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Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  预mRNA剪接发生在两个连续的转酯的步骤,以及由该基因编码的蛋白质被认为是参与前mRNA剪接和信号转导。这种蛋白属于一个激酶家族,包括丝氨酸/富含精氨酸特异性蛋白激酶和细胞周期蛋白依赖性激酶(CDK的)。该蛋白被认为是具有同源性的丝裂原活化蛋白激酶(的MAPKs)一CDK样激酶(CLK)。 [由RefSeq的,2008年7月提供]
PRPF4B基因(以及对应的蛋白质)的细胞分布位置:
PRPF4B基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Ovarian Carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Malignant neoplasm of ovary | 0.000542884 | 2 | 0 | BeFree |
| Hypercalciuria | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of stomach | 0.000271442 | 1 | 0 | BeFree |
| Tumor Progression | 0.000271442 | 1 | 0 | BeFree |
| Stomach Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Sarcoma | 0.000271442 | 1 | 0 | BeFree |
| Mammary Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Hepatocarcinogenesis | 0.000271442 | 1 | 0 | BeFree |
| Cancer Cell Growth | 0.000271442 | 1 | 0 | BeFree |
| Liver carcinoma | 0.000271442 | 1 | 0 | BeFree |
| PSEUDOHYPOALDOSTERONISM, TYPE IID | 0.000271442 | 1 | 0 | BeFree |
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