PISD(phosphatidylserine decarboxylase) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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22q12.2
基因染色体位置图

Phosphatidylserine decarboxylases (PSDs; EC 4.1.1.65) catalyze the formation of phosphatidylethanolamine (PE) by decarboxylation of phosphatidylserine (PS). Type I PSDs, such as PISD, are targeted to the inner mitochondrial membrane by an N-terminal targeting sequence. PISD also contains a conserved LGST motif that functions as an autocatalytic cleavage site where the proenzyme is split into mature alpha and beta subunits (Schuiki and Daum, 2009 [PubMed 19165886]).[supplied by OMIM, Jul 2010]

[中文简述(自动翻译):]  磷脂酰丝氨酸脱羧酶(月台幕门; EC 4.1.1.65)催化磷脂酰乙醇胺(PE)的磷脂所(PS)的脱羧形成。 I型的PSD,如PISD,定位到由N-末端定位序列线粒体内膜。 PISD还包含一个保守LGST基序,其功能如同一个自催化切割位点,其中酶原被分成成熟的α和β亚基(Schuiki和Daum的,2009年[搜索PubMed 19165886])。[由OMIM,2010年7月供给]

PISD基因的碱基序列:[NCBI]
PISD基因的碱基突变:           显示全部snp
rs5998059       rs9619213       rs9621298       rs61249659       rs78201558       rs78552981       rs111365387       rs111786837       rs114835722       rs115497585       rs116546080       rs137923833       rs138088148       rs139533545       rs139709758       rs139802809       rs140518382       rs140635844       rs142945357       rs143378500       rs143706226       rs143716966       rs144176887       rs144842700       rs145139121       rs146188283       rs146805605       rs147210747       rs147371584       rs148207532       rs148585801       rs150663615       rs150768643       rs181525223       rs182886052       rs186643998       rs189696412      
rs199559479       rs199743543       rs199747774       rs200000861       rs200180449       rs200250955       rs200442774       rs200770866       rs200830751       rs201027944       rs201154270       rs201310686       rs201610748       rs201966039       rs202137922       rs368409664       rs369803974       rs370290852       rs370526379       rs372082408       rs372114692       rs372611579       rs373653948       rs374309837       rs374628802       rs374736938       rs375010053       rs376116795       rs376140173       rs376175941       rs527520820       rs527599233       rs528514257       rs529945588       rs530174748       rs531463079       rs532663506       rs534289437       rs534998979       rs535331006       rs536629982       rs537280387       rs537629799       rs538726930       rs539072249       rs540962531       rs545264794       rs545717569       rs546320192       rs547244208       rs547853789       rs548455931       rs548852007       rs551115207       rs551301563       rs552559658       rs554824986       rs554938934       rs555866970       rs557148265       rs559486576       rs562135416       rs563477439       rs563741547       rs565066020       rs567617597       rs568290948       rs568379273       rs568761820       rs570046089       rs571033035       rs571363852       rs571415161       rs572600039       rs574802910       rs575615631       rs575703790       rs576778673       rs745472048       rs745523796       rs746053435       rs746558458       rs746888629       rs746935386       rs747033677       rs747266627       rs747567795       rs748015775       rs748151520       rs748372650       rs748626335       rs749149597       rs749241240       rs749448875       rs749735784       rs749989572       rs750037214       rs750260566       rs750329462       rs751137396       rs751526824       rs752128107       rs752370590       rs752381061       rs752423696       rs752960067       rs753228533       rs753332282       rs753582530       rs754079183       rs754138317       rs754399145       rs754561240       rs754866362       rs755072359       rs755413379       rs755645025       rs755909957       rs756201810       rs756811513       rs757272795       rs758087409       rs758199007       rs758206483       rs758867171       rs758927458       rs759396349       rs759665981       rs759761758       rs759855426       rs760199435       rs760619419       rs760875261       rs761449484       rs761636680       rs762395199       rs762535882       rs762590482       rs762934328       rs763094454       rs763188379       rs763673248       rs763902762       rs763928781       rs764413071       rs764644242       rs764822389       rs764873699       rs765049480       rs765165531       rs765439843       rs765500864       rs765814088       rs766274865       rs766541600       rs766600626       rs766603764       rs767254535       rs767517572       rs767532363       rs767962629       rs768564054       rs768652071       rs768687189       rs768977700       rs769038694       rs769378097       rs769442605       rs769652284       rs769789016       rs769890475       rs770424911       rs770513175       rs770601345       rs771117173       rs771417980       rs771449559       rs771507888       rs771884397       rs772225841       rs772344640       