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The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  由该基因编码的蛋白质磷酸化维生素B6,对于维生素B6以吡哆醛-5-磷酸,在中间代谢的重要辅因子的转换所需的步骤。所编码的蛋白质是细胞质和可能作为同二聚体。可变剪接转录物变体已有描述,但它们的生物有效性尚未确定。 [由RefSeq的,2008年7月提供]
PDXK基因(以及对应的蛋白质)的细胞分布位置:
PDXK基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Status Epilepticus | 0.12 | 1 | 0 | CTD_human |
Liver Cirrhosis, Experimental | 0.08 | 1 | 0 | RGD |
Down Syndrome | 0.002995792 | 1 | 0 | BeFree_LHGDN |
Parkinson Disease | 0.002367032 | 1 | 0 | GAD |
Non-Small Cell Lung Carcinoma | 0.001085767 | 4 | 0 | BeFree |
Congenital chromosomal disease | 0.000271442 | 1 | 0 | BeFree |
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