PSEN1(presenilin 1) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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14q24.3
基因染色体位置图

Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene, the full-length nature of only some have been determined. [provided by RefSeq, Aug 2008]

[中文简述(自动翻译):]  阿尔茨海默氏病(AD)患者在早老蛋白的疾病进位的突变的遗传形式(PSEN1; PSEN2)或淀粉样前体蛋白(APP)。这些疾病相关的突变导致生产淀粉样蛋白-β(公元大脑中淀粉样蛋白沉积的主要成分)的较长形式的增加。早老被假定通过其对γ-分泌酶的作用来调节APP处理,酶劈开APP。此外,可以认为,在早老参与Notch受体的裂解,使得它们可以直接调节γ-分泌酶活性或本身是蛋白酶。编码不同同种型的几个可变剪接转录物变体已被发现此基因,只有部分全长性质已经确定。 [由RefSeq的,2008年8月提供]

PSEN1基因的碱基序列:[NCBI]
PSEN1基因的碱基突变:           显示全部snp
rs7523       rs165931       rs165932       rs165933       rs165934       rs165935       rs177412       rs177413       rs177414       rs177415       rs177416       rs177417       rs177418       rs214260       rs214261       rs214262       rs214263       rs214264       rs214267       rs214268       rs214269       rs214270       rs214271       rs214272       rs214273       rs214274       rs214275       rs214276       rs214277       rs214278       rs214279       rs214280       rs362339       rs362340       rs362341       rs362342       rs362343      
rs362347       rs362348       rs362349       rs362350       rs362351       rs362352       rs362353       rs362354       rs362355       rs362356       rs362357       rs362358       rs362359       rs362360       rs362361       rs362362       rs362363       rs362364       rs362365       rs362366       rs362367       rs362368       rs362369       rs362370       rs362371       rs362372       rs362374       rs362375       rs362376       rs362377       rs362378       rs362379       rs362380       rs362381       rs362382       rs362383       rs362384       rs362385       rs362387       rs362388       rs362389       rs362390       rs362391       rs362392       rs362393       rs362394       rs362395       rs362396       rs362397       rs362457       rs362458       rs362459       rs362460       rs1000008       rs1042864       rs1057852       rs1203311       rs1800839       rs1800840       rs1800844       rs2272585       rs2280791       rs2283427       rs2333030       rs3025773       rs3025774       rs3025776       rs3025777       rs3025778       rs3025779       rs3025780       rs3025781       rs3025782       rs3025783       rs3025784       rs3025785       rs3025786       rs3025787       rs3025788       rs3025789       rs3182301       rs4899458       rs7143491       rs7145968       rs7147079       rs7147896       rs7148656       rs7152131       rs7153378       rs7154061       rs7154312       rs7156668       rs7158911       rs7159873       rs7160427       rs7161030       rs7161398       rs7359038       rs8006221       rs8006497       rs8008686       rs8011335       rs8011748       rs8018725       rs8018739       rs8020594       rs8021006       rs8023183       rs9743635       rs10130116       rs10131037       rs10131356       rs10131938       rs10132644       rs10134564       rs10134874       rs10135273       rs10136281       rs10136911       rs10140990       rs10141217       rs10142471       rs10142485       rs10143618       rs10143704       rs10145927       rs10146467       rs10146743       rs10147873       rs10148612       rs10151436       rs10564849       rs11379162       rs12184969       rs12323830       rs12432944       rs12432960       rs12433115       rs12435869       rs12586604       rs12587333       rs12587379       rs12587473       rs12588591       rs12878362       rs12882830       rs12883075       rs12890801       rs12894420       rs12896793       rs13379148       rs17124867       rs17124882       rs17125150       rs17125152       rs17125457       rs17125555       rs17125721       rs17125952       rs17182181       rs17408630       rs17781788       rs17781801       rs17781809       rs17781841       rs28431180       rs28451346       rs28482166       rs28506983       rs28532025       rs28607501       rs28613010       rs28660183       rs28713521       rs28719583       rs33930642       rs34048372       rs34086577       rs34138587       rs34194809       rs34315326       rs34369135       rs34514951       rs34528538       rs34623110       rs34940341       rs35093253       rs35294154       rs35581508       rs35615325       rs35710852       rs35891140       rs35983175       rs36008515       rs45511501       rs55657666       rs55730237       rs55812918       rs55850750       rs55853751       rs56008848       rs56383209       rs57050244       rs57307382       rs57815955       rs57895054       rs58317194       rs58458484       rs59194960       rs59341951       rs59962242       rs60208626       rs60308291       rs60320273       rs60369636       rs60619903       rs60926424       rs61141098       rs61986861       rs61986862       rs61986863       rs61986865       rs61986866       rs61986877       rs61986878       rs61986879       rs61986880       rs61986881       rs61986882       rs61986883       rs61986884       rs61986885       rs61986886       rs61986887       rs61986888       rs61986889       rs61986892       rs61986893       rs61986896       rs61986897       rs61986898       rs61986899       rs61986900       rs61986901       rs61986902       rs61986903       rs61986904       rs61986928       rs63749824       rs63750082       rs63750248       rs63750323       rs63750592       rs63750831       rs63750900       rs63751174       rs63751441       rs66748161       rs67647403       rs68084031       rs71112708       rs71427179       rs71427180       rs71427181       rs71450213       rs72734454       rs72734455       rs72734456       rs72734460       rs73305007       rs73305016       rs73305034       rs73305038       rs73305043       rs73305051       rs73305053       rs73305061       rs73305064       rs74061003       rs74061004       rs74061005       rs74061006       rs74061007       rs74062647       rs74062651       rs74062653       rs74424999       rs74653211       rs74676595       rs74714816       rs74727279       rs74820432       rs74828099       rs74856884       rs74981834       rs75051290       rs75057334       rs75179141       