PLAU基因详情-基因数据库-基因云馆

PLAU(plasminogen activator, urokinase) 转至新版数据库

基因简称(symbol)

PLAU [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

URK|UPA

基因家族代码(gene_family_id)

[HGNC] [GenScript]

omim代码

191840

entrez码

5328 [Vega]

vega基因码

OTTHUMG00000018494

ensembl基因码

ENSG00000122861 [Ensembl]

基因家族(gene family)

refseq数据库代号

NM_002658

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

10q24

同源基因名称(alias name)

基因名称批准使用时间(date_approved_reserved)

2001-06-22T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

更新时间(date_modified)

2015-04-22T00:00:00Z

ucsc码

uc001jwa.3

ena

BC013575

ccds数据码

CCDS7339|CCDS44442

uniprot数据码

P00749

pubmed代码

2415429

mgd码

MGI:97611

rgd码

RGD:3343

生命科学数据库(lsdb)

更新时间(date modified)

2015-04-22T00:00:00Z

cosmic

PLAU

mirbase

基因曾用简称(prev symbol)

基因曾用名称(prev name)

homeodb

cosmic

PLAU

snornabase

bioparadigms slc

orphanet

223447

假基因信息(pseudogeneorg)

horde id

merops

S01.231

imgt

iuphar

objectId:2393

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

3.4.21.68

中间纤维数据库

10q24

This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

[中文简述(自动翻译):] 该基因编码参与细胞外基质的降解，并可能肿瘤细胞迁移和增殖的丝氨酸蛋白酶。在该基因的具体多态性可能与迟发型阿尔茨海默氏病相关联，并且还具有降低的亲和力的纤维蛋白结合。这种蛋白由纤维蛋白溶酶原的精氨酸 - 瓦尔债券的具体裂解转化纤溶酶原为纤溶酶。纤溶酶反过来切割该蛋白在一个赖氨酸 - 异亮氨酸键，以形成在其中单个二硫键的氨基末端A链连接到催化活性，羧基端B链的两链衍生物。该双链衍生物也称为HMW-uPA的（高分子量的uPA）。 HMW-uPA的可以由链A的切割进一步加工成LMW-uPA的（低分子量的uPA）成短链中的（A1）和氨基末端片段。 LMW-uPA的是蛋白水解活性的，但不绑定到特异受体。已发现该基因编码不同亚型选择性剪接转录变异体。 [由RefSeq的，2009年2月提供]

OMIM数据库中对PLAU基因的介绍 Wikipedia数据库中对PLAU基因的介绍

PLAU基因的碱基序列：[NCBI]

PLAU基因的碱基突变：显示全部snp

rs4065 rs1050120 rs1050122 rs1050124 rs1916340 rs1916341 rs2227552 rs2227553 rs2227554 rs2227555 rs2227556 rs2227557 rs2227558 rs2227560 rs2227561 rs2227562 rs2227563 rs2227564 rs2227565 rs2227566 rs2227567 rs2227568 rs2227569 rs2227570 rs2227571 rs2227572 rs2227573 rs2227574 rs2227579 rs2227580 rs2227581 rs2227582 rs2227583 rs3805118 rs4007230 rs11000806 rs12255769

