PRDM9(PR domain containing 9) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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5p14.2
基因染色体位置图

The PR domain is a protein-protein interaction module of about 100 amino acids. PR domain-containing proteins, such as PRDM9, are often involved in transcriptional regulation (Jiang and Huang, 2000 [PubMed 10668202]).[supplied by OMIM, Mar 2008]

[中文简述(自动翻译):]  公关域的约100个??氨基酸的蛋白质 - 蛋白质相互作用的模块。 PR结构域的蛋白,如PRDM9,经常参与转录调控(江和黄,2000 [考研10668202])。[由OMIM,2008年3月供应]

PRDM9基因的碱基序列:[NCBI]
PRDM9基因的碱基突变:           显示全部snp
rs1874165       rs1994929       rs2099081       rs2115262       rs2914281       rs2914282       rs2934795       rs2934796       rs2973614       rs2973615       rs2973617       rs2973631       rs3805547       rs4701224       rs6875787       rs7714612       rs7715803       rs7718359       rs7736955       rs10042274       rs10057021       rs10062249       rs10076167       rs10077095       rs11343121       rs12110132       rs13154436       rs13154437       rs13171586       rs16874437       rs16874441       rs16874445       rs16874447       rs17314231       rs34033521       rs34096414       rs35481433      
rs55825617       rs55862350       rs56001636       rs56256550       rs58945509       rs61051796       rs62342713       rs62342714       rs62342741       rs62342742       rs62342743       rs62342744       rs72739519       rs73070028       rs73742304       rs74710141       rs75883850       rs75913096       rs76559685       rs76576173       rs76625593       rs76769084       rs77223319       rs77287813       rs78218524       rs78704174       rs78754594       rs79093667       rs79684233       rs80012863       rs80083568       rs111311675       rs111393391       rs111414003       rs111538905       rs111623087       rs111823228       rs111826655       rs111910657       rs112001060       rs112157044       rs112192848       rs112334299       rs112500340       rs112501567       rs112547122       rs112666693       rs112679149       rs112815500       rs112892776       rs112916380       rs112981617       rs112989654       rs113155229       rs113446735       rs113636161       rs113723046       rs113880250       rs113958470       rs114104040       rs114307325       rs114356258       rs114460909       rs114819756       rs115020568       rs115349842       rs115687452       rs115944571       rs116421507       rs116773071       rs137923560       rs138160131       rs138840316       rs138899992       rs138966056       rs139468715       rs139548964       rs139588083       rs139754603       rs140477330       rs140874038       rs140935721       rs141299667       rs141714341       rs141880427       rs142020661       rs142021335       rs142720740       rs143292253       rs143621375       rs143951561       rs144393194       rs144673883       rs144882458       rs144981567       rs145285509       rs145670659       rs145678019       rs145702972       rs146082807       rs146505774       rs147012610       rs147347993       rs147528957       rs147608831       rs147810365       rs148101183       rs148593518       rs148796740       rs148899493       rs149026323       rs149160995       rs149362931       rs149553125       rs149604158       rs149654357       rs149888284       rs150325264       rs150409892       rs150684198       rs150947887       rs151210842       rs180815941       rs180832695       rs181064967       rs181164491       rs181204309       rs181453727       rs181528116       rs181585790       rs181670943       rs181771203       rs181819732       rs181820703       rs181949631       rs182233111       rs182569634       rs182594177       rs182712740       rs182789605       rs182841000       rs182972078       rs183034145       rs183151992       rs183288688       rs183371418       rs183384782       rs183401473       rs183638311       rs183734267       rs183743529       rs184074861       rs184327231       rs184461737       rs184527872       rs184600328       rs184661909       rs184751581       rs184753683       rs184946672       rs185150494       rs185155427       rs185214154       rs185292258       rs185548599       rs185636293       rs185750299       rs185769056       rs186121405       rs186252797       rs186504490       rs186508290       rs186537727       rs186660349       rs186937636       rs186976334       rs187091090       rs187101636       rs187127553       rs187279463       rs187402591       rs187475623       rs187524539       