PRB1(proline-rich protein BstNI subfamily 1) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

12p13.2
基因染色体位置图

基因简述

基因简述

This gene encodes a precursor for proline-rich salivary proteins. This and five other genes that encode salivary proline-rich proteins (PRPs)form a PRP gene cluster in the chromosomal 12p13 region. Precursor salivary PRPs are cleaved multiple times to produce a diversity of secreted peptides. Alleles of this gene exhibit tandem repeat length variation in the coding region as well as polymorphic cleavage sites and polymorphic stop codons. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基??因编码的富含脯氨酸的唾液蛋白的前体。这和编码唾液富含脯氨酸的蛋白质（富脯氨酸多肽）五，其他基因构成的染色体12p13区的PRP基因簇。前体唾液的PRPs被切割多次，以产生分泌肽的多样性。在编码区该基因表现出串联重复长度变化的等位基因以及多态性切割位点和多形终止密码子。在多个转录剪接变异体结果不同编码的亚型。 [由RefSeq的，2008年7月提供]

OMIM数据库中对PRB1基因的介绍     Wikipedia数据库中对PRB1基因的介绍

基因序列

基因序列

PRB1基因的碱基序列：[NCBI]

基因突变

基因突变

PRB1基因的碱基突变：           显示全部snp
rs1820608       rs116516983       rs143710656       rs146061369       rs181483834       rs182379444       rs185783723       rs189001327       rs190054865       rs527595140       rs528094571       rs531652099       rs531710604       rs535961025       rs538618984       rs540528934       rs543111077       rs543173283       rs554424093       rs558214094       rs559185066       rs574258596       rs762588       rs1820606       rs1820607       rs1863847       rs1882252       rs1882253       rs2272509       rs2416557       rs3759239       rs3867481       rs3867483       rs3983889       rs3983890       rs4081837       rs4533125      
rs7487796       rs10459058       rs10772451       rs10772452       rs10845341       rs11054265       rs11054266       rs11054267       rs11612458       rs17846367       rs55930793       rs56122235       rs61930107       rs61930108       rs61930109       rs72477471       rs74903687       rs76504934       rs78082688       rs80287272       rs111543911       rs111602128       rs111828784       rs111877208       rs111877867       rs112485268       rs112499228       rs112522723       rs112850606       rs112967625       rs113277863       rs113485215       rs113518684       rs113615594       rs113678218       rs113897264       rs114069696       rs114907226       rs115240812       rs116895189       rs137972987       rs139243564       rs139398946       rs140102760       rs140334146       rs140825288       rs141076827       rs141106766       rs141114988       rs141582973       rs142230638       rs142774972       rs142882443       rs143025184       rs144071415       rs144282801       rs144572980       rs144687469       rs144693892       rs144833264       rs144917793       rs145243462       rs146712376       rs148177558       rs148178581       rs149040356       rs149411690       rs149993046       rs150307615       rs150817243       rs151229325       rs181739158       rs181997933       rs182585818       rs182702380       rs183317251       rs183794773       rs183921883       rs184270808       rs185436108       rs186922966       rs187276482       rs188067455       rs188424672       rs188652051       rs189614237       rs189908911       rs190423668       rs190432218       rs190530334       rs191378872       rs191645291       rs191800565       rs192597161       rs199533329       rs199560403       rs199575480       rs199583161       rs199707822       rs199753072       rs199764037       rs199796307       rs200021729       rs200040043       rs200080540       rs200283098       rs200689268       rs200708213       rs200763018       rs200893556       rs200997903       rs201055825       rs201306426       rs201400496       rs201593462       rs201615726       rs201682460       rs201751674       rs201872688       rs201908587       rs201910051       rs201935302       rs202014168       rs202083397       rs367559123       rs368730404       rs368738842       rs368788370       rs369001998       rs369169524       rs369194907       rs369472318       rs369585183       rs370084280       rs370553680       rs370601533       rs371206768       rs371435593       rs371758892       rs371841290       rs371946641       rs372010024       rs372368931       rs372417210       rs372620668       rs372966668       rs373764594       rs374203325       rs374273726       rs374294604       rs374362968       rs374516099       rs374843401       rs374894550       rs375239178       rs377139888       rs377208399       rs377307645       rs377466790       rs377685305       rs377735593       rs527663469       rs527724053       rs528732224       rs529377307       rs529885098       rs530566644       rs530631129       rs530990598       rs531053386       rs531114875       rs532216824       rs533060930       rs533280011       rs533327314       rs533388064       rs534597111       rs534888686       rs535465126       rs535767592       rs535833900       rs535886414       rs536429551       rs537167581       rs538028710       rs538092284       rs538155812       rs538156137       rs538359627       rs538916421       rs539330997       rs539435682       rs539495859       rs539846705       rs539873857       rs540041950       rs540346113       rs540589956       rs542147129       rs542208422       rs542249584       rs542662358       rs543236962       rs543296405       rs544290443       rs544594247       rs545542007       rs545607485       rs545741478       rs546101836       rs547636346       rs547944212       rs548104014       rs548439937       rs549338107       rs549400155       rs549421413       rs550535330       rs550597046       rs550697149       rs550759578       rs550761198       rs550826919       rs551625947       rs551796379       rs552348584       rs552564165       rs552972230       rs553630020       rs553689169       rs553812852       rs553874165       rs554211998       rs554685067       rs554742853       rs555612549       rs555671248       rs555677892       rs555754338       rs555881001       rs556805944       rs557007437       rs557068661       rs557678376       rs557880435       