OPRL1(opiate receptor-like 1)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

20q13.33
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene is a G protein-coupled receptor whose expression can be induced by phytohemagglutinin. The encoded integral membrane protein is a receptor for the 17 aa neuropeptide nociceptin/orphanin FQ. This gene may be involved in the regulation of numerous brain activities, particularly instinctive and emotional behaviors. A promoter for this gene also functions as a promoter for another gene, regulator of G-protein signalling 19 (RGS19), located on the opposite strand. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2011]

[中文简述(自动翻译):]  由该基因编码的蛋白质是G蛋白偶联型受体的表达可通过植物血凝素诱导。所编码的完整的膜蛋白是17个氨基酸的神经肽痛敏肽/孤啡肽受体。该基因可能参与了无数的脑活动，特别是本能和情感行为的监管。一种用于此基因的启动子也充当另一个基因，G蛋白信号19（RGS19）的调节器，位于相反链上的启动子。已发现了该基因编码的蛋白质相同的三个抄本变形。 [由RefSeq的，2011年1月提供]

OMIM数据库中对OPRL1基因的介绍     Wikipedia数据库中对OPRL1基因的介绍

基因序列

基因序列

OPRL1基因的碱基序列：[NCBI]

基因突变

基因突变

OPRL1基因的碱基突变：           显示全部snp
rs4337532       rs4344972       rs4431000       rs4527258       rs6010717       rs6090043       rs6512305       rs41302948       rs76649929       rs77021907       rs78095308       rs112997674       rs116593761       rs138907471       rs139140910       rs139657511       rs140479432       rs141530489       rs142176694       rs142365377       rs143017973       rs143970092       rs144715439       rs145322546       rs147636148       rs148321107       rs148628225       rs151185653       rs180953847       rs181508720       rs183087832       rs185564067       rs189504034       rs192036354       rs369928040       rs372961279       rs374265183      
rs375975335       rs377744968       rs529743380       rs529928198       rs532377140       rs532442708       rs532465285       rs536169339       rs537022615       rs537105312       rs537693191       rs539068308       rs541721921       rs543509488       rs543635149       rs544653342       rs546045372       rs546780228       rs547313283       rs547432659       rs547479100       rs548283233       rs549440873       rs549694269       rs550542787       rs552471948       rs553276624       rs553669273       rs554881846       rs555074600       rs559238269       rs559643091       rs559786866       rs560944241       rs561896332       rs563496152       rs564046845       rs564280875       rs564491551       rs565958080       rs566046280       rs566909143       rs567198854       rs568449191       rs569943752       rs570004694       rs570586704       rs570674744       rs571976560       rs572576178       rs573103919       rs573443009       rs574324604       rs574948146       rs577114541       rs577122207       rs745638296       rs745746996       rs746318331       rs746750551       rs747374498       rs747635263       rs747774749       rs748763008       rs748814460       rs749379453       rs750220173       rs750226596       rs750558165       rs752019031       rs752073887       rs752290833       rs752880694       rs753785811       rs753910166       rs755222409       rs755347246       rs755402580       rs755866413       rs756392930       rs756712070       rs757078170       rs757309679       rs757740596       rs758190703       rs759166577       rs759353774       rs760292809       rs761803506       rs762151726       rs762504141       rs762691923       rs762892500       rs763105325       rs763156732       rs763630089       rs763668148       rs764149703       rs764266177       rs764319157       rs765136278       rs765218267       rs765302069       rs766099298       rs767016519       rs767190967       rs767753910       rs768331646       rs768411394       rs768464574       rs769819931       rs770105238       rs770848124       rs771454064       rs771832341       rs772524214       rs773032071       rs774064313       rs774169577       rs774220798       rs775015087       rs775233731       rs775285033       rs775398113       rs775421121       rs776347770       rs776432205       rs776730924       rs777403169       rs777886452       rs778516357       rs779319825       rs779391586       rs779448811       rs780743488       rs781361402       rs781567166       rs75908120       rs77765533       rs79406239       rs143190859       rs146168679       rs183443184       rs183805829       rs186614277       rs191305888       rs528268362       rs533258950       rs535688259       rs538109121       rs543449345       rs545874635       rs546652063       rs552188219       rs556056623       rs569584337       rs570706737       rs577017354       rs1059601       rs2229204       rs2229205       rs2229206       rs2295448       rs3003151       rs3215634       rs3764678       