RPE65基因详情-基因数据库-基因云馆

RPE65(retinal pigment epithelium-specific protein 65kDa)

基因简称(symbol)

RPE65 [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

LCA2|rd12|BCO3

基因家族代码(gene_family_id)

[HGNC] [GenScript]

omim代码

180069

entrez码

6121 [Vega]

vega基因码

OTTHUMG00000009208

ensembl基因码

ENSG00000116745 [Ensembl]

基因家族(gene family)

refseq数据库代号

NM_000329

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

01p31

同源基因名称(alias name)

retinol isomerase|all-trans-retinyl-palmitate hydrolase|retinoid isomerohydrolase|BCO family, member 3

基因名称批准使用时间(date_approved_reserved)

1993-10-04T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

2002-08-29T00:00:00Z

更新时间(date_modified)

2014-11-19T00:00:00Z

ucsc码

uc001dei.1

ena

U18991

ccds数据码

CCDS643

uniprot数据码

Q16518

pubmed代码

8340400

mgd码

MGI:98001

rgd码

RGD:621396

生命科学数据库(lsdb)

Mutations of the RPE65 Gene|http://www.retina-international.org/files/sci-news/rpe65mut.htm

更新时间(date modified)

2014-11-19T00:00:00Z

cosmic

RPE65

mirbase

基因曾用简称(prev symbol)

RP20

基因曾用名称(prev name)

retinal pigment epithelium-specific protein (65kD)

homeodb

cosmic

RPE65

snornabase

bioparadigms slc

orphanet

118376

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

3.1.1.64

中间纤维数据库

收起

1p31

This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):] 这个基因编码，是在位于视网膜色素上皮细胞，并涉及生产11-顺式视黄醛和视色素的再生的蛋白质。有两种形式的这种蛋白质，称为sRPE65可溶形式，并称为mRPE65一棕榈酰化，膜结合形式。 mRPE65作为棕榈捐助卵磷脂视黄醇酰基转移酶（LRAT）催化维生素A生色团再生过程的全反式视黄醇工序的酶。既mRPE65和sRPE65兼作调节蛋白，用比与这些分子扮演的11-顺式视黄醛合成的抑制的作用的浓度。在这种基因突变与莱伯先天性黑朦2型（LCA2）和色素性视网膜炎相关联。 [由RefSeq的，2008年7月提供]

OMIM数据库中对RPE65基因的介绍 Wikipedia数据库中对RPE65基因的介绍

RPE65基因的碱基序列：[NCBI]

RPE65基因的碱基突变：显示全部snp

rs382422 rs635213 rs932783 rs1555845 rs1555846 rs1555847 rs1886906 rs1925955 rs2012235 rs2038900 rs2038901 rs2148138 rs2182315 rs2274321 rs2277874 rs2419982 rs2477974 rs2986124 rs2986125 rs3118415 rs3118416 rs3118417 rs3118418 rs3118419 rs3118420 rs3118421 rs3118423 rs3118424 rs3118425 rs3118426 rs3118427 rs3118428 rs3125891 rs3125893 rs3125894 rs3125895 rs3125896

