SAT1(spermidine/spermine N1-acetyltransferase 1) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

基因染色体位置

基因染色体位置

Xp22.1

基因简述

基因简述

The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009]

[中文简述(自动翻译):]  由该基因编码的蛋白质属于乙酰家庭，并且是在多胺代谢的分解代谢途径中的限速酶。它催化亚精胺和精胺的乙酰化，并参与多胺的细胞内浓度和它们的运输进出细胞的调节。这种基因缺陷与毛囊角化症椤decalvans（KFSD）有关。或者拼接的成绩单也发现了这种基因。[由RefSeq的，2009年09月提供]

OMIM数据库中对SAT1基因的介绍     Wikipedia数据库中对SAT1基因的介绍

基因序列

基因序列

SAT1基因的碱基序列：[NCBI]

基因突变

基因突变

SAT1基因的碱基突变：           显示全部snp
rs781479672       rs781157221       rs781220543       rs780634321       rs780689420       rs780177290       rs779150835       rs779242223       rs777638546       rs776979200       rs777493282       rs775768486       rs776784626       rs774942866       rs773639549       rs773982728       rs772825361       rs771791252       rs769555216       rs770757258       rs769407721       rs768149528       rs766741127       rs767058466       rs766687812       rs765638178       rs765781283       rs765578698       rs764239848       rs762423178       rs762503016       rs761860804       rs759812284       rs760906221       rs758893829       rs758406520       rs757834957      
rs757176838       rs757525953       rs756342715       rs754972725       rs754587266       rs754254001       rs752149094       rs754145954       rs751858477       rs751658235       rs751238388       rs750695278       rs750872348       rs749095747       rs749219213       rs749056797       rs748119306       rs748212946       rs748006451       rs746629550       rs556451893       rs745994814       rs528053662       rs373499605       rs374606645       rs370945465       rs369343665       rs201091896       rs191789974       rs191760162       rs188735170       rs187419083       rs186009531       rs181173157       rs148483557       rs147672674       rs145618629       rs144320087       rs142757578       rs140890109       rs113693085       rs112405732       rs113541391       rs80286169       rs112104496       rs76924627       rs77572990       rs76711072       rs75415964       rs73625179       rs73625178       rs11413410       rs41305193       rs6627976       rs6526344       rs6526343       rs2855499       rs2532616       rs2532618       rs2071030       rs928933       rs11404       rs781758000       rs781732282       rs781022086       rs780108068       rs780059226       rs779830922       rs779096573       rs779093106       rs778863754       rs778776707       rs778484367       rs778288207       rs778237393       rs777335609       rs777157648       rs777012184       rs776868417       rs776017309       rs775760722       rs775653572       rs775545603       rs775318195       rs774822224       rs774590584       rs774012990       rs773960231       rs773463503       rs771632138       rs771451420       rs771411539       rs771326772       rs771145782       rs770974016       rs770641195       rs770420326       rs770248013       rs770053467       rs769137466       rs769068150       rs768921302       rs768382151       rs768027618       rs767671088       rs767432320       rs767248787       rs766643919       rs766012632       rs765052504       rs764988660       rs764882680       rs764862163       rs764050893       rs763907600       rs763333869       rs763064333       rs762247036       rs761989827       rs761878508       rs761659596       rs761372150       rs760664631       rs760481236       rs760416815       rs759396263       rs759250758       rs758575147       rs758520675       rs757975430       rs757920478       rs757743977       rs757435207       rs756702253       rs756652932       rs756503777       rs755630308       rs755576994       rs755181810       rs754997244       rs754863854       rs754393850       rs753558693       rs753371942       rs753134609       rs752565067       rs752488427       rs752469765       rs751859106       rs751722615       rs751600110       rs751358268       rs750793198       rs750034262       rs749742537       rs749496374       rs749355547       rs748575574       rs747542931       rs747491672       rs747365906       rs747031398       rs746811448       rs746576123       rs745891782       rs745565799       rs745485198       rs375352696       rs374212275       rs374107682       rs372403117       rs368684242       rs368001685       rs200440143       rs193127399       rs192765099       rs191762819       rs191054876       rs190250383       rs189949920       rs189004882       rs185859650       rs185772892       rs184684390       rs182899168       rs182373471       rs180942326       rs149732167       rs148814497       rs145980431       rs145594541       rs145472400       rs139915283       rs139763071       rs138635490       rs113759625       rs113458958       rs113294310       rs113025395       rs112080346       rs41311469       rs17551556       rs13440941       rs13440940       rs12846646       rs12838869       rs12832660       rs11550721       rs6629746       rs6526342       rs5925934       rs3764885       rs3764884       rs2855497       rs2855496       rs2532621       rs1960264       rs928932       rs928931       rs7929      