rs772922864       rs773294304       rs773637852       rs774413824       rs774511607       rs774604673       rs775076175       rs775278401       rs775601179       rs776306898       rs776428951       rs776448111       rs776684573       rs776788536       rs776844636       rs777361129       rs777786765       rs777835869       rs778161259       rs778194666       rs778296670       rs778522674       rs778922536       rs779032144       rs779538509       rs779612736       rs779953809       rs780487520       rs780638573       rs780646232       rs780689748       rs781082825       rs781651571       rs781775700       rs8461       rs9287       rs9956       rs14034       rs15086       rs16682       rs738685       rs760908       rs761746       rs910549       rs1043954       rs1044085       rs2009893       rs2273262       rs2273263       rs3747156       rs3747157       rs4602315       rs4820987       rs4989480       rs5753732       rs5753733       rs5753734       rs5753738       rs5753741       rs5994416       rs5994417       rs5998062       rs5998063       rs5998064       rs5998065       rs5998066       rs5998067       rs5998068       rs5998069       rs5998070       rs5998071       rs5998072       rs5998074       rs7287937       rs7288742       rs7291941       rs7364312       rs8135502       rs8139316       rs8139890       rs8141236       rs9306267       rs9306268       rs9609341       rs9619214       rs9619215       rs9619216       rs9619217       rs9619218       rs9619221       rs9621297       rs9621299       rs9621300       rs9621301       rs9621302       rs9621304       rs9621305       rs9621306       rs9621307       rs9621308       rs9621310       rs10154390       rs10596164       rs11556539       rs11556540       rs11703079       rs11703102       rs11703787       rs11703798       rs11703808       rs11705156       rs11705292       rs11912189       rs11912794       rs12158002       rs12160788       rs12162806       rs12165609       rs12167027       rs12167269       rs12167999       rs12168918       rs12171217       rs12627933       rs16985114       rs16985133       rs16989329       rs16989334       rs16989336       rs16989337       rs16989347       rs16989356       rs16989374       rs16989378       rs16989379       rs17833937       rs28374120       rs28760352       rs34103525       rs34298713       rs34399834       rs34561628       rs34736247       rs35341171       rs41282571       rs41302569       rs55648708       rs55673702       rs55735011       rs55779244       rs55844032       rs55868468       rs55916646       rs55931230       rs55946723       rs55989741       rs56112397       rs56143643       rs56156742       rs56211407       rs56219558       rs56227594       rs56298010       rs56305493       rs56318295       rs56337539       rs56406828       rs56662300       rs57103115       rs57725422       rs57907329       rs57955202       rs58926861       rs59319463       rs60359561       rs60526650       rs60746452       rs60783010       rs61151238       rs61747365       rs62237834       rs62237836       rs62237837       rs62237838       rs62237839       rs62237841       rs62237843       rs62237844       rs62237845       rs62237846       rs62237847       rs62237848       rs62237849       rs62237850       rs62237852       rs62237855       rs62237857       rs62239167       rs62239168       rs62239169       rs62239170       rs62239172       rs62239173       rs62239174       rs66666267       rs67935422       rs71184515       rs71184516       rs71320905       rs71331299       rs71772171       rs72370751       rs73160689       rs73160696       rs73160697       rs73160700       rs73162104       rs73162106       rs73162112       rs73400284       rs73400287       rs73402152       rs73402160       rs73402163       rs73402167       rs73402170       rs73881394       rs73881395       rs73881396       rs73881398       rs73881400       rs74655478       rs74710327       rs75317622       rs75712797       rs75939412       rs76005862       rs76040166       rs76168705       rs76352720       rs76444215       rs76456031       rs76483730       rs76543745       rs76684125       rs76742988       rs76816574       rs77181208       rs77412371       rs77438998       rs77442287       rs77564448       rs77737188       rs78248063       rs78316027       rs78531612       rs78605342       rs78827638       rs78987708       rs79003718       rs79084989       rs79540540       rs79593072       rs79617263       rs79687287       rs79788237       rs79948604       rs80302968       rs111260596       rs111303474       rs111322761       rs111328511       rs111347656       rs111353864       rs111457236       rs111510811       rs111537600       rs111552117       rs111584003       rs111658926       rs111689818       rs111697884       rs111811754       rs111885365       rs111927246       rs111934124       