RAC2(ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2))

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

22q13.1
基因染色体位置图

基因简述

基因简述

This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]

[中文简述(自动翻译):]  这个基因编码的小三磷酸鸟苷（GTP）-metabolizing蛋白质的Ras超家族的成员。所编码的蛋白质定位于质膜，在那里它调节多种工艺，例如分泌，吞噬作用，和细胞极化。该蛋白质的活性也参与活性氧的产生。在这种基因突变与嗜中性粒细胞性免疫缺陷综合征有关。没有为第6号染色体这个基因假基因[由RefSeq的，2013年7月提供]

OMIM数据库中对RAC2基因的介绍     Wikipedia数据库中对RAC2基因的介绍

基因序列

基因序列

RAC2基因的碱基序列：[NCBI]

基因突变

基因突变

RAC2基因的碱基突变：           显示全部snp
rs6572       rs739041       rs739042       rs929023       rs1064498       rs1476002       rs2032481       rs2157206       rs2213430       rs2213431       rs2213432       rs2227067       rs2227068       rs2227069       rs2230919       rs2239773       rs2239774       rs2239775       rs2284036       rs2284037       rs2284038       rs2285109       rs2285110       rs2413458       rs4140869       rs4140870       rs4820276       rs4820277       rs4821611       rs4821612       rs4821613       rs4821614       rs5005163       rs5756573       rs5845330       rs5995400       rs5995401      
rs5995403       rs5995404       rs5995405       rs5995406       rs5995407       rs6000621       rs6000622       rs6000623       rs6000624       rs6147616       rs7288684       rs7292284       rs8135343       rs8136713       rs8137698       rs9607431       rs9607432       rs9607433       rs9607434       rs9607435       rs9610680       rs9610682       rs9610683       rs9610684       rs9610685       rs9610686       rs9619663       rs9622584       rs9622587       rs9622588       rs9622589       rs9622590       rs9798725       rs11089830       rs11089831       rs11308176       rs11329932       rs11374583       rs11703487       rs11704316       rs11704488       rs12166336       rs12166968       rs12168928       rs12170612       rs12484515       rs12484612       rs13054143       rs13057244       rs13058338       rs16997975       rs28430401       rs35634144       rs35883266       rs55644139       rs55668512       rs55743339       rs55755700       rs55806854       rs55810010       rs55819536       rs55900964       rs55917599       rs55964914       rs55970640       rs55994325       rs56016773       rs56034561       rs56040131       rs56047979       rs56073008       rs56074805       rs56089907       rs56123503       rs56132943       rs56148284       rs56152096       rs56187326       rs56235347       rs56265548       rs56278411       rs56285130       rs56338712       rs56340942       rs56341212       rs56381241       rs56409124       rs56409223       rs56733795       rs57289360       rs58341088       rs62235085       rs67537084       rs67970560       rs70950543       rs71317033       rs71317034       rs71317035       rs71324848       rs71328605       rs71328608       rs72550751       rs73413218       rs73413225       rs73413233       rs73881652       rs73881653       rs73881654       rs73881655       rs73881657       rs73887443       rs73889256       rs73889258       rs74184852       rs74186886       rs74196236       rs74198159       rs74199778       rs74201862       rs74203585       rs74211028       rs74216978       rs74221164       rs74562686       rs74850957       rs75182739       rs75375644       rs76741815       rs76929303       rs77088001       rs77121303       rs77136644       rs77160582       rs77225760       rs77417006       rs78009969       rs78353659       rs78590052       rs79075893       rs79198890       rs79443032       rs79646817       rs79688282       rs79799102       rs80269564       rs111163944       rs111163945       rs111336934       rs111472808       rs111550018       rs111552866       rs111610073       rs111793008       rs112071138       rs112257772       rs112442581       rs112504554       rs112526278       rs112567201       rs113035432       rs113662685       rs113792455       rs113826170       rs113916421       rs114050303       rs114079284       rs114158133       rs114237336       rs114247881       rs114733204       rs114749947       rs114861109       rs114943146       rs114954834       rs115077809       rs115106695       rs115317725       rs115402118       rs115403731       rs115414326       rs115719337       rs115882909       rs115890462       rs115957545       rs116118746       rs116144494       rs116445218       