rs75181239       rs75233854       rs75234948       rs75266743       rs75363802       rs75389647       rs75467834       rs75527985       rs75563122       rs75659473       rs75783609       rs75894497       rs75903964       rs75975162       rs76018359       rs76193270       rs76339996       rs76356675       rs76389699       rs76426658       rs76614784       rs76804037       rs76809297       rs76892416       rs76966559       rs77029422       rs77119530       rs77162241       rs77244626       rs77267908       rs77427123       rs77462509       rs77566396       rs77586895       rs77594272       rs77609029       rs77685348       rs77778105       rs77983620       rs78132128       rs78213646       rs78265930       rs78267161       rs78284376       rs78304949       rs78317792       rs78362186       rs78403601       rs78537135       rs78558172       rs78603551       rs78782780       rs78840950       rs78841957       rs78871133       rs78922928       rs78957227       rs78959774       rs79125817       rs79252718       rs79282794       rs79330921       rs79335076       rs79480249       rs79505171       rs79524837       rs79620182       rs79668701       rs79729083       rs79789313       rs79916673       rs79976215       rs80024836       rs80030711       rs80043006       rs80078500       rs80094658       rs80255040       rs80331025       rs111240255       rs111319748       rs111323647       rs111444007       rs111471856       rs111475952       rs111557056       rs111607475       rs111650497       rs111657154       rs111694806       rs111704578       rs111759355       rs111840015       rs111945130       rs112024830       rs112101802       rs112249292       rs112287075       rs112451138       rs112456911       rs112549106       rs112560505       rs112724703       rs112890654       rs112911413       rs113071478       rs113074873       rs113149216       rs113270982       rs113332832       rs113386556       rs113426609       rs113449244       rs113485120       rs113494605       rs113774566       rs113832178       rs113901631       rs113937326       rs113991031       rs113994990       rs114000457       rs114004599       rs114014192       rs114017123       rs114229922       rs114285804       rs114317083       rs114336572       rs114378630       rs114386278       rs114445862       rs114467135       rs114498425       rs114499894       rs114576149       rs114615055       rs114616749       rs114634160       rs114653436       rs114679458       rs114776088       rs114782352       rs114944042       rs114952061       rs115076395       rs115123722       rs115164402       rs115322640       rs115334263       rs115376785       rs115546755       rs115555746       rs115620087       rs115697938       rs115702167       rs115717679       rs115739628       rs115760359       rs115865530       rs115882151       rs115891135       rs115909396       rs116061552       rs116107724       rs116226928       rs116296065       rs116300507       rs116314689       rs116321567       rs116395726       rs116426584       rs116442941       rs116443630       rs116466962       rs116521228       rs116616518       rs116640707       rs116825425       rs116882898       rs117170264       rs117236337       rs117394753       rs117414600       rs117484602       rs117490301       rs117563918       rs117636016       rs117643810       rs117826622       rs117869781       rs117973146       rs118079222       rs118140704       rs118144727       rs121917809       rs137863233       rs137920817       rs137921477       rs137925118       rs137925179       rs137926268       rs138061744       rs138119474       rs138178179       rs138181695       rs138205623       rs138245461       rs138247564       rs138311229       rs138312917       rs138396026       rs138425111       rs138479907       rs138527450       rs138601588       rs138620990       rs138638872       rs138678883       rs138683430       rs138686510       rs138803782       rs138852262       rs138855796       rs138871096       rs138902912       rs138907808       rs138923281       rs138972350       rs138973092       rs139048521       rs139058678       rs139071886       rs139085364       rs139112977       rs139222371       rs139255158       rs139391117       rs139392169       rs139503683       rs139521885       rs139537733       rs139574327       rs139669544       rs139863395       rs139870552       rs139953121       rs139961867       rs139964536       rs140012487       rs140027376       rs140064975       rs140082086       rs140089088       rs140164309       rs140169796       rs140189461       rs140238059       rs140346058       rs140366572       rs140372057       rs140447679       rs140461257       rs140481942       rs140525811       rs140584670       rs140628433       rs140669416       rs140710323       rs140717635       rs140746584       rs140763414       rs140797307       rs140863358       rs140865740       rs140943336       rs140971082       rs141000002       rs141114226       rs141117435       rs141138081       rs141145106       rs141165471       rs141187583       rs141253181       rs141287499       rs141365251       rs141411304       rs141457172       rs141535751       rs141552089       rs141655641       rs141656976       rs141675857       rs141689717       rs141730494       rs141799841       rs141804925       rs141822345       rs141833880       rs141974188       rs142010550       rs142030001       rs142053866       rs142093869       rs142112766       rs142189156       rs142195160       rs142207090       rs142346467       rs142355580       rs142405996       rs142413545       rs142429755       rs142457921       rs142482786       rs142494111       rs142499364       rs142533546       rs142625534       rs142638003       rs142799518       rs142823714       rs142849869       rs142868766       rs142880209       rs142910718       rs142982254       rs143121060       rs143124022       rs143206356       rs143229105       rs143258167       rs143344129       rs143439617       rs143503368       rs143587069       rs143606369       rs143622535       rs143648541       rs143683769       