RGS2(regulator of G-protein signaling 2) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

1q31
基因染色体位置图

基因简述

基因简述

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis. [provided by RefSeq, Aug 2009]

[中文简述(自动翻译):]  G蛋白信号（RGS）家族成员的调节是充当异的G蛋白G的阿尔法亚基GTP酶激活蛋白（GAP）调节分子。 RGS蛋白能够停用在Gi的αG蛋白亚基，转到α和Gq蛋白的α亚型。他们驾驶的G蛋白进入它们的无效GDP结合的形式。 G蛋白信号2的稳压器属于这个家庭。该蛋白质作为骨髓分化的介体和在白血病可能发挥作用。 [由RefSeq的，2009年08月提供]

OMIM数据库中对RGS2基因的介绍     Wikipedia数据库中对RGS2基因的介绍

基因序列

基因序列

RGS2基因的碱基序列：[NCBI]

基因突变

基因突变

RGS2基因的碱基突变：           显示全部snp
rs4606       rs756409       rs1418718       rs1418719       rs2746071       rs2746072       rs2746073       rs3767488       rs3835598       rs4657836       rs5779653       rs10607546       rs11540017       rs12084818       rs12130714       rs12565735       rs12566194       rs16834852       rs16834859       rs17647363       rs35052149       rs45577436       rs45577832       rs45594334       rs61688645       rs72738504       rs73062286       rs73062287       rs74466425       rs74626315       rs74716343       rs75930797       rs76212967       rs76294834       rs76586144       rs76763381       rs76959506      
rs77813283       rs79060998       rs79675470       rs80221024       rs80255659       rs111239724       rs111335636       rs111568602       rs111983702       rs112707798       rs115662257       rs115700720       rs116000720       rs116203871       rs116425030       rs117986927       rs118097442       rs138241304       rs139141127       rs139237239       rs140700575       rs140811638       rs141030117       rs141407357       rs141804594       rs141821884       rs142499684       rs142540600       rs143288784       rs143501391       rs144230394       rs144636974       rs145125159       rs145396662       rs146292708       rs146718044       rs146862218       rs147119695       rs147219133       rs147952367       rs148456943       rs148489044       rs148646791       rs148929202       rs149228054       rs149943054       rs181527380       rs181615370       rs182386643       rs182872670       rs183357408       rs183691150       rs184161050       rs184293069       rs185750160       rs186283475       rs186294942       rs187019587       rs187275495       rs187487338       rs188646735       rs188922079       rs189464491       rs189578388       rs190312590       rs191105548       rs191864309       rs191910605       rs192146711       rs192640504       rs192740723       rs193051407       rs200208332       rs200339834       rs200505450       rs200879749       rs200916949       rs201233692       rs201642180       rs202013918       rs367757316       rs367837079       rs367901296       rs368290103       rs369259338       rs369752935       rs369970749       rs370673230       rs371653540       rs371719737       rs371843799       rs372230356       rs372280634       rs372424395       rs372850701       rs373469911       rs373722429       rs374205631       rs374873881       rs375268381       rs375755008       rs376366314       rs376593019       rs376661452       rs377637167       rs377647978       rs527451039       rs527993832       rs529258249       rs529917908       rs530358353       rs530693440       rs532047415       rs533091961       rs533136845       rs533676666       rs534048579       rs534938259       rs535332395       rs535887327       rs535919491       rs536686953       rs536899610       rs537520459       rs537691552       rs540083135       rs541275903       rs541337584       rs541727738       rs542087615       rs543153513       rs544056286       rs544387496       rs545745194       rs545810386       rs547214256       rs547422176       rs548262021       rs548571417       rs549231729       rs550804984       rs551188703       rs551636926       rs552159626       rs552200895       rs552763353       rs553747342       rs554363743       rs554600855       rs555596097       rs557799878       rs558037302       rs558081612       rs558306841       rs558660303       rs558928473       rs559718177       rs559926073       rs561748762       rs561812912       rs562507384       rs562689527       rs563194658       rs563683359       rs564483322       rs564935106       rs567163247       rs568116427       rs568328150       rs569128026       rs569334463       rs570096349       rs570476212       rs570478454       rs570641074       rs571387036       rs572396397       rs573552607       rs573669936       rs575649602       rs576132273       rs577101444       rs577574239       rs577684741       rs578099868       rs578211074       rs745369264       rs745440695       rs745471760       rs746511201       rs747156983       rs747343810       rs747431689       rs747799456       rs747921480       rs747947152       rs747988941       rs748479395       rs748585377       rs749060505       rs749110520       rs749383315       rs749759020       rs749978129       rs750288329       rs750495025       rs750858569       rs751189088       rs751279008       rs751634239       rs751657005       rs751951851       rs752129550       rs752316198       rs752905071       rs753347945       rs753745198       rs754050437       rs754132319       rs754481476       rs754843878       rs755076642       rs755372508       rs755523667       rs755650674       rs756087171       rs756254339       rs756378137       rs756711570       rs757007105       rs757017108       rs757061626       rs757270622       rs757460149       rs757727614       rs757964706       rs758347713       rs758534414       rs759349861       rs759569562       rs759666784       rs759744224       rs759877100       rs759895235       rs760231323       rs760249368       rs760297309       rs760672186       rs760844773       rs761217478       rs761391867       rs761395133       rs762016295       rs762233679       rs762277643       rs762304757       rs762553991       rs762913377       rs762939759       rs763184394       rs763303561       rs763371548       rs763656876       rs763847693       rs764271951       rs764528890       rs764565973       rs764628956       rs765273898       rs765431581       rs765465115       rs765543153       rs765692586       rs766027565       rs766126102       rs766308836       rs766529182       rs766607664       rs767044489       rs767213298       rs767257495       rs767540087       rs767970789       rs768260823       rs768499221       rs768501145       rs768656623       rs768780407       rs769235048       rs769405605       rs769502722       rs769845556       rs770357541       rs771360634       rs771445381       rs772026755       rs772206894       rs772262559       rs772402393       rs772418851       rs772640231       rs772940819       rs773290344       rs773800785       rs773888827       rs774043545       rs774373203       rs774590409       rs774619759       rs774856176       rs775228976       rs775439827       rs775605317       rs775686830       rs775756603       rs776083561       rs776204539       rs776294332       rs776888943       rs777261219       rs777664764       rs778058761       rs778221511       rs778439302       rs779391212       rs779963247       rs780414391       rs780440673       rs781181895       rs781487798       rs781765572      