rs111955043       rs112019579       rs112124795       rs112130465       rs112150157       rs112159216       rs112202482       rs112236469       rs112309594       rs112397785       rs112421502       rs112473938       rs112482256       rs112546751       rs112584421       rs112588915       rs112595939       rs112609252       rs112628523       rs112637715       rs112673900       rs112709944       rs112783086       rs112814832       rs112846381       rs112864888       rs112877920       rs112930031       rs112954137       rs113001421       rs113037024       rs113038274       rs113127193       rs113341672       rs113396217       rs113432798       rs113468712       rs113476860       rs113527717       rs113585076       rs113604273       rs113611012       rs113612277       rs113702068       rs113703448       rs113736805       rs113763150       rs113797189       rs113834145       rs113922453       rs113992242       rs114111509       rs114170547       rs114419013       rs114449294       rs114580454       rs114639710       rs114741311       rs114856294       rs114886964       rs114962330       rs115080618       rs115154670       rs115270917       rs115407295       rs115544747       rs115710630       rs115735326       rs115767908       rs115800295       rs115836166       rs115942202       rs116272739       rs116405397       rs116520767       rs116709791       rs116915633       rs116920551       rs116971071       rs117296997       rs117343380       rs117471565       rs117711962       rs137875167       rs137955558       rs137966413       rs138062139       rs138094567       rs138164860       rs138197572       rs138263079       rs138334987       rs138347447       rs138348841       rs138552593       rs138616215       rs138739243       rs138766332       rs138962064       rs139025695       rs139088204       rs139188977       rs139272727       rs139576940       rs139584294       rs139719676       rs139837437       rs139851887       rs139862235       rs140079491       rs140182005       rs140393171       rs140417354       rs140479024       rs140499111       rs140538746       rs140715774       rs140722465       rs140747496       rs140893263       rs141043691       rs141044708       rs141099128       rs141299772       rs141333524       rs141501344       rs141548250       rs141563467       rs141622088       rs141927025       rs142012365       rs142062770       rs142338374       rs142356234       rs142373474       rs142376089       rs142428847       rs142481217       rs142673322       rs142725754       rs142790252       rs142815539       rs142834656       rs142886672       rs143096536       rs143321925       rs143323643       rs143668627       rs143758294       rs143770927       rs143774685       rs144048513       rs144154825       rs144351347       rs144439854       rs144553808       rs144568821       rs144604725       rs144624624       rs144643824       rs144785400       rs144790103       rs144911389       rs144988662       rs145122088       rs145134788       rs145181625       rs145200600       rs145247337       rs145322644       rs145379662       rs145498046       rs145702359       rs145714160       rs145910827       rs145938004       rs146121782       rs146203138       rs146237094       rs146298997       rs146302304       rs146601673       rs146609340       rs146627665       rs146739243       rs146746700       rs146840606       rs146860075       rs146860114       rs146864296       rs146960059       rs147194092       rs147404981       rs147670023       rs147677846       rs147874911       rs147996858       rs148064581       rs148132314       rs148153540       rs148252495       rs148311696       rs148531176       rs148680467       rs148689457       rs148741700       rs148851294       rs148920285       rs148971555       rs149008660       rs149053178       rs149109296       rs149215441       rs149269917       rs149448432       rs149449715       rs149634136       rs149794516       rs149844315       rs149846910       rs149916744       rs150139304       rs150198170       rs150235206       rs150295062       rs150355846       rs150444406       rs150507882       rs150561378       rs150614515       rs150823260       rs150881103       rs150994240       rs151003014       rs151056328       rs151136721       rs151266390       rs180744149       rs180781249       rs180816216       rs180865237       rs180879076       rs181359150       rs181451718       rs181518301       rs181528227       rs181576766       rs181630076       rs181656441       rs181747099       rs181770966       rs181934144       rs182077357       rs182303099       rs182305208       rs182313716       rs182441036       rs182554207       rs182672659       rs182754413       rs182762717       rs182803734       rs182813176       rs182853003       rs183149548       rs183233363       rs183301286       rs183316525       rs183398218       