rs187601173       rs187685053       rs187700975       rs187869195       rs187889591       rs188025186       rs188031148       rs188185099       rs188225452       rs188381798       rs188517683       rs188847714       rs188958761       rs189069345       rs189088831       rs189435004       rs189525139       rs189703887       rs189803816       rs189908479       rs189910548       rs190030421       rs190087306       rs190138206       rs190224969       rs190572283       rs190574365       rs190582202       rs190701350       rs191066194       rs191143245       rs191157574       rs191172593       rs191376711       rs191627771       rs191909534       rs191947112       rs192069364       rs192272646       rs192310471       rs192656705       rs192777050       rs193179249       rs193211869       rs199500582       rs199546146       rs199576336       rs199586987       rs199686868       rs199698917       rs199795687       rs199802267       rs199947885       rs200008043       rs200011811       rs200064068       rs200068677       rs200176762       rs200222315       rs200350485       rs200367474       rs200381384       rs200386479       rs200479090       rs200487743       rs200539936       rs200586153       rs200620999       rs200629735       rs200636348       rs200656137       rs200658919       rs200711484       rs200723191       rs200743042       rs200775234       rs200830061       rs200870835       rs200906735       rs201023018       rs201114274       rs201134410       rs201252353       rs201275097       rs201284800       rs201296788       rs201384896       rs201401823       rs201411080       rs201454153       rs201504954       rs201513541       rs201588179       rs201595671       rs201626990       rs201629347       rs201651766       rs201667384       rs201761413       rs201785095       rs201926485       rs201979490       rs202071047       rs202118545       rs202188309       rs202203985       rs367619906       rs367694827       rs367696112       rs367796430       rs367884047       rs368242561       rs368267362       rs368629956       rs368800063       rs369052751       rs369065601       rs369065936       rs369115376       rs369275074       rs369291874       rs369359524       rs369423236       rs369445995       rs369490552       rs369548668       rs369549187       rs369637146       rs369670492       rs369950735       rs370206811       rs370435354       rs370688306       rs370799186       rs370800128       rs371125319       rs371239254       rs371340046       rs371514329       rs371620929       rs371668035       rs371827672       rs372056056       rs372328393       rs372354514       rs372454555       rs372478739       rs372503245       rs372605219       rs372678429       rs372841304       rs372953110       rs373073794       rs373239302       rs373299038       rs373336006       rs373367667       rs373471296       rs373686049       rs373710578       rs373759108       rs373825952       rs374584872       rs374596343       rs374616149       rs374866452       rs374921310       rs375086019       rs375229073       rs375461558       rs375565424       rs375616926       rs375632921       rs375716818       rs375785782       rs375892770       rs375895746       rs375906123       rs376002725       rs376188991       rs376222750       rs376338646       rs376492290       rs376505927       rs376683020       rs376760285       rs376945199       rs377334359       rs377558621       rs377625664       rs397828969       rs527518989       rs527555576       rs528121779       rs528174405       rs528308035       rs528337188       rs528515982       rs528650998       rs528745380       rs528782445       rs528914256       rs529099903       rs529135631       rs529500612       rs529535744       rs529624757       rs529702253       rs529740325       rs529788073       rs529836450       rs530278822       rs530314240       rs530525411       rs530550086       rs530589224       rs530624618       rs530775146       rs531567474       rs531605057       rs531784626       rs531822722       rs532199877       rs532392071       rs532543805       rs532576541       rs532616279       rs532817981       rs532953601       rs532990017       rs532991608       rs533024782       rs533212886       rs533222150       rs533413700       rs533443633       rs533727888       rs533969034       rs533978507       rs534349930       rs534377903       rs534413116       rs534456604       rs534715459       rs534877827       rs534895051       