The protocadherin beta cluster is one of three related gene clusters tandemly linked on chromosome five. The protocadherin genes have an immunoglobulin-like genomic organization, suggesting that a novel mechanism may be involved in their regulation and expression. The beta cluster contains 16 genes and 3 pseudogenes. Each gene product contains 6 extracellular cadherin domains and a cytoplasmic tail that diverges from other cadherin superfamily members. Unlike the alpha and gamma clusters, the beta cluster has a variable region but lacks a constant region. Without this downstream region of shared exons, each transcript encodes a unique cytoplasmic tail. The specific functions of these one-exon gene products are unknown; however, they are thought to play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  的protocadherin测试集群的五个染色体串联连接三个相关的基因簇之一。所述protocadherin基因都具有免疫球蛋白样基因组组织，这表明了一种新的机构可以在他们的调节和表达的参与。公测簇包含16个基因和3个假。每个基因产物中含有6外钙粘蛋白域和从其他钙粘蛋白超家族成员的分叉胞质尾。不同的是α和γ集群，公测集群具有可变区，但缺少恒定区。如果没有共同的外显子的这个下游区，每个转录物编码一种独特的胞质尾。其中的一个外显子的基因产物的特定的功能是未知的;然而，它们被认为在特定细胞 - 细胞的神经连接的建立和功能起关键作用。 [由RefSeq的，2008年7月提供]

PCDHB@基因在不同组织中的表达：    [UniProt]

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