rs55695810 rs55744193 rs56009862 rs56295603 rs59587909 rs61567551 rs61864535 rs67445792 rs72816318 rs72816319 rs72816325 rs75478288 rs76807842 rs78289523 rs112091894 rs112507550 rs112529227 rs112760283 rs112784885 rs113931971 rs114299227 rs114904384 rs115703038 rs117134857 rs117135013 rs117953441 rs118083423 rs138262122 rs138301843 rs138589166 rs139072795 rs139131357 rs139271997 rs140333999 rs140559980 rs141410181 rs141630912 rs141806757 rs142059320 rs142117323 rs142333203 rs142352538 rs143383352 rs143893486 rs143947102 rs144008112 rs144124124 rs145070893 rs145102078 rs145634997 rs145865648 rs146168437 rs146277280 rs146441819 rs146463052 rs146899371 rs147117027 rs147372618 rs147382460 rs147752136 rs148318390 rs148333167 rs148650588 rs148701277 rs148995703 rs149099771 rs149197795 rs149516796 rs149650503 rs149836022 rs149869183 rs150389556 rs150522269 rs150574792 rs181062146 rs181225602 rs181376776 rs182400061 rs183208966 rs183371156 rs184153523 rs184167945 rs185856064 rs185909762 rs186091908 rs186447765 rs186669250 rs186728610 rs187333809 rs188303497 rs188929828 rs189278700 rs189541006 rs190634377 rs190769030 rs190912758 rs191017354 rs191153987 rs192311262 rs192545728 rs192623012 rs199520267 rs199700503 rs200165551 rs200225644 rs200927138 rs201299522 rs201589894 rs201591610 rs201687228 rs201795845 rs201822924 rs201834187 rs201881239 rs201968257 rs367588535 rs367716060 rs367917192 rs367930651 rs368655748 rs368672601 rs368869045 rs368941751 rs368965192 rs369662596 rs369779851 rs370278611 rs370446684 rs370557565 rs371106595 rs371199984 rs371227106 rs371297216 rs371371222 rs371542108 rs371765951 rs372331139 rs372430384 rs372460458 rs372720180 rs372730940 rs373215033 rs373237459 rs373858934 rs373870847 rs374027239 rs374130621 rs374232402 rs374267816 rs374422519 rs374459067 rs375001283 rs375029894 rs375246282 rs375283622 rs375669901 rs375950656 rs376138058 rs376161294 rs376226376 rs376373742 rs376392651 rs376665535 rs376883758 rs377105108 rs377124818 rs377412161 rs398014134 rs527342724 rs527407052 rs527937347 rs528323261 rs528721328 rs528761202 rs529139340 rs529153637 rs530343972 rs530441175 rs530730869 rs530825556 rs531327494 rs531366496 rs531449884 rs532861475 rs533020384 rs533077465 rs533185248 rs534023443 rs534023550 rs534034767 rs535144178 rs535237670 rs535744023 rs536153829 rs536344619 rs537345429 rs537611866 rs537740819 rs538342269 rs538359879 rs538722826 rs539278940 rs540507727 rs542157536 rs542595564 rs542883509 rs543197904 rs543959601 rs544571649 rs544864676 rs545479834 rs545559536 rs546637178 rs546745404 rs546931331 rs547149070 rs547332065 rs548291948 rs548350282 rs549007112 rs549461157 rs549463604 rs549638430 rs549887547 rs550033766 rs550111301 rs550293900 rs550846533 rs551304555 rs552281163 rs552343722 rs553166353 rs553644377 rs553955010 rs554166865 rs554223970 rs554534634 rs554561296 rs556045420 rs556231880 rs556245855 rs556666631 rs556806437 rs557212899 rs557545378 rs557926110 rs558071180 rs558374255 rs558515797 rs558668565 rs558920700 rs559834339 rs559848125 rs560661806 rs560674195 rs561355605 rs561523119 rs562935956 rs563103946 rs563159701 rs563635073 rs563669529 rs563923793 rs565203384 rs565284834 rs565514556 rs565576288 rs566056557 rs566512515 rs567586364 rs568057544 rs568236500 rs568342316 rs568507000 rs568507451 rs569957633 rs569996769 rs570299329 rs570437714 rs570460716 rs570628652 rs570899214 rs571485837 rs571518049 rs572663178 rs572750016 rs573124485 rs574195820 rs574616627 rs574988636 rs575196444 rs576047514 rs576368029 rs576808058 rs577291297 rs745529389 rs745651664 rs745821284 rs745998178 rs746197822 rs746212195 rs746302225 rs746394197 rs746472439 rs746596167 rs746776336 rs746786385 rs747051640 rs747143309 rs747155451 rs747484365 rs747727351 rs747752586 rs747778238 rs747902275 rs747911170 rs747959312 rs748100957 rs748199905 rs748396564 rs748612292 rs748772626 rs748862531 rs748966578 rs749039069 rs749165945 rs749259807 rs749511125 rs749532718 rs749626562 rs749821755 rs749861164 rs750103383 rs750391337 rs750452037 