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Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  组蛋白乙酰化起着在真核基因表达的调控中起关键作用。组蛋白乙酰化和去乙酰化是由多亚基复合催化。由该基因编码的蛋白是组蛋白脱乙酰复杂,其中包括SIN3,SAP18,HDAC1,HDAC2,RbAp46,RbAp48,和其它多肽的组分。这种复杂的是活跃在脱乙酰核心组八聚体,但在不活跃乙酰化组蛋白核小体。该基因的假基因位于[由RefSeq的,2008年7月提供] 3号染色体
SAP30基因(以及对应的蛋白质)的细胞分布位置:
SAP30基因的本体(GO)信息:
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