rs3125898 rs3125899 rs3125900 rs3125901 rs3125902 rs3125903 rs3125904 rs3125905 rs3125906 rs3125907 rs3125908 rs3125909 rs3790466 rs3790469 rs3790471 rs3790472 rs3790473 rs5774935 rs9436836 rs11209301 rs11269074 rs11581095 rs11799958 rs12030710 rs12046996 rs12058579 rs12074337 rs12077372 rs12083082 rs12124063 rs12138573 rs12145904 rs12408546 rs12564647 rs12759602 rs13375676 rs17130685 rs17130688 rs17130689 rs17130691 rs17130693 rs17130694 rs34194247 rs34627040 rs41287870 rs41406946 rs41463549 rs55818296 rs55988364 rs56021047 rs56085477 rs56113622 rs57229366 rs57911424 rs59257923 rs61751276 rs61751277 rs61751279 rs61751282 rs61752866 rs61752870 rs61752871 rs61752873 rs61752877 rs61752878 rs61752883 rs61752884 rs61752887 rs61752893 rs61752895 rs61752901 rs61752903 rs61752905 rs61752907 rs61752908 rs61771494 rs61771495 rs61771496 rs62636297 rs62636299 rs62636300 rs62636301 rs62637005 rs62637006 rs62637007 rs62642581 rs62642584 rs62646883 rs62653011 rs62653014 rs62653015 rs71071305 rs72674310 rs72674316 rs72674317 rs72926953 rs72926973 rs74081904 rs74081908 rs74081914 rs74081924 rs74081933 rs74081939 rs74081941 rs74084042 rs74084043 rs74742779 rs75303265 rs75509427 rs75711879 rs75886344 rs76446417 rs76582994 rs76971768 rs76989114 rs77084725 rs77155188 rs77544521 rs77569826 rs77585943 rs78017676 rs78507000 rs79061671 rs79134554 rs79440416 rs79468836 rs79716012 rs80108164 rs111240881 rs111518661 rs111811751 rs112015440 rs112094349 rs112157684 rs112349100 rs112481917 rs112593019 rs112632447 rs112794565 rs112886088 rs112982614 rs113044298 rs113081587 rs113329701 rs113334710 rs113452977 rs113568355 rs113769246 rs113799984 rs113838052 rs114177515 rs114256657 rs114379164 rs114444355 rs114698131 rs115687982 rs116062666 rs116338530 rs116387471 rs116523964 rs116540274 rs116946639 rs117178090 rs121917744 rs121917745 rs137978847 rs138018979 rs138113233 rs138146176 rs138151609 rs138206611 rs138415744 rs138761471 rs138835303 rs139436418 rs139640666 rs140066022 rs140267674 rs140432897 rs141077949 rs141324183 rs141527042 rs142052358 rs142092475 rs142626873 rs142728369 rs142768806 rs143056561 rs143435745 rs143578550 rs143601765 rs143638877 rs143783952 rs143818895 rs143929144 rs144204173 rs144337414 rs144612129 rs144673747 rs144693251 rs144709160 rs144965088 rs145012871 rs145318478 rs145393494 rs145494150 rs145829030 rs146357166 rs146578932 rs147206805 rs147665807 rs147893529 rs148361356 rs148533201 rs148540443 rs148859047 rs148859816 rs148973921 rs149006408 rs149299400 rs149353114 rs149449684 rs149672233 rs149767405 rs149916178 rs150037382 rs150082696 rs150260489 rs150353909 rs150407554 rs150774295 rs150821448 rs150832066 rs150875558 rs151119890 rs151169409 rs151316763 rs180775036 rs180830348 rs180894466 rs181033251 rs181052675 rs181098062 rs181464621 rs181479494 rs181677143 rs181793378 rs181914407 rs182232422 rs182466411 rs182670797 rs183057836 rs183068296 rs183089473 rs183122161 rs183576418 rs183726660 rs184166742 rs184193928 rs184239420 rs184329893 rs184881429 rs184906223 rs184913094 rs185049543 rs185500883 rs185585417 rs185734152 rs186445520 rs187134054 rs187198628 rs187365202 rs187745497 rs187909600 rs187916002 rs188148936 rs188244770 rs188270712 rs188455857 rs188493184 rs188681656 rs189266733 rs189540785 rs189844465 rs189876903 rs189893338 