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The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
[中文简述(自动翻译):]  由该基因编码的蛋白质是POU结构域家族的含同源异型框的转录因子。所编码的蛋白质结合的八聚体序列5‘-ATTTGCAT-3‘,在免疫球蛋白基因启动子共同的转录因子结合位点。已发现该基因编码不同亚型的几个抄本变形。 [由RefSeq的,2011年10月提供]
POU2F2基因(以及对应的蛋白质)的细胞分布位置:
POU2F2基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Peripheral Neuropathy | 0.12 | 1 | 0 | CTD_human |
| Hodgkin Disease | 0.003267234 | 2 | 0 | BeFree_LHGDN |
| Burkitt Lymphoma | 0.002995792 | 2 | 0 | BeFree_LHGDN |
| Kidney Diseases | 0.002367032 | 1 | 0 | GAD |
| B-Cell Lymphomas | 0.001085767 | 4 | 0 | BeFree |
| Classical Hodgkin's Lymphoma | 0.001085767 | 4 | 0 | BeFree |
| Leukemia, Myelocytic, Acute | 0.000814326 | 3 | 0 | BeFree |
| Pituitary Diseases | 0.000814326 | 3 | 0 | BeFree |
| Colorectal Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Lymphoma | 0.000542884 | 2 | 0 | BeFree |
| Multiple Myeloma | 0.000542884 | 2 | 0 | BeFree |
| Carcinogenesis | 0.000542884 | 2 | 0 | BeFree |
| Primary Effusion Lymphoma | 0.000542884 | 2 | 0 | BeFree |
| Liver carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of breast | 0.000271442 | 1 | 0 | BeFree |
| Malignant tumor of cervix | 0.000271442 | 1 | 0 | BeFree |
| Choriocarcinoma | 0.000271442 | 1 | 0 | BeFree |
| leukemia | 0.000271442 | 1 | 0 | BeFree |
| Leukemia, T-Cell | 0.000271442 | 1 | 0 | BeFree |
| Lymphoma, Follicular | 0.000271442 | 1 | 0 | BeFree |
| Waldenstrom Macroglobulinemia | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of stomach | 0.000271442 | 1 | 0 | BeFree |
| melanoma | 0.000271442 | 1 | 0 | BeFree |
| Neoplasm Metastasis | 0.000271442 | 1 | 0 | BeFree |
| Nephroblastoma | 0.000271442 | 1 | 0 | BeFree |
| Obesity | 0.000271442 | 1 | 0 | BeFree |
| Pericardial effusion | 0.000271442 | 1 | 0 | BeFree |
| Kidney Failure | 0.000271442 | 1 | 0 | BeFree |
| Rhabdomyosarcoma | 0.000271442 | 1 | 0 | BeFree |
| Congenital heart disease | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of gallbladder | 0.000271442 | 1 | 0 | BeFree |
| Hodgkin's-like | 0.000271442 | 1 | 0 | BeFree |
| Pancreatic carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Cervix carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of pancreas | 0.000271442 | 1 | 0 | BeFree |
| Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Secondary malignant neoplasm of lymph node | 0.000271442 | 1 | 0 | BeFree |
| Stomach Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Metastatic Prostate Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Sarcoma | 0.000271442 | 1 | 0 | BeFree |
| Nodular Lymphocyte Predominant Hodgkin Lymphoma | 0.000271442 | 1 | 0 | BeFree |
| Renal Insufficiency | 0.000271442 | 1 | 0 | BeFree |
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