NCF1(neutrophil cytosolic factor 1) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

7q11.23
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质是嗜中性粒细胞NADPH氧化酶的47 kDa的胞质亚基。此氧化酶是活化以产生超氧阴离子的多组分酶。在这种基因突变与慢性肉芽肿病相关联。 [由RefSeq的，2008年7月提供]

OMIM数据库中对NCF1基因的介绍     Wikipedia数据库中对NCF1基因的介绍

基因序列

基因序列

NCF1基因的碱基序列：[NCBI]

基因突变

基因突变

NCF1基因的碱基突变：           显示全部snp
rs800977       rs800978       rs800979       rs800980       rs800981       rs997440       rs1637415       rs2465932       rs2523327       rs2523332       rs2528941       rs2529297       rs2539044       rs2718280       rs17356100       rs35067650       rs62475422       rs75207809       rs77875067       rs111979289       rs119103272       rs119103273       rs138054188       rs138406096       rs139225348       rs140034807       rs140463577       rs140969778       rs142050799       rs142480486       rs144018361       rs145170670       rs145360423       rs146125534       rs146173318       rs147659773       rs148767467      
rs181692881       rs181788842       rs182413790       rs185170050       rs190079672       rs199789198       rs199886863       rs199938434       rs200205449       rs200459715       rs200623471       rs200655630       rs200663210       rs200877252       rs201522178       rs201802880       rs202195500       rs367985113       rs368254704       rs368945669       rs369461764       rs369485834       rs370513174       rs371075194       rs372176579       rs372181124       rs373093123       rs373132324       rs373480987       rs373919021       rs374263357       rs374384176       rs375011835       rs375851395       rs376454321       rs376919169       rs377305075       rs377576524       rs377662255       rs587594457       rs587595128       rs587596880       rs587597258       rs587598319       rs587598401       rs587599110       rs587599132       rs587599860       rs587600267       rs587602527       rs587602716       rs587603740       rs587605880       rs587606175       rs587609606       rs587612525       rs587612790       rs587614686       rs587615323       rs587616286       rs587616925       rs587618080       rs587619899       rs587624473       rs587624953       rs587626004       rs587629774       rs587631811       rs587632076       rs587633477       rs587635992       rs587638476       rs587640002       rs587640770       rs587641181       rs587641296       rs587641317       rs587641644       rs587643499       rs587643599       rs587645677       rs587648376       rs587650231       rs587651844       rs587652150       rs587652529       rs587653076       rs587653999       rs587661330       rs587662134       rs587662513       rs587663099       rs587665386       rs587666154       rs587667464       rs587670140       rs587670182       rs587670410       rs587671809       rs587672878       rs587674298       rs587674714       rs587675858       rs587678620       rs587679141       rs587680541       rs587680627       rs587682397       rs587683486       rs587685954       rs587686615       rs587688058       rs587688879       rs587691787       rs587692394       rs587693328       rs587695222       rs587695598       rs587697744       rs587697982       rs587698529       rs587699309       rs587700704       rs587701795       rs587704690       rs587706878       rs587709073       rs587711107       rs587711470       rs587711972       rs587716074       rs587716514       rs587717510       rs587720481       rs587720716       rs587721998       rs587722819       rs587722945       rs587725433       rs587730054       rs587730414       rs587731308       rs587733352       rs587733564       rs587735115       rs587735189       rs587739768       rs587739881       rs587742807       rs587746171       rs587746334       rs587747270       rs587747870       rs587748583       rs587749538       rs587749584       rs587750876       rs587752120       rs587753749       rs587754645       rs587755234       rs587757490       rs587763288       rs587763821       rs587766030       rs587766077       rs587766712       rs587767903       rs587768074       rs587768315       rs587775181       rs587775915       rs781784127       rs781786233       rs781786929       rs781789430       rs781801935       rs781804912       rs781805772       rs781808663       rs781808976       rs781817519       rs781821575       rs781834627       rs781835731       rs781840733       rs781849042       rs781857646       rs781859571       rs781862114       rs781890686       rs781894224       rs781894954       rs781909474       rs781915784       rs781921509       rs781933814       rs781945357       rs781953146       rs781959708       rs781959928       rs781974943       rs781980620       rs781983704       rs781996787       rs782002877       rs782009050       rs782022363       rs782028515       rs782028894       rs782029909       rs782032278       rs782034034       rs782037135       rs782039216       rs782039400       rs782052125       rs782067165       rs782067600       rs782073447       rs782074398       rs782077045       rs782091728       rs782096268       rs782100556       rs782104553       rs782109262       rs782113541       rs782119877       rs782126215       rs782128694       rs782142500       rs782144307       rs782157090       rs782166417       rs782169559       rs782170312       rs782176450       rs782183721       rs782193656       rs782197230       rs782200934       rs782205505       rs782208737       rs782209678       rs782214627       rs782219576       rs782223424       rs782232664       rs782234231       rs782236954       rs782242537       rs782260476       rs782264937       rs782272331       rs782284699       rs782289015       rs782289802       rs782295551       rs782297857       rs782302035       rs782306577       rs782308134       rs782310642       rs782313991       rs782329551       rs782331439       rs782335665       rs782348351       rs782364575       rs782366860       rs782384491       rs782386704       rs782395518       rs782401143       rs782402177       rs782404949       rs782407343       rs782408014       rs782417498       rs782419776       rs782424535       rs782425656       rs782427361       rs782430982       rs782434810       rs782438868       rs782442373       rs782450062       rs782453617       rs782465451       rs782481752       rs782485806       rs782492205       rs782495977       rs782496561       rs782515324       rs782518527       rs782518889       rs782521032       rs782526868       rs782544408       rs782546882       rs782552650       rs782553526       rs782555266       rs782557413       rs782558908       rs782563385       rs782570759       rs782572273       rs782574958       rs782580709       rs782586627       rs782588016       rs782593576       rs782597081       rs782619739       rs782625469       rs782629025       rs782635646       rs782643879       rs782656910       rs782662118       rs782666062       rs782668137       rs782675140       rs782680047       rs782694259       rs782705862       rs782719350       rs782724139       rs782725904       rs782729459       rs782730949       rs782732294       rs782735248       rs782746861       rs782752617       rs782755612       rs782759739       rs782762643       rs782770241       rs782772203       rs782775114       rs782783154       rs782786186       rs782787740       rs782794682       rs782794889       rs782795751       rs782800778       rs782811610      