rs190055421 rs190063582 rs190455342 rs190487172 rs190500416 rs190542253 rs190761343 rs190785346 rs191006505 rs191220864 rs191297025 rs191463973 rs191798525 rs192083751 rs192321025 rs192340859 rs192418677 rs192622985 rs192859862 rs192907397 rs193084518 rs193217996 rs199529021 rs199570207 rs199683808 rs199824408 rs199937647 rs200384926 rs200570887 rs200661005 rs200890297 rs200950327 rs201009374 rs201062742 rs201075875 rs201116540 rs201245688 rs201379753 rs201587195 rs202144873 rs202185816 rs202186372 rs267598701 rs367983478 rs368088025 rs368345411 rs368381348 rs368533067 rs369089695 rs369124851 rs369142161 rs369274611 rs369335287 rs369523082 rs369751280 rs369772824 rs370004418 rs370076628 rs370270768 rs370553891 rs371106770 rs371379383 rs371503220 rs371586530 rs371690915 rs371783875 rs371841247 rs372059562 rs372132824 rs372270144 rs372273815 rs372293967 rs372310414 rs372620785 rs372810790 rs373274945 rs373407314 rs373547092 rs373652862 rs373834001 rs373882259 rs374025747 rs374114711 rs374162988 rs374360179 rs374912874 rs374992440 rs375272714 rs375357584 rs375358477 rs375399090 rs375611153 rs376046177 rs376062802 rs376173240 rs376333739 rs376418354 rs376628071 rs376723106 rs377152481 rs377208368 rs377663200 rs377762154 rs377763733 rs527481626 rs527553554 rs527672156 rs527709682 rs527740801 rs527898122 rs527902277 rs528109377 rs528147172 rs528268427 rs528307078 rs529447590 rs529484595 rs529707192 rs529881594 rs529971430 rs530061761 rs530238048 rs530286680 rs530823029 rs530957733 rs531391957 rs531791669 rs531829740 rs532132856 rs532159118 rs532310398 rs532359432 rs532387057 rs532414878 rs532421135 rs532423328 rs532603324 rs532767682 rs532814587 rs532884385 rs533636980 rs533723678 rs533761675 rs533780045 rs533797369 rs534170200 rs534379271 rs534546400 rs534582922 rs534622762 rs534661454 rs534707543 rs534780193 rs534901182 rs534966743 rs535002135 rs535095468 rs535284480 rs535320084 rs535475439 rs535633234 rs535734289 rs535884497 rs535922762 rs536017185 rs536073181 rs536234910 rs536319403 rs536501735 rs536631092 rs536664579 rs536666046 rs536859597 rs537276339 rs537314671 rs537644842 rs537676903 rs537681592 rs538106846 rs538269211 rs538307721 rs538318844 rs538344492 rs538470557 rs539075072 rs539205642 rs539253801 rs539291271 rs539448091 rs539667303 rs539668936 rs539706077 rs539837619 rs539959634 rs540009187 rs540093309 rs540295495 rs540655143 rs540671818 rs541262796 rs541295020 rs541465954 rs541504415 rs541546843 rs541680288 rs541682064 rs541718680 rs541812265 rs541963180 rs542035752 rs542251547 rs542288611 rs542314576 rs542637860 rs543498979 rs543593113 rs543680417 rs543716439 rs543842689 rs544058084 rs544065979 rs544098383 rs544102150 rs544343146 rs544492377 rs544619662 rs544763671 rs544942843 rs545652328 rs545654193 rs545691256 rs545788333 rs545790360 rs545828167 rs545954047 rs546014344 rs546019838 rs546051031 rs546090697 rs546103655 rs546259571 rs546436424 rs546438684 rs546961342 rs547217014 rs547318428 rs547355560 rs547374432 rs547517446 rs547628822 rs547686107 rs547897737 rs547918923 rs548080793 rs548206769 rs548327539 rs548434230 rs548508606 rs548537552 rs548720203 rs548810223 rs548843513 rs549388118 rs549427236 rs549629777 rs549714604 rs549944476 rs550075726 rs550112068 rs550188846 rs550226030 rs550272558 rs550375799 