rs143702018       rs143763464       rs143782428       rs143783639       rs143795534       rs143844465       rs143856904       rs143861413       rs143891048       rs143926761       rs143988789       rs143989467       rs144066042       rs144084598       rs144123666       rs144133432       rs144157631       rs144291400       rs144330235       rs144330434       rs144417985       rs144455736       rs144466165       rs144467541       rs144522334       rs144572101       rs144669072       rs144680586       rs144725513       rs144737303       rs144777325       rs144829044       rs144940990       rs144980869       rs145022303       rs145060922       rs145082857       rs145101663       rs145154229       rs145175423       rs145214439       rs145370761       rs145406041       rs145412152       rs145427499       rs145441531       rs145472990       rs145496879       rs145510210       rs145551368       rs145575064       rs145583388       rs145607385       rs145694990       rs145727060       rs145840421       rs145930265       rs145930949       rs145949063       rs145949376       rs146071629       rs146072458       rs146172047       rs146190421       rs146224505       rs146269771       rs146306647       rs146323073       rs146351908       rs146477595       rs146516501       rs146592791       rs146635005       rs146729897       rs146753793       rs146833389       rs146833908       rs146853341       rs146855665       rs146875208       rs146942755       rs147032287       rs147049211       rs147183622       rs147183738       rs147199304       rs147219036       rs147290166       rs147434149       rs147434342       rs147502410       rs147502524       rs147519551       rs147622397       rs147638016       rs147690813       rs147691281       rs147796167       rs147813948       rs147866042       rs147882990       rs147903216       rs147905463       rs148004093       rs148009306       rs148024075       rs148040036       rs148092059       rs148143836       rs148213656       rs148219738       rs148305194       rs148356871       rs148405986       rs148441567       rs148475766       rs148530636       rs148546614       rs148612389       rs148686567       rs148807303       rs148841069       rs148912177       rs148914974       rs148927215       rs148929071       rs148998082       rs149088789       rs149119646       rs149135830       rs149166990       rs149209990       rs149210266       rs149299753       rs149312199       rs149385120       rs149457419       rs149562759       rs149577006       rs149595412       rs149616406       rs149643873       rs149698571       rs149701354       rs149750118       rs149765364       rs149873062       rs149893475       rs149924956       rs149978366       rs150050804       rs150079540       rs150191750       rs150220443       rs150235879       rs150292692       rs150301281       rs150307958       rs150357761       rs150429321       rs150435397       rs150538359       rs150550252       rs150562889       rs150575029       rs150695289       rs150743438       rs150745286       rs150763023       rs150764501       rs150800565       rs150816995       rs150831684       rs150837586       rs150940566       rs151082255       rs151098329       rs151111068       rs151150329       rs151170492       rs151205233       rs151274214       rs151325212       rs180823246       rs180849770       rs180875304       rs180878265       rs180886992       rs180898071       rs181054325       rs181057130       rs181081592       rs181081779       rs181101742       rs181266679       rs181270951       rs181284178       rs181295963       rs181390169       rs181420275       rs181509052       rs181519087       rs181543549       rs181556440       rs181722099       rs181726819       rs181785243       rs181785527       rs181788101       rs181795653       rs181808070       rs181825217       rs181919055       rs181967382       rs181981078       rs181985347       rs181991465       rs182212850       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rs543471703       rs543504374       rs543540913       rs543640004       rs543670801       rs543759822       rs543787152       rs543797875       rs543841936       rs543854037       rs543882851       rs543920424       rs543948769       rs543993486       rs544030867       rs544031190       rs544038608       rs544174377       rs544210287       rs544213758       rs544251391       rs544254690       rs544352893       rs544379511       rs544420200       rs544487832       rs544494673       rs544494971       rs544612439       rs544807309       rs544893380       rs545059941       rs545097747       rs545098875       rs545131315       rs545131607       rs545232576       rs545244095       rs545260276       rs545270090       rs545271126       rs545308120       rs545439814       rs545515859       rs545619962       rs545627699       rs545666290       rs545673812       rs545716734       rs545731488       rs545833750       rs545838429       rs545840983       rs545847431       rs545884446       rs545951029       rs545971793       rs545991340       rs546148878       rs546160228       rs546175191       rs546195102       rs546211854       rs546336401       rs546349237       rs546360831       rs546391770       rs546422149       rs546471309       rs546609932       rs546698281       rs546797618       rs546849116       rs546876974       rs546900251       rs547011941       rs547014327       rs547031331       rs547042060       rs547147441       rs547185521       rs547378176       rs547412673       rs547443814       rs547549246       rs547579643       rs547617537       rs547623041       rs547708731       rs547743578       rs547767835       rs547838673       rs547891259       rs547900252       rs548061503       rs548077451       rs548113870       rs548150697       rs548176898       rs548193365       rs548215897       rs548244295       rs548251656       rs548288002       rs548322586       rs548394117       rs548417229       rs548453832       rs548481843       rs548489616       rs548544310       rs548594211       rs548607017       rs548627655       rs548712900       