基因表达

基因表达

SAT1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ACTCCGGAAGGTTACAGTC
59
CAATCCACGGGTCATAGGT
59
GAAGAATCTAAGCCAGGTTGC
59
GATGGATGGTTCATTCCATTCTG
60
GAAGAATCTAAGCCAGGTTGC
59
GATGGATGGTTCATTCCATTCTG
60
GAAGAATCTAAGCCAGGTTGC
59
ATGGATGGTTCATTCCATTCTG
59
GACTGCAGTGACATACTGC
59
AACAATGCTGTGTCCTTCC
58
ATGAATACATGGATGGGCG
58
AAACCAACAATGCTGTGTC
57
CGACTGCAGTGACATACTG
58
AACAATGCTGTGTCCTTCC
58
AGAAGTAGTGTCGGCTGTG
60
CCAAGTTCTCAGTAACTTCGG
59
TAAATTCGTGATCCGCCCA
60
TTAGCCAGCTCCTTGATCAG
60
ATGTAAGAAGTAGTGTCGGC
58
TTCTCAGTAACTTCGGCCT
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

SAT1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

SAT1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0004145
A6NJE6(UniProtKB)
IEA
GO:0004145
A6NM56(UniProtKB)
IEA
GO:0004145
E9PD37(UniProtKB)
IEA
GO:0001525
P21673(UniProtKB)
IEP
GO:0004145
P21673(UniProtKB)
TAS
GO:0004145
P21673(UniProtKB)
TAS
GO:0005515
P21673(UniProtKB)
IPI
GO:0005515
P21673(UniProtKB)
IPI
GO:0005515
P21673(UniProtKB)
IPI
GO:0005515
P21673(UniProtKB)
IPI
GO:0005515
P21673(UniProtKB)
IPI
GO:0005622
P21673(UniProtKB)
IDA
GO:0005829
P21673(UniProtKB)
TAS
GO:0005829
P21673(UniProtKB)
TAS
GO:0006596
P21673(UniProtKB)
TAS
GO:0009447
P21673(UniProtKB)
IEA
GO:0042127
P21673(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控SAT1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Obesity 0.122171535 9 2 BeFree_CTD_human
Keratosis pilaris decalvans 0.120814326 3 0 BeFree_ORPHANET
IGA Glomerulonephritis 0.12 1 0 CTD_human
Dermatitis, Allergic Contact 0.12 1 0 CTD_human
Keratosis Follicularis Spinulosa Decalvans, X-Linked 0.12 0 0 CTD_human
Colorectal Neoplasms 0.005720142 3 0 BeFree_LHGDN
Malignant neoplasm of lung 0.003181358 3 0 BeFree_GAD
Colonic Neoplasms 0.002995792 2 0 BeFree_LHGDN
Schizophrenia 0.002909916 2 0 BeFree_GAD
Malignant neoplasm of ovary 0.002909916 3 0 BeFree_GAD
Tick-Borne Encephalitis 0.00272435 1 0 LHGDN
Venezuelan equine encephalomyelitis 0.00272435 1 0 LHGDN
Keratosis Follicularis 0.00272435 1 0 LHGDN
Lung Neoplasms 0.00272435 1 0 LHGDN
Reperfusion Injury 0.00272435 1 0 LHGDN
ovarian neoplasm 0.00272435 1 0 LHGDN
Mammary Neoplasms 0.00272435 1 0 LHGDN
Malignant neoplasm of breast 0.001085767 4 0 BeFree
Non-Small Cell Lung Carcinoma 0.001085767 4 0 BeFree
Colorectal Carcinoma 0.001085767 4 0 BeFree
Carcinogenesis 0.001085767 4 0 BeFree
Breast Carcinoma 0.001085767 4 0 BeFree