rs550422268 rs550585308 rs550810502 rs550847470 rs551504624 rs551680669 rs551847317 rs551968785 rs552078570 rs552194944 rs552226729 rs552248559 rs552261532 rs552287890 rs552469637 rs552506549 rs552608867 rs552840070 rs552904728 rs553021315 rs553086006 rs553184817 rs553196782 rs553224812 rs553264911 rs553332053 rs553443330 rs553632462 rs553821227 rs553946246 rs553992820 rs554287124 rs554682036 rs554717213 rs554816888 rs554953648 rs555491034 rs555645891 rs555683893 rs555975037 rs556040009 rs556194635 rs556279718 rs556360420 rs556397149 rs556633702 rs556791998 rs556991918 rs557078281 rs557217664 rs557287454 rs557992385 rs558231803 rs558266391 rs558268623 rs558440003 rs558632305 rs558639485 rs558667180 rs558786234 rs558869945 rs559077457 rs559268350 rs559449429 rs559544081 rs559636259 rs559678386 rs559826144 rs559975684 rs559980827 rs560016642 rs560029705 rs560104859 rs560702140 rs560857869 rs561028359 rs561089527 rs561166804 rs561417501 rs561436231 rs561451780 rs561482061 rs561687694 rs561700310 rs561910556 rs562037932 rs562468101 rs563031427 rs563147524 rs563243570 rs563301289 rs563386918 rs563436658 rs563438706 rs563475134 rs563606097 rs564208064 rs564567561 rs564898200 rs564988333 rs565505129 rs565565541 rs565867045 rs565968125 rs566019517 rs566218524 rs566689492 rs566725072 rs566833014 rs567220421 rs567413920 rs567464663 rs567487687 rs567602047 rs567616150 rs567624821 rs567652536 rs567691146 rs567925046 rs568020610 rs568201135 rs568326413 rs568388625 rs568680289 rs568717074 rs569314330 rs569518910 rs569566217 rs569640612 rs569847959 rs570083260 rs570243660 rs570518981 rs570604180 rs570676780 rs570717392 rs570876542 rs571076350 rs571111378 rs571152093 rs571165326 rs571468020 rs571490987 rs571595591 rs571637161 rs571637205 rs571651415 rs571671910 rs571838330 rs571986394 rs572051263 rs572113244 rs572427897 rs572602017 rs572912981 rs572964875 rs573105146 rs573168184 rs573201511 rs573241171 rs573336349 rs573567736 rs573576234 rs574113278 rs574476228 rs574585050 rs574667172 rs574703707 rs574839935 rs574890775 rs575192091 rs575205092 rs575318367 rs575358130 rs575519378 rs575603566 rs575952305 rs575958792 rs576513774 rs576805938 rs576979678 rs577159070 rs577193739 rs577335767 rs577363559 rs577380023 rs577417659 rs577543648 rs577580683 rs577675068 rs577927551 rs578074076 rs578171706 rs578174625 rs745338004 rs745528226 rs745631048 rs745691559 rs745750377 rs745869155 rs745959862 rs746032112 rs746156974 rs746172764 rs746302664 rs746427254 rs746506594 rs746546336 rs746615161 rs746665921 rs746668196 rs746758414 rs746904646 rs747033834 rs747036331 rs747122876 rs747174742 rs747322353 rs747393487 rs747569700 rs747669227 rs747824902 rs747866162 rs748053581 rs748096417 rs748142481 rs748178346 rs748206052 rs748413171 rs748456353 rs748546353 rs748612997 rs748803591 rs748853700 rs748951871 rs749113709 rs749242996 rs749273171 rs749464766 rs749641899 rs749757610 rs749922257 rs749942889 rs749996158 rs750044532 rs750099371 rs750221863 rs750452715 rs750484227 rs750724065 rs750750345 rs750890448 rs750892483 rs750943553 rs750954616 rs751054481 rs751107532 rs751514302 rs751608746 rs751747069 rs751845928 rs751860030 rs752013197 rs752013538 rs752014088 rs752058510 rs752177964 rs752527520 rs752528881 rs752534184 rs752712313 rs752810906 rs752875512 rs752990312 