rs548767297       rs548786883       rs548841684       rs548852446       rs548858449       rs548878380       rs548879419       rs549022777       rs549039988       rs549059248       rs549099953       rs549100609       rs549137642       rs549176770       rs549252467       rs549320940       rs549421462       rs549432238       rs549467030       rs549535330       rs549536983       rs549562229       rs549575619       rs549604209       rs549608770       rs549609306       rs549699559       rs549701546       rs549742690       rs549815187       rs549817184       rs549884966       rs549933935       rs549939146       rs549955841       rs549972328       rs549975849       rs550002014       rs550022048       rs550067518       rs550086496       rs550089025       rs550138815       rs550141411       rs550162338       rs550173655       rs550223893       rs550238427       rs550275535       rs550343284       rs550355231       rs550426619       rs550534396       rs550609806       rs550665245       rs550679159       rs550739639       rs550871423       rs550932939       rs550939871       rs550954569       rs551070046       rs551094056       rs551170718       rs551207332       rs551209945       rs551210001       rs551228949       rs551246692       rs551270493       rs551393986       rs551395826       rs551462990       rs551474326       rs551512952       rs551583095       rs551597008       rs551618275       rs551633086       rs551648073       rs551657220       rs551696111       rs551780641       rs551817377       rs551902966       rs551903081       rs551905698       rs551939737       rs551953411       rs552092749       rs552133556       rs552237363       rs552354541       rs552448113       rs552451936       rs552481597       rs552485032       rs552515125       rs552595280       rs552627930       rs552662940       rs552691012       rs552718246       rs552810428       rs552851649       rs552864532       rs552941035       rs552954017       rs552984671       rs553013941       rs553079999       rs553188425       rs553189487       rs553228618       rs553261933       rs553263464       rs553331021       rs553408002       rs553511016       rs553546038       rs553580587       rs553582848       rs553596502       rs553688923       rs553691585       rs553723390       rs553723699       rs553736950       rs553773636       rs553804789       rs553820765       rs553898801       rs553968596       rs553973095       rs554020121       rs554039014       rs554041116       rs554092907       rs554126878       rs554175516       rs554248045       rs554259970       rs554265638       rs554298277       rs554299058       rs554310525       rs554458653       rs554461749       rs554590654       rs554605830       rs554628070       rs554647962       rs554677652       rs554744599       rs554783173       rs554858864       rs554919330       rs554921039       rs554974712       rs554996321       rs555030615       rs555049436       rs555056057       rs555150760       rs555183416       rs555187174       rs555201705       rs555292516       rs555314845       rs555344557       rs555351933       rs555548728       rs555608494       rs555616411       rs555617277       rs555648829       rs555656308       rs555685027       rs555731901       rs555895778       rs555895920       rs555932531       rs555938026       rs555987907       rs556049537       rs556059607       rs556061647       rs556100454       rs556147068       rs556193070       rs556254447       rs556259919       rs556287832       rs556289551       rs556299654       rs556326451       rs556401968       rs556460917       rs556537775       rs556560166       rs556688457       rs556789528       rs556813523       rs557003107       rs557077759       rs557139255       rs557189118       rs557220442       rs557247957       rs557288733       rs557343419       rs557402516       rs557409892       rs557521528       rs557528526       rs557572509       rs557581715       rs557586590       rs557649513       rs557701527       rs557715058       rs557739432       rs557753040       rs557755410       rs557786557       rs557806863       rs557831165       rs557878381       rs557927352       rs557959863       rs557998511       rs558018349       rs558107191       rs558115765       rs558115853       rs558169263       rs558296580       rs558328183       rs558360296       rs558401935       rs558418546       rs558434473       rs558466146       rs558471553       rs558507613       rs558544799       rs558584625       rs558647571       rs558733563       rs558825875       rs558898126       rs558906462       rs558969058       rs559015884       rs559021045       rs559067827       rs559193105       rs559221214       rs559232223       rs559257889       rs559343267       rs559364832       rs559453059       rs559455884       rs559485868       rs559498366       rs559535261       rs559538102       rs559715028       rs559715033       rs559722991       rs559836384       rs559895662       rs559988409       rs560052122       rs560079238       rs560091980       rs560207075       rs560207155       rs560208504       rs560242968       rs560259805       rs560265370       rs560296547       rs560337173       rs560342467       rs560387944       rs560420877       rs560433382       rs560448251       rs560449246       rs560455045       rs560556392       rs560558938       rs560595334       rs560630555       rs560693858       rs560741389       rs560780088       rs560820843       rs560857524       rs560885666       rs560887568       rs560998577       rs561032572       rs561060686       rs561093474       rs561102761       rs561172541       rs561240559       rs561339071       rs561413591       rs561417189       rs561453067       rs561480637       rs561587777       rs561638393       rs561642378       rs561674765       rs561715468       rs561770478       rs561787836       rs561824740       rs561840061       rs561892265       rs561905167       rs561932540       rs561946279       rs561962337       rs562067703       rs562099274       rs562136139       rs562147547       rs562150930       rs562173745       rs562258439       rs562277793       