RGN(regucalcin) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

Xp11.3
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

[中文简述(自动翻译):]  由该基因编码的蛋白质是高度保守的，钙结合蛋白，其是在肝脏和肾脏中优先表达。它可以具有在钙稳态中起重要作用。在鼠的研究表明，这种蛋白还可以在老化中发挥作用，因为它显示了与年龄有关的下调。该基因是在染色体Xp11.3-Xp11.23基因簇的一部分。选择性剪接结果在多个抄本变形。 [由RefSeq的，2013年9月提供]

OMIM数据库中对RGN基因的介绍     Wikipedia数据库中对RGN基因的介绍

基因序列

基因序列

RGN基因的碱基序列：[NCBI]

基因突变

基因突变

RGN基因的碱基突变：           显示全部snp
rs782813242       rs782802984       rs782809181       rs782802055       rs782794572       rs782786434       rs782784886       rs782775416       rs782784253       rs782768854       rs782758107       rs782757831       rs782753370       rs782752992       rs782752642       rs782748186       rs782747625       rs782747416       rs782745168       rs782744206       rs782743472       rs782740897       rs782743244       rs782738678       rs782734775       rs782736320       rs782729425       rs782730477       rs782726501       rs782723229       rs782713186       rs782717609       rs782710994       rs782707703       rs782707578       rs782705034       rs782697861      
rs782688519       rs782688153       rs782687687       rs782683329       rs782683374       rs782682963       rs782682137       rs782674660       rs782681518       rs782674173       rs782670156       rs782670872       rs782664089       rs782661848       rs782661405       rs782650800       rs782660204       rs782640740       rs782645556       rs782649731       rs782635982       rs782632610       rs782621429       rs782618506       rs782613576       rs782611483       rs782609249       rs782607060       rs782602211       rs782602270       rs782598122       rs782591786       rs782590883       rs782585580       rs782584371       rs782583845       rs782582262       rs782571528       rs782575926       rs782568640       rs782563287       rs782566043       rs782557499       rs782559363       rs782559777       rs782553759       rs782549710       rs782553342       rs782549183       rs782546678       rs782543485       rs782536928       rs782534681       rs782532266       rs782528182       rs782530382       rs782518957       rs782521980       rs782509022       rs782503509       rs782496120       rs782494834       rs782490343       rs782489217       rs782483889       rs782483326       rs782483208       rs782483047       rs782475293       rs782480636       rs782472905       rs782471708       rs782468848       rs782469248       rs782467219       rs782466517       rs782461857       rs782459141       rs782459512       rs782458872       rs782457548       rs782455069       rs782453942       rs782454956       rs782450492       rs782450322       rs782448751       rs782447720       rs782446707       rs782438216       rs782446076       rs782428534       rs782423268       rs782422178       rs782418482       rs782418215       rs782414657       rs782409932       rs782412869       rs782400374       rs782403675       rs782397984       rs782396426       rs782394975       rs782393698       rs782388059       rs782389332       rs782385881       rs782365638       rs782377464       rs782349871       rs782338385       rs782338695       rs782337351       rs782334387       rs782316628       rs782314561       rs782314828       rs782305809       rs782312113       rs782305337       rs782303399       rs782303889       rs782302795       rs782293927       rs782287520       rs782287471       rs782280489       rs782274728       rs782278777       rs782265967       rs782255731       rs782254337       rs782249178       rs782251977       rs782246398       rs782238158       rs782245520       rs782235261       rs782237947       rs782229159       rs782226127       rs782223815       rs782214358       rs782209650       rs782211935       rs782206489       rs782209470       rs782203047       rs782204377       rs782202481       rs782200833       rs782198192       rs782194213       rs782195795       rs782193203       rs782192367       rs782192410       rs782191507       rs782185541       rs782186854       rs782190344       rs782176532       rs782163952       rs782167293       rs782162721       rs782161700       rs782161122       rs782151100       rs782141597       rs782143162       rs782137920       rs782140113       rs782136570       rs782136558       rs782135882       rs782132290       rs782128713       rs782128707       rs782127227       rs782110790       rs782116822       rs782100287       rs782099078       rs782094026       rs782090414       rs782086736       rs782081493       rs782079619       rs782078759       rs782070735       rs782063762       rs782062313       rs782061452       rs782059906       rs782058872       rs782054825       rs782050680       rs782048826       rs782046267       rs782046269       rs782045270       rs782044336       rs782042994       rs782040443       rs782041244       rs782030957       rs782034336       rs782030656       rs782027663       rs782024346       rs782022481       rs782003821       rs782017182       rs781997735       rs781986437       rs781985926       rs781983644       rs781983504       rs781978028       rs781977550       rs781976131       rs781976033       rs781974604       rs781975538       rs781971957       rs781967131       rs781965759       rs781963425       