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This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
[中文简述(自动翻译):]  该基因编码的氧固醇结合蛋白(OSBP)家族的一个成员,一组细胞内脂质受体。像大多数成员,编码的蛋白质含有N-末端普列克底物蛋白同源结构域和高度保守的C末端OSBP状固醇结合结构域。已发现该基因编码不同亚型的多个抄本变形。 [由RefSeq的,2010年3月提供]
OSBPL10基因(以及对应的蛋白质)的细胞分布位置:
OSBPL10基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Peripheral Arterial Diseases | 0.12 | 1 | 1 | GWASCAT |
Hyperlipidemia, Familial Combined | 0.002638474 | 1 | 0 | BeFree_GAD |
Peripheral Vascular Diseases | 0.002638474 | 1 | 0 | BeFree_GAD |
Dyslipidemias | 0.002638474 | 1 | 0 | BeFree_GAD |
Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
Vascular Diseases | 0.002367032 | 1 | 1 | GAD |
Metabolic Syndrome X | 0.000542884 | 2 | 0 | BeFree |
Hyperlipidemia | 0.000271442 | 1 | 0 | BeFree |
Liver neoplasms | 0.000271442 | 1 | 0 | BeFree |
Liver carcinoma | 0.000271442 | 1 | 0 | BeFree |
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