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This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  该基因编码对RSK(核糖体S6激酶)家族丝氨酸/苏氨酸激酶的成员。这种激酶包含2不相同激酶催化结构域和磷酸化多种底物,包括CREB1和c-fos。该基因的备选的转录剪接变体已被观察到,但没有被完全表征。 [由RefSeq的,2008年7月提供]
RPS6KA4基因(以及对应的蛋白质)的细胞分布位置:
RPS6KA4基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Primary biliary cirrhosis | 0.12 | 1 | 1 | GWASCAT |
| Rheumatoid Arthritis | 0.002638474 | 2 | 0 | BeFree_GAD |
| Leprosy | 0.002367032 | 1 | 1 | GAD |
| Biliary cirrhosis | 0.002367032 | 1 | 1 | GAD |
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