rs4377388       rs4519591       rs4809394       rs6010716       rs6010718       rs6010719       rs6010720       rs6010721       rs6011284       rs6011285       rs6011286       rs6011287       rs6011291       rs6011292       rs6011293       rs6089788       rs6089789       rs6090041       rs6090042       rs6122051       rs6122247       rs7271530       rs8121509       rs8126001       rs11905252       rs11907195       rs12106028       rs13043827       rs28403624       rs34874539       rs34879332       rs35872655       rs45465894       rs55715214       rs55872076       rs55884239       rs56270373       rs56306220       rs61742883       rs62218097       rs62218104       rs62218105       rs62218106       rs62218107       rs62218109       rs62218110       rs62218111       rs62218112       rs62218113       rs62218114       rs62218115       rs62218117       rs62218118       rs62218124       rs71197446       rs71197447       rs73151215       rs73151219       rs73322889       rs73324709       rs73916708       rs74216684       rs74222313       rs74668819       rs75023589       rs75074210       rs75078255       rs75368321       rs75452984       rs75622848       rs75730108       rs75751721       rs76424219       rs76487073       rs76806008       rs77084999       rs77165309       rs77312089       rs77461050       rs77981578       rs78388920       rs78514502       rs78791690       rs78828793       rs78839915       rs79244763       rs79351138       rs79781903       rs79805091       rs79879157       rs80271968       rs111351083       rs111354123       rs111495081       rs111600023       rs111625704       rs111663135       rs111854553       rs111890603       rs112228746       rs112244002       rs112253993       rs112318144       rs112428115       rs112475153       rs112564112       rs112698496       rs112737538       rs112825684       rs113037322       rs113199372       rs113407211       rs113541384       rs113573685       rs113706294       rs113735524       rs113847786       rs113922368       rs113943566       rs113997708       rs113999675       rs114004891       rs114319869       rs114634758       rs115066680       rs115647404       rs116079253       rs116347277       rs116532265       rs117204950       rs117235569       rs117765345       rs117908821       rs118081730       rs118117556       rs137950047       rs137978589       rs138017190       rs138210528       rs138320488       rs138338704       rs138440707       rs138688007       rs138878509       rs140038092       rs140080720       rs140385797       rs140550649       rs140620207       rs140843647       rs141090449       rs141282745       rs141283216       rs141501506       rs142615575       rs142618351       rs142621511       rs142778786       rs142892326       rs142906638       rs143380233       rs143480649       rs143653043       rs143748986       rs143757705       rs143798937       rs144065164       rs144338110       rs144582171       rs144606324       rs144800288       rs144823897       rs144923394       rs144979598       rs145287059       rs145759308       rs145773061       rs145840163       rs145896175       rs146045212       rs146054818       rs146075237       rs146581221       rs146611821       rs146834306       rs146923933       rs147164184       rs147180429       rs147804138       rs147864657       rs148060476       rs148381492       rs148484121       rs148514971       rs148535906       rs149018404       rs149301658       rs149714677       rs149756020       rs149935083       rs150184647       rs150300242       rs150491223       rs151122545       rs180973403       rs181242018       rs181294764       rs182155196       rs182974166       rs183437710       rs183698697       rs184628392       rs184799576       rs184953546       rs185091700       rs186260715       rs186580497       rs187084466       rs187450696       rs187608138       rs187988478       rs189105498       rs189599405       rs189641070       rs189794730       rs190433615       rs190674078       rs192507441       rs192704952       rs192715096       rs192983719       rs193083970       rs193158090       rs199525940       rs199586757       rs199646565       rs199664458       rs199794862       rs199975134       rs200138027       rs200326446       rs200476699       rs200485474       rs200495656       rs200577078       rs200634213       rs200646858       rs200881903       rs200930937       rs201752210       rs201903712       rs201975936       rs367711919       rs368400897       rs368968916       rs369457861       rs370134629       rs370204462       rs370715424       rs370852885       rs370858266       rs370985309       