rs753094079 rs753147728 rs753148979 rs753257368 rs753540419 rs753656894 rs753727990 rs753762349 rs753823417 rs753954638 rs753956649 rs754039418 rs754228407 rs754363796 rs754467429 rs754533608 rs754849641 rs754918678 rs754941362 rs755080522 rs755390876 rs755416186 rs755524380 rs755545288 rs755771907 rs755805126 rs755926386 rs756066661 rs756125943 rs756160706 rs756209191 rs756319324 rs756370637 rs756508097 rs756514758 rs756701183 rs756785114 rs757139183 rs757198850 rs757456911 rs757538512 rs757653340 rs757673747 rs758083026 rs758084677 rs758139036 rs758178066 rs758264644 rs758284944 rs758321182 rs758419556 rs758427062 rs758478861 rs758550330 rs758577890 rs758825902 rs758861723 rs759019904 rs759083163 rs759168564 rs759403626 rs759518248 rs759621160 rs759690120 rs759724703 rs759837786 rs759868752 rs760028903 rs760099873 rs760264027 rs760427319 rs760746347 rs760916063 rs760922403 rs761099368 rs761227832 rs761253680 rs761284021 rs761471961 rs761589071 rs761594270 rs762063627 rs762116242 rs762184191 rs762186209 rs762303824 rs762360753 rs762554543 rs762601687 rs762755850 rs762755878 rs762775279 rs762809797 rs762977154 rs763125041 rs763256793 rs763317722 rs763419166 rs763437650 rs763463652 rs763510899 rs763536294 rs763658561 rs763660740 rs763751144 rs763820730 rs764089164 rs764160079 rs764189309 rs764216792 rs764221382 rs764381043 rs764463195 rs764476046 rs764576639 rs764589805 rs764797700 rs764813192 rs764888162 rs765125431 rs765187623 rs765234445 rs765466601 rs765578176 rs765691555 rs765844982 rs765937188 rs766034867 rs766433624 rs766511188 rs766606302 rs766786856 rs766848627 rs766880580 rs766996940 rs767125482 rs767212885 rs767478543 rs767528365 rs767599203 rs767645673 rs767754954 rs767832588 rs767876005 rs767931252 rs768172512 rs768336015 rs768445391 rs768447444 rs768448761 rs768450520 rs768710948 rs768864571 rs768915904 rs768965316 rs768968396 rs768970681 rs769275432 rs769440649 rs769548166 rs769814819 rs770044163 rs770402204 rs770514332 rs770561977 rs770565619 rs770615371 rs770672092 rs770760551 rs771043004 rs771095890 rs771159132 rs771240677 rs771297879 rs771443885 rs771504682 rs771863086 rs771869960 rs772290877 rs772329130 rs772427491 rs772587294 rs772709311 rs772814035 rs772821305 rs773042449 rs773358979 rs773557127 rs773589920 rs773612245 rs773899086 rs773933584 rs774130993 rs774306896 rs774309607 rs774624260 rs774650221 rs774677664 rs774730978 rs774764689 rs774823693 rs774896870 rs775020347 rs775031159 rs775139279 rs775194430 rs775260650 rs775260770 rs775474532 rs775602082 rs775867619 rs776087415 rs776229399 rs776250699 rs776272491 rs776327627 rs776380208 rs776433230 rs776435165 rs776612353 rs776756253 rs776910617 rs776985825 rs777035385 rs777070222 rs777207027 rs777211540 rs777430374 rs777432633 rs777461552 rs777483146 rs777646597 rs777794932 rs777841157 rs777879312 rs777966849 rs778231195 rs778323735 rs778422718 rs778562772 rs778730940 rs778732572 rs778768116 rs778912170 rs778922780 rs778971957 rs779095202 rs779185734 rs779361282 rs779480128 rs779487067 rs779865130 rs779941200 rs780061944 rs780187813 rs780247600 rs780286840 rs780321185 rs780323897 rs780341142 rs780625967 rs780898366 rs780930307 rs781070470 rs781104072 rs781193278 rs781323113 rs781343755 rs781363989 rs781416649 rs781416768 rs781460267 rs781733825