rs183400902       rs183406976       rs183412692       rs183547364       rs183652917       rs183947181       rs183960589       rs184027489       rs184089718       rs184099760       rs184102885       rs184139706       rs184170655       rs184203469       rs184736045       rs184864831       rs184879702       rs184880609       rs184903270       rs184984474       rs184999348       rs185016077       rs185094808       rs185522411       rs185624182       rs185642357       rs185669223       rs185688766       rs185772112       rs185900470       rs186131176       rs186278706       rs186302423       rs186329894       rs186392363       rs186417251       rs186486836       rs186576075       rs186950160       rs187075448       rs187126874       rs187227805       rs187295017       rs187336371       rs187497778       rs187518168       rs187527449       rs187562439       rs187658298       rs187690907       rs187716161       rs187893706       rs187908610       rs187922423       rs188006434       rs188283190       rs188299114       rs188300622       rs188311112       rs188323689       rs188418538       rs188422654       rs188549376       rs188561298       rs188576959       rs188675456       rs188835733       rs188946044       rs189104146       rs189187637       rs189197622       rs189206001       rs189342694       rs189343115       rs189353768       rs189445021       rs189505804       rs189614702       rs189708297       rs189723279       rs189828153       rs189836038       rs189855520       rs189978723       rs190059039       rs190074801       rs190148532       rs190248483       rs190383136       rs190388925       rs190486656       rs190582464       rs190620381       rs190721756       rs190736203       rs190754002       rs190889206       rs190986802       rs191029815       rs191124509       rs191355996       rs191360827       rs191373271       rs191507406       rs191511458       rs191537502       rs191693309       rs191864055       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rs577013889       rs577021497       rs577029537       rs577049180       rs577097646       rs577116513       rs577246016       rs577252156       rs577339830       rs577463398       rs577507120       rs577625993       rs577732740       rs577864310       rs577865135       rs577927774       rs577997510       rs578033946       rs578049484       rs578174841       rs578197642       rs745566257       rs745754639       rs745773412       rs745807486       rs745809672       rs745901218       rs746029338       rs746107012       rs746144142       rs746162293       rs746178128       rs746409824       rs746616946       rs746672347       rs746681292       rs746848491       rs746891486       rs746981083       rs746989199       rs747035473       rs747177542       rs747325568       rs747394036       rs747470390       rs747525388       rs747547427       rs747680892       rs747809556       rs747860528       rs747896901       rs748097491       rs748282653       rs748613360       rs748628755       rs748685896       rs748734308       rs748755482       rs748786359       rs748813948       rs749185587       rs749241259       rs749437346       rs749468799       rs749786832       rs749834707       rs750116304       rs750207364       rs750648956       rs750875431       rs750889368       rs750940336       rs751223803       rs751323332       rs751538096       rs751787309       rs751799680       rs751842641       rs751854215       rs751856642       rs752031125       rs752110353       rs752315628       rs752608085       rs752618029       rs752667686       rs752779598       rs753041772       rs753171358       rs753421419       rs753576057       rs753742426       rs753772634       rs753825292       rs753906406       rs753982996       rs754061675       rs754108769       rs754318936       rs754491430       rs754612768       rs754797089       rs754812426       rs755019199       rs755072493       rs755574124       rs755746962       rs756055665       rs756133021       rs756174844       rs756338100       rs756516965       rs756758439       rs756778732       rs756817655       rs756928955       rs757061708       rs757089939       rs757121535       rs757144975       rs757145483       rs757349016       rs757367185       rs757370252       rs757560616       rs757726502       rs757887180       rs757912380       rs758083555       rs758252783       rs758310178       rs758469811       rs758491348       rs758522926       rs758846093       rs759159203       rs759165897       rs759191818       rs759386275       rs759469362       rs759601970       rs759759858       rs759764933       rs759936162       rs760098773       rs760252426       rs760280251       rs760292653       rs760346623       rs760491476       rs760673286       rs760921484       rs761074764       rs761093606       rs761245101       rs761331516       rs761473387       