RPL22(ribosomal protein L22) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

1p36.31
基因染色体位置图

基因简述

基因简述

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  核糖体，催化蛋白质合成的细胞器，由一个小40S亚基和60S大亚基。一起这些亚基组成的4 RNA种类和大约80结构不同的蛋白质。这个基因编码细胞质核糖体蛋白，它是60S亚基的一个组成部分。该蛋白属于L22E家族核糖体的蛋白质。其起始甲硫氨酸残基是翻译后去除。该蛋白质可以特异性结合于1和2的小鼠蛋白已被证明能够结合到肝素Epstein-Barr病毒编码的RNA（埃伯斯）。成绩单变种利用替代polyA信号存在。作为典型编码核糖体蛋白的基因，有该基因通过基因组分散的多个经处理的假基因。它以前认为，这种基因被映射到3q26，它被融合于急性髓性白血病1（AML1）基因位于在一些治疗相关的骨髓增生异常综合征的患者21q22 3; 21易位;然而，这些融合实际上涉及位于3q26核糖体蛋白质L22假基因，并且该基因实际上映射到1p36.3-p36.2。 [由RefSeq的，2008年7月提供]

OMIM数据库中对RPL22基因的介绍     Wikipedia数据库中对RPL22基因的介绍

基因序列

基因序列

RPL22基因的碱基序列：[NCBI]

