rs568589695       rs568634063       rs568714178       rs568745998       rs568751579       rs568910695       rs569276115       rs569368233       rs569682949       rs570187286       rs570395250       rs570482758       rs571105933       rs571548938       rs572004683       rs572569633       rs572684685       rs573196460       rs573232957       rs573778059       rs573892780       rs574389389       rs574426844       rs574908569       rs574985460       rs574987082       rs575096800       rs576149897       rs576161014       rs576321523       rs576360555       rs576462577       rs576704698       rs577372814       rs745495443       rs745728569       rs745780901       rs746191282       rs746223049       rs746452136       rs746645168       rs746895350       rs747207310       rs747444264       rs747505062       rs747851787       rs747981958       rs748007328       rs748185168       rs748210745       rs748645726       rs748918381       rs749026873       rs749150736       rs749380731       rs749568139       rs749773062       rs750157608       rs750580738       rs750639404       rs750708205       rs750894692       rs751262135       rs751304614       rs751372172       rs751451705       rs751527740       rs751722152       rs751866721       rs752091964       rs752198476       rs752591339       rs752649413       rs752832663       rs752945147       rs753164723       rs753354046       rs753458519       rs753743362       rs754080507       rs754081413       rs754638637       rs754658364       rs755100730       rs755129928       rs755324538       rs755799375       rs755873100       rs756001605       rs756222613       rs756408557       rs757918334       rs758528622       rs758736793       rs758904161       rs758949251       rs759006172       rs759366315       rs759496190       rs759548421       rs759789403       rs759948174       rs760130726       rs760233107       rs760558817       rs760702591       rs761122354       rs761122719       rs761355765       rs761563727       rs762008694       rs762120819       rs762231333       rs762280165       rs762467203       rs762937267       rs763124627       rs763257920       rs763381743       rs763657211       rs763890885       rs764531946       rs764627420       rs764725894       rs765162489       rs765503696       rs765558863       rs765668271       rs766298515       rs766388547       rs766692048       rs766826304       rs767318221       rs767413214       rs767611732       rs767751716       rs768299995       rs768693726       rs768944571       rs768984513       rs769038342       rs769276642       rs769796878       rs770048924       rs770359121       rs770398211       rs770485715       rs770504683       rs770735868       rs771360002       rs771539103       rs771576600       rs771814142       rs772075948       rs772223712       rs772407898       rs772454059       rs772645804       rs773382763       rs773515619       rs773710868       rs773765944       rs774006240       rs774857018       rs774907975       rs775112152       rs775356830       rs775477124       rs775708674       rs776095519       rs776175695       rs776535023       rs777049412       rs777067149       rs777193551       rs777214656       rs777406941       rs777418633       rs777446620       rs777535378       rs777771497       rs778153340       rs778291441       rs778386528       rs778647547       rs778665160       rs779169377       rs779979352       rs780386874       rs780433893       rs780841026       rs781000602       rs781288672       rs781436435      

基因表达

基因表达

SFRP2基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CTAGACGAGACCATCCAGC
59
ATACCTTTGGAGCTTCCTCG
60
CTAGACGAGACCATCCAGC
59
TACCTTTGGAGCTTCCTCG
59
CCTAGACGAGACCATCCAG
59
TACCTTTGGAGCTTCCTCG
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

