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This gene encodes a member of the NADPH oxidase family of enzymes responsible for the catalytic one-electron transfer of oxygen to generate superoxide or hydrogen peroxide. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
[中文简述(自动翻译):]  该基因编码的NADPH氧化酶家族负责氧气的催化单电子转移,以??产生超氧化物或过氧化氢酶中的一员。编码多种亚型选择性剪接的转录物变体已经观察到这种基因。 [通过的RefSeq,2012十一月提供]
NOX1基因(以及对应的蛋白质)的细胞分布位置:
NOX1基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Colonic Neoplasms | 0.122995792 | 2 | 0 | BeFree_CTD_human_LHGDN |
Heart failure | 0.12 | 1 | 0 | CTD_human |
Hypercholesterolemia | 0.12 | 1 | 0 | CTD_human |
Hypertensive disease | 0.005991584 | 4 | 0 | BeFree_LHGDN |
Chronic granulomatous disease | 0.005720142 | 2 | 0 | BeFree_LHGDN |
Adenocarcinoma | 0.003267234 | 3 | 0 | BeFree_LHGDN |
Prostatic Neoplasms | 0.003267234 | 2 | 0 | BeFree_LHGDN |
Adenoma | 0.002995792 | 2 | 0 | BeFree_LHGDN |
Diabetic Nephropathy | 0.002995792 | 2 | 0 | BeFree_LHGDN |
Anoxia | 0.00272435 | 1 | 0 | LHGDN |
Atherosclerosis | 0.00272435 | 1 | 0 | LHGDN |
leukemia | 0.00272435 | 1 | 0 | LHGDN |
Pre-Eclampsia | 0.00272435 | 1 | 0 | LHGDN |
Diabetes Mellitus, Non-Insulin-Dependent | 0.002367032 | 1 | 0 | GAD |
HIV Infections | 0.002367032 | 1 | 0 | GAD |
Liver Cirrhosis | 0.002367032 | 1 | 0 | GAD |
Hepatopulmonary Syndrome | 0.002367032 | 1 | 0 | GAD |
Malignant tumor of colon | 0.001085767 | 4 | 0 | BeFree |
Malignant neoplasm of prostate | 0.001085767 | 4 | 0 | BeFree |
Prostate carcinoma | 0.000814326 | 3 | 0 | BeFree |
Colorectal Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Tumor Progression | 0.000542884 | 2 | 0 | BeFree |
Carcinogenesis | 0.000542884 | 2 | 0 | BeFree |
Colon Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Mammary Neoplasms | 0.000542884 | 2 | 0 | BeFree |
Colorectal Cancer | 0.000542884 | 2 | 0 | BeFree |
Cardiovascular Diseases | 0.000271442 | 1 | 0 | BeFree |
Colitis | 0.000271442 | 1 | 0 | BeFree |
Ulcerative Colitis | 0.000271442 | 1 | 0 | BeFree |
Amebic colitis | 0.000271442 | 1 | 0 | BeFree |
Gastritis, Atrophic | 0.000271442 | 1 | 0 | BeFree |
Glioblastoma | 0.000271442 | 1 | 0 | BeFree |
Immune System Diseases | 0.000271442 | 1 | 0 | BeFree |
Inflammatory Bowel Diseases | 0.000271442 | 1 | 0 | BeFree |
Retinal Diseases | 0.000271442 | 1 | 0 | BeFree |
Retinopathy of Prematurity | 0.000271442 | 1 | 0 | BeFree |
Septicemia | 0.000271442 | 1 | 0 | BeFree |
Vascular Diseases | 0.000271442 | 1 | 0 | BeFree |
Motor Neuron Disease | 0.000271442 | 1 | 1 | BeFree |
Essential Hypertension | 0.000271442 | 1 | 0 | BeFree |
Pancreatitis, Chronic | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma of lung (disorder) | 0.000271442 | 1 | 0 | BeFree |
Carcinoma, Signet Ring Cell | 0.000271442 | 1 | 0 | BeFree |
Pancreatic carcinoma | 0.000271442 | 1 | 0 | BeFree |
Fibrosis, Liver | 0.000271442 | 1 | 0 | BeFree |
Sepsis | 0.000271442 | 1 | 0 | BeFree |
Tumor necrosis | 0.000271442 | 1 | 0 | BeFree |
Spinocerebellar Ataxia Type 7 | 0.000271442 | 1 | 0 | BeFree |
Helicobacter pylori infection | 0.000271442 | 1 | 0 | BeFree |
Acral pseudolymphomatous angiokeratoma of children (APACHE) | 0.000271442 | 1 | 0 | BeFree |
Epithelioma | 0.000271442 | 1 | 0 | BeFree |
Tumor Angiogenesis | 0.000271442 | 1 | 0 | BeFree |
Severe Sepsis | 0.000271442 | 1 | 0 | BeFree |
Nasopharyngeal carcinoma | 0.000271442 | 1 | 0 | BeFree |
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