rs371142064       rs371386684       rs371848385       rs371951246       rs372237260       rs372320840       rs372366605       rs372839014       rs373552738       rs373721140       rs373942165       rs374016312       rs375054816       rs375250522       rs375434387       rs375458978       rs375635141       rs375779215       rs376089460       rs376128527       rs376564216       rs377227704       rs377466428       rs377675415       rs377711684       rs527381352       rs527517630       rs527603145       rs528139727       rs528523973       rs528610542       rs528908725       rs528918203       rs528958081       rs528970916       rs528992988       rs529088821       rs529369171       rs529386642       rs529401047       rs529498492       rs529551188       rs529637480       rs529828197       rs530031155       rs530159477       rs530534331       rs530564468       rs530863742       rs530984608       rs531053588       rs531179465       rs531225123       rs531237539       rs531259764       rs531383472       rs531574217       rs531633521       rs531998145       rs532441188       rs532584641       rs533127563       rs533259363       rs533394564       rs533462217       rs533479548       rs533725617       rs533773863       rs533857096       rs533926884       rs534055636       rs534361380       rs534578965       rs534588545       rs534873633       rs535157312       rs535270173       rs535304814       rs535328176       rs535486595       rs535549535       rs535612142       rs535797945       rs536629044       rs536712547       rs536856904       rs537084130       rs537110022       rs537228392       rs537290479       rs537311055       rs537895332       rs538304757       rs538616735       rs538672260       rs539093355       rs539157893       rs539157925       rs539473234       rs539476037       rs539500691       rs539836310       rs539856305       rs539899726       rs540099273       rs540146642       rs540226834       rs540480056       rs540695101       rs541222527       rs541614479       rs541684557       rs541814393       rs541945259       rs542047850       rs542740183       rs542859106       rs543075354       rs543249096       rs543325130       rs543625429       rs543676756       rs544169597       rs544182936       rs544490527       rs544515289       rs544591999       rs544747268       rs545660760       rs545751746       rs545886288       rs545938021       rs546175590       rs546281105       rs546491335       rs546563502       rs546576182       rs546700633       rs547004755       rs547040780       rs547162294       rs547345799       rs547562397       rs547700547       rs547824384       rs548327371       rs548423123       rs548638807       rs548706732       rs548762951       rs548940441       rs549175636       rs549546180       rs549560508       rs549727185       rs550197748       rs550205985       rs550318324       rs550550290       rs550769312       rs550949347       rs550998400       rs551028427       rs551104575       rs551154593       rs551158043       rs551172426       rs551282090       rs551760728       rs551901657       rs552285901       rs552753393       rs552819258       rs552993555       rs553042449       rs553088087       rs553130525       rs553765502       rs554164524       rs554284545       rs554739484       rs554766033       rs554827154       rs555139542       rs555160807       rs555251873       rs555523354       rs555534169       rs555544324       rs555764425       rs556144561       rs556592071       rs556726505       rs556995510       rs557069592       rs557268945       rs557528962       rs557543049       rs557632764       rs558085926       rs558216567       rs558223394       rs558482777       rs558899159       rs559037483       rs559115049       rs559241803       rs559286087       rs559454176       rs559578691       rs559678952       rs559861634       rs560256381       rs560436054       rs560588244       rs560702476       rs560876740       rs561059613       rs561086797       rs561152796       rs561456536       rs561827784       rs562037955       rs562130539       rs562291433       rs563033569       rs563120399       rs563363064       rs563422757       rs563577664       rs564092126       rs564153597       rs564462030       rs564630952       rs564809449       rs564894084       rs564973547       rs565030013       rs565415033       rs565431184       rs565431262       rs565453354       rs565491569       rs565615958       rs565652880       rs565791365       rs566032526       rs566154423       rs566168499       rs566212547       rs567137311       rs567411777       rs567429918       rs567595176       rs567773413       rs568172023       rs568284428       