rs562290636       rs562315927       rs562353206       rs562374809       rs562376197       rs562411635       rs562450338       rs562481752       rs562584657       rs562608051       rs562619386       rs562625477       rs562644299       rs562664224       rs562686985       rs562710736       rs562733261       rs562889925       rs562924906       rs563018986       rs563021515       rs563199097       rs563211565       rs563263950       rs563327348       rs563330043       rs563422732       rs563459557       rs563472748       rs563525383       rs563558461       rs563573153       rs563710386       rs563734399       rs563749233       rs563773430       rs563912898       rs563953471       rs563956596       rs563989315       rs563992088       rs564069007       rs564097663       rs564218908       rs564268652       rs564281625       rs564310984       rs564321511       rs564404577       rs564440047       rs564490926       rs564591921       rs564592962       rs564626869       rs564729161       rs564743486       rs564840699       rs564842245       rs564845554       rs564885012       rs564987355       rs565006875       rs565033937       rs565086696       rs565216273       rs565259238       rs565288158       rs565338924       rs565393164       rs565579294       rs565674846       rs565745883       rs565751266       rs565795309       rs565824536       rs565888917       rs565926375       rs565942079       rs565972477       rs565976568       rs565996594       rs566008136       rs566015579       rs566047498       rs566077284       rs566113957       rs566115873       rs566176713       rs566194421       rs566301886       rs566408509       rs566447360       rs566481953       rs566510310       rs566520853       rs566542756       rs566558589       rs566596264       rs566600750       rs566742120       rs566760377       rs566795256       rs566808180       rs566833862       rs566842842       rs566845589       rs566914706       rs566968209       rs566979881       rs566984378       rs567021449       rs567072770       rs567090489       rs567118609       rs567118665       rs567134128       rs567154919       rs567210692       rs567228074       rs567524016       rs567560768       rs567626419       rs567645483       rs567663120       rs567725268       rs567742195       rs567780627       rs567817615       rs567820463       rs567855571       rs567868905       rs567918923       rs567933217       rs567940282       rs568093198       rs568129871       rs568131652       rs568168329       rs568181348       rs568194142       rs568214900       rs568227981       rs568230975       rs568248682       rs568251929       rs568318853       rs568329384       rs568363633       rs568420160       rs568432296       rs568460425       rs568469551       rs568497767       rs568532621       rs568547787       rs568681560       rs568722981       rs568741200       rs568814612       rs568887817       rs568930445       rs568952237       rs568966020       rs569005122       rs569141866       rs569218791       rs569235299       rs569258375       rs569280213       rs569321656       rs569393568       rs569418473       rs569431165       rs569450712       rs569467597       rs569482154       rs569493344       rs569533437       rs569571306       rs569597522       rs569649989       rs569682048       rs569722047       rs569769165       rs569857101       rs569858965       rs569886286       rs570130617       rs570172362       rs570238489       rs570255516       rs570278810       rs570290867       rs570400503       rs570404012       rs570454514       rs570474027       rs570563162       rs570584451       rs570604592       rs570623283       rs570642073       rs570774605       rs570808816       rs570834943       rs570864982       rs570991268       rs571028225       rs571068935       rs571099005       rs571218451       rs571236187       rs571279658       rs571344413       rs571434401       rs571524399       rs571600800       rs571652765       rs571825723       rs571873003       rs571900892       rs572002708       rs572022100       rs572085113       rs572119311       rs572145921       rs572149208       rs572182689       rs572275227       rs572284686       rs572329394       rs572337768       rs572343288       rs572343601       rs572439776       rs572448841       rs572470222       rs572712899       rs572734554       rs572770137       rs572786054       rs572798051       rs572822828       rs572830535       rs572888932       rs572924331       rs573181284       rs573250391       rs573325637       rs573325852       rs573357205       rs573362065       rs573456804       rs573542085       rs573614525       rs573769917       rs573778278       rs573808461       rs573888348       rs573926508       rs573948801       rs573987880       rs574067615       rs574069889       rs574106702       rs574123715       rs574138476       rs574270215       rs574374227       rs574429300       rs574451985       rs574457327       rs574525529       rs574528005       rs574596967       rs574602588       rs574666941       rs574671310       rs574703741       rs574837074       rs574926076       rs574941431       rs574950495       rs574976324       rs575046416       rs575111367       rs575122322       rs575138549       rs575148584       rs575244414       rs575408589       rs575428437       rs575482072       rs575568437       rs575605579       rs575633921       rs575652870       rs575717623       rs575745672       rs575754374       rs575779932       rs575795137       rs575813631       rs575845029       rs575908720       rs575930008       rs575947856       rs575952097       rs576014151       rs576074610       rs576127513       rs576143828       rs576192890       rs576210394       rs576310779       rs576322359       rs576360731       rs576398303       rs576398340       rs576433476       rs576434645       rs576468207       rs576496602       rs576515346       rs576634775       rs576671368       rs576694761       rs576731507       rs576762765       rs576790776       rs576843157       rs576880310       rs576882779       rs576982865       rs577050496       rs577059307       rs577113601       