rs781961740       rs781962162       rs781961151       rs781959761       rs781955617       rs781959519       rs781949904       rs781955408       rs781944810       rs781942217       rs781941175       rs781941064       rs781940574       rs781932759       rs781939399       rs781932236       rs781931968       rs781928887       rs781926753       rs781928851       rs781926384       rs781914720       rs781911945       rs781911462       rs781906358       rs781904945       rs781905653       rs781903639       rs781898113       rs781897723       rs781894921       rs781897443       rs781890815       rs781891891       rs781893894       rs781886939       rs781886297       rs781880265       rs781886076       rs781876971       rs781875659       rs781871793       rs781869363       rs781870383       rs781867031       rs781865838       rs781866538       rs781857427       rs781856366       rs781848198       rs781833857       rs781832578       rs781832190       rs781831568       rs781825154       rs781824995       rs781824643       rs781823551       rs781820299       rs781818772       rs781816305       rs781805113       rs781801869       rs781801233       rs781799312       rs781794700       rs781790153       rs781789966       rs781784678       rs781785419       rs781784673       rs573885701       rs560214541       rs545818642       rs542199715       rs541181531       rs537908151       rs531686236       rs377723488       rs376834455       rs377264025       rs377535619       rs376108151       rs376331031       rs375868199       rs375482595       rs375254414       rs374670126       rs374714195       rs373172217       rs373577391       rs372947736       rs372645399       rs372919878       rs372187464       rs372082655       rs371270982       rs371816285       rs370232608       rs370535299       rs369024325       rs369634471       rs368609419       rs368575955       rs368581184       rs368495600       rs202231318       rs368196625       rs201674719       rs201477424       rs201514577       rs201459962       rs201215269       rs200769291       rs200384685       rs200091296       rs199632624       rs199942482       rs199530732       rs193073496       rs192792256       rs192577064       rs192493514       rs192360768       rs192317673       rs191941530       rs191806904       rs191652870       rs191223032       rs191194548       rs190930458       rs190745870       rs190691224       rs190576853       rs190104452       rs190140668       rs190045560       rs189991490       rs189888659       rs189914509       rs189815266       rs189668386       rs189641579       rs189512262       rs189300619       rs189060660       rs188959748       rs188915407       rs188530588       rs188509598       rs188277698       rs187746697       rs187373173       rs187255868       rs186968265       rs186930068       rs186595835       rs186492290       rs186422427       rs186291858       rs185956303       rs185797449       rs185398132       rs185294055       rs185247069       rs185188660       rs185066604       rs184844167       rs184798482       rs184658792       rs184508635       rs184367976       rs184239933       rs184232619       rs184194088       rs184139230       rs184026100       rs183875696       rs183793995       rs183723285       rs183263156       rs183142600       rs182781671       rs182531710       rs182374898       rs182253868       rs182064519       rs181945645       rs181775372       rs181454818       rs181316861       rs181113975       rs181112823       rs180977062       rs180954168       rs151173351       rs150192613       rs150203186       rs149885920       rs149709787       rs149446370       rs148491669       rs148366844       rs148051057       rs147490967       rs147522316       rs147045438       rs147028738       rs146720462       rs146742385       rs146177434       rs145476160       rs144994343       rs144882710       rs144220959       rs144158257       rs143534173       rs143395908       rs143304641       rs143290491       rs143192923       rs143124627       rs143093820       rs142948872       rs142686569       rs142558644       rs141625569       rs141157296       rs140980311       rs140887409       rs140834342       rs140355620       rs140381313       rs139078395       rs139038506       rs139029447       rs138891006       rs138747840       rs138519058       rs138412897       rs138188418       rs114785765       rs114545397       rs113603034       rs113309696       rs112603094       rs112133000       rs112002161       rs111705868       rs111902972       rs111697791       rs111659497       rs79830960       rs75576458       rs76211714       rs79010746       rs73484401       rs62591336       rs73201972       rs59603115       rs56185835       rs41305373       rs34431960       rs34055415       rs28421055       rs12853360       rs12556310       rs12009166       rs7882477       rs7877675       rs6611330       rs6611328       rs6611327       rs6521178       rs5952997       rs5952996       rs5952414       rs5952413       rs5906327       rs5906326       rs5906324       rs5906322       rs5906321       rs5905584       rs5905583       rs5012957       rs4824599       rs4824418       rs4551488       rs4503212       rs4480242       rs3814905       rs14312      

