POLD4(polymerase (DNA-directed), delta 4, accessory subunit)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

11q13
基因染色体位置图

基因简述

基因简述

This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]

[中文简述(自动翻译):]  该基因编码DNA聚合酶三角洲的最小亚基。的DNA聚合酶δ具有既聚合酶和3‘至5‘外切酶活性和在DNA复制和修复的关键作用。所编码的蛋白质增强的DNA聚合酶δ的活性和播放通过与DNA螺旋Bloom综合征蛋白质相互作用在叉修理和稳定的作用。编码多种亚型选择性剪接的转录物变体已经观察到这种基因。 [由RefSeq的，2012年3月提供]

OMIM数据库中对POLD4基因的介绍     Wikipedia数据库中对POLD4基因的介绍

基因序列

基因序列

POLD4基因的碱基序列：[NCBI]

基因突变

基因突变

POLD4基因的碱基突变：           显示全部snp
rs6560       rs1051107       rs1051120       rs1051123       rs1790731       rs1790735       rs2511057       rs2514257       rs2514258       rs7951732       rs11227777       rs11227778       rs11822387       rs11822467       rs28364235       rs28364236       rs28364237       rs28364238       rs28364239       rs28364240       rs28364241       rs28364242       rs28364243       rs28364244       rs28364245       rs28364246       rs28364247       rs28364248       rs28364249       rs28364250       rs28364251       rs28364252       rs28364253       rs34136263       rs34351407       rs58088599       rs71461641      
rs113390818       rs113752615       rs138101947       rs138779527       rs140664272       rs141546876       rs141547365       rs143787057       rs144461034       rs145139085       rs145225786       rs145414845       rs145957405       rs146861904       rs149452980       rs150367541       rs150889244       rs181053445       rs181342592       rs183043767       rs183809213       rs184493278       rs185406485       rs185433644       rs185507990       rs185936511       rs186868681       rs187034032       rs187535710       rs188319085       rs188928496       rs189077848       rs190811406       rs191101107       rs191985695       rs193266776       rs199992452       rs200868910       rs201016876       rs201564577       rs369187744       rs369198970       rs369415579       rs369947012       rs370308033       rs370751897       rs371109758       rs371468798       rs371931081       rs372399224       rs372510404       rs372657387       rs373063436       rs373326249       rs374392163       rs375234486       rs375267187       rs375713711       rs377194279       rs527546926       rs527654656       rs529379309       rs529893518       rs529974608       rs531081760       rs531146126       rs531618182       rs531710707       rs532188328       rs533433787       rs533541045       rs533986090       rs535119715       rs536043506       rs536071668       rs536102872       rs536237859       rs537487597       rs538038516       rs538907534       rs540094168       rs540456424       rs541410851       rs541462987       rs541538039       rs541647849       rs543723815       rs543999718       rs544257396       rs544835735       rs545507858       rs545651920       rs546850108       rs547917428       rs547977451       rs548989822       rs549402830       rs549619826       rs549652687       rs549942256       rs550246173       rs552186021       rs554917197       rs555849556       rs556384907       rs556682842       rs557231759       rs557641393       rs558179508       rs558561584       rs558620559       rs558632895       rs559873172       rs559886233       rs559936414       rs561888507       rs562129775       rs562488135       rs563016267       rs563234246       rs563686095       rs564391561       rs564959795       rs565471728       rs566238226       rs566301222       rs567399581       rs568489545       rs568975079       rs569501244       rs570127081       rs570277669       rs570771947       rs571483265       rs573079999       rs574077245       rs574114733       rs574480007       rs574955602       rs575541121       rs576190279       rs576767423       rs577010898       rs745371682       rs746081123       rs747518956       rs747903396       rs748518077       rs748607722       rs748993149       rs749142710       rs749337687       rs749525237       rs749664496       rs750048961       rs750239946       rs750725004       rs751610453       rs751903034       rs752087456       rs752172692       rs753489289       rs753501226       rs753879282       rs754055454       rs754485355       rs754788876       rs755797510       rs755906023       rs756220551       rs757590272       rs757680383       rs758740392       rs759175252       rs759268188       rs759817626       rs760265088       rs760434696       rs761303603       rs761656531       rs761822208       rs762487284       rs762923883       rs764551741       rs764671311       rs766041070       rs766060175       rs766174297       rs766436446       rs767067049       rs767428061       rs767478794       rs768662897       rs769037166       rs769491961       rs769580420       rs769846621       rs769933735       rs770074383       rs770442598       rs770835542       rs771361847       rs771932144       rs772492719       rs772582490       rs772643660       rs772733554       rs772903143       rs774335205       rs774791582       rs774821095       rs775264611       rs775354650       rs775727738       rs776034868       rs776494044       rs776969995       rs776979039       rs777656884       rs778149868       rs778239887       rs778296106       rs778905177       rs779104220       rs779192794       rs779594503       rs780280311       rs780314719       rs780693051       rs781368702       rs781460436       rs781685267      