rs116459759       rs116782454       rs116833643       rs117094326       rs117160285       rs117830350       rs117998449       rs137954936       rs138329312       rs138762569       rs138768472       rs138811708       rs138855108       rs138891460       rs139068317       rs139104575       rs139282443       rs139357361       rs139394730       rs139516372       rs139710005       rs139811404       rs140073815       rs140329126       rs140350670       rs140362459       rs140405812       rs140543568       rs140690810       rs140909410       rs141074733       rs141269495       rs141308774       rs141358630       rs141405861       rs141501087       rs141670283       rs141727556       rs142073919       rs142272949       rs142496628       rs142896017       rs143474074       rs143632581       rs143901197       rs143994118       rs144137162       rs144184927       rs144207985       rs144224728       rs144293335       rs144338192       rs144539258       rs144828173       rs145058410       rs145497564       rs145711085       rs145736749       rs145875953       rs146048269       rs146228716       rs146326950       rs146620835       rs146632090       rs146740448       rs146751562       rs147161880       rs147217849       rs147287487       rs147324381       rs147584399       rs147759121       rs147850388       rs147886654       rs148042333       rs148169045       rs148306225       rs148568509       rs148735594       rs148799451       rs148891799       rs148934477       rs149390285       rs149443346       rs149817921       rs149911901       rs150228196       rs150293149       rs150386101       rs150751528       rs150758516       rs150782757       rs150908716       rs150997289       rs151011193       rs151057038       rs151153221       rs151307781       rs151310685       rs180937295       rs181241200       rs181295204       rs181321690       rs181791842       rs181902251       rs182168307       rs182240533       rs182290525       rs182712210       rs183013960       rs183138184       rs183170358       rs183568415       rs183863405       rs184010438       rs184082285       rs184253578       rs184469395       rs184717638       rs184740207       rs185088537       rs185232531       rs185280268       rs186012130       rs186031536       rs186171644       rs186422084       rs186734565       rs186830578       rs186881846       rs188082914       rs188156247       rs188184789       rs188399986       rs188504473       rs188513513       rs188898315       rs189283605       rs189449878       rs189707904       rs189813729       rs190239453       rs190487991       rs191234773       rs191328211       rs191387292       rs191591580       rs191773310       rs192073653       rs192275140       rs192280588       rs192456330       rs192479531       rs192595342       rs192713128       rs192986866       rs199595759       rs199795253       rs199904054       rs200023542       rs200215350       rs200341320       rs200676821       rs200779512       rs200969255       rs201150296       rs201500108       rs201536161       rs201965451       rs201989515       rs367837744       rs367947647       rs368410563       rs368475314       rs368714879       rs369009395       rs369134505       rs369270392       rs369433004       rs369464677       rs369612629       rs369662829       rs369714470       rs370007318       rs370046077       rs370074322       rs370114359       rs370129583       rs370715463       rs370821323       rs371002273       rs371179748       rs371268518       rs371289893       rs371491612       rs371599545       rs371789770       rs372072944       rs372376321       rs372431493       rs372987442       rs373324269       rs373879011       rs373926430       rs373971208       rs374379711       rs374566760       rs374723131       rs374813762       rs374925865       rs375031039       rs375093215       rs375636571       rs376050623       rs376434337       rs376517131       rs376828859       rs377460514       rs377530680       rs527570883       rs527708118       rs527739755       rs527740080       rs527797965       rs527802517       rs527872573       rs528321555       rs528324222       rs528341117       rs528391347       rs528719632       rs528903593       rs528954820       rs529322558       rs530107832       rs530158732       rs530577072       