基因表达

基因表达

RGN基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ACAGGACAGATCTCCAACC
59
CTCAGCATCAATACACATTCCA
59
AACCTTCAGATTCCCAGGG
59
ATTATCTGTGCGGGTGAGAG
60
TTTCAAGATAACTGGTCTGGG
58
GAAGACCTGTCCTCATCCC
59
CTTCTATTACATTGACAGCCTGTC
60
TTCTGCGGTTGGAGATCTG
60
AACCTTCAGATTCCCAGGG
59
TTATCTGTGCGGGTGAGAG
59
CAGGACAGATCTCCAACCG
60
CTCAGCATCAATACACATTCCA
59
AACACGTCACTGATCTCCC
59
ATACTGGAGACTCACCACAC
59
GAAACACGTCACTGATCTCC
59
TACTGGAGACTCACCACAC
58
AAACACGTCACTGATCTCC
58
TACTGGAGACTCACCACAC
58
CAACCTTCAGATTCCCAGG
58
TTATCTGTGCGGGTGAGAG
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

RGN基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RGN基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001822
Q15493(UniProtKB)
IEA
GO:0004341
Q15493(UniProtKB)
IDA
GO:0004341
Q15493(UniProtKB)
IDA
GO:0005509
Q15493(UniProtKB)
ISS
GO:0005509
Q15493(UniProtKB)
IDA
GO:0005634
Q15493(UniProtKB)
ISS
GO:0005634
Q15493(UniProtKB)
IDA
GO:0005654
Q15493(UniProtKB)
IDA
GO:0005737
Q15493(UniProtKB)
ISS
GO:0005829
Q15493(UniProtKB)
IEA
GO:0006469
Q15493(UniProtKB)
IEA
GO:0006874
Q15493(UniProtKB)
ISS
GO:0007283
Q15493(UniProtKB)
IEA
GO:0007568
Q15493(UniProtKB)
IEA
GO:0008270
Q15493(UniProtKB)
IDA
GO:0010867
Q15493(UniProtKB)
IEA
GO:0010907
Q15493(UniProtKB)
IEA
GO:0010922
Q15493(UniProtKB)
IEA
GO:0019853
Q15493(UniProtKB)
IEA
GO:0030234
Q15493(UniProtKB)
IEA
GO:0032515
Q15493(UniProtKB)
IEA
GO:0032781
Q15493(UniProtKB)
ISS
GO:0034260
Q15493(UniProtKB)
IEA
GO:0043066
Q15493(UniProtKB)
IEA
GO:0043547
Q15493(UniProtKB)
IEA
GO:0045019
Q15493(UniProtKB)
IEA
GO:0045723
Q15493(UniProtKB)
IEA
GO:0050680
Q15493(UniProtKB)
IEA
GO:0050848
Q15493(UniProtKB)
ISS
GO:0051344
Q15493(UniProtKB)
IEA
GO:0097421
Q15493(UniProtKB)
IEA
GO:1901318
Q15493(UniProtKB)
IEA
GO:1901671
Q15493(UniProtKB)
IEA
GO:1901896
Q15493(UniProtKB)
IEA
GO:1902679
Q15493(UniProtKB)
IEA
GO:1903011
Q15493(UniProtKB)
IEA
GO:1903052
Q15493(UniProtKB)
IEA
GO:1903611
Q15493(UniProtKB)
IEA
GO:1903625
Q15493(UniProtKB)
IEA
GO:1903629
Q15493(UniProtKB)
IEA
GO:1903634
Q15493(UniProtKB)
IEA
GO:2000279
Q15493(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控RGN基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Kidney Diseases 0.12 1 0 CTD_human
Liver Cirrhosis, Experimental 0.12 1 0 CTD_human
Liver Neoplasms, Experimental 0.12 1 0 CTD_human
Liver carcinoma 0.082171535 9 0 BeFree_RGD
Diabetes Mellitus, Experimental 0.08 1 0 RGD
Hyperlipidemia 0.08 1 0 RGD
Liver Failure, Acute 0.00272435 1 0 LHGDN
Liver neoplasms 0.001357209 5 0 BeFree
Carcinogenesis 0.001085767 4 0 BeFree
Malignant neoplasm of breast 0.000542884 2 0 BeFree
Malignant neoplasm of liver 0.000542884 2 0 BeFree
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Breast Carcinoma 0.000542884 2 0 BeFree
Mental Depression 0.000271442 1 0 BeFree
Depressive disorder 0.000271442 1 0 BeFree
Kidney Neoplasm 0.000271442 1 0 BeFree
Osteomalacia 0.000271442 1 0 BeFree
Invasive Ductal Breast Carcinoma 0.000271442 1 0 BeFree
Hepatocarcinogenesis 0.000271442 1 0 BeFree
Non-Neoplastic Disorder 0.000271442 1 0 BeFree

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