rs535103392       rs535139727       rs535150796       rs535289943       rs535380389       rs535538803       rs536047035       rs536051630       rs536053097       rs536108661       rs536127598       rs536166302       rs536358779       rs536466093       rs536648531       rs536685603       rs536905714       rs537042341       rs537075565       rs537116781       rs537117160       rs537638583       rs537676968       rs537694515       rs537958733       rs538040033       rs538071766       rs538108687       rs538145408       rs538287293       rs538792534       rs538817149       rs538854128       rs539025816       rs539042964       rs539052584       rs539062470       rs539242876       rs539283515       rs539359617       rs539532219       rs539612881       rs539641925       rs539863229       rs540071852       rs540094013       rs540108020       rs540201451       rs540238320       rs540523008       rs540637420       rs540696411       rs540773217       rs540800562       rs540831958       rs540969252       rs541010921       rs541044711       rs541048181       rs541082997       rs541470235       rs541491854       rs541634565       rs542230577       rs542435661       rs542442232       rs542478989       rs542514092       rs542649737       rs542821175       rs542858679       rs543051975       rs543139466       rs543239464       rs543271003       rs543407608       rs543444609       rs543486172       rs543810282       rs543869107       rs544181418       rs544219990       rs544416992       rs544454375       rs544463252       rs544465722       rs544489610       rs544502467       rs544740138       rs544777358       rs545024531       rs545165633       rs545202355       rs545207129       rs545243892       rs545254937       rs545294565       rs545536872       rs545808888       rs545816233       rs546113694       rs546278616       rs546298247       rs546413440       rs546483601       rs546633916       rs546820384       rs546859130       rs546938751       rs546946042       rs546984859       rs547081472       rs547118668       rs547157177       rs547188747       rs547280311       rs547417310       rs547712436       rs547750895       rs547758247       rs547907992       rs547946611       rs548086268       rs548328934       rs548503312       rs548578922       rs548702993       rs548778884       rs548816854       rs548965143       rs549095564       rs549134286       rs549512152       rs549522924       rs549551015       rs549587512       rs549693147       rs550079098       rs550146046       rs550359905       rs550582492       rs550582547       rs550700049       rs550707915       rs550748870       rs550822871       rs550842774       rs550917615       rs551078700       rs551094285       rs551304737       rs551379718       rs551413475       rs551416570       rs551504393       rs551504500       rs551534186       rs551614857       rs551696685       rs552008353       rs552550647       rs552561825       rs552585892       rs552625384       rs553092610       rs553157185       rs553295911       rs553323478       rs553360168       rs553630349       rs553667065       rs553898626       rs553938729       rs554081308       rs554375420       rs554414256       rs554638193       rs554770219       rs554907629       rs554909036       rs554955903       rs555081901       rs555118217       rs555273248       rs555307665       rs555434010       rs555649966       rs555711679       rs555713612       rs555860385       rs555894906       rs556035181       rs556137078       rs556634641       rs556658235       rs556806089       rs556899226       rs556936029       rs556945064       rs557039283       rs557070773       rs557250179       rs557700179       rs557717541       rs557737103       rs557754133       rs558052905       rs558089587       rs558152830       rs558276287       rs558796097       rs558858247       rs558859839       rs558940184       rs558983602       rs559080746       rs559226975       rs559252845       rs559291767       rs559302245       rs559469073       rs559523990       rs559865075       rs560238901       rs560244653       rs560415481       rs560452456       rs560471709       rs560481078       rs560567470       rs560600725       rs560708317       rs560791425       rs560956827       rs560993681       rs561030033       rs561239729       rs561242799       rs561307345       rs561348142       rs561496513       rs561617190       rs561830356       rs562032185       rs562156871       rs562230506       