rs530578926       rs530605338       rs530643504       rs530651151       rs530771340       rs530853255       rs531040974       rs531068115       rs531071399       rs531193462       rs531730022       rs531760772       rs532226666       rs532322887       rs532411617       rs532904401       rs533064153       rs533200294       rs533256516       rs533273434       rs533402765       rs533410453       rs533456217       rs533468537       rs533599400       rs533827923       rs533982666       rs534748127       rs534866900       rs534929853       rs534993641       rs535085825       rs535130428       rs535299913       rs535815109       rs535868079       rs536105121       rs536129454       rs536233225       rs536316123       rs536321900       rs536859736       rs537058156       rs537225854       rs537297532       rs537363894       rs537429964       rs537454075       rs537517406       rs537662278       rs537890841       rs538038477       rs538082563       rs538102675       rs538477957       rs538511937       rs538513028       rs538606863       rs538647312       rs538649208       rs538856757       rs539102776       rs539162775       rs539297579       rs539660525       rs539758459       rs540044169       rs540058525       rs540094083       rs540164041       rs540274489       rs540289569       rs540466935       rs540493148       rs540675412       rs541129979       rs541146124       rs541194272       rs541397475       rs541600809       rs541601244       rs541619457       rs541685341       rs541850760       rs542449877       rs542513970       rs542622641       rs542730360       rs542811282       rs542821680       rs543965278       rs543969145       rs544002252       rs544002275       rs544008174       rs544050423       rs544549792       rs544613703       rs544684686       rs544775704       rs544860541       rs545205813       rs545249028       rs545442580       rs545659406       rs545673924       rs545745434       rs546045065       rs546354146       rs546604784       rs546611876       rs546699814       rs546855740       rs546901775       rs546980365       rs546994910       rs546995002       rs547156742       rs547184949       rs547205195       rs547288592       rs547786394       rs547800974       rs547878894       rs548100144       rs548445913       rs549126617       rs549201412       rs549230356       rs549310499       rs549323905       rs549356937       rs549367562       rs549369331       rs549639393       rs550337980       rs550356688       rs550419833       rs550635218       rs550643077       rs550751475       rs551224622       rs551352072       rs551439373       rs551558731       rs551778458       rs551867782       rs552084286       rs552149372       rs552170023       rs552456032       rs552672947       rs552827791       rs553037154       rs553236379       rs553353767       rs553505104       rs553644596       rs553949037       rs554019235       rs554440945       rs554532806       rs554535499       rs554559004       rs554620662       rs554622316       rs554626111       rs554672786       rs555006025       rs555481919       rs555689791       rs555726122       rs555754829       rs555876188       rs555895499       rs555954462       rs556951056       rs557080795       rs557103620       rs557221152       rs557629394       rs557753055       rs557870230       rs558018606       rs558133351       rs558155839       rs558211867       rs558417971       rs558435600       rs558668305       rs558748094       rs559060554       rs559251938       rs559276504       rs559358411       rs559497396       rs559502035       rs559659859       rs559779691       rs559805317       rs559868277       rs559932230       rs559989080       rs560062564       rs560171419       rs560260787       rs560507806       rs560799783       rs561006154       rs561100294       rs561108904       rs561547070       rs561689653       rs561955432       rs562105988       rs562144352       rs562188292       rs562207703       rs562293440       rs562480668       rs562505387       rs562655219       rs563217917       rs563276808       rs563310744       rs563442152       rs563452968       rs563493184       rs563695973       rs563743342       rs563901026       rs563922478       rs564209989       rs564296040       rs564580319       rs564643716       rs564708882       rs564843622       