rs577121712       rs577128548       rs577161171       rs577264909       rs577269096       rs577398268       rs577412933       rs577441009       rs577446560       rs577518529       rs577543709       rs577618419       rs577656915       rs577771481       rs577804115       rs577833879       rs577837150       rs577874674       rs577947701       rs577975097       rs577980368       rs578068582       rs578076171       rs578106130       rs578187684       rs578218136       rs578226242       rs578237909       rs745315765       rs745393397       rs745694325       rs745845857       rs746032670       rs746087815       rs746270612       rs746347339       rs746638387       rs746691776       rs746839057       rs746937343       rs747224464       rs747281728       rs747363386       rs747495809       rs747622052       rs747750345       rs747835539       rs748115292       rs748488045       rs748595733       rs748605328       rs748608184       rs748891711       rs749093893       rs749249788       rs749502194       rs749784719       rs750352441       rs750585566       rs750705611       rs750708163       rs750726999       rs750870919       rs750981436       rs751258598       rs751800891       rs751974771       rs752304817       rs752665713       rs752737031       rs752833058       rs753413086       rs753457678       rs753510892       rs753684066       rs754037857       rs754084958       rs754391762       rs754392688       rs754537407       rs755161885       rs755402092       rs755634855       rs755937539       rs756256461       rs756309757       rs756539660       rs756576165       rs756764981       rs756816679       rs756871556       rs756920958       rs757147759       rs757428219       rs757610546       rs757698754       rs757999622       rs758038439       rs758201010       rs758419639       rs758564824       rs758759034       rs758814165       rs759120634       rs759384156       rs759499223       rs759538127       rs760051592       rs760139599       rs760141976       rs760158803       rs760244944       rs760283723       rs760615714       rs760648712       rs760760368       rs761010563       rs761079214       rs761376196       rs761496722       rs761876896       rs762141719       rs762700122       rs763006524       rs763024617       rs763091433       rs763180479       rs763453503       rs763638380       rs763831389       rs763991845       rs764054413       rs764128019       rs764451732       rs764563967       rs764930114       rs764971634       rs765021336       rs765167125       rs765462902       rs765670175       rs765890474       rs765891278       rs766060557       rs766185838       rs766248021       rs766482390       rs766630576       rs766798700       rs766834989       rs766998814       rs767032985       rs767054124       rs767146336       rs767625974       rs767718789       rs767871228       rs768069021       rs768409524       rs768433317       rs768521549       rs768730001       rs768923334       rs769125155       rs769265539       rs769318960       rs769650189       rs770079295       rs770291603       rs770310070       rs770380350       rs770414902       rs770625924       rs770771372       rs770874103       rs771002035       rs771041272       rs771225789       rs771477972       rs771515240       rs771695417       rs772022929       rs772162506       rs772573771       rs772667522       rs772731175       rs772984560       rs773074564       rs773126194       rs773231702       rs773436137       rs773871073       rs774033846       rs774257366       rs774691383       rs774769033       rs774915811       rs775379696       rs775543665       rs775877656       rs775926772       rs776054093       rs776076782       rs776191347       rs776278107       rs776429004       rs776529193       rs776584385       rs776683638       rs776902006       rs777093611       rs777371921       rs777427451       rs777545298       rs777640525       rs777734426       rs777923890       rs778244504       rs778630379       rs778740074       rs778783858       rs778800054       rs778861365       rs779160409       rs779296437       rs779909280       rs780119074       rs780232050       rs780407685       rs780414593       rs780429161       rs780461228       rs780676862       rs780780565       rs780796290       rs781376659       rs781431904       rs781538426       rs796663872       rs869082774       rs869285500      

PSEN1基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CTGTACGTAGCCAGAATGAC
58
TAGATAATGGCTCAGGGTGG
59
GTATAATGCAGAAAGAGCCTGTC
60
CTTTGGCATGAACAGCCTG
60
CCACCTGAGCAATACTAATGAC
59
AGATAATGGCTCAGGGTGG
59
TTCGTATGCTGGTTGAAACAG
59
ACCACACCATTGTTGAGGA
59
CGTAGCCAGAATGACAATAGAG
59
TCCATTAGATAATGGCTCAGGG
60
CGTAGCCAGAATGACAATAGAG
59
TCCATTAGATAATGGCTCAGGG
60
AATATGGCAGAAGGAGACCC
59
CTCCCTTTCTGTGCTTTCTG
59
CCACCTGAGCAATACTAATGAC
59
TAGATAATGGCTCAGGGTGG
59
ATGGGCAGCTAATCTATACCC
59
CAGCATTCAGAATTGAGTGCA
60
CCACCTGAGCAATACTAATGAC
59
TAGATAATGGCTCAGGGTGG
59
      尚未收录相关数据

PSEN1基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

PSEN1基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0000139
E7ES96(UniProtKB)
IEA
GO:0004190
E7ES96(UniProtKB)
IEA
GO:0005789
E7ES96(UniProtKB)
IEA
GO:0007219
E7ES96(UniProtKB)
IEA
GO:0016021
E7ES96(UniProtKB)
IEA
GO:0016485
E7ES96(UniProtKB)
IEA
GO:0035556
E7ES96(UniProtKB)
IEA
GO:0004190
G3V2B1(UniProtKB)
IEA
GO:0005634
G3V2B1(UniProtKB)
IDA
GO:0005794
G3V2B1(UniProtKB)
IDA
GO:0016021
G3V2B1(UniProtKB)
IEA
GO:0016485
G3V2B1(UniProtKB)
IEA
GO:0030054
G3V2B1(UniProtKB)
IDA
GO:0035556
G3V2B1(UniProtKB)
IEA
GO:0004190
G3V2G7(UniProtKB)
IEA
GO:0005634
G3V2G7(UniProtKB)
IDA
GO:0005794
G3V2G7(UniProtKB)
IDA
GO:0016021
G3V2G7(UniProtKB)
IEA
GO:0016485
G3V2G7(UniProtKB)
IEA
GO:0030054
G3V2G7(UniProtKB)
IDA
GO:0035556
G3V2G7(UniProtKB)
IEA
GO:0004190
G3V3P0(UniProtKB)
IEA
GO:0005634
G3V3P0(UniProtKB)
IDA
GO:0005794
G3V3P0(UniProtKB)
IDA
GO:0016021
G3V3P0(UniProtKB)
IEA
GO:0016485
G3V3P0(UniProtKB)
IEA
GO:0030054
G3V3P0(UniProtKB)
IDA
GO:0035556
G3V3P0(UniProtKB)
IEA
GO:0004190
G3V3Z0(UniProtKB)
IEA
GO:0005634
G3V3Z0(UniProtKB)
IDA
GO:0005794
G3V3Z0(UniProtKB)
IDA
GO:0016021