rs558057993       rs558136165       rs558201329       rs559238595       rs559972767       rs560111980       rs560621383       rs560820246       rs561035841       rs561811755       rs562031108       rs562092491       rs562452652       rs563021727       rs563229061       rs564154075       rs564649745       rs565153511       rs565362752       rs565569312       rs565759890       rs566289482       rs566780388       rs566822408       rs566841270       rs566886402       rs567022182       rs567376506       rs567542463       rs567922950       rs568340821       rs568645635       rs568661757       rs569168761       rs569232210       rs569236146       rs569534909       rs570732294       rs570853082       rs571381613       rs571972247       rs572511339       rs573028438       rs573055528       rs573274364       rs573652448       rs573740236       rs574187841       rs574275890       rs574462051       rs574525404       rs574591034       rs575539999       rs575543081       rs575602928       rs575604165       rs575666387       rs575728881       rs576051236       rs576676373       rs576791893       rs577733867       rs577880107       rs745461617       rs745546262       rs745726339       rs745818003       rs745916968       rs746014968       rs746024628       rs746333846       rs746480633       rs746633025       rs746865717       rs746967703       rs747061786       rs747151388       rs747178726       rs747402616       rs747444571       rs747592781       rs747628015       rs747668355       rs747872164       rs748050772       rs748244889       rs748303563       rs748391433       rs748523335       rs748528437       rs748871632       rs749004520       rs749176107       rs749305426       rs749363402       rs749428874       rs749451120       rs749660835       rs749743546       rs749837140       rs749907834       rs749997928       rs750282932       rs750393926       rs750538709       rs750601108       rs750607865       rs750628459       rs750789699       rs751161636       rs751444505       rs751481346       rs751733988       rs751749008       rs751826141       rs752003437       rs752060356       rs752621387       rs752815364       rs753075919       rs753193107       rs753376318       rs753386134       rs753509002       rs753558173       rs753846216       rs753884425       rs754021401       rs754101518       rs754332219       rs754442633       rs754665084       rs754707370       rs754824687       rs755037629       rs755056048       rs755243998       rs755366986       rs755588850       rs755594068       rs755605576       rs755622101       rs755816095       rs755857717       rs755939023       rs756052763       rs756246798       rs756354749       rs756549084       rs756768771       rs756918698       rs757120487       rs757316550       rs757350524       rs757376772       rs757541752       rs757589454       rs757632626       rs757818406       rs758261250       rs758488252       rs758599141       rs759072283       rs759298496       rs759344695       rs759422959       rs759508893       rs759804295       rs759946986       rs759996323       rs760247453       rs760399871       rs760529729       rs760701009       rs760897822       rs761005494       rs761049074       rs761131883       rs761467086       rs761505683       rs761668034       rs761701658       rs761770169       rs762134116       rs762141654       rs762221793       rs762525252       rs762562204       rs762585075       rs762647749       rs762701306       rs762851117       rs762910991       rs762960285       rs763293968       rs763386169       rs763458022       rs763495409       rs763805826       rs763820742       rs763877371       rs763929141       rs763993754       rs764083371       rs764168809       rs764285677       rs764372329       rs764586271       rs764675824       rs764997940       rs765049064       rs765262326       rs765538157       rs765573970       rs765759002       rs765833426       rs765836302       rs766131639       rs766408449       rs766800898       rs766953701       rs766979126       rs767343899       rs767363136       rs767418952       rs767481139       rs767813421       rs767814028       rs767918809       rs768210988       rs768233652       rs768365355       rs768450843       rs768602512       rs768953014       rs768961671       rs769030402       rs769220704       rs769303072       rs769369069       rs769508602       rs769700610       rs769793379       rs769971419       rs770020969       rs770117345       rs770529845       rs770537652       rs770612970       rs770656340       rs770768377       rs770846601       rs771078391       rs771168617       rs771189865       rs771241473       rs771333797       rs771386093       rs771648794       rs772066807       rs772087758       rs772221403       rs772309208       rs772365043       rs772458449       rs772600553       rs772740512       rs772744501       rs772801999       rs773002860       rs773277650       rs773391031       rs773465432       rs773516265       rs773578589       rs773714373       rs773762971       rs773775190       rs774049620       rs774051539       rs774152887       rs774158904       rs774176071       rs774179782       rs774430710       rs774541637       rs774645761       rs774775980       rs774862229       rs774914387       rs775176455       rs775294830       rs775301681       rs775396271       rs775414263       rs775432933       rs775586646       rs775782949       rs776135514       rs776461033       rs776582994       rs776710424       rs776770565       rs776807117       rs776999775       rs777003286       rs777194470       rs777212447       rs777321074       rs777674153       rs777766549       rs777839431       rs777854193       rs777944854       rs778399720       rs778532670       rs778720909       rs779093910       rs779122623       rs779672959       rs779691641       rs779946601       rs780009220       rs780096070       rs780717543       rs780720498       rs781088878       rs781248438       rs781339792       rs781440647       rs781485880      