基因突变

基因突变

RPL22基因的碱基突变：           显示全部snp
rs3581       rs10260       rs15593       rs1052013       rs1052014       rs1053194       rs2038153       rs2143367       rs2247392       rs2294712       rs2294713       rs2294714       rs2311383       rs2311384       rs2311385       rs2311386       rs3789519       rs3789520       rs3789521       rs3789522       rs3789523       rs3789524       rs3789525       rs3827723       rs4908863       rs6664444       rs6679697       rs6692191       rs7521209       rs10864428       rs11121449       rs11121478       rs11540941       rs11540943       rs11590960       rs11800316       rs12057813      
rs12065054       rs12067135       rs12116884       rs12404210       rs35835676       rs45596539       rs57314419       rs58275601       rs60086377       rs60388719       rs71568644       rs71629776       rs71629777       rs71629778       rs71629779       rs74312753       rs74366465       rs74804565       rs75128158       rs75289866       rs75452815       rs75540340       rs75677223       rs75809570       rs76008792       rs76076480       rs76133466       rs76372313       rs76448447       rs76504190       rs76968273       rs76993308       rs77329537       rs77523453       rs77728216       rs78000590       rs78059059       rs78090611       rs78896992       rs79099684       rs79566146       rs79757299       rs79951804       rs80024766       rs111344017       rs111451703       rs111487228       rs111653210       rs111749599       rs112509219       rs112877474       rs112914870       rs112945699       rs113019044       rs113446760       rs113792721       rs113815548       rs113831112       rs113869895       rs113910114       rs114106966       rs114250207       rs114300540       rs114353372       rs114389092       rs114462621       rs114514884       rs114556784       rs114664925       rs115017920       rs115308536       rs115323483       rs115358198       rs115443234       rs115515694       rs115626957       rs115731358       rs115803895       rs115859081       rs116037349       rs116401170       rs116428108       rs116613757       rs116645486       rs116735038       rs116826810       rs117730888       rs137950338       rs138002841       rs138031347       rs138368160       rs138414898       rs138420769       rs138462647       rs138810626       rs138912465       rs139163058       rs139576941       rs139971856       rs140554216       rs140570169       rs140622361       rs140950669       rs141368007       rs141494853       rs141584315       rs141894157       rs142135928       rs142313527       rs142785368       rs143062325       rs143313406       rs143408501       rs143425663       rs143523640       rs143537820       rs143628865       rs144337052       rs144513416       rs144560570       rs144642005       rs144673014       rs145199978       rs145208160       rs145290478       rs145325545       rs145743423       rs145746203       rs145812616       rs145851351       rs145926177       rs145945493       rs146401397       rs146600452       rs147040482       rs147190771       rs147194083       rs147632334       rs148189670       rs148292869       rs148344629       rs148433326       rs148485073       rs148625257       rs148911927       rs149008599       rs149265771       rs149429904       rs149538712       rs149793616       rs150249425       rs150725445       rs150771403       rs150777375       rs151035196       rs151248713       rs180815177       rs181083312       rs181294863       rs181716143       rs182002958       rs182233626       rs182586344       rs182792856       rs183167772       rs183169956       rs183430195       rs183430683       rs183484131       rs183679417       rs183749483       rs183935758       rs184272458       rs184565987       rs184800432       rs185090883       rs185231433       rs185393613       rs185657994       rs185716272       rs185837996       rs185956882       rs186383773       rs186778305       rs187143466       rs187155122       rs187605226       rs187750459       rs187984324       rs188048817       rs188435409       rs188534718       rs188591504       rs188751254       rs189099397       rs189466853       rs189583841       rs189584171       rs190116845       rs190127334       rs190302501       rs190417995       rs190962120       rs191215198       rs191247564       rs191258445       rs191624433       rs191783856       rs192062105       rs192110751       rs192312048       rs192746397       rs192832986       rs192867690       rs193123711       rs193216299       rs193273549       rs199837725       rs200076283       rs200101942       rs201655993       rs367585690       rs368828780       rs369611211       rs369642817       rs369645807       rs370106403       rs370979341       rs371429487       rs371683418       rs371686414       rs372120891       rs372152282       rs372422001       rs372619661       rs373069290       rs373796322       rs374024961       rs374367647       rs374470866       rs374898156       rs375115806       rs375858011       rs376004306       rs376674459       rs376743120       rs376913258       rs527252001       rs527765632       rs527829507       rs527852079       rs527989905       rs528349067       rs528363680       rs528412228       rs528427515       rs528434126       rs529133846       rs529168598       rs529672613       rs529796979       rs529859379       rs529885821       rs530013412       rs530312263       rs530312827       rs530682348       rs530874849       rs531303490       rs531309292       rs531787249       rs531820026       rs532025870       rs532095562       rs532309328       rs532667006       rs532690450       rs532864926       rs533346451       rs533376747       rs533441686       rs533444172       rs533504093       rs533516543       rs533648395       rs533867828       rs534028747       rs534360530       