RPE65基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

CAATTCTGTGCAGTGACGA

59

GAGGAAACTCAAATGCTTGAC

58

TGCAATTCTGTGCAGTGAC

59

GGAAACTCAAATGCTTGACGA

60

AAGATGATGGTGTAGTTCTGAG

58

TGGCATTCAGAATCAGGAG

57

尚未收录相关数据

RPE65基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

RPE65基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0001523

Q16518(UniProtKB)

TAS

GO:0001786

Q16518(UniProtKB)

ISS

GO:0001895

Q16518(UniProtKB)

IMP

GO:0003407

Q16518(UniProtKB)

IEA

GO:0004744

Q16518(UniProtKB)

IEA

GO:0005783

Q16518(UniProtKB)

IEA

GO:0005886

Q16518(UniProtKB)

TAS

GO:0006776

Q16518(UniProtKB)

TAS

GO:0007468

Q16518(UniProtKB)

IEA

GO:0007601

Q16518(UniProtKB)

TAS

GO:0007623

Q16518(UniProtKB)

IEA

GO:0008286

Q16518(UniProtKB)

IEA

GO:0016020

Q16518(UniProtKB)

ISS

GO:0016702

Q16518(UniProtKB)

IEA

GO:0031090

Q16518(UniProtKB)

IEA

GO:0031210

Q16518(UniProtKB)

ISS

GO:0042572

Q16518(UniProtKB)

IEA

GO:0042574

Q16518(UniProtKB)

IEA

GO:0042574

Q16518(UniProtKB)

IEA

GO:0044297

Q16518(UniProtKB)

IEA

GO:0046872

Q16518(UniProtKB)

IEA

GO:0050908

Q16518(UniProtKB)

IMP

GO:0052884

Q16518(UniProtKB)

TAS

GO:0052885

Q16518(UniProtKB)

ISS

GO:0052885

Q16518(UniProtKB)

ISS

GO:0055114

Q16518(UniProtKB)

IEA

GO:0060042

Q16518(UniProtKB)

IEA

GO:0071257

Q16518(UniProtKB)

IEA

GO:1901612

Q16518(UniProtKB)