SFRP2基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

SFRP2基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001569
Q96HF1(UniProtKB)
ISS
GO:0001968
Q96HF1(UniProtKB)
ISS
GO:0002063
Q96HF1(UniProtKB)
IEA
GO:0003151
Q96HF1(UniProtKB)
IMP
GO:0003214
Q96HF1(UniProtKB)
IMP
GO:0004930
Q96HF1(UniProtKB)
IBA
GO:0005178
Q96HF1(UniProtKB)
ISS
GO:0005615
Q96HF1(UniProtKB)
ISS
GO:0005615
Q96HF1(UniProtKB)
IDA
GO:0007186
Q96HF1(UniProtKB)
IEA
GO:0007267
Q96HF1(UniProtKB)
ISS
GO:0007584
Q96HF1(UniProtKB)
IEA
GO:0008284
Q96HF1(UniProtKB)
IDA
GO:0008285
Q96HF1(UniProtKB)
IMP
GO:0008285
Q96HF1(UniProtKB)
IDA
GO:0008584
Q96HF1(UniProtKB)
IEA
GO:0010629
Q96HF1(UniProtKB)
ISS
GO:0010667
Q96HF1(UniProtKB)
IEA
GO:0010719
Q96HF1(UniProtKB)
IDA
GO:0010950
Q96HF1(UniProtKB)
IEA
GO:0016021
Q96HF1(UniProtKB)
IBA
GO:0017147
Q96HF1(UniProtKB)
IBA
GO:0017147
Q96HF1(UniProtKB)
NAS
GO:0030178
Q96HF1(UniProtKB)
IDA
GO:0030178
Q96HF1(UniProtKB)
NAS
GO:0030199
Q96HF1(UniProtKB)
IEA
GO:0030307
Q96HF1(UniProtKB)
ISS
GO:0030308
Q96HF1(UniProtKB)
IDA
GO:0030336
Q96HF1(UniProtKB)
ISS
GO:0030514
Q96HF1(UniProtKB)
IEA
GO:0031012
Q96HF1(UniProtKB)
ISS
GO:0031668
Q96HF1(UniProtKB)
IEA
GO:0033138
Q96HF1(UniProtKB)
ISS
GO:0033630
Q96HF1(UniProtKB)
ISS
GO:0035413
Q96HF1(UniProtKB)
IEA
GO:0035567
Q96HF1(UniProtKB)
IBA
GO:0036342
Q96HF1(UniProtKB)
IEA
GO:0042493
Q96HF1(UniProtKB)
IEA
GO:0042662
Q96HF1(UniProtKB)
IEA
GO:0042733
Q96HF1(UniProtKB)
IEA
GO:0042813
Q96HF1(UniProtKB)
IBA
GO:0043065
Q96HF1(UniProtKB)
IMP
GO:0043154
Q96HF1(UniProtKB)
IEA
GO:0043508
Q96HF1(UniProtKB)
IEA
GO:0045600
Q96HF1(UniProtKB)
IDA
GO:0045669
Q96HF1(UniProtKB)
IEA
GO:0045766
Q96HF1(UniProtKB)
ISS
GO:0045892
Q96HF1(UniProtKB)
IDA
GO:0045944
Q96HF1(UniProtKB)
ISS
GO:0048018
Q96HF1(UniProtKB)
ISS
GO:0048546
Q96HF1(UniProtKB)
IEA
GO:0050680
Q96HF1(UniProtKB)
IDA
GO:0050732
Q96HF1(UniProtKB)
ISS
GO:0060028
Q96HF1(UniProtKB)
IEA
GO:0060349
Q96HF1(UniProtKB)
IEA
GO:0061056
Q96HF1(UniProtKB)
ISS
GO:0061133
Q96HF1(UniProtKB)
IEA
GO:0061185
Q96HF1(UniProtKB)
ISS
GO:0071425
Q96HF1(UniProtKB)
ISS
GO:0071481
Q96HF1(UniProtKB)
IEA
GO:0090090
Q96HF1(UniProtKB)
IDA
GO:0090179
Q96HF1(UniProtKB)
IEA
GO:0090244
Q96HF1(UniProtKB)
IEA
GO:0090263
Q96HF1(UniProtKB)
ISS
GO:1902042
Q96HF1(UniProtKB)
IEA
GO:1902230
Q96HF1(UniProtKB)
ISS
GO:1904338
Q96HF1(UniProtKB)
IEA
GO:1904693
Q96HF1(UniProtKB)
IEA
GO:2000035
Q96HF1(UniProtKB)
ISS
GO:2000041
Q96HF1(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控SFRP2基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Colorectal Neoplasms 0.131168843 7 0 BeFree_CTD_human_LHGDN
Renal Cell Carcinoma 0.123538676 3 0 BeFree_CTD_human_LHGDN
Inflammatory Bowel Diseases 0.120542884 2 0 BeFree_CTD_human
Mammary Neoplasms 0.120542884 2 0 BeFree_CTD_human
Myocardial Infarction 0.08 0 0 RGD