rs568288719       rs568291191       rs568422070       rs568517941       rs568597659       rs568683998       rs568813209       rs568908461       rs568911391       rs569312135       rs569359939       rs569557143       rs569620337       rs570030353       rs570459561       rs570990392       rs571062065       rs571078147       rs571117549       rs571388665       rs571454539       rs571519301       rs571917738       rs571949138       rs572571459       rs572645458       rs572958305       rs573021028       rs573061304       rs573091811       rs573858704       rs573864873       rs573924428       rs574180454       rs574256962       rs574712545       rs574712668       rs574800954       rs575028901       rs575041250       rs575178333       rs575178407       rs575181643       rs575261892       rs575290526       rs575515212       rs575648765       rs575974386       rs576005475       rs576329784       rs576467833       rs576600128       rs576735594       rs576735636       rs576993680       rs577019430       rs577020433       rs577114619       rs577508931       rs577521443       rs577992619       rs578045599       rs578196321       rs745375559       rs745570699       rs745624896       rs745704885       rs745726560       rs745934068       rs745943360       rs745988682       rs746201143       rs746548457       rs746614634       rs746845408       rs747565375       rs748126023       rs748465138       rs748531826       rs748597829       rs748761358       rs749016019       rs749282642       rs749635607       rs749661685       rs749985655       rs750004258       rs750208626       rs750611641       rs750838900       rs750859329       rs750893953       rs751069614       rs751075811       rs751386815       rs751635436       rs751713455       rs752006106       rs752227874       rs752502132       rs752591370       rs752611444       rs752880644       rs753097004       rs753197086       rs753365908       rs753546410       rs753624518       rs753661159       rs754188071       rs754309338       rs754400783       rs754701279       rs754782363       rs754819532       rs754982665       rs755011282       rs755034870       rs755066221       rs755251060       rs755536231       rs755638382       rs755874847       rs755983791       rs756175055       rs756382405       rs756544710       rs756713959       rs756805239       rs756968755       rs757482531       rs757687463       rs757799727       rs758308678       rs758399744       rs758467023       rs758586623       rs758599272       rs758694546       rs758794358       rs758847372       rs759062984       rs759099539       rs759118115       rs759823587       rs760237912       rs760357145       rs760977529       rs761398338       rs761519243       rs761551555       rs761748216       rs761987919       rs762398366       rs762466539       rs762573593       rs762717438       rs763105314       rs763622183       rs763764829       rs763834748       rs763850004       rs763960389       rs764059522       rs764187929       rs764583670       rs764836434       rs764893260       rs765876052       rs766421908       rs766542325       rs766908576       rs767051357       rs767058347       rs767233709       rs767554016       rs767590961       rs767698847       rs767720740       rs767753848       rs768088736       rs768146093       rs768181263       rs768295826       rs768432394       rs768943191       rs769120700       rs769147015       rs769344099       rs769560700       rs769614833       rs770079623       rs770136484       rs770154005       rs770191548       rs770273795       rs770542243       rs770672013       rs770725062       rs770852738       rs771493199       rs771661264       rs771696747       rs771898132       rs771974896       rs772476494       rs772654648       rs772932512       rs773033373       rs773088193       rs773412438       rs773698884       rs774009397       rs774067853       rs774114608       rs774239511       rs774642693       rs774683342       rs775123414       rs775178574       rs775205207       rs775816175       rs775933628       rs776074996       rs776675737       rs776817883       rs776959612       rs777047527       rs777074407       rs777327541       rs777936978       rs778094247       rs778178833       rs778324755       rs778663603       rs778913106       rs779080888       rs779141396       rs779277717       rs779484978       rs779538451       rs779780807       rs779804257       rs780019693       rs780063002       rs780072581       rs780562835       rs780688616       rs780823686       rs781195365       rs781248458       rs781308391       rs781489806       rs781578742       rs781620520       rs781666680      