rs562514957       rs562617404       rs562654158       rs562959223       rs562996399       rs562996440       rs563271621       rs563290970       rs563987726       rs564028222       rs564037013       rs564037375       rs564479565       rs564515805       rs564601200       rs564943126       rs565008371       rs565029841       rs565045832       rs565064895       rs565225961       rs565274100       rs565467396       rs565627701       rs565635480       rs565669734       rs565763900       rs565823520       rs565855433       rs566098219       rs566225577       rs566397777       rs566409909       rs566721769       rs566834246       rs566954750       rs566988863       rs567224769       rs567226576       rs567361176       rs567402501       rs567439299       rs567475714       rs567536421       rs567594465       rs567835972       rs568119792       rs568205682       rs568339141       rs568752342       rs568865590       rs569109915       rs569115150       rs569188748       rs569226968       rs569308746       rs569362974       rs569390919       rs569428180       rs569430159       rs569466822       rs569631939       rs569677878       rs569804096       rs569878605       rs570138747       rs570195744       rs570198339       rs570232345       rs570271096       rs570274022       rs570379497       rs570441595       rs570474824       rs570690730       rs571137849       rs571253469       rs571291813       rs571307399       rs571457503       rs571589912       rs571667250       rs571691538       rs571691748       rs571718614       rs571836582       rs571933768       rs572435070       rs572468576       rs572487507       rs572631841       rs572774596       rs572801991       rs572947894       rs572984210       rs573165592       rs573202541       rs573204302       rs573657050       rs573789752       rs573799326       rs573901258       rs574001617       rs574139716       rs574394671       rs574433261       rs574456396       rs574497656       rs574714784       rs574814896       rs575025354       rs575051357       rs575062231       rs575379740       rs575395084       rs575537931       rs575551262       rs575587594       rs575672737       rs575711833       rs575739809       rs575824695       rs575853146       rs575895469       rs576425384       rs576428080       rs576593920       rs576656066       rs576802823       rs576826415       rs576839585       rs576896312       rs576924765       rs577441833       rs577551022       rs577589609       rs577653336       rs577694556       rs577818278       rs577869411       rs578000381       rs578045340       rs578087240       rs745320926       rs745320934       rs745401689       rs745500485       rs745561508       rs745574934       rs745597439       rs745625413       rs745775729       rs745785368       rs745800729       rs745855820       rs745910443       rs745917375       rs746101394       rs746260182       rs746344283       rs746358807       rs746460883       rs746592332       rs746645555       rs746676138       rs746736617       rs746826563       rs746853919       rs746928258       rs746973453       rs747041691       rs747062489       rs747179714       rs747208610       rs747335393       rs747513493       rs747527740       rs747546513       rs747572279       rs747758397       rs747797842       rs747816297       rs747822893       rs747986527       rs748007362       rs748069287       rs748155312       rs748287281       rs748406023       rs748410299       rs748427915       rs748458215       rs748666159       rs748700376       rs748705274       rs748758418       rs748898711       rs748950749       rs749227033       rs749251478       rs749301688       rs749321294       rs749391241       rs749429353       rs749567933       rs749571211       rs749583814       rs749735500       rs749768363       rs749807503       rs749874453       rs749997388       rs750001060       rs750129533       rs750132680       rs750377658       rs750568989       rs750630766       rs750635579       rs750674495       rs750831409       rs750868168       rs750959859       rs751021787       rs751130639       rs751139614       rs751238865       rs751306189       rs751485824       rs751504204       rs751504540       rs751511911       rs751606380       rs751634562       rs751639344       rs751642339       rs751732779       rs751845399       rs751914213       rs752003230       rs752006218       rs752007713       rs752095846       rs752212816       rs752289634       rs752290942       