rs750595191 rs750614609 rs750937039 rs750987729 rs751438925 rs751542437 rs751774005 rs751776753 rs751858306 rs751861644 rs751912254 rs751968486 rs752095700 rs752151133 rs752345173 rs752541456 rs752626889 rs752704197 rs752785511 rs752875420 rs753049435 rs753060051 rs753067235 rs753363345 rs753453645 rs753484289 rs753535848 rs753564952 rs753867816 rs753886853 rs753994566 rs754205897 rs754283224 rs754397889 rs754537952 rs754912158 rs754958267 rs755059369 rs755164208 rs755285429 rs755464577 rs755479753 rs755684568 rs755703533 rs755703595 rs755791500 rs755893348 rs755896059 rs756189472 rs756252604 rs756402191 rs756485791 rs756588363 rs756785379 rs756792457 rs756818784 rs757169446 rs757266930 rs757448093 rs757597152 rs757780690 rs757914576 rs758024818 rs758106450 rs758393377 rs758555754 rs758557616 rs758648701 rs758808565 rs758839583 rs758880290 rs759037884 rs759055099 rs759204395 rs759249841 rs759380746 rs759455005 rs759612977 rs759632843 rs759934592 rs759966729 rs760108497 rs760152676 rs760244673 rs760592972 rs760961705 rs760972301 rs760979977 rs761104867 rs761198672 rs761300954 rs761463492 rs761499143 rs761551446 rs761855045 rs761865856 rs762167389 rs762219387 rs762441547 rs762525019 rs762613177 rs762710927 rs762911780 rs763017439 rs763088001 rs763194825 rs763373135 rs763382972 rs763539417 rs763597131 rs763622420 rs763969436 rs764051398 rs764162545 rs764252595 rs764370249 rs764425558 rs764563021 rs764673067 rs764757639 rs764761357 rs764832112 rs765057401 rs765091817 rs765147277 rs765244714 rs765285707 rs765421749 rs765799266 rs765806971 rs766284806 rs766391157 rs766451751 rs766484416 rs766486323 rs766594093 rs766848068 rs767024253 rs767040788 rs767130422 rs767220548 rs767324226 rs767416770 rs767454749 rs767790362 rs767812805 rs767845639 rs767933395 rs767941674 rs767969176 rs767978842 rs767993253 rs768054670 rs768245891 rs768435349 rs768553821 rs768958360 rs769535733 rs769621432 rs769671802 rs769766918 rs769839032 rs769862196 rs769875362 rs770137681 rs770181188 rs770199271 rs770554037 rs770661625 rs770663585 rs770809780 rs770858054 rs771007926 rs771118510 rs771200321 rs771325395 rs771521643 rs771705787 rs771785034 rs771848360 rs771903964 rs771958773 rs772150449 rs772238457 rs772421529 rs772615182 rs772716620 rs772730235 rs772988818 rs773178013 rs773227513 rs773321824 rs773330520 rs773549475 rs773660601 rs773743548 rs773949170 rs773954892 rs774129403 rs774142287 rs774154847 rs774240822 rs774324202 rs774631447 rs774829526 rs774861031 rs774929635 rs774958481 rs775017488 rs775019547 rs775177834 rs775296618 rs775372285 rs775718740 rs775944641 rs776150636 rs776172889 rs776285224 rs776428822 rs776538239 rs776620539 rs776662131 rs776782634 rs776879689 rs777175475 rs777328491 rs777355641 rs777360771 rs777370331 rs777446241 rs777564108 rs777749292 rs778210707 rs778398901 rs778612720 rs778693912 rs778886856 rs779159794 rs779258185 rs779261663 rs779278566 rs779534915 rs779641569 rs779657054 rs779735620 rs780219863 rs780329696 rs780329846 rs780393493 rs780417655 rs780523904 rs780600442 rs780899804 rs780991834 rs781144342 rs781170354 rs781354430 rs781444492 rs781446239 rs781529480 rs781692015 rs781695245 rs781710375 rs781782139 rs2227551 rs2459449 rs3805118 rs11339212 rs11346650 rs55908890 rs58048583 rs61709229 rs74579986 rs75750371 rs76951221 rs77597235 rs80255548 rs111307659 rs112187025 rs114129421 rs114781878 rs116141658 rs139449696 rs139676048 rs140024926 rs140313409 rs142652669 rs144725011 rs145348571 rs146594608 rs147392966 rs149674944 rs151015329 rs181841088 rs183388310 rs183983574 rs185040137 rs186607308 rs187801503 rs188242188 rs189278700 rs190314999 rs191448168 rs191844535 rs201407499 rs370760281 rs528523847 rs533808064 rs533899290 rs535285228 rs535966133 rs538337156 rs540163738 rs540527592 rs543393403 rs548248917 rs549220613 rs550714250 rs550900602 rs551886623 rs554412372 rs554507455 rs556284364 rs558603809 rs560742219 rs561253350 rs561326811 rs563809696 rs565062152 rs566438752 rs567556558 rs567916290 rs569358438 rs569428770 rs571574309 rs577099769