G3V3Z0(UniProtKB)
IEA
GO:0016485
G3V3Z0(UniProtKB)
IEA
GO:0030054
G3V3Z0(UniProtKB)
IDA
GO:0035556
G3V3Z0(UniProtKB)
IEA
GO:0004190
G3V449(UniProtKB)
IEA
GO:0005634
G3V449(UniProtKB)
IDA
GO:0005794
G3V449(UniProtKB)
IDA
GO:0016021
G3V449(UniProtKB)
IEA
GO:0016485
G3V449(UniProtKB)
IEA
GO:0030054
G3V449(UniProtKB)
IDA
GO:0035556
G3V449(UniProtKB)
IEA
GO:0004190
G3V499(UniProtKB)
IEA
GO:0005634
G3V499(UniProtKB)
IDA
GO:0005794
G3V499(UniProtKB)
IDA
GO:0016021
G3V499(UniProtKB)
IEA
GO:0016485
G3V499(UniProtKB)
IEA
GO:0030054
G3V499(UniProtKB)
IDA
GO:0035556
G3V499(UniProtKB)
IEA
GO:0004190
G3V4M0(UniProtKB)
IEA
GO:0005634
G3V4M0(UniProtKB)
IDA
GO:0005794
G3V4M0(UniProtKB)
IDA
GO:0016021
G3V4M0(UniProtKB)
IEA
GO:0016485
G3V4M0(UniProtKB)
IEA
GO:0030054
G3V4M0(UniProtKB)
IDA
GO:0035556
G3V4M0(UniProtKB)
IEA
GO:0004190
G3V4P4(UniProtKB)
IEA
GO:0005634
G3V4P4(UniProtKB)
IDA
GO:0005794
G3V4P4(UniProtKB)
IDA
GO:0016021
G3V4P4(UniProtKB)
IEA
GO:0016485
G3V4P4(UniProtKB)
IEA
GO:0030054
G3V4P4(UniProtKB)
IDA
GO:0035556
G3V4P4(UniProtKB)
IEA
GO:0004190
G3V519(UniProtKB)
IEA
GO:0005634
G3V519(UniProtKB)
IDA
GO:0005794
G3V519(UniProtKB)
IDA
GO:0016021
G3V519(UniProtKB)
IEA
GO:0016485
G3V519(UniProtKB)
IEA
GO:0030054
G3V519(UniProtKB)
IDA
GO:0035556
G3V519(UniProtKB)
IEA
GO:0005634
G3V5B1(UniProtKB)
IDA
GO:0005794
G3V5B1(UniProtKB)
IDA
GO:0016020
G3V5B1(UniProtKB)
IEA
GO:0030054
G3V5B1(UniProtKB)
IDA
GO:0035556
G3V5B1(UniProtKB)
IEA
GO:0004190
H0YM52(UniProtKB)
IEA
GO:0005634
H0YM52(UniProtKB)
IDA
GO:0005794
H0YM52(UniProtKB)
IDA
GO:0016021
H0YM52(UniProtKB)
IEA
GO:0016485
H0YM52(UniProtKB)
IEA
GO:0030054
H0YM52(UniProtKB)
IDA
GO:0035556
H0YM52(UniProtKB)
IEA
GO:0000045
P49768(UniProtKB)
IEA
GO:0000122
P49768(UniProtKB)
IEA
GO:0000139
P49768(UniProtKB)
IEA
GO:0000186
P49768(UniProtKB)
IEA
GO:0000776
P49768(UniProtKB)
IDA
GO:0001568
P49768(UniProtKB)
IEA
GO:0001708
P49768(UniProtKB)
IEA
GO:0001756
P49768(UniProtKB)
IEA
GO:0001764
P49768(UniProtKB)
IEA
GO:0001921
P49768(UniProtKB)
IEA
GO:0001947
P49768(UniProtKB)
IEA
GO:0002244
P49768(UniProtKB)
IEA
GO:0002286
P49768(UniProtKB)
IEA
GO:0003407
P49768(UniProtKB)
IEA
GO:0004175
P49768(UniProtKB)
IDA
GO:0004190
P49768(UniProtKB)
IEA
GO:0005262
P49768(UniProtKB)
IMP
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005515
P49768(UniProtKB)
IPI
GO:0005634
P49768(UniProtKB)
IDA
GO:0005640
P49768(UniProtKB)
IDA
GO:0005739
P49768(UniProtKB)
IDA
GO:0005743
P49768(UniProtKB)
IEA
GO:0005765
P49768(UniProtKB)
IEA
GO:0005783
P49768(UniProtKB)
IDA
GO:0005783
P49768(UniProtKB)
IDA
GO:0005789
P49768(UniProtKB)
IEA
GO:0005790
P49768(UniProtKB)
IDA
GO:0005791
P49768(UniProtKB)
IDA
GO:0005794
P49768(UniProtKB)
IDA
GO:0005794
P49768(UniProtKB)
IDA
GO:0005794
P49768(UniProtKB)
IDA
GO:0005794
P49768(UniProtKB)
IDA
GO:0005813
P49768(UniProtKB)
IDA
GO:0005886
P49768(UniProtKB)
IDA
GO:0005887
P49768(UniProtKB)
IDA
GO:0006486
P49768(UniProtKB)
IEA
GO:0006509
P49768(UniProtKB)
IDA
GO:0006839
P49768(UniProtKB)
IEA
GO:0006974
P49768(UniProtKB)
IEA
GO:0006979
P49768(UniProtKB)
IEA
GO:0007175
P49768(UniProtKB)
IEA
GO:0007219
P49768(UniProtKB)
IEA
GO:0007220
P49768(UniProtKB)
TAS
GO:0007613
P49768(UniProtKB)
IEA
GO:0008013
P49768(UniProtKB)
IPI
GO:0008013
P49768(UniProtKB)
IPI
GO:0009791
P49768(UniProtKB)
IEA
GO:0009986
P49768(UniProtKB)
IEA
GO:0015031
P49768(UniProtKB)
IEA
GO:0015813
P49768(UniProtKB)
IEA
GO:0015871
P49768(UniProtKB)
IEA
GO:0016020
P49768(UniProtKB)
IDA
GO:0016021
P49768(UniProtKB)
TAS
GO:0016080
P49768(UniProtKB)
IEA
GO:0016235
P49768(UniProtKB)
IDA
GO:0016337
P49768(UniProtKB)
IMP
GO:0016485
P49768(UniProtKB)
IDA
GO:0021795
P49768(UniProtKB)
IEA
GO:0021870
P49768(UniProtKB)
IEA
GO:0021904
P49768(UniProtKB)
IEA
GO:0030054
P49768(UniProtKB)
IDA
GO:0030165
P49768(UniProtKB)
IPI
GO:0030326
P49768(UniProtKB)
IEA
GO:0030424
P49768(UniProtKB)
IEA
GO:0030426
P49768(UniProtKB)
IEA
GO:0031410
P49768(UniProtKB)
IEA
GO:0031594
P49768(UniProtKB)
IEA
GO:0031965
P49768(UniProtKB)
IDA
GO:0032436
P49768(UniProtKB)
IEA
GO:0032469
P49768(UniProtKB)
IGI
GO:0032469
P49768(UniProtKB)
IDA
GO:0034205
P49768(UniProtKB)
IEA
GO:0035253
P49768(UniProtKB)
IEA
GO:0035556
P49768(UniProtKB)
IEA
GO:0042325
P49768(UniProtKB)
IDA
GO:0042987
P49768(UniProtKB)
TAS
GO:0043011
P49768(UniProtKB)
IEA
GO:0043025
P49768(UniProtKB)
IEA
GO:0043065
P49768(UniProtKB)
IEA
GO:0043066
P49768(UniProtKB)
IDA
GO:0043085
P49768(UniProtKB)
IDA
GO:0043198
P49768(UniProtKB)
IEA
GO:0043393
P49768(UniProtKB)
IEA
GO:0043406
P49768(UniProtKB)
IEA
GO:0043524
P49768(UniProtKB)
IEA
GO:0043589
P49768(UniProtKB)
IEA
GO:0045121
P49768(UniProtKB)
IDA
GO:0045296
P49768(UniProtKB)
IBA
GO:0045893
P49768(UniProtKB)
IMP
GO:0048167
P49768(UniProtKB)
IEA
GO:0048538
P49768(UniProtKB)
IEA
GO:0048666
P49768(UniProtKB)
IEA
GO:0048705
P49768(UniProtKB)
IEA
GO:0048854
P49768(UniProtKB)
IEA
GO:0050673
P49768(UniProtKB)
IEA
GO:0050771
P49768(UniProtKB)
IEA
GO:0050820
P49768(UniProtKB)
IEA
GO:0050852
P49768(UniProtKB)
IEA
GO:0051402
P49768(UniProtKB)
IEA
GO:0051444
P49768(UniProtKB)
IEA
GO:0051563
P49768(UniProtKB)
IBA
GO:0051966
P49768(UniProtKB)
IEA
GO:0060070
P49768(UniProtKB)
IBA
GO:0060075
P49768(UniProtKB)
IEA
GO:0060999
P49768(UniProtKB)
IMP
GO:0070588
P49768(UniProtKB)
IEA
GO:0070765
P49768(UniProtKB)
IDA
GO:0098793
P49768(UniProtKB)
IEA
GO:2000059
P49768(UniProtKB)
IEA
GO:2001234
P49768(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控PSEN1基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Alzheimer's Disease 0.388772838 197 12 BeFree_CTD_human_GAD_LHGDN_MGD
Frontotemporal dementia 0.369077134 17 6 BeFree_CLINVAR_CTD_human_GAD_UNIPROT
Cardiomyopathy, Dilated, 1u 0.36 1 1 CLINVAR_CTD_human_UNIPROT
Alzheimer disease, familial, type 3 0.320271442 30 31 BeFree_CLINVAR_MGD_UNIPROT
Pick Disease of the Brain 0.247610304 19 7 BeFree_CLINVAR_CTD_human_LHGDN
Cardiomyopathy, Dilated 0.240814326 3 1 BeFree_CLINVAR_CTD_human
Alzheimer Disease, Familial, 3, with Spastic Paraparesis and Apraxia 0.24 0 2 CLINVAR_CTD_human
Neurodegenerative Disorders 0.124810009 11 1 BeFree_CTD_human_GAD