rs534505312       rs534796125       rs534796325       rs535113832       rs535218924       rs535576838       rs535957126       rs535968737       rs535979546       rs536155562       rs536167159       rs536193892       rs536240875       rs536549607       rs536681405       rs536923127       rs536985879       rs537153352       rs537415756       rs537554872       rs537752734       rs538011321       rs538529442       rs538548782       rs538560890       rs538803576       rs538935523       rs539015523       rs539030887       rs539152430       rs539525355       rs539934503       rs539960419       rs540072967       rs540125744       rs540144092       rs540162000       rs540477535       rs540936930       rs541059757       rs541124345       rs541143935       rs541261144       rs541687229       rs541811197       rs541911068       rs541918302       rs541948109       rs542445220       rs542775235       rs543065321       rs543080504       rs543165593       rs543545466       rs543887334       rs544025448       rs544042717       rs544305924       rs544484689       rs544734823       rs545478573       rs545486261       rs545540046       rs545571580       rs545623094       rs545645885       rs546134377       rs546173204       rs546185394       rs546451489       rs546451579       rs546955047       rs547418123       rs547471742       rs547656525       rs547662515       rs547704116       rs547822393       rs548085787       rs548141325       rs548201627       rs548391960       rs548433879       rs548481386       rs548820752       rs549016566       rs549539947       rs549646003       rs549801640       rs550137663       rs550200585       rs550278805       rs550383303       rs550404800       rs550587699       rs550588327       rs550943350       rs551010892       rs551066861       rs551431676       rs551543209       rs551990815       rs552049917       rs552137214       rs552200415       rs552379005       rs552461067       rs552996502       rs553269090       rs553539838       rs554217540       rs554274487       rs554641106       rs554704235       rs554990995       rs554994573       rs555057469       rs555312623       rs555605451       rs556049245       rs556371824       rs556604083       rs556724561       rs557574628       rs557721767       rs558299823       rs558365988       rs558374591       rs558463620       rs558597671       rs558774087       rs558782683       rs559277076       rs559367172       rs559369037       rs559431777       rs559454589       rs559504203       rs559582499       rs560489428       rs560602754       rs560711660       rs560725715       rs560896146       rs561325586       rs561396049       rs561522369       rs561624188       rs561653204       rs562119363       rs562613256       rs562747809       rs562978575       rs563116826       rs563139932       rs563203597       rs563470415       rs563936727       rs564001275       rs564075787       rs564159870       rs564318140       rs564716899       rs564885504       rs565004691       rs565268244       rs565343524       rs565507949       rs565954229       rs566120397       rs566132652       rs566255939       rs566567861       rs566958773       rs567200329       rs567249879       rs567283239       rs567389356       rs567599174       rs567851807       rs567979844       rs568001525       rs568108111       rs568120510       rs568245507       rs568653475       rs568797504       rs569285472       rs569365504       rs569970116       rs570056198       rs570472054       rs570502784       rs570552199       rs570639389       rs571375720       rs571807179       rs572490277       rs572630017       rs572656849       rs572678004       rs572717760       rs573345024       rs573605279       rs573738135       rs573898181       rs574415878       rs574448828       rs574460301       rs574761136       rs574888109       rs575067231       rs575090283       rs575220351       rs575282924       rs575345575       rs575710961       rs575772512       rs575919221       rs575942277       rs576052051       rs576530128       rs576864614       rs577170489       rs577886814       rs578037341       rs578174619       rs745574419       rs746467070       rs746915278       rs747884052       rs748076544       rs748575507       rs749046728       rs749060131       rs749597857       rs749763074       rs749984698       rs750588118       rs750723507       rs750944709       rs751690139       rs752081077       rs753004590       rs753966592       rs754038770       rs754234933       rs754676340       rs754799980       rs755289033       rs755379091       rs755844948       rs756539363       rs756865761       rs757240358       rs758248955       rs758745546       rs758846226       rs759333777       rs759423831       rs759549802       rs760144293       rs760244396       rs760572251       rs760767852       rs761140121       rs761246474       rs762001013       rs762200622       rs762396571       rs762794415       rs763273312       rs764243959       rs764528989       rs765206560       rs765294490       rs765389147       rs765910053       rs766059536       rs766418714       rs767463484       rs767693583       rs768040071       rs768078095       rs768161804       rs768214471       rs768477350       rs768926960       rs768957960       rs769157446       rs769507341       rs769777834       rs769829497       rs771391799       rs771683309       rs772005076       rs772960921       rs773757515       rs773865799       rs774298678       rs774869596       rs775133086       rs775606193       rs775727908       rs776111950       rs776576619       rs776709767       rs777643906       rs777733738       rs778042326       rs778273300       rs778366883       rs779352419       rs779447954       rs779512704       rs779623219       rs779718870       rs780183704       rs780843327       rs781037531       rs781498088      