PLAU基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

TCATCAAGTTCCATCGAACTG

59

GCACCAGTGAATGTTGGAG

59

GATACGAACAGGCGAACTG

59

ATTTCTTTGGGCAGTTGCA

59

TCAAGTTCCATCGAACTGTG

58

TTGCACCAGTGAATGTTGG

59

TCAAGTTCCATCGAACTGTG

58

TTGCACCAGTGAATGTTGG

59

TTACTGCAGGAACCCAGAC

59

CATGCACTCTTGGACAAGC

59

GTTGATGAAGACTTCACAGCTC

60

CTCTAAGACTGCCTCAGACC

59

ACTCCAAACGAACTGTGAC

58

ATTTCTTTGGGCAGTTGCA

59

GATACGAACAGGCGAACTG

59

TTTCTTTGGGCAGTTGCAC

60

AACATAATTACTGCAGGAACCC

58

CTTGGACAAGCAGCTTTAGG

59

TCATCAAGTTCCATCGAACTG

59

GCACCAGTGAATGTTGGAG

59

尚未收录相关数据

PLAU基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

PLAU基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0004252

E7ET40(UniProtKB)

IEA

GO:0005576

E7ET40(UniProtKB)

IEA

GO:0006508

E7ET40(UniProtKB)

IEA

GO:0001525

P00749(UniProtKB)

IEA

GO:0004252

P00749(UniProtKB)

IBA

GO:0004252

P00749(UniProtKB)

TAS

GO:0005515

P00749(UniProtKB)

IPI

GO:0005515

P00749(UniProtKB)

IPI

GO:0005515

P00749(UniProtKB)

IPI

GO:0005515

P00749(UniProtKB)

IPI

GO:0005576

P00749(UniProtKB)

TAS

GO:0005615

P00749(UniProtKB)

IDA

GO:0005886

P00749(UniProtKB)

TAS

GO:0005886

P00749(UniProtKB)

TAS

GO:0005886

P00749(UniProtKB)

TAS

GO:0005886

P00749(UniProtKB)

TAS

GO:0005886

P00749(UniProtKB)

TAS

GO:0005886

P00749(UniProtKB)

TAS

GO:0005925

P00749(UniProtKB)

IDA

GO:0006508

P00749(UniProtKB)

IEA

GO:0006935

P00749(UniProtKB)

TAS

GO:0007165

P00749(UniProtKB)

TAS

GO:0007283

P00749(UniProtKB)

IEA

GO:0007566

P00749(UniProtKB)

IEA

GO:0007596

P00749(UniProtKB)

IEA

GO:0008284

P00749(UniProtKB)

IEA

GO:0009986

P00749(UniProtKB)

IDA

GO:0010469

P00749(UniProtKB)

IDA

GO:0014823

P00749(UniProtKB)

IEA

GO:0014909

P00749(UniProtKB)

IEA

GO:0014910

P00749(UniProtKB)

IDA

GO:0014911

P00749(UniProtKB)

IEA

GO:0030335

P00749(UniProtKB)

IDA

GO:0033628

P00749(UniProtKB)

IDA

GO:0035729

P00749(UniProtKB)

IEA

GO:0042730

P00749(UniProtKB)

TAS

GO:0043403

P00749(UniProtKB)

IEA

GO:0055093

P00749(UniProtKB)

IEA

GO:0060279

P00749(UniProtKB)

IEA

GO:0061041

P00749(UniProtKB)

IC

GO:0070062

P00749(UniProtKB)

IDA

GO:0070062

P00749(UniProtKB)

IDA

GO:0070997

P00749(UniProtKB)

IEA

GO:0071222

P00749(UniProtKB)

IEA

GO:0071333

P00749(UniProtKB)

IEA

GO:0071456

P00749(UniProtKB)

IEA

GO:0071498

P00749(UniProtKB)

IEA

GO:0072734

P00749(UniProtKB)

IEA

GO:2000097

P00749(UniProtKB)

IDA

GO:2000345

P00749(UniProtKB)

IEA

GO:2000379

P00749(UniProtKB)