Amyloidosis 0.121085767 5 1 BeFree_CTD_human
Heart failure 0.120271442 1 1 BeFree_CLINVAR
Asphyxia Neonatorum 0.12 1 0 CTD_human
IGA Glomerulonephritis 0.12 1 0 CTD_human
Learning Disorders 0.12 1 0 CTD_human
Memory Disorders 0.12 1 0 CTD_human
Nerve Degeneration 0.12 1 0 CTD_human
Semantic Dementia 0.12 0 0 ORPHANET
Primary Progressive Nonfluent Aphasia 0.12 0 0 ORPHANET
Hidradenitis suppurativa, familial 0.12 1 0 CTD_human
Alzheimer Disease, Familial, 3, with Spastic Paraparesis and Unusual Plaques 0.12 0 0 CLINVAR
ALZHEIMER DISEASE 4 0.12 0 1 CLINVAR
ACNE INVERSA, FAMILIAL, 3 0.12 0 0 CLINVAR
Dementia 0.046016599 51 8 BeFree_GAD_LHGDN
Paraparesis, Spastic 0.020960613 18 5 BeFree_LHGDN
Familial Alzheimer Disease (FAD) 0.015200745 56 7 BeFree
Presenile dementia 0.012486326 46 10 BeFree
Alzheimer Disease, Early Onset 0.00868614 32 10 BeFree
Senile Plaques 0.007600372 28 4 BeFree
Down Syndrome 0.006905599 9 0 BeFree_GAD
Plaque, Amyloid 0.005971721 22 2 BeFree
Dysarthria 0.005720142 3 0 BeFree_LHGDN
Seizures 0.005438769 11 3 BeFree_LHGDN
Oppositional Defiant Disorder 0.004734064 2 0 GAD
Attention Deficit Disorder 0.004734064 2 0 GAD
Conduct Disorder 0.004734064 2 0 GAD
Neuroblastoma 0.004071628 15 3 BeFree
Central neuroblastoma 0.004071628 15 3 BeFree
Cerebral Amyloid Angiopathy 0.003995683 6 0 BeFree_GAD
Lewy Body Disease 0.003995683 7 0 BeFree_GAD
Myoclonus 0.003810118 4 2 BeFree_LHGDN
Parkinsonian Disorders 0.003810118 4 4 BeFree_LHGDN
Dementia, Vascular 0.003452799 4 0 BeFree_GAD
Ataxia 0.002995792 2 0 BeFree_LHGDN
Memory impairment 0.002985861 11 2 BeFree
Amyotrophic Lateral Sclerosis 0.002909916 2 4 BeFree_GAD
Mental Depression 0.002909916 3 0 BeFree_GAD
Anoxia 0.00272435 1 0 LHGDN
Deglutition Disorders 0.00272435 1 0 LHGDN
Muscle Spasticity 0.00272435 1 0 LHGDN
Impaired cognition 0.002714419 10 2 BeFree
Schizophrenia 0.002638474 2 0 BeFree_GAD
Neurofibrillary degeneration (morphologic abnormality) 0.002442977 9 8 BeFree
Narcolepsy 0.002367032 1 0 GAD
Tobacco Use Disorder 0.002367032 1 0 GAD
Age related macular degeneration 0.002367032 1 0 GAD
Alzheimer Disease, Late Onset 0.001900093 7 0 BeFree
Glioma 0.001357209 5 0 BeFree
Amyloid angiopathy 0.001357209 5 0 BeFree
Amnesia 0.001085767 4 0 BeFree
Malignant neoplasm of breast 0.001085767 4 0 BeFree
Breast Carcinoma 0.001085767 4 0 BeFree
Familial Dementia 0.001085767 4 2 BeFree
Frontotemporal Lobar Degeneration 0.001085767 4 0 BeFree
Memory Loss 0.001085767 4 0 BeFree
Depressive disorder 0.000814326 3 0 BeFree
Epilepsy 0.000814326 3 1 BeFree
Neurologic Symptoms 0.000814326 3 1 BeFree
Astrocytoma 0.000542884 2 0 BeFree
Cerebellar Ataxia 0.000542884 2 0 BeFree
Diabetes Mellitus, Non-Insulin-Dependent 0.000542884 2 0 BeFree
Adult Neuronal Ceroid Lipofuscinosis 0.000542884 2 1 BeFree
Muscle Rigidity 0.000542884 2 0 BeFree
Ovarian Carcinoma 0.000542884 2 0 BeFree
Pheochromocytoma 0.000542884 2 0 BeFree
Pituitary Diseases 0.000542884 2 0 BeFree
Spastic Paraplegia 0.000542884 2 0 BeFree
Seasonal Affective Disorder 0.000542884 2 0 BeFree
Extrapyramidal sign 0.000542884 2 0 BeFree
Cerebral atrophy 0.000542884 2 0 BeFree
Personality change 0.000542884 2 1 BeFree
Tauopathies 0.000542884 2 0 BeFree
Malignant neoplasm of ovary 0.000542884 2 0 BeFree
Mild cognitive disorder 0.000542884 2 1 BeFree
Antley-Bixler Syndrome, Autosomal Dominant 0.000542884 2 0 BeFree
GRN-related frontotemporal dementia 0.000542884 2 0 BeFree
Congenital Abnormality 0.000271442 1 0 BeFree
Adenocarcinoma 0.000271442 1 0 BeFree
Anxiety Disorders 0.000271442 1 0 BeFree
Aphasia 0.000271442 1 0 BeFree
Apraxias 0.000271442 1 0 BeFree
Malignant neoplasm of urinary bladder 0.000271442 1 0 BeFree
Brain Neoplasms 0.000271442 1 0 BeFree
Renal Cell Carcinoma 0.000271442 1 0 BeFree
Squamous cell carcinoma 0.000271442 1 0 BeFree
Cerebral Infarction 0.000271442 1 0 BeFree
Confusion 0.000271442 1 0 BeFree
Senile dementia 0.000271442 1 0 BeFree
Headache 0.000271442 1 0 BeFree
Congestive heart failure 0.000271442 1 0 BeFree
Hydrocephalus 0.000271442 1 0 BeFree
Ischemia 0.000271442 1 0 BeFree
Kidney Failure, Chronic 0.000271442 1 0 BeFree
Language Disorders 0.000271442 1 1 BeFree
Metabolic Diseases 0.000271442 1 0 BeFree
Mycoses 0.000271442 1 0 BeFree
Obesity 0.000271442 1 1 BeFree
Parkinson Disease 0.000271442 1 0 BeFree
Cerebrovascular accident 0.000271442 1 0 BeFree
Vascular Diseases 0.000271442 1 0 BeFree
Motor Neuron Disease 0.000271442 1 0 BeFree
Depressive Symptoms 0.000271442 1 0 BeFree
Psychiatric symptom 0.000271442 1 1 BeFree
Disorientation 0.000271442 1 0 BeFree
Retinal damage 0.000271442 1 0 BeFree
anxiety generalized 0.000271442 1 0 BeFree
Leukoencephalopathies 0.000271442 1 0 BeFree
Kluver-Bucy Syndrome 0.000271442 1 0 BeFree
Cortical cataract 0.000271442 1 0 BeFree
Impaired glucose tolerance 0.000271442 1 1 BeFree
Primary Progressive Aphasia (disorder) 0.000271442 1 1 BeFree
Tumor necrosis 0.000271442 1 0 BeFree
Aphasia, Progressive 0.000271442 1 0 BeFree
Sporadic Cerebral Amyloid Angiopathy 0.000271442 1 0 BeFree
Maturity onset diabetes mellitus in young 0.000271442 1 0 BeFree
Avitaminosis 0.000271442 1 0 BeFree
Neurobehavioral Manifestations 0.000271442 1 0 BeFree
Frontal lobe syndrome 0.000271442 1 0 BeFree
Progressive Neoplastic Disease 0.000271442 1 0 BeFree
Carcinoma of bladder 0.000271442 1 0 BeFree
Inclusion Body Myopathy, Sporadic 0.000271442 1 0 BeFree
Cognitive deterioration 0.000271442 1 0 BeFree
Cardiomyopathies 0.000271442 1 0 BeFree
Ovarian adenocarcinoma 0.000271442 1 0 BeFree
Precursor B-cell lymphoblastic leukemia 0.000271442 1 0 BeFree
Liver regeneration disorder 0.000271442 1 0 BeFree
Vitamin Deficiency 0.000271442 1 0 BeFree
FRAGILE X TREMOR/ATAXIA SYNDROME 0.000271442 1 0 BeFree
AURAL ATRESIA, CONGENITAL 0.000271442 1 0 BeFree
Familial encephalopathy with neuroserpin inclusion bodies 0.000271442 1 0 BeFree
Dementia, familial British 0.000271442 1 0 BeFree
Liver carcinoma 0.000271442 1 0 BeFree
clinical depression 0.000271442 1 2 BeFree
Progressive cGVHD 0.000271442 1 0 BeFree
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