ISS

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控RPE65基因的相关microRNA：

hsa-miR-32 hsa-miR-335

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
LEBER CONGENITAL AMAUROSIS, TYPE II (disorder)	0.440271442	12	8	BeFree_CLINVAR_CTD_human_MGD_UNIPROT
Retinitis Pigmentosa	0.372711618	13	2	BeFree_CLINVAR_CTD_human_GAD_LHGDN_ORPHANET
Retinitis Pigmentosa 20	0.32	8	8	CLINVAR_MGD_UNIPROT
Leber Congenital Amaurosis	0.255743629	59	1	BeFree_CTD_human_ORPHANET
Blind Vision	0.140722847	9	0	CTD_human_GAD_LHGDN
Retinal Dystrophies	0.124885954	19	1	BeFree_CTD_human
Optic Atrophy, Hereditary, Leber	0.122638474	4	0	BeFree_CTD_human_GAD
Choroideremia	0.12	0	0	ORPHANET
Eye Diseases, Hereditary	0.12	1	0	CTD_human
Diabetes Mellitus, Experimental	0.08	1	0	RGD
Squamous cell carcinoma	0.012757768	47	0	BeFree
Carcinogenesis	0.010586233	39	0	BeFree
Ectodermal Dysplasia	0.007057489	26	0	BeFree
Retinal Degeneration	0.006981544	18	1	BeFree_GAD
Split-Hand/Foot Malformation	0.004885954	18	1	BeFree
Rudiger syndrome 1	0.004614512	17	0	BeFree
Hay-Wells syndrome	0.004614512	17	0	BeFree
Squamous cell carcinoma of the head and neck	0.003800186	14	0	BeFree
Neoplasm Metastasis	0.003528744	13	0	BeFree
Ectrodactyly	0.003528744	13	0	BeFree
Split hand foot deformity 1	0.003528744	13	0	BeFree
Retinal Diseases	0.003452799	5	0	BeFree_GAD
Adenocarcinoma	0.002985861	11	0	BeFree
Breast Carcinoma	0.002985861	11	1	BeFree
Cleft palate with cleft lip	0.002442977	9	0	BeFree
RAPP-HODGKIN SYNDROME	0.002442977	9	0	BeFree
Malignant neoplasm of breast	0.002171535	8	1	BeFree
Tumor Progression	0.001900093	7	0	BeFree
Amaurosis	0.001900093	7	1	BeFree
ADULT SYNDROME	0.001900093	7	0	BeFree
Congenital Abnormality	0.001628651	6	0	BeFree
Malignant neoplasm of prostate	0.001628651	6	0	BeFree
Prostate carcinoma	0.001628651	6	0	BeFree
Unspecified visual loss	0.001628651	6	3	BeFree
Malignant neoplasm of urinary bladder	0.001357209	5	0	BeFree
Non-Small Cell Lung Carcinoma	0.001357209	5	0	BeFree
Ovarian Carcinoma	0.001357209	5	1	BeFree
Lichen Planus, Oral	0.001357209	5	0	BeFree
Ankyloblepharon	0.001357209	5	0	BeFree
Carcinoma of bladder	0.001357209	5	0	BeFree
Retinal Dystrophy, Early Onset Severe	0.001357209	5	0	BeFree
Limb Deformities, Congenital	0.001085767	4	0	BeFree
Cervix carcinoma	0.001085767	4	0	BeFree
Autosomal recessive retinitis pigmentosa	0.001085767	4	0	BeFree
Malignant neoplasm of ovary	0.001085767	4	1	BeFree
Adenoid Cystic Carcinoma	0.000814326	3	0	BeFree
Congenital Foot Deformity	0.000814326	3	0	BeFree
Osteosarcoma	0.000814326	3	0	BeFree
Malignant neoplasm of lung	0.000814326	3	0	BeFree
Osteosarcoma of bone	0.000814326	3	0	BeFree
Carcinoma of lung	0.000814326	3	0	BeFree
Sarcoma	0.000814326	3	0	BeFree
Triple Negative Breast Neoplasms	0.000814326	3	0	BeFree
Experimental Organism Basal Cell Carcinoma	0.000814326	3	0	BeFree
Merkel cell carcinoma	0.000542884	2	0	BeFree
Carcinoma, Papillary	0.000542884	2	0	BeFree
Cleft Lip	0.000542884	2	0	BeFree
Cleft Palate	0.000542884	2	0	BeFree
Colorectal Carcinoma	0.000542884	2	0	BeFree
Keloid	0.000542884	2	0	BeFree
Actinic keratosis	0.000542884	2	0	BeFree
melanoma	0.000542884	2	0	BeFree
Psoriasis	0.000542884	2	0	BeFree
Rhabdomyosarcoma	0.000542884	2	0	BeFree
Salivary Gland Neoplasms	0.000542884	2	0	BeFree
Dermatologic disorders	0.000542884	2	0	BeFree
Aphthous Stomatitis	0.000542884	2	0	BeFree
Ulcerative stomatitis	0.000542884	2	0	BeFree
Tuberculosis	0.000542884	2	0	BeFree
B-Cell Lymphomas	0.000542884	2	0	BeFree
Familial benign pemphigus	0.000542884	2	0	BeFree
Epstein-Barr Virus Infections	0.000542884	2	0	BeFree
Small cell carcinoma of lung	0.000542884	2	0	BeFree
Atrophic condition of skin	0.000542884	2	0	BeFree
Adenocarcinoma of lung (disorder)	0.000542884	2	0	BeFree
Esophageal carcinoma	0.000542884	2	0	BeFree
Malignant neoplasm of testis	0.000542884	2	0	BeFree
Undifferentiated carcinoma	0.000542884	2	0	BeFree
Adenosquamous carcinoma	0.000542884	2	0	BeFree
Mucoepidermoid Carcinoma	0.000542884	2	0	BeFree