IEA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控PLAU基因的相关microRNA：

hsa-miR-192 hsa-miR-10b hsa-miR-10b* hsa-miR-193b hsa-miR-23b hsa-miR-215

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Alzheimer's Disease	0.225099593	6	0	CTD_human_GAD_LHGDN_MGD
Myocardial Infarction	0.202638474	8	0	BeFree_CTD_human_GAD_RGD
Reperfusion Injury	0.2	2	0	CTD_human_RGD
Thrombosis	0.2	7	0	CTD_human_RGD
Intracranial Hemorrhages	0.2	5	0	CTD_human_RGD
Asthenozoospermia	0.2	1	0	CTD_human_RGD
Brain Edema	0.2	2	0	CTD_human_RGD
Neoplasm Metastasis	0.150964236	97	0	BeFree_CTD_human_LHGDN
Prostatic Neoplasms	0.136346101	8	0	CTD_human_LHGDN
Asthma	0.128715934	5	0	BeFree_CTD_human_LHGDN
Adenocarcinoma	0.127620235	10	0	BeFree_CTD_human_LHGDN
Pancreatic Neoplasm	0.126263026	5	0	BeFree_CTD_human_LHGDN
Quebec platelet disorder	0.123452799	4	0	BeFree_GAD_ORPHANET
Carcinoma, Transitional Cell	0.122995792	2	0	BeFree_CTD_human_LHGDN
Idiopathic Pulmonary Fibrosis	0.122995792	1	0	BeFree_CTD_human_LHGDN
Stomach Neoplasms	0.12272435	2	0	CTD_human_LHGDN
Bone neoplasms	0.120271442	2	0	BeFree_CTD_human
Coronary heart disease	0.120271442	3	1	BeFree_CTD_human
Liver Cirrhosis	0.120271442	2	0	BeFree_CTD_human
Angina Pectoris	0.12	1	0	CTD_human
Angina, Unstable	0.12	1	0	CTD_human
Anuria	0.12	1	0	CTD_human
Arterial Occlusive Diseases	0.12	4	0	CTD_human
Carotid Artery Diseases	0.12	1	0	CTD_human
Intracranial Embolism and Thrombosis	0.12	1	0	CTD_human
Cerebral Infarction	0.12	3	0	CTD_human
Brain Ischemia	0.12	4	0	CTD_human
Cerebrovascular Disorders	0.12	2	0	CTD_human
IGA Glomerulonephritis	0.12	1	0	CTD_human
Graft Occlusion, Vascular	0.12	4	0	CTD_human
Heart Rupture, Post-Infarction	0.12	1	0	CTD_human
Hematuria	0.12	1	0	CTD_human
Hemorrhage	0.12	4	0	CTD_human
Hypotension	0.12	1	0	CTD_human
Inflammatory Bowel Diseases	0.12	1	1	GWASCAT
Ischemia	0.12	2	0	CTD_human
Neoplasm Invasiveness	0.12	2	0	CTD_human
Neoplasm Recurrence, Local	0.12	1	0	CTD_human
Nephritis	0.12	1	0	CTD_human
Pulmonary Embolism	0.12	6	0	CTD_human
Henoch-Schoenlein Purpura	0.12	2	0	CTD_human
Cerebrovascular accident	0.12	1	0	CTD_human
Thromboembolism	0.12	1	0	CTD_human
Venous Thrombosis	0.12	4	0	CTD_human
Ventricular Fibrillation	0.12	1	0	CTD_human
Cholesterol Embolism	0.12	1	0	CTD_human
Sagittal Sinus Thrombosis	0.12	1	0	CTD_human
Infarction, Middle Cerebral Artery	0.12	3	0	CTD_human
Cerebral Hemorrhage	0.12	5	0	CTD_human
Mammary Neoplasms	0.106147803	16	0	BeFree_LHGDN_RGD
Bladder Neoplasm	0.088173051	4	0	LHGDN_RGD
Chronic Obstructive Airway Disease	0.082995792	3	0	BeFree_LHGDN_RGD
Acute Lung Injury	0.08272435	3	0	LHGDN_RGD
Pulmonary Fibrosis	0.081085767	5	0	BeFree_RGD
Kidney Failure, Chronic	0.080271442	2	0	BeFree_RGD
Liver Cirrhosis, Experimental	0.080271442	3	0	BeFree_RGD
Transient Ischemic Attack	0.08	2	0	RGD
Diabetic Nephropathy	0.08	1	0	RGD
Cardiomegaly	0.08	1	0	RGD
Liver Cirrhosis, Alcoholic	0.08	1	0	RGD
Mammary Neoplasms, Experimental	0.08	1	0	RGD