rs761669619       rs761942222       rs762042275       rs762096883       rs762103910       rs762220195       rs762291142       rs762443044       rs762588576       rs762780859       rs762898686       rs763007888       rs763072726       rs763242089       rs763333149       rs763543767       rs763981773       rs764054898       rs764237818       rs764242570       rs764265582       rs764290821       rs764411173       rs764568820       rs764569997       rs764947484       rs765027910       rs765032652       rs765077485       rs765260314       rs765343690       rs765378301       rs765430817       rs765563551       rs765802509       rs765804038       rs766134071       rs766135986       rs766323514       rs766365481       rs766679045       rs766742662       rs766769743       rs766772550       rs767091362       rs767100525       rs767277589       rs767570444       rs767573852       rs767652231       rs767669737       rs767933433       rs768025970       rs768069104       rs768123953       rs768188873       rs768243917       rs768256889       rs768276835       rs768439505       rs768749210       rs768929296       rs769049180       rs769217822       rs769287992       rs769378162       rs769410256       rs769463566       rs769499376       rs769540903       rs769868416       rs769990904       rs770179649       rs770277250       rs770330701       rs770359288       rs770479396       rs770524072       rs770734329       rs770786006       rs771154614       rs771350760       rs771582771       rs771586554       rs771678477       rs771741786       rs771932725       rs771982258       rs772097466       rs772137869       rs772221736       rs772533346       rs772613650       rs772743341       rs772901333       rs772989439       rs773352927       rs773404778       rs773407493       rs773465161       rs773597917       rs773668209       rs774021378       rs774071660       rs774074651       rs774253145       rs774446096       rs774467193       rs774484568       rs774500671       rs774777135       rs774799962       rs774887168       rs775109135       rs775159475       rs775307712       rs775314748       rs775561013       rs775574915       rs775666214       rs775673517       rs775769922       rs775834044       rs775947416       rs776000864       rs776426221       rs776707469       rs776717426       rs776743029       rs776839681       rs776906445       rs777153659       rs777282648       rs777314902       rs777322299       rs777348795       rs777410422       rs777669105       rs778044678       rs778097770       rs778243309       rs778311383       rs778467604       rs778499710       rs778518821       rs778757474       rs778860398       rs778869821       rs778975691       rs779100538       rs779267705       rs779352619       rs779541727       rs779557749       rs779746980       rs779798286       rs779973104       rs780185289       rs780386723       rs780523741       rs780709289       rs780766629       rs780869246       rs781057071       rs781069349       rs781098843       rs781123205       rs781170510       rs781173026       rs781254076      

PISD基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ATATGGAGGCACTGACACC
59
GAATAGAGGGTCAGGGCTG
59
TCCTCTACTACCTCCTGCC
59
CTTGTACAAAGCCACCCTG
58
TTTCATCTTTCCTGTGGTGGA
59
ATAGAGGGTCAGGGCTCTC
59
GAGGCAGAACAGTGATAAAGAC
59
GAATAGAGGGTCAGGGCTG
59
TCATCTTTCCTGTGGTGGA
58
GAATAGAGGGTCAGGGCTC
59
TGATGTGTCAGTCAGAGGC
59
GGGAAGTGCAACCATTTCG
59
GAGGACCTGCATCACTACC
59
ATCCGATGGGCTAATCACG
59
ATCACTACCGCAACCTCAG
59
ATCCGATGGGCTAATCACG
59
TGATATGGAGGCACTGACAC
59
GAATAGAGGGTCAGGGCTG
59
CTACTTTGACCGGGACCTG
59
CTGGAAATTGAAGTCCTTGGG
59
      尚未收录相关数据

PISD基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

PISD基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0004609
B1AKM6(UniProtKB)
IEA
GO:0008654
B1AKM6(UniProtKB)
IEA
GO:0004609
B1AKM8(UniProtKB)
IEA
GO:0008654
B1AKM8(UniProtKB)
IEA
GO:0004609
H0Y7P7(UniProtKB)
IEA
GO:0008654
H0Y7P7(UniProtKB)
IEA
GO:0004609
Q9UG56(UniProtKB)
IEA
GO:0005634
Q9UG56(UniProtKB)
IDA
GO:0005743
Q9UG56(UniProtKB)
IEA
GO:0008654
Q9UG56(UniProtKB)
IEA
GO:0016021
Q9UG56(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控PISD基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Acquired Immunodeficiency Syndrome 0.002367032 1 0 GAD
Schizophrenia 0.001085767 4 0 BeFree
Mental disorders 0.000542884 2 0 BeFree
Malignant neoplasm of stomach 0.000542884 2 0 BeFree
Stomach Carcinoma 0.000542884 2 0 BeFree
Autistic Disorder 0.000271442 1 0 BeFree
Ulcerative Colitis 0.000271442 1 0 BeFree
Atrial Septal Defects 0.000271442 1 0 BeFree
Unipolar Depression 0.000271442 1 0 BeFree
Speech Delay 0.000271442 1 0 BeFree
Protein S Deficiency 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Major Depressive Disorder 0.000271442 1 0 BeFree
Autism Spectrum Disorders 0.000271442 1 0 BeFree
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