基因表达

基因表达

RGS2基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CCAGCAAATATGGTCTTGC
57
TTTGAAGTCTTCACAGGCC
58
GTTCAACACGACTGCAGAC
60
GAAGTAGCTCAAACGGGTC
58
AAATTCCTCTACTCCTGGGA
58
CAAGACCATATTTGCTGGC
57
GTTCAACACGACTGCAGAC
60
TAGCTCAAACGGGTCTTCC
59
CAGCAAATATGGTCTTGCTG
58
TTTGAAGTCTTCACAGGCC
58
CTGTTCAACACGACTGCAG
60
TAGCTCAAACGGGTCTTCC
59
CCAGCAAATATGGTCTTGCT
59
TTGAAGTCTTCACAGGCCA
59
AAATTCCTCTACTCCTGGGA
58
GCAAGACCATATTTGCTGG
57
AAATTCCTCTACTCCTGGGA
58
CAGCAAGACCATATTTGCTG
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

RGS2基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RGS2基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001965
P41220(UniProtKB)
IPI
GO:0005096
P41220(UniProtKB)
IMP
GO:0005515
P41220(UniProtKB)
IPI
GO:0005515
P41220(UniProtKB)
IPI
GO:0005515
P41220(UniProtKB)
IPI
GO:0005515
P41220(UniProtKB)
IPI
GO:0005516
P41220(UniProtKB)
TAS
GO:0005634
P41220(UniProtKB)
IDA
GO:0005634
P41220(UniProtKB)
IDA
GO:0005730
P41220(UniProtKB)
IEA
GO:0005737
P41220(UniProtKB)
IDA
GO:0005739
P41220(UniProtKB)
IEA
GO:0005829
P41220(UniProtKB)
ISS
GO:0005886
P41220(UniProtKB)
IDA
GO:0006417
P41220(UniProtKB)
IEA
GO:0007049
P41220(UniProtKB)
IEA
GO:0007283
P41220(UniProtKB)
IEA
GO:0008277
P41220(UniProtKB)
IMP
GO:0009898
P41220(UniProtKB)
ISS
GO:0010519
P41220(UniProtKB)
ISS
GO:0010614
P41220(UniProtKB)
ISS
GO:0031116
P41220(UniProtKB)
IEA
GO:0043005
P41220(UniProtKB)
IEA
GO:0043407
P41220(UniProtKB)
ISS
GO:0043547
P41220(UniProtKB)
IEA
GO:0043951
P41220(UniProtKB)
IEA
GO:0045744
P41220(UniProtKB)
ISS
GO:0048487
P41220(UniProtKB)
IEA
GO:0050873
P41220(UniProtKB)
IEA
GO:0055119
P41220(UniProtKB)
ISS
GO:0060087
P41220(UniProtKB)
IEA
GO:0060452
P41220(UniProtKB)
ISS
GO:0071877
P41220(UniProtKB)
ISS