基因表达

基因表达

NCF1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AGCACTATGTGTACATGTTCC
58
TCGTAGATCTCGGTGAAGC
59
AGCACTATGTGTACATGTTCCT
60
TCGTAGATCTCGGTGAAGC
59
CTACGAGTTCCATGCATGAG
59
GCAGTGAGCTATGATTGCG
60
CATCAAGGCCTACACTGCT
60
TCGTCTTTCCTGATGACCC
59
TATGCAGGTGAGCCATACG
60
GAATGACCTCAACAGCTTCAC
60
TATGCAGGTGAGCCATACG
60
TCGTCTTTCCTGATGACCC
59
TGTTCCTGGTGAAATGGCA
60
TTATGGAACTCGTAGATCTCGG
59
TACTTGATGCCCAAAGATGG
58
TACGTCTGCAGGATGATGG
59
AGATGAAAGCAAAGCGAGG
59
TCGTCTTTCCTCAACAGCT
59
CATCAAGGCCTACACTGCT
60
TCGTCTTTCCTGATGACCC
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

NCF1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

NCF1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0035091
A0A087X1W0(UniProtKB)
IEA
GO:0005737
C9J155(UniProtKB)
IEA
GO:0016175
C9J155(UniProtKB)
IEA
GO:0035091
C9J155(UniProtKB)
IEA
GO:0055114
C9J155(UniProtKB)
IEA
GO:0035091
H7C1S1(UniProtKB)
IEA
GO:0002479
P14598(UniProtKB)
TAS
GO:0005515
P14598(UniProtKB)
IPI
GO:0005515
P14598(UniProtKB)
IPI
GO:0005515
P14598(UniProtKB)
IPI
GO:0005515
P14598(UniProtKB)
IPI
GO:0005515
P14598(UniProtKB)
IPI
GO:0005515
P14598(UniProtKB)
IPI
GO:0005515
P14598(UniProtKB)
IPI
GO:0005515
P14598(UniProtKB)
IPI
GO:0005515
P14598(UniProtKB)
IPI
GO:0005515
P14598(UniProtKB)
IPI
GO:0005515
P14598(UniProtKB)
IPI
GO:0005515
P14598(UniProtKB)
IPI
GO:0005829
P14598(UniProtKB)
IDA
GO:0005829
P14598(UniProtKB)
TAS
GO:0005829
P14598(UniProtKB)
TAS
GO:0005829
P14598(UniProtKB)
TAS
GO:0005829
P14598(UniProtKB)
TAS
GO:0005829
P14598(UniProtKB)
TAS
GO:0006612
P14598(UniProtKB)
IDA
GO:0006801
P14598(UniProtKB)
TAS
GO:0006968
P14598(UniProtKB)
TAS
GO:0009055
P14598(UniProtKB)
TAS
GO:0016175
P14598(UniProtKB)
IMP
GO:0017124
P14598(UniProtKB)
IPI
GO:0017124
P14598(UniProtKB)
IPI
GO:0019898
P14598(UniProtKB)
IDA
GO:0032010
P14598(UniProtKB)
TAS
GO:0032010
P14598(UniProtKB)
TAS
GO:0032010
P14598(UniProtKB)
TAS
GO:0035091
P14598(UniProtKB)
IDA
GO:0042554
P14598(UniProtKB)
IMP
GO:0042554
P14598(UniProtKB)
TAS
GO:0043020
P14598(UniProtKB)
IDA
GO:0043020
P14598(UniProtKB)
TAS
GO:0043325
P14598(UniProtKB)
IDA
GO:0045087
P14598(UniProtKB)
TAS
GO:0045454
P14598(UniProtKB)