基因表达

基因表达

RPL22基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GAGAACAAGAGGCACTTGG
58
ATGATTCCATCTTCTACAGGGT
58
CGGTAGGAGGATAAAGAAGCA
59
CGGTTTGGCTCTATCAATAGG
58
GAGAACAAGAGGCACTTGG
58
TTTATCCTGGAGGTGGCAG
59
AAGATGGAATCATGGATGCTG
58
GTTCACTTTGATCCTTTCTTGC
58
AAGATCACCGTGACATCCG
59
TTGCTGTTAGCAACTACGC
58
AAGATGGAATCATGGATGCT
57
GTTCACTTTGATCCTTTCTTGC
58
CGGTAGGAGGATAAAGAAGCA
59
TCTGCTTTCCAGCTGATCC
59
GAGAACAAGAGGCACTTGG
58
CTTTATCCTGGAGGTGGCA
59
AGATGGAATCATGGATGCTG
57
GTTCACTTTGATCCTTTCTTGC
58
CAAGATCACCGTGACATCC
58
TTGCTGTTAGCAACTACGC
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

RPL22基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RPL22基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0003735
K7EJT5(UniProtKB)
IEA
GO:0005840
K7EJT5(UniProtKB)
IEA
GO:0006412
K7EJT5(UniProtKB)
IEA
GO:0003735
K7EKS7(UniProtKB)
IEA
GO:0005840
K7EKS7(UniProtKB)
IEA
GO:0006412
K7EKS7(UniProtKB)
IEA
GO:0003735
K7ELC4(UniProtKB)
IEA
GO:0005840
K7ELC4(UniProtKB)
IEA
GO:0006412
K7ELC4(UniProtKB)
IEA
GO:0003735
K7EMH1(UniProtKB)
IEA
GO:0005840
K7EMH1(UniProtKB)
IEA
GO:0006412
K7EMH1(UniProtKB)
IEA
GO:0003735
K7EP65(UniProtKB)
IEA
GO:0005840
K7EP65(UniProtKB)
IEA
GO:0006412
K7EP65(UniProtKB)
IEA
GO:0003735
K7ERI7(UniProtKB)
IEA
GO:0005840
K7ERI7(UniProtKB)
IEA
GO:0006412
K7ERI7(UniProtKB)
IEA
GO:0000184
P35268(UniProtKB)
TAS
GO:0002181
P35268(UniProtKB)
IBA
GO:0003723
P35268(UniProtKB)
TAS
GO:0003735
P35268(UniProtKB)
NAS
GO:0005515
P35268(UniProtKB)
IPI
GO:0005634
P35268(UniProtKB)
IDA
GO:0005737
P35268(UniProtKB)
IDA
GO:0005829
P35268(UniProtKB)
TAS
GO:0005829
P35268(UniProtKB)
TAS
GO:0005829
P35268(UniProtKB)
TAS
GO:0005829
P35268(UniProtKB)
TAS
GO:0005829
P35268(UniProtKB)
TAS
GO:0005829
P35268(UniProtKB)
TAS
GO:0005829
P35268(UniProtKB)
TAS
GO:0005829
P35268(UniProtKB)
TAS
GO:0005829
P35268(UniProtKB)
TAS
GO:0005829
P35268(UniProtKB)
TAS
GO:0005829
P35268(UniProtKB)
TAS
GO:0005829
P35268(UniProtKB)
TAS
GO:0005829
P35268(UniProtKB)
TAS
GO:0005829
P35268(UniProtKB)
TAS
GO:0005925
P35268(UniProtKB)
IDA
GO:0006364
P35268(UniProtKB)
TAS
GO:0006412
P35268(UniProtKB)
NAS
GO:0006413
P35268(UniProtKB)
TAS
GO:0006614
P35268(UniProtKB)
TAS
GO:0008201
P35268(UniProtKB)
IEA
GO:0019083
P35268(UniProtKB)
TAS
GO:0022625
P35268(UniProtKB)
IDA
GO:0030529
P35268(UniProtKB)
IDA
GO:0044822
P35268(UniProtKB)
IDA
GO:0044822
P35268(UniProtKB)
IDA
GO:0046632
P35268(UniProtKB)
IEA
GO:0070062
P35268(UniProtKB)
IDA
GO:0070062
P35268(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控RPL22基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Myelodysplasia 0.000542884 2 0 BeFree
Preleukemia 0.000542884 2 0 BeFree
Carcinogenesis 0.000542884 2 0 BeFree
Malignant neoplasm of endometrium 0.000271442 1 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
Endometrial Neoplasms 0.000271442 1 0 BeFree
leukemia 0.000271442 1 0 BeFree
Acute lymphocytic leukemia 0.000271442 1 0 BeFree
Lobar Pneumonia 0.000271442 1 0 BeFree
Streptococcal pneumonia 0.000271442 1 0 BeFree
Endometrial Carcinoma 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lymph node 0.000271442 1 0 BeFree
Thymic Lymphoma 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree
Uterine Corpus Cancer 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

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