Status Epilepticus	0.08	2	0	RGD
Sciatic Neuropathy	0.08	2	0	RGD
Strongylida Infections	0.08	1	0	RGD
Hyperoxia	0.08	1	0	RGD
Lung Injury	0.08	1	0	RGD
Hypoxia-Ischemia, Brain	0.08	2	0	RGD
Breast Carcinoma	0.013572094	50	0	BeFree
Malignant neoplasm of breast	0.013300652	49	0	BeFree
Colorectal Neoplasms	0.011440285	6	0	BeFree_LHGDN
Glioblastoma	0.010334654	20	0	BeFree_LHGDN
Colorectal Cancer	0.009815515	10	0	BeFree_GAD
Liver carcinoma	0.009520329	16	0	BeFree_LHGDN
Malignant neoplasm of prostate	0.009424521	27	0	BeFree_GAD
Squamous cell carcinoma	0.008977445	15	0	BeFree_LHGDN
Malignant neoplasm of ovary	0.008805692	17	0	BeFree_GAD
Endometriosis	0.008715934	4	0	BeFree_LHGDN
ovarian neoplasm	0.008715934	5	0	BeFree_LHGDN
Glioma	0.00842463	22	0	BeFree_LHGDN
Inflammation	0.008173051	3	0	LHGDN
Prostate carcinoma	0.006786047	25	0	BeFree
Malignant neoplasm of lung	0.006362715	8	0	BeFree_GAD
Meningioma	0.006263026	5	0	BeFree_LHGDN
Thyroid Neoplasm	0.005720142	3	0	BeFree_LHGDN
Rheumatoid Arthritis	0.005634266	3	0	BeFree_GAD_LHGDN
Colonic Neoplasms	0.0054487	2	0	LHGDN
Hyperplasia	0.0054487	2	0	LHGDN
Mitral Valve Prolapse Syndrome	0.005362824	1	0	BeFree_GAD_LHGDN
Tumor Progression	0.005157396	19	0	BeFree
melanoma	0.004353001	7	0	BeFree_LHGDN
Stomach Carcinoma	0.00434307	16	0	BeFree
Malignant neoplasm of stomach	0.004071628	15	0	BeFree
Ovarian Carcinoma	0.004071628	15	0	BeFree
Renal Cell Carcinoma	0.003810118	4	0	BeFree_LHGDN
Atherosclerosis	0.003538676	4	0	BeFree_LHGDN
Sarcoma	0.003538676	3	0	BeFree_LHGDN
Colon Carcinoma	0.003257302	12	0	BeFree
Cardiovascular Diseases	0.002995792	2	0	BeFree_LHGDN
Pneumonia	0.002995792	2	0	BeFree_LHGDN
Malignant tumor of colon	0.002985861	11	0	BeFree
Colorectal Carcinoma	0.002985861	11	0	BeFree
Malignant neoplasm of mouth	0.002909916	3	0	BeFree_GAD
Chordoma	0.00272435	1	0	LHGDN
Cystic Fibrosis	0.00272435	1	0	LHGDN
Dermatitis	0.00272435	1	0	LHGDN
Dermatitis, Atopic	0.00272435	1	0	LHGDN
Esophageal Neoplasms	0.00272435	1	0	LHGDN
Hemoglobinuria, Paroxysmal	0.00272435	1	0	LHGDN
Lung Neoplasms	0.00272435	1	0	LHGDN
Mouth Neoplasms	0.00272435	1	0	LHGDN
Degenerative polyarthritis	0.00272435	1	0	LHGDN
Periodontal Diseases	0.00272435	1	0	LHGDN
Prostatic Intraepithelial Neoplasias	0.00272435	1	0	LHGDN
Osteoarthritis, Knee	0.00272435	1	0	LHGDN
Infection	0.00272435	1	0	LHGDN
Diabetes Mellitus, Insulin-Dependent	0.002638474	1	0	BeFree_GAD
Chorioamnionitis	0.002367032	1	0	GAD
Fetal Membranes, Premature Rupture	0.002367032	1	0	GAD
Premature Obstetric Labor	0.002367032	1	0	GAD
Multiple Sclerosis	0.002367032	1	0	GAD
Osteoporosis	0.002367032	1	0	GAD
Pneumoconiosis	0.002367032	1	0	GAD
Polycystic Ovary Syndrome	0.002367032	1	0	GAD
Pre-Eclampsia	0.002367032	1	0	GAD
Respiratory Distress Syndrome, Adult	0.002367032	1	0	GAD
Premature Birth	0.002367032	1	0	GAD
Nephrolithiasis	0.002367032	1	0	GAD
Urolithiasis	0.002367032	1	0	GAD
Hepatopulmonary Syndrome	0.002367032	1	0	GAD
Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified	0.002367032	1	0	GAD
Severe Combined Immunodeficiency	0.002171535	8	0	BeFree
Secondary malignant neoplasm of lymph node	0.002171535	8	0	BeFree
Immunologic Deficiency Syndromes	0.001628651	6	0	BeFree
Pancreatic carcinoma	0.001628651	6	0	BeFree
Malignant neoplasm of pancreas	0.001628651	6	0	BeFree
Carcinoma of lung	0.001628651	6	0	BeFree
Non-Small Cell Lung Carcinoma	0.001357209	5	0	BeFree
Blood Coagulation Disorders	0.001085767	4	0	BeFree
Brain Neoplasms	0.001085767	4	0	BeFree
Hepatitis B	0.001085767	4	0	BeFree
Anaplastic astrocytoma	0.001085767	4	0	BeFree
Arteriosclerosis	0.000814326	3	0	BeFree
Noninfiltrating Intraductal Carcinoma	0.000814326	3	0	BeFree
Fibrosarcoma	0.000814326	3	0	BeFree
Secondary malignant neoplasm of lung	0.000814326	3	0	BeFree
Carcinoma breast stage IV	0.000814326	3	0	BeFree
Solid tumour	0.000814326	3	0	BeFree
Endometrial Carcinoma	0.000814326	3	0	BeFree
Secondary malignant neoplasm of liver	0.000814326	3	0	BeFree
Carcinogenesis	0.000814326	3	0	BeFree
Invasive breast carcinoma	0.000814326	3	0	BeFree
Tumor Angiogenesis	0.000814326	3	0	BeFree
Adenoma	0.000542884	2	0	BeFree
Aortic Aneurysm	0.000542884	2	0	BeFree
Astrocytoma	0.000542884	2	0	BeFree
Malignant neoplasm of urinary bladder	0.000542884	2	0	BeFree
Malignant neoplasm of endometrium	0.000542884	2	0	BeFree
Chondrosarcoma	0.000542884	2	0	BeFree
Hepatitis C	0.000542884	2	0	BeFree
HIV Infections	0.000542884	2	0	BeFree
Medulloblastoma	0.000542884	2	0	BeFree
Muscular Dystrophy	0.000542884	2	0	BeFree
Osteosarcoma	0.000542884	2	0	BeFree
Pterygium	0.000542884	2	0	BeFree
Kidney Failure	0.000542884	2	0	BeFree
Systemic Scleroderma	0.000542884	2	0	BeFree
Liver Failure	0.000542884	2	0	BeFree
Liver and Intrahepatic Biliary Tract Carcinoma	0.000542884	2	0	BeFree
Adenocarcinoma of pancreas	0.000542884	2	0	BeFree
Cervix carcinoma	0.000542884	2	0	BeFree
Malignant neoplasm of liver	0.000542884	2	0	BeFree
Disseminated Malignant Neoplasm	0.000542884	2	0	BeFree
Secondary malignant neoplasm of pancreas	0.000542884	2	0	BeFree
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site	0.000542884	2	0	BeFree
Alzheimer Disease, Late Onset	0.000542884	2	0	BeFree
Osteosarcoma of bone	0.000542884	2	0	BeFree
Carcinoma of bladder	0.000542884	2	0	BeFree
Malignant Pleural Mesothelioma	0.000542884	2	0	BeFree
Invasive Carcinoma	0.000542884	2	0	BeFree
Pancreatic Ductal Adenocarcinoma	0.000542884	2	0	BeFree
Breast Cancer Model	0.000542884	2	0	BeFree
Meningioma, benign, no ICD-O subtype	0.000542884	2	0	BeFree
Uterine Corpus Cancer	0.000542884	2	0	BeFree
Aneurysm	0.000271442	1	0	BeFree
Biliary Atresia	0.000271442	1	0	BeFree
Coronary Arteriosclerosis	0.000271442	1	1	BeFree
Adenoid Cystic Carcinoma	0.000271442	1	0	BeFree
Cystadenoma, Mucinous	0.000271442	1	0	BeFree
Dermatitis Herpetiformis	0.000271442	1	0	BeFree
Scleroderma	0.000271442	1	0	BeFree