Myocardial Reperfusion Injury 0.08 0 0 RGD
Colorectal Cancer 0.008262808 15 0 BeFree_GAD
Adenoma 0.003810118 4 0 BeFree_LHGDN
Colorectal Carcinoma 0.003528744 13 0 BeFree
Bladder Neoplasm 0.002995792 1 0 BeFree_LHGDN
Squamous cell carcinoma 0.002995792 2 0 BeFree_LHGDN
Liver neoplasms 0.00272435 1 0 LHGDN
Pancreatic Neoplasm 0.00272435 1 0 LHGDN
Pituitary Neoplasms 0.00272435 1 0 LHGDN
ovarian neoplasm 0.00272435 1 0 LHGDN
Albuminuria 0.002367032 1 1 GAD
Asthma 0.002367032 1 0 GAD
Left Ventricular Hypertrophy 0.002367032 1 0 GAD
Carcinogenesis 0.002171535 8 0 BeFree
Malignant neoplasm of breast 0.001085767 4 0 BeFree
Breast Carcinoma 0.001085767 4 0 BeFree
Leukemia, Myelocytic, Acute 0.000814326 3 0 BeFree
Hyperplastic Polyp 0.000814326 3 0 BeFree
Adenocarcinoma 0.000542884 2 0 BeFree
Malignant tumor of cervix 0.000542884 2 0 BeFree
Malignant neoplasm of stomach 0.000542884 2 0 BeFree
Multiple Myeloma 0.000542884 2 0 BeFree
Retinitis Pigmentosa 0.000542884 2 0 BeFree
Cicatrix, Hypertrophic 0.000542884 2 0 BeFree
Adenomatous Polyps 0.000542884 2 0 BeFree
Cervix carcinoma 0.000542884 2 0 BeFree
Stomach Carcinoma 0.000542884 2 0 BeFree
Adenoma of large intestine 0.000542884 2 0 BeFree
Bone Diseases 0.000271442 1 0 BeFree
Ulcerative Colitis 0.000271442 1 0 BeFree
Gastrointestinal Neoplasms 0.000271442 1 0 BeFree
Glioblastoma 0.000271442 1 0 BeFree
Keloid 0.000271442 1 0 BeFree
Chronic Lymphocytic Leukemia 0.000271442 1 0 BeFree
Medulloblastoma 0.000271442 1 0 BeFree
Parathyroid Neoplasms 0.000271442 1 0 BeFree
polyps 0.000271442 1 0 BeFree
Rectal polyp 0.000271442 1 0 BeFree
Oral Cavity Carcinoma 0.000271442 1 0 BeFree
Tumor Progression 0.000271442 1 0 BeFree
Lip and Oral Cavity Carcinoma 0.000271442 1 0 BeFree
Cervical Adenocarcinoma 0.000271442 1 0 BeFree
Solid tumour 0.000271442 1 0 BeFree
Adenocarcinoma in Situ 0.000271442 1 0 BeFree
Malignant neoplasm of prostate 0.000271442 1 0 BeFree
Malignant Glioma 0.000271442 1 0 BeFree
Prostate carcinoma 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lymph node 0.000271442 1 0 BeFree
Malignant neoplasm of kidney 0.000271442 1 0 BeFree
precancerous lesions 0.000271442 1 0 BeFree
High-Grade Prostatic Intraepithelial Neoplasia 0.000271442 1 0 BeFree
Basaloid squamous cell carcinoma 0.000271442 1 0 BeFree
Esophageal Basaloid Carcinoma 0.000271442 1 0 BeFree
Renal carcinoma 0.000271442 1 0 BeFree
Cancer Cell Growth 0.000271442 1 0 BeFree
Non-Neoplastic Disorder 0.000271442 1 0 BeFree
Intracranial glioma 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

没有相关文献

基因相关服务

基因相关服务

基因评论

基因评论

我要说两句
热门评论
还没有评论，赶快来抢沙发吧。

登陆

用户名:

密    码:

联系方式

山东省济南市 高新区 崇华路359号 三庆世纪财富中心C1115室

电话： 0531-88819269

E-mail: product@genelibs.com

微信公众号

扫一扫右方二维码，关注微信订阅号，实时查看信息，关注医学生物学动态。

版权所有 © 2016.Genelibs 济南弘晖生物技术有限公司 鲁ICP备13024435号-2