rs564879886       rs564972701       rs565031463       rs565064594       rs565094966       rs565765856       rs565777880       rs565916394       rs566164793       rs566375376       rs566499411       rs566582331       rs566621126       rs566714042       rs566851767       rs567174006       rs567440805       rs567573793       rs567598732       rs567679079       rs567846956       rs568197760       rs568348731       rs568544407       rs568606986       rs568738922       rs568760331       rs568880833       rs568956219       rs569002402       rs569099659       rs569240599       rs569588310       rs569708390       rs569771597       rs569829444       rs569953916       rs569972703       rs569992133       rs570402383       rs571412230       rs571441218       rs571462402       rs571653894       rs571806892       rs571810045       rs571819430       rs572328390       rs572376387       rs572685276       rs572748591       rs572809102       rs572911444       rs572999021       rs573802446       rs573977167       rs573992200       rs574041876       rs574195945       rs574201319       rs574325969       rs574345453       rs575039159       rs575074037       rs575209632       rs575326806       rs575338369       rs575346181       rs575351371       rs575433571       rs575461593       rs575493259       rs575519167       rs575548102       rs575699146       rs575789640       rs575863356       rs575983218       rs576291977       rs576533479       rs576535702       rs576557697       rs576653167       rs576736123       rs576872372       rs577068096       rs577455866       rs577468322       rs577469268       rs577605155       rs577739507       rs577807198       rs577923492       rs577959348       rs577981173       rs578052035       rs578129660       rs745481315       rs746023079       rs746043077       rs746584502       rs746834278       rs746891580       rs747196476       rs747251446       rs747807459       rs747917580       rs748613308       rs748808662       rs748915671       rs749549392       rs749761322       rs749816337       rs750030956       rs750103219       rs750313450       rs750682796       rs750689195       rs750951037       rs751463906       rs751478410       rs751478661       rs751523605       rs752041123       rs752473596       rs752891184       rs752897291       rs753114755       rs753270998       rs754038603       rs754081675       rs754120892       rs754452931       rs754862203       rs755080873       rs755097815       rs755454147       rs755574428       rs755869758       rs756235135       rs756498304       rs756797181       rs757037858       rs757164212       rs757686862       rs757928548       rs758014943       rs758128596       rs758461304       rs758489377       rs758867543       rs759109933       rs759162928       rs759471295       rs759555563       rs759868418       rs760197517       rs760272207       rs760366847       rs761393334       rs761403484       rs761458473       rs761751786       rs762411252       rs762851576       rs763673351       rs763789341       rs764189477       rs764752738       rs764821645       rs764957886       rs765318577       rs765498124       rs765502233       rs765767432       rs766066554       rs766537276       rs766569039       rs766621971       rs766735118       rs766780288       rs767222826       rs767340560       rs767514506       rs767737173       rs767941433       rs768190971       rs768357934       rs768459775       rs768513144       rs768931430       rs769695039       rs769735815       rs769841365       rs770222890       rs770554080       rs770734512       rs770795800       rs771160247       rs771297786       rs771321602       rs771516943       rs771590910       rs771823232       rs771922318       rs772302068       rs772523685       rs772949111       rs773555428       rs773631805       rs773684818       rs773894520       rs774073343       rs774474267       rs774727606       rs775272396       rs775274909       rs775533737       rs775778136       rs775938952       rs775968192       rs776389642       rs776743351       rs776796919       rs776912739       rs776972828       rs777156619       rs777290534       rs778182086       rs778432994       rs778871264       rs778969295       rs780585104       rs780638404       rs781027367       rs781040687       rs781088657       rs781564729      