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控RGS2基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Hypertensive disease 0.143365202 19 1 BeFree_CTD_human_GAD_LHGDN
Leukemia, Myelocytic, Acute 0.120271442 2 0 BeFree_CTD_human
Secondary Parkinson Disease 0.12 1 0 CTD_human
Stomach Neoplasms 0.12 1 0 CTD_human
Mammary Neoplasms 0.12 1 0 CTD_human
Panic Disorder 0.008458305 7 0 BeFree_GAD
Schizophrenia 0.008001298 2 1 BeFree_GAD_LHGDN
Anxiety Disorders 0.005081451 10 0 BeFree_GAD
Parkinson Disease 0.005005506 3 1 BeFree_GAD
Malignant neoplasm of urinary bladder 0.002909916 2 0 BeFree_GAD
Hypotension 0.00272435 1 0 LHGDN
Atherosclerosis 0.002638474 2 0 BeFree_GAD
Syncope 0.002638474 1 0 BeFree_GAD
Metabolic Syndrome X 0.002638474 1 0 BeFree_GAD
Malignant neoplasm of ovary 0.002638474 2 0 BeFree_GAD
Anxiety 0.002367032 1 0 GAD
Squamous cell carcinoma 0.002367032 1 0 GAD
Head and Neck Neoplasms 0.002367032 1 0 GAD
Hyperlipidemia 0.002367032 1 0 GAD
Marijuana Abuse 0.002367032 1 0 GAD
Multiple Sclerosis 0.002367032 1 0 GAD
Neoplasm Recurrence, Local 0.002367032 1 0 GAD
Postmortem Changes 0.002367032 1 0 GAD
Psychoses, Substance-Induced 0.002367032 1 0 GAD
Vasovagal syncope 0.002367032 1 0 GAD
Neoplasms, Second Primary 0.002367032 1 0 GAD
Feeling suicidal (finding) 0.002367032 1 0 GAD
Autonomic nervous system disorders 0.002367032 1 0 GAD
Blood pressure finding 0.002367032 1 2 GAD
Systemic arterial pressure 0.002367032 1 2 GAD
PANIC DISORDER 1 0.001357209 5 0 BeFree
Asthma 0.000542884 2 0 BeFree
Astrocytoma 0.000542884 2 0 BeFree
Neoplasm Metastasis 0.000542884 2 0 BeFree
Obesity 0.000542884 2 0 BeFree
Essential Hypertension 0.000542884 2 0 BeFree
Extrapyramidal sign 0.000542884 2 0 BeFree
Parkinsonian Disorders 0.000542884 2 0 BeFree
Generalized Anxiety Disorder 0.000542884 2 0 BeFree
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Carcinogenesis 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Carcinoma of bladder 0.000542884 2 0 BeFree
androgen independent prostate cancer 0.000542884 2 0 BeFree
Arteriosclerosis 0.000271442 1 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Cardiovascular Diseases 0.000271442 1 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
Diabetes Mellitus, Insulin-Dependent 0.000271442 1 0 BeFree
Hodgkin Disease 0.000271442 1 0 BeFree
Huntington Disease 0.000271442 1 0 BeFree
Phobia, Social 0.000271442 1 0 BeFree
Prostatic Neoplasms 0.000271442 1 0 BeFree
Seasonal Affective Disorder 0.000271442 1 0 BeFree
Anxiety and fear 0.000271442 1 0 BeFree
Social fear 0.000271442 1 0 BeFree
Overweight 0.000271442 1 0 BeFree
Blood Pressure Disorders 0.000271442 1 0 BeFree
Carotid Atherosclerosis 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Observation of Neuromuscular Block 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree

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