Neuroendocrine Tumors	0.000542884	2	0	BeFree
Papillary thyroid carcinoma	0.000542884	2	0	BeFree
Split foot	0.000542884	2	0	BeFree
Minor oral aphthous ulceration	0.000542884	2	0	BeFree
Carcinoma of larynx	0.000542884	2	0	BeFree
Secondary malignant neoplasm of lymph node	0.000542884	2	0	BeFree
Testicular malignant germ cell tumor	0.000542884	2	0	BeFree
ovarian neoplasm	0.000542884	2	0	BeFree
Ductal Carcinoma	0.000542884	2	0	BeFree
Mammary Neoplasms	0.000542884	2	1	BeFree
Colorectal Cancer	0.000542884	2	0	BeFree
Non-Neoplastic Disorder	0.000542884	2	0	BeFree
Photoreceptor degeneration	0.000542884	2	1	BeFree
Asthma	0.000271442	1	0	BeFree
Barrett Esophagus	0.000271442	1	0	BeFree
Bladder Neoplasm	0.000271442	1	0	BeFree
Malignant neoplasm of skin	0.000271442	1	0	BeFree
Malignant neoplasm of thyroid	0.000271442	1	0	BeFree
Noninfiltrating Intraductal Carcinoma	0.000271442	1	0	BeFree
Uterine Cervical Neoplasm	0.000271442	1	0	BeFree
Chondroblastoma	0.000271442	1	0	BeFree
Diabetic Retinopathy	0.000271442	1	0	BeFree
Esophageal Neoplasms	0.000271442	1	0	BeFree
Giant Cell Tumors	0.000271442	1	0	BeFree
Influenza	0.000271442	1	0	BeFree
Keratoconjunctivitis Sicca	0.000271442	1	0	BeFree
Lymphoma, Follicular	0.000271442	1	0	BeFree
Mycosis Fungoides	0.000271442	1	0	BeFree
Myoepithelioma	0.000271442	1	0	BeFree
Nephroblastoma	0.000271442	1	0	BeFree
Osteoblastoma	0.000271442	1	0	BeFree
Skin Neoplasms	0.000271442	1	0	BeFree
Soft Tissue Neoplasms	0.000271442	1	0	BeFree
Syndactyly	0.000271442	1	0	BeFree
Teratoma	0.000271442	1	0	BeFree
Lymphoma, T-Cell, Cutaneous	0.000271442	1	0	BeFree
Adenosis of Breast	0.000271442	1	0	BeFree
Bone Cysts, Aneurysmal	0.000271442	1	0	BeFree
Malignant neoplasm of mouth	0.000271442	1	0	BeFree
Secondary malignant neoplasm of lung	0.000271442	1	0	BeFree
Hidrotic Ectodermal Dysplasia	0.000271442	1	0	BeFree
Ki-1+ Anaplastic Large Cell Lymphoma	0.000271442	1	0	BeFree
Giant Cell Tumor of Bone	0.000271442	1	0	BeFree
Fibroadenoma	0.000271442	1	0	BeFree
Trophoblastic Tumor, Placental Site	0.000271442	1	0	BeFree
Verrucous carcinoma	0.000271442	1	0	BeFree
Lip and Oral Cavity Carcinoma	0.000271442	1	0	BeFree
Comedone	0.000271442	1	0	BeFree
Pseudolymphoma	0.000271442	1	0	BeFree
Pancreatic carcinoma	0.000271442	1	0	BeFree
Inflammatory Breast Carcinoma	0.000271442	1	0	BeFree
Gallbladder adenocarcinoma	0.000271442	1	0	BeFree
Laryngeal Squamous Cell Carcinoma	0.000271442	1	0	BeFree
Fundus Albipunctatus	0.000271442	1	0	BeFree
Night blindness, congenital stationary	0.000271442	1	0	BeFree
Malignant neoplasm of pancreas	0.000271442	1	0	BeFree
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site	0.000271442	1	0	BeFree
Hematologic Neoplasms	0.000271442	1	0	BeFree
Craniofacial Abnormalities	0.000271442	1	0	BeFree
Poikiloderma of Kindler	0.000271442	1	0	BeFree
Visual symptoms	0.000271442	1	0	BeFree
Malignant neoplasm of esophagus	0.000271442	1	0	BeFree
Recurrent Carcinoma	0.000271442	1	0	BeFree
Thyroid carcinoma	0.000271442	1	0	BeFree
Squamous cell carcinoma of skin	0.000271442	1	0	BeFree
Squamous cell carcinoma of mouth	0.000271442	1	0	BeFree
invasive cancer	0.000271442	1	0	BeFree
Disorder of macula of retina	0.000271442	1	0	BeFree
Drusen	0.000271442	1	0	BeFree
Large cell neuroendocrine carcinoma	0.000271442	1	0	BeFree
Metaplastic carcinoma	0.000271442	1	0	BeFree
Degenerative disorder	0.000271442	1	0	BeFree
Severe visual impairment	0.000271442	1	0	BeFree
Adenocarcinoma of large intestine	0.000271442	1	0	BeFree
B-Cell Lymphoma, Unclassifiable, with Features Intermediate between Diffuse Large B-Cell Lymphoma and Classical Hodgkin Lymphoma	0.000271442	1	0	BeFree
Epithelioma	0.000271442	1	0	BeFree
Malignant Conversion	0.000271442	1	0	BeFree
Skin Carcinogenesis	0.000271442	1	0	BeFree
Limbal stem cell deficiency	0.000271442	1	0	BeFree
Idiopathic Pulmonary Fibrosis	0.000271442	1	0	BeFree
Cleft lip, isolated	0.000271442	1	0	BeFree
Nasopharyngeal carcinoma	0.000271442	1	0	BeFree
Proliferative Inflammatory Atrophy	0.000271442	1	0	BeFree