Von Hippel-Lindau Syndrome	0.000271442	1	0	BeFree
Keratoconjunctivitis, Vernal	0.000271442	1	0	BeFree
Leg Ulcer	0.000271442	1	0	BeFree
Leukemia, Lymphocytic, Acute, L1	0.000271442	1	0	BeFree
Leukemia, Myelocytic, Acute	0.000271442	1	0	BeFree
Myeloid Leukemia	0.000271442	1	0	BeFree
Acute myelomonocytic leukemia	0.000271442	1	0	BeFree
Liver neoplasms	0.000271442	1	0	BeFree
Lymphatic Metastasis	0.000271442	1	0	BeFree
Meleda Disease	0.000271442	1	0	BeFree
Bullous pemphigoid	0.000271442	1	0	BeFree
Precancerous Conditions	0.000271442	1	0	BeFree
Proctitis	0.000271442	1	0	BeFree
Respiratory Tract Infections	0.000271442	1	0	BeFree
Rhabdomyosarcoma	0.000271442	1	0	BeFree
Seminoma	0.000271442	1	0	BeFree
Gastric ulcer	0.000271442	1	0	BeFree
Synovitis	0.000271442	1	0	BeFree
Pleural Effusion, Malignant	0.000271442	1	0	BeFree
Bone pain	0.000271442	1	0	BeFree
Arterial thrombosis	0.000271442	1	0	BeFree
Malignant neoplasm of brain	0.000271442	1	0	BeFree
Acute myocardial infarction	0.000271442	1	0	BeFree
Cicatrix, Hypertrophic	0.000271442	1	0	BeFree
Embryonal Carcinoma	0.000271442	1	0	BeFree
Carcinoma, Neuroendocrine	0.000271442	1	0	BeFree
Cholangiocarcinoma	0.000271442	1	0	BeFree
gliosarcoma	0.000271442	1	0	BeFree
Effects of heat	0.000271442	1	0	BeFree
Paroxysmal atrial fibrillation	0.000271442	1	0	BeFree
Anaplastic thyroid carcinoma	0.000271442	1	0	BeFree
Fibrosis, Liver	0.000271442	1	0	BeFree
Malignant Meningioma	0.000271442	1	0	BeFree
Carcinoma of ampulla of Vater	0.000271442	1	0	BeFree
Renal glomerular disease	0.000271442	1	0	BeFree
Stage IV Ovarian Carcinoma	0.000271442	1	0	BeFree
Metastatic melanoma	0.000271442	1	0	BeFree
Cancer of Head and Neck	0.000271442	1	0	BeFree
Squamous cell carcinoma of esophagus	0.000271442	1	0	BeFree
Adenocarcinoma of colon	0.000271442	1	0	BeFree
Pulmonary lymphangioleiomyomatosis	0.000271442	1	0	BeFree
Erythrokeratoderma	0.000271442	1	0	BeFree
Malignant Glioma	0.000271442	1	0	BeFree
Squamous cell carcinoma of mouth	0.000271442	1	0	BeFree
Epithelial ovarian cancer	0.000271442	1	0	BeFree
Primary malignant neoplasm of brain	0.000271442	1	0	BeFree
Thrombocytosis	0.000271442	1	0	BeFree
Advanced cancer	0.000271442	1	0	BeFree
Intraepithelial Neoplasia	0.000271442	1	0	BeFree
Stromal Neoplasm	0.000271442	1	0	BeFree
Ischemic stroke	0.000271442	1	0	BeFree
Invasive Ductal Breast Carcinoma	0.000271442	1	0	BeFree
Rhinorrhea	0.000271442	1	0	BeFree
Precursor B-cell lymphoblastic leukemia	0.000271442	1	0	BeFree
Adenoma of large intestine	0.000271442	1	0	BeFree
Pleural Mesothelioma	0.000271442	1	0	BeFree
Renal carcinoma	0.000271442	1	0	BeFree
Cardiac fibrosis	0.000271442	1	0	BeFree
Hepatocarcinogenesis	0.000271442	1	0	BeFree
Glioblastoma Multiforme	0.000271442	1	0	BeFree
tumor vasculature	0.000271442	1	0	BeFree
Laryngeal cleft	0.000271442	1	0	BeFree
Coronary Artery Disease	0.000271442	1	1	BeFree
Limb ischemia	0.000271442	1	0	BeFree
Intracranial glioma	0.000271442	1	0	BeFree