基因表达

基因表达

OPRL1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TCGAGGATGAAGAGATCGAG
59
AGATGCAGATGGCAAACAC
59
GTCGAGGATGAAGAGATCGAG
60
GATGCAGATGGCAAACACC
60
GGTCGAGGATGAAGAGATCG
60
GATGCAGATGGCAAACACC
60
GTCGAGGATGAAGAGATCGAG
60
GATGCAGATGGCAAACACC
60
GGTCGAGGATGAAGAGATCG
60
GATGCAGATGGCAAACACC
60
TCGAGGATGAAGAGATCGAG
59
AGATGCAGATGGCAAACAC
59
TCGAGGATGAAGAGATCGAG
59
AGATGCAGATGGCAAACAC
59
GGTCGAGGATGAAGAGATCG
60
GATGCAGATGGCAAACACC
60
GTCGAGGATGAAGAGATCGAG
60
GATGCAGATGGCAAACACC
60

转录因子

转录因子

      尚未收录相关数据

基因本体信息

OPRL1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

OPRL1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001626
A0A0G2JQE4(UniProtKB)
IEA
GO:0016021
A0A0G2JQE4(UniProtKB)
IEA
GO:0038003
A0A0G2JQE4(UniProtKB)
IEA
GO:0038003
A0A0G2JQE4(UniProtKB)
IEA
GO:0001626
P41146(UniProtKB)
IDA
GO:0001934
P41146(UniProtKB)
IEA
GO:0004930
P41146(UniProtKB)
IGI
GO:0004930
P41146(UniProtKB)
IGI
GO:0004930
P41146(UniProtKB)
IGI
GO:0004930
P41146(UniProtKB)
IMP
GO:0005515
P41146(UniProtKB)
IPI
GO:0005886
P41146(UniProtKB)
TAS
GO:0005886
P41146(UniProtKB)
TAS
GO:0005886
P41146(UniProtKB)
TAS
GO:0005886
P41146(UniProtKB)
TAS
GO:0005887
P41146(UniProtKB)
IDA
GO:0005887
P41146(UniProtKB)
IDA
GO:0007193
P41146(UniProtKB)
IMP
GO:0007193
P41146(UniProtKB)
IMP
GO:0007204
P41146(UniProtKB)
IGI
GO:0007204
P41146(UniProtKB)
IGI
GO:0007204
P41146(UniProtKB)
IGI
GO:0007218
P41146(UniProtKB)
IBA
GO:0007268
P41146(UniProtKB)
IBA
GO:0007600
P41146(UniProtKB)
TAS
GO:0008022
P41146(UniProtKB)
IEA
GO:0016023
P41146(UniProtKB)
IEA
GO:0019233
P41146(UniProtKB)
ISS
GO:0019233
P41146(UniProtKB)
IBA
GO:0030818
P41146(UniProtKB)
IEA
GO:0032355
P41146(UniProtKB)
IEA
GO:0035810
P41146(UniProtKB)
IEA
GO:0038003
P41146(UniProtKB)
IEA
GO:0038003
P41146(UniProtKB)
IEA
GO:0042755
P41146(UniProtKB)
IEA
GO:0042923
P41146(UniProtKB)
IBA
GO:0043005
P41146(UniProtKB)
IBA
GO:0044849
P41146(UniProtKB)
IEA
GO:0045776
P41146(UniProtKB)
IEA
GO:0060454
P41146(UniProtKB)
IEA
GO:1901386
P41146(UniProtKB)
IEA
GO:1904058
P41146(UniProtKB)
IEA
GO:1904059
P41146(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控OPRL1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Cardiac Arrhythmia 0.12 1 0 CTD_human
Morphine Dependence 0.12 1 0 CTD_human
Substance Withdrawal Syndrome 0.12 1 0 CTD_human
Hypokinesia 0.12 1 0 CTD_human
Alcoholic Intoxication, Chronic 0.085276948 3 0 BeFree_GAD_RGD
Anorexia 0.08 1 0 RGD
Hyperalgesia 0.08 1 0 RGD
Hyperphagia 0.08 2 0 RGD
Sciatic Neuropathy 0.08 1 0 RGD
Opiate Addiction 0.002909916 2 0 BeFree_GAD
Opioid-Related Disorders 0.002367032 1 0 GAD
Substance-Related Disorders 0.002367032 1 0 GAD
Neuroblastoma 0.001085767 4 0 BeFree
Central neuroblastoma 0.001085767 4 0 BeFree
Hepatolenticular Degeneration 0.000271442 1 0 BeFree
Pain 0.000271442 1 0 BeFree
Post-Traumatic Stress Disorder 0.000271442 1 0 BeFree
Substance Dependence 0.000271442 1 0 BeFree
Absence of pain sensation 0.000271442 1 0 BeFree
Inflammatory disorder 0.000271442 1 0 BeFree
Drug Dependence 0.000271442 1 0 BeFree

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