基因表达

基因表达

POLD4基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ATCACTGATTCCTACCCGG
59
ATAGAGATGCCAGAGACTGC
59
GGTTGTGAAGAGGAGGGAG
59
TAGAGATGCCAGAGACTGC
59
AAAGAATTCTGGCCCACAG
58
ATAGAGATGCCAGAGACTGC
59
AAAGAATTCTGGCCCACAG
58
TAGAGATGCCAGAGACTGC
59
AGTCTCTGGCATCTCTATCC
58
CTGTCCTGAGGTTCTTGGG
60
CATCACTGATTCCTACCCG
57
ATAGAGATGCCAGAGACTGC
59
GTCTCTGGCATCTCTATCCC
59
TCTGTCCTGAGGTTCTTGG
59
GAGGGAGAAATGGATGGAG
57
CCTCATAGAATCTTCTTGCCT
57
GGTTGTGAAGAGGAGGGAG
59
TGACTTCAGAGACGTGTGG
59
GAGGGAGAAATGGATGGAG
57
CCTCATAGAATCTTCTTGCCTG
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

POLD4基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

POLD4基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000722
Q9HCU8(UniProtKB)
TAS
GO:0000722
Q9HCU8(UniProtKB)
TAS
GO:0000722
Q9HCU8(UniProtKB)
TAS
GO:0000722
Q9HCU8(UniProtKB)
TAS
GO:0000722
Q9HCU8(UniProtKB)
TAS
GO:0000722
Q9HCU8(UniProtKB)
TAS
GO:0000722
Q9HCU8(UniProtKB)
TAS
GO:0000722
Q9HCU8(UniProtKB)
TAS
GO:0000723
Q9HCU8(UniProtKB)
TAS
GO:0000731
Q9HCU8(UniProtKB)
IBA
GO:0003887
Q9HCU8(UniProtKB)
TAS
GO:0003887
Q9HCU8(UniProtKB)
TAS
GO:0003887
Q9HCU8(UniProtKB)
TAS
GO:0003887
Q9HCU8(UniProtKB)
TAS
GO:0005515
Q9HCU8(UniProtKB)
IPI
GO:0005515
Q9HCU8(UniProtKB)
IPI
GO:0005515
Q9HCU8(UniProtKB)
IPI
GO:0005515
Q9HCU8(UniProtKB)
IPI
GO:0005515
Q9HCU8(UniProtKB)
IPI
GO:0005515
Q9HCU8(UniProtKB)
IPI
GO:0005515
Q9HCU8(UniProtKB)
IPI
GO:0005634
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0005654
Q9HCU8(UniProtKB)
TAS
GO:0006260
Q9HCU8(UniProtKB)
TAS
GO:0006261
Q9HCU8(UniProtKB)
IBA
GO:0006271
Q9HCU8(UniProtKB)
TAS
GO:0006283
Q9HCU8(UniProtKB)
TAS
GO:0006296
Q9HCU8(UniProtKB)
TAS
GO:0006297
Q9HCU8(UniProtKB)
TAS
GO:0006298
Q9HCU8(UniProtKB)
TAS
GO:0006298
Q9HCU8(UniProtKB)
TAS
GO:0019985
Q9HCU8(UniProtKB)
TAS
GO:0033683
Q9HCU8(UniProtKB)
TAS
GO:0042769
Q9HCU8(UniProtKB)
TAS
GO:0043625
Q9HCU8(UniProtKB)
IBA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控POLD4基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Bloom Syndrome 0.00272435 1 0 LHGDN
Carcinogenesis 0.001085767 4 0 BeFree
Osteosarcoma 0.000814326 3 0 BeFree
Osteosarcoma of bone 0.000814326 3 0 BeFree
Glioma 0.000542884 2 0 BeFree
Adult T-Cell Lymphoma/Leukemia 0.000542884 2 0 BeFree
Retinal Diseases 0.000542884 2 0 BeFree
Malignant neoplasm of lung 0.000542884 2 0 BeFree
Carcinoma of lung 0.000542884 2 0 BeFree
Cystic Fibrosis 0.000271442 1 0 BeFree
leukemia 0.000271442 1 0 BeFree
Leukemia, Myelocytic, Acute 0.000271442 1 0 BeFree
Malaria 0.000271442 1 0 BeFree
Otitis Media 0.000271442 1 0 BeFree
Peripheral Neuropathy 0.000271442 1 0 BeFree
Small cell carcinoma of lung 0.000271442 1 0 BeFree
Gasping for breath 0.000271442 1 0 BeFree
Abnormal breathing 0.000271442 1 0 BeFree
Precursor B-cell lymphoblastic leukemia 0.000271442 1 0 BeFree
Mammary Neoplasms 0.000271442 1 0 BeFree
Infectious Otitis Media 0.000271442 1 0 BeFree

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