基因表达

基因表达

RAC2基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank

转录因子

转录因子

      尚未收录相关数据

基因本体信息

RAC2基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RAC2基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005525
B1AH77(UniProtKB)
IEA
GO:0005622
B1AH77(UniProtKB)
IEA
GO:0007264
B1AH77(UniProtKB)
IEA
GO:0005525
B1AH78(UniProtKB)
IEA
GO:0005622
B1AH78(UniProtKB)
IEA
GO:0007264
B1AH78(UniProtKB)
IEA
GO:0005525
B1AH79(UniProtKB)
IEA
GO:0005622
B1AH79(UniProtKB)
IEA
GO:0007264
B1AH79(UniProtKB)
IEA
GO:0005525
B1AH80(UniProtKB)
IEA
GO:0005622
B1AH80(UniProtKB)
IEA
GO:0007264
B1AH80(UniProtKB)
IEA
GO:0003924
P15153(UniProtKB)
IEA
GO:0005525
P15153(UniProtKB)
IMP
GO:0005635
P15153(UniProtKB)
IEA
GO:0005829
P15153(UniProtKB)
IDA
GO:0005829
P15153(UniProtKB)
TAS
GO:0005829
P15153(UniProtKB)
TAS
GO:0005829
P15153(UniProtKB)
TAS
GO:0005829
P15153(UniProtKB)
TAS
GO:0005829
P15153(UniProtKB)
TAS
GO:0005829
P15153(UniProtKB)
TAS
GO:0005829
P15153(UniProtKB)
TAS
GO:0005886
P15153(UniProtKB)
TAS
GO:0005886
P15153(UniProtKB)
TAS
GO:0005886
P15153(UniProtKB)
TAS
GO:0005886
P15153(UniProtKB)
TAS
GO:0005925
P15153(UniProtKB)
IDA
GO:0006935
P15153(UniProtKB)
IEA
GO:0007015
P15153(UniProtKB)
IMP
GO:0007165
P15153(UniProtKB)
TAS
GO:0007186
P15153(UniProtKB)
IEA
GO:0007264
P15153(UniProtKB)
IEA
GO:0008284
P15153(UniProtKB)
IEA
GO:0010310
P15153(UniProtKB)
TAS
GO:0010592
P15153(UniProtKB)
IMP
GO:0010810
P15153(UniProtKB)
IMP
GO:0019887
P15153(UniProtKB)
IEA
GO:0030027
P15153(UniProtKB)
IDA
GO:0030031
P15153(UniProtKB)
IEA
GO:0030168
P15153(UniProtKB)
TAS
GO:0030670
P15153(UniProtKB)
TAS
GO:0030670
P15153(UniProtKB)
TAS
GO:0042129
P15153(UniProtKB)
IEA
GO:0043304
P15153(UniProtKB)
IEA
GO:0045453
P15153(UniProtKB)
IEA
GO:0045859
P15153(UniProtKB)
IEA
GO:0051056
P15153(UniProtKB)
TAS
GO:0060263
P15153(UniProtKB)
IDA
GO:0060753
P15153(UniProtKB)
IEA
GO:0070062
P15153(UniProtKB)
IDA
GO:0070062
P15153(UniProtKB)
IDA
GO:0071593
P15153(UniProtKB)
IMP
GO:0090023
P15153(UniProtKB)
IMP
GO:1902622
P15153(UniProtKB)
IMP
GO:1903955
P15153(UniProtKB)
IMP
GO:0005884
P15153(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控RAC2基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Neutrophil Immunodeficiency Syndrome 0.482638474 1 1 BeFree_CLINVAR_CTD_human_GAD_ORPHANET_UNIPROT
Lymphoma 0.120271442 2 0 BeFree_CTD_human
Heart Diseases 0.12 1 0 CTD_human
melanoma 0.12 1 0 CTD_human
Juvenile Myelomonocytic Leukemia 0.12 1 0 CTD_human
leukemia 0.003267234 3 0 BeFree_LHGDN
Glioma 0.00272435 1 0 LHGDN
Brain Neoplasms 0.002638474 2 0 BeFree_GAD
Lymphoma, Non-Hodgkin 0.002638474 2 0 BeFree_GAD
HIV Infections 0.002367032 1 0 GAD
Meningeal Neoplasms 0.002367032 1 1 GAD
Meningioma 0.002367032 1 1 GAD
Occupational Diseases 0.002367032 1 0 GAD
Parkinson Disease 0.002367032 1 0 GAD
Neoplasm Metastasis 0.001085767 4 0 BeFree
Immunologic Deficiency Syndromes 0.000542884 2 0 BeFree
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Liver carcinoma 0.000542884 2 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
CNS disorder 0.000271442 1 0 BeFree
Crohn Disease 0.000271442 1 0 BeFree
DiGeorge Syndrome 0.000271442 1 0 BeFree
Graves Disease 0.000271442 1 0 BeFree
Hematological Disease 0.000271442 1 0 BeFree
Inflammatory Bowel Diseases 0.000271442 1 0 BeFree
Irritable Bowel Syndrome 0.000271442 1 0 BeFree
Leukemia, Myelocytic, Acute 0.000271442 1 0 BeFree
Myeloid Leukemia, Chronic 0.000271442 1 0 BeFree
Leukemia, T-Cell 0.000271442 1 0 BeFree
Lymphopenia 0.000271442 1 0 BeFree
Osteoporosis, Postmenopausal 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Tangier Disease 0.000271442 1 0 BeFree
Qualitative abnormality of granulocyte 0.000271442 1 0 BeFree
Congenital neutropenia 0.000271442 1 0 BeFree
Familial aplasia of the vermis 0.000271442 1 0 BeFree
WHIM syndrome 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree
Precursor B-cell lymphoblastic leukemia 0.000271442 1 0 BeFree
Infantile malignant osteopetrosis 0.000271442 1 0 BeFree
Central nervous system leukaemia 0.000271442 1 0 BeFree
Recurrent infections (sinusitis and bacterial pneumonia and meningitis) 0.000271442 1 0 BeFree
Severe congenital neutropenia 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

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