rs752345580       rs752407430       rs752410339       rs752487350       rs752574389       rs752664371       rs752737141       rs752740412       rs752754669       rs752777359       rs752853088       rs752952955       rs753018012       rs753066478       rs753159835       rs753167841       rs753345110       rs753452540       rs753462056       rs753543119       rs753616096       rs753750139       rs753807140       rs753911974       rs754017953       rs754030751       rs754055777       rs754062358       rs754142725       rs754142778       rs754157196       rs754289228       rs754351359       rs754379244       rs754521111       rs754543432       rs754596945       rs754675231       rs754801668       rs754817289       rs754835809       rs754942104       rs755014262       rs755016196       rs755026890       rs755139103       rs755272851       rs755283417       rs755358029       rs755549279       rs755568378       rs755766002       rs755834976       rs755853960       rs755925144       rs755933780       rs756196014       rs756212278       rs756267847       rs756297296       rs756458516       rs756472808       rs756473118       rs756726784       rs756857261       rs756910349       rs756927336       rs757033244       rs757065734       rs757170144       rs757179081       rs757338979       rs757433060       rs757528864       rs757557427       rs757609204       rs757847381       rs757911740       rs758003588       rs758131778       rs758187019       rs758219709       rs758241431       rs758331193       rs758365551       rs758409152       rs758489543       rs758691394       rs758711292       rs758785257       rs759073455       rs759157392       rs759279462       rs759281170       rs759293208       rs759447836       rs759451691       rs759676949       rs759768731       rs759839385       rs759916853       rs759967581       rs760009468       rs760019625       rs760035149       rs760192233       rs760386646       rs760448223       rs760449660       rs760574084       rs760618310       rs760720434       rs760783451       rs760821576       rs760843262       rs760910930       rs761011357       rs761047831       rs761061137       rs761078344       rs761207382       rs761346163       rs761472771       rs761622248       rs761658961       rs761662303       rs761731760       rs761775892       rs761821081       rs761906572       rs761970635       rs761999512       rs762013300       rs762092212       rs762103647       rs762202186       rs762217022       rs762274382       rs762323976       rs762371270       rs762402251       rs762468597       rs762496809       rs762674045       rs762678794       rs762944846       rs763113629       rs763144999       rs763206894       rs763283811       rs763308508       rs763417495       rs763490029       rs763495034       rs763595033       rs763679201       rs763734322       rs763759222       rs763795833       rs763874610       rs763943164       rs763987841       rs764103599       rs764199648       rs764203427       rs764241201       rs764287601       rs764369782       rs764507046       rs764540300       rs764549857       rs764624712       rs764712803       rs764735588       rs764808250       rs764897822       rs764932785       rs764939554       rs765042027       rs765080448       rs765312151       rs765353615       rs765400731       rs765428678       rs765522836       rs765551072       rs765601586       rs765683731       rs765683826       rs765725346       rs765775694       rs765865152       rs765948288       rs765959682       rs766083673       rs766263099       rs766265250       rs766265690       rs766386368       rs766459090       rs766461745       rs766471766       rs766479772       rs766545427       rs766583746       rs766723775       rs766825981       rs766916228       rs766933898       rs766952372       rs767011786       rs767070095       rs767127721       rs767273492       rs767297801       rs767394233       rs767396501       rs767590579       rs767683152       rs767715828       rs767769934       rs767786395       rs767809545       rs767914638       rs767936575       rs767969883       rs768000977       rs768095286       rs768121368       rs768136984       rs768140632       rs768354997       rs768565965       rs768582281       rs768586662       rs768647382       rs768687717       rs768708805       rs768808412       rs768857247       rs768983375       rs769065945       rs769186196       rs769195294       rs769291085       rs769317206       