基因表达

基因表达

PRB1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TTGATTCTGCTGTCAGTGG
58
TGTGGATTTCCTGCTATTAGG
58
TTGATTCTGCTGTCAGTGG
58
TGTGGATTTCCTGCTATTAGG
58
TTGATTCTGCTGTCAGTGG
58
GTGGATTTCCTGCTATTAGGG
58
GTTGATTCTGCTGTCAGTGG
59
GTGGATTTCCTGCTATTAGGG
58
TTGATTCTGCTGTCAGTGG
58
GTGGATTTCCTGCTATTAGGG
58
TTGATTCTGCTGTCAGTGG
58
TGTGGATTTCCTGCTATTAGG
58
GTTGATTCTGCTGTCAGTGG
59
GTGGATTTCCTGCTATTAGGG
58
GTTGATTCTGCTGTCAGTGG
59
GTGGATTTCCTGCTATTAGGG
58
TTGATTCTGCTGTCAGTGG
58
TGTGGATTTCCTGCTATTAGG
58
TTGATTCTGCTGTCAGTGG
58
GTGGATTTCCTGCTATTAGGG
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

PRB1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

PRB1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0003674
P04280(UniProtKB)
ND
GO:0005576
P04280(UniProtKB)
IEA
GO:0008150
P04280(UniProtKB)
ND

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控PRB1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Primary Myelofibrosis 0.000814326 3 0 BeFree
Exanthema 0.000814326 3 0 BeFree
Polycythemia Vera 0.000814326 3 2 BeFree
Spots on skin 0.000814326 3 0 BeFree
Myeloproliferative disease 0.000542884 2 2 BeFree
Chronic myeloproliferative disorder 0.000542884 2 2 BeFree
Malignant tumor of colon 0.000271442 1 0 BeFree
HIV Infections 0.000271442 1 0 BeFree
Acute Megakaryocytic Leukemias 0.000271442 1 0 BeFree
Lymphoma 0.000271442 1 0 BeFree
Myelofibrosis 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Retinoblastoma 0.000271442 1 0 BeFree
Thrombocythemia, Essential 0.000271442 1 0 BeFree
Unipolar Depression 0.000271442 1 0 BeFree
Malignant neoplasm of colon stage IV 0.000271442 1 0 BeFree
Acute panmyelosis with myelofibrosis 0.000271442 1 0 BeFree
Endometrial Carcinoma 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Colon Carcinoma 0.000271442 1 0 BeFree
Major Depressive Disorder 0.000271442 1 0 BeFree
Hereditary Nonpolyposis Colorectal Cancer 0.000271442 1 0 BeFree
NEUROTICISM 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

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