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This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
[中文简述(自动翻译):]  该基因编码的磷酸肌醇磷脂酶C测试酶家族催化生产在G蛋白偶联受体介导的信号转导的第二信使二酰基甘油和1,4,5-三磷酸肌醇从磷脂的成员。选择性剪接结果在多个抄本变形。[由RefSeq的,2010年5月提供]
PLCB3基因(以及对应的蛋白质)的细胞分布位置:
PLCB3基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Diabetes Mellitus, Experimental | 0.08 | 1 | 0 | RGD |
Myocardial Infarction | 0.08 | 1 | 0 | RGD |
Inflammation | 0.00272435 | 1 | 0 | LHGDN |
HIV Infections | 0.002367032 | 1 | 0 | GAD |
Attention deficit hyperactivity disorder | 0.002367032 | 1 | 1 | GAD |
Carcinogenesis | 0.001085767 | 4 | 0 | BeFree |
Multiple Endocrine Neoplasia Type 1 | 0.000542884 | 2 | 0 | BeFree |
Neuroendocrine Tumors | 0.000542884 | 2 | 0 | BeFree |
Dermatitis | 0.000271442 | 1 | 0 | BeFree |
Dermatitis, Atopic | 0.000271442 | 1 | 0 | BeFree |
Eczema | 0.000271442 | 1 | 0 | BeFree |
Hyperparathyroidism | 0.000271442 | 1 | 0 | BeFree |
Islet Cell Tumor | 0.000271442 | 1 | 0 | BeFree |
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