rs769333660       rs769412356       rs769491316       rs769520780       rs769708564       rs769709328       rs769758225       rs769822838       rs769834103       rs769957121       rs770010930       rs770029114       rs770149663       rs770162385       rs770201277       rs770273085       rs770380431       rs770415743       rs770444106       rs770446506       rs770467584       rs770572978       rs770837527       rs770853944       rs770859507       rs770993453       rs770997318       rs771033454       rs771296922       rs771358198       rs771399185       rs771579910       rs771602494       rs771657358       rs771705054       rs771726385       rs771793196       rs771805630       rs771817374       rs771865179       rs772000136       rs772123756       rs772319665       rs772386465       rs772507310       rs772564979       rs772583299       rs772595628       rs772688836       rs772744700       rs772778879       rs772907091       rs772988569       rs773120881       rs773181111       rs773183075       rs773251097       rs773308210       rs773401054       rs773429633       rs773496807       rs773503383       rs773518946       rs773565590       rs773709600       rs773785095       rs773789074       rs773799637       rs774090351       rs774157113       rs774266781       rs774270524       rs774278124       rs774371565       rs774458075       rs774524408       rs774794252       rs774868537       rs774906598       rs774933377       rs774954512       rs774992337       rs775026815       rs775142209       rs775272924       rs775317410       rs775407001       rs775410752       rs775524967       rs775556718       rs775610916       rs775845002       rs775894319       rs775947488       rs775970225       rs775988761       rs775997601       rs776033510       rs776160224       rs776171122       rs776187970       rs776361432       rs776408704       rs776424734       rs776528997       rs776606930       rs776657408       rs776827781       rs776932054       rs776940752       rs777106761       rs777109895       rs777201978       rs777204293       rs777215776       rs777248510       rs777318809       rs777366434       rs777413319       rs777470853       rs777627903       rs777685410       rs777790549       rs777982158       rs778002286       rs778003655       rs778057476       rs778103242       rs778181359       rs778377227       rs778474910       rs778619597       rs778693644       rs778743407       rs778868424       rs778894623       rs778952844       rs779144954       rs779233922       rs779305303       rs779309364       rs779680690       rs779742465       rs779766814       rs779797707       rs779980950       rs780084938       rs780174941       rs780205575       rs780243435       rs780407201       rs780451257       rs780608767       rs780638681       rs780759190       rs780922082       rs780937047       rs781024869       rs781207682       rs781220784       rs781301047       rs781302776       rs781418401       rs781438796       rs781489462       rs781539919       rs781632238       rs781668982       rs781748952       rs869174506      

PRDM9基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TGCACTGATTACTATAGGTCTCAG
59
TCCACCTGGAGTTTGATGG
59
AGAGATGGGAGACTGGGAG
59
GGCTCTGAGACCTATAGTAATCAG
59
ATTACTATAGGTCTCAGAGCCAC
59
CTGTGTCATCCACCTGGAG
59
      尚未收录相关数据

PRDM9基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

PRDM9基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0005634
A0A0U1RQY2(UniProtKB)
IEA
GO:0006355
A0A0U1RQY2(UniProtKB)
IEA
GO:0046872
A0A0U1RQY2(UniProtKB)
IEA
GO:0003676
D6RD68(UniProtKB)
IEA
GO:0005622
D6RD68(UniProtKB)
IEA
GO:0006355
D6RD68(UniProtKB)
IEA
GO:0003676
Q9NQV7(UniProtKB)
IEA
GO:0005654
Q9NQV7(UniProtKB)
TAS
GO:0005654
Q9NQV7(UniProtKB)
TAS
GO:0005694
Q9NQV7(UniProtKB)
IEA
GO:0006311
Q9NQV7(UniProtKB)
IDA
GO:0006351
Q9NQV7(UniProtKB)
IEA
GO:0006355
Q9NQV7(UniProtKB)
IEA
GO:0010845
Q9NQV7(UniProtKB)
IMP
GO:0018024
Q9NQV7(UniProtKB)
TAS
GO:0034968
Q9NQV7(UniProtKB)
IEA
GO:0046872
Q9NQV7(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控PRDM9基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Azoospermia 0.005276948 3 2 BeFree_GAD
Male infertility 0.002638474 2 0 BeFree_GAD
Carotid Stenosis 0.002367032 1 1 GAD
Cystic kidney 0.000271442 1 0 BeFree
Trisomy 0.000271442 1 0 BeFree
Williams Syndrome 0.000271442 1 0 BeFree
Shprintzen syndrome 0.000271442 1 0 BeFree
Leukemogenesis 0.000271442 1 0 BeFree
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