Carcinoma of lung 0.001085767 4 0 BeFree
Colorectal Cancer 0.001085767 4 0 BeFree
Anxiety Disorders 0.000814326 3 0 BeFree
Diabetes Mellitus, Non-Insulin-Dependent 0.000814326 3 0 BeFree
Ovarian Carcinoma 0.000814326 3 0 BeFree
Colon Carcinoma 0.000814326 3 0 BeFree
Rheumatoid Arthritis 0.000542884 2 0 BeFree
Bipolar Disorder 0.000542884 2 0 BeFree
Malignant tumor of colon 0.000542884 2 0 BeFree
Depressive disorder 0.000542884 2 0 BeFree
Diarrhea 0.000542884 2 0 BeFree
Liver neoplasms 0.000542884 2 0 BeFree
melanoma 0.000542884 2 0 BeFree
Tuberculosis 0.000542884 2 0 BeFree
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Metabolic Syndrome X 0.000542884 2 0 BeFree
Epithelial ovarian cancer 0.000542884 2 0 BeFree
Liver carcinoma 0.000542884 2 0 BeFree
Adenoma 0.000271442 1 0 BeFree
Arteriosclerosis 0.000271442 1 0 BeFree
Atherosclerosis 0.000271442 1 0 BeFree
Mental disorders 0.000271442 1 1 BeFree
Brain Neoplasms 0.000271442 1 0 BeFree
Rectal Carcinoma 0.000271442 1 0 BeFree
Ulcerative Colitis 0.000271442 1 0 BeFree
Mental Depression 0.000271442 1 0 BeFree
Heart failure 0.000271442 1 0 BeFree
Congestive heart failure 0.000271442 1 0 BeFree
Hyperoxaluria 0.000271442 1 0 BeFree
Ischemia 0.000271442 1 0 BeFree
Leukemia, Plasma Cell 0.000271442 1 0 BeFree
Lipodystrophy 0.000271442 1 0 BeFree
Lymphoma 0.000271442 1 0 BeFree
Malignant neoplasm of stomach 0.000271442 1 0 BeFree
Multiple Myeloma 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Tuberculosis, Pulmonary 0.000271442 1 0 BeFree
Unipolar Depression 0.000271442 1 0 BeFree
Urinary tract infection 0.000271442 1 0 BeFree
Small cell carcinoma of lung 0.000271442 1 0 BeFree
Diastrophic dysplasia 0.000271442 1 0 BeFree
Disease due to Parvoviridae 0.000271442 1 0 BeFree
Mood Disorders 0.000271442 1 0 BeFree
Squamous cell carcinoma of mouth 0.000271442 1 0 BeFree
Prostate carcinoma 0.000271442 1 0 BeFree
Stomach Carcinoma 0.000271442 1 0 BeFree
Carcinoma of bladder 0.000271442 1 0 BeFree
psychological distress 0.000271442 1 0 BeFree
Renal ischaemia 0.000271442 1 0 BeFree
Major Depressive Disorder 0.000271442 1 0 BeFree
Xenograft Model 0.000271442 1 0 BeFree
Depression and Suicide 0.000271442 1 0 BeFree
Glioblastoma Multiforme 0.000271442 1 0 BeFree
DOSAGE-SENSITIVE SEX REVERSAL 0.000271442 1 0 BeFree
Coronary Artery Disease 0.000271442 1 0 BeFree

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