TAS
GO:0045730
P14598(UniProtKB)
TAS
GO:0048010
P14598(UniProtKB)
TAS
GO:0055114
P14598(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控NCF1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type I 0.44 1 5 CLINVAR_CTD_human_MGD_UNIPROT
Chronic granulomatous disease 0.137839219 58 0 BeFree_GAD_ORPHANET
Hypertensive disease 0.121357209 7 0 BeFree_CTD_human
Rheumatoid Arthritis 0.120814326 4 0 BeFree_CTD_human
Diabetes Mellitus 0.120542884 3 0 BeFree_CTD_human
Neoplastic Cell Transformation 0.12 1 0 CTD_human
Intracranial Aneurysm 0.12 1 0 CTD_human
Diabetes Mellitus, Experimental 0.12 2 0 CTD_human
Hypercholesterolemia 0.12 1 0 CTD_human
Kidney Failure, Chronic 0.12 1 0 CTD_human
Aortic Aneurysm, Abdominal 0.12 1 0 CTD_human
Arthritis, Experimental 0.08 1 0 RGD
Multiple Sclerosis 0.005362824 2 0 BeFree_GAD_LHGDN
Malaria, Falciparum 0.005091382 1 0 GAD_LHGDN
Arthritis 0.003528744 13 0 BeFree
Ectodermal Dysplasia 0.00272435 1 0 LHGDN
Cerebral Infarction 0.002367032 1 0 GAD
Cerebrovascular accident 0.002367032 1 0 GAD
Williams Syndrome 0.001357209 5 0 BeFree
Autoimmune Diseases 0.000542884 2 0 BeFree
Diabetes 0.000542884 2 0 BeFree
Encephalomyelitis 0.000542884 2 0 BeFree
Experimental Autoimmune Encephalomyelitis 0.000542884 2 0 BeFree
Arthritis, Collagen-Induced 0.000542884 2 0 BeFree
Autosomal Recessive Chronic Granulomatous Disease 0.000542884 2 0 BeFree
Alzheimer's Disease 0.000271442 1 0 BeFree
Anemia, Sickle Cell 0.000271442 1 0 BeFree
Blast Phase 0.000271442 1 0 BeFree
Bloom Syndrome 0.000271442 1 0 BeFree
Cardiovascular Diseases 0.000271442 1 0 BeFree
Colitis 0.000271442 1 0 BeFree
Crohn Disease 0.000271442 1 0 BeFree
Dengue Fever 0.000271442 1 0 BeFree
Diabetic Nephropathy 0.000271442 1 0 BeFree
Escherichia coli Infections 0.000271442 1 0 BeFree
Heart failure 0.000271442 1 0 BeFree
Congestive heart failure 0.000271442 1 0 BeFree
Immunologic Deficiency Syndromes 0.000271442 1 0 BeFree
Kidney Diseases 0.000271442 1 0 BeFree
Liver Abscess 0.000271442 1 0 BeFree
Lupus Erythematosus, Systemic 0.000271442 1 0 BeFree
Lymphoma 0.000271442 1 0 BeFree
Malaria 0.000271442 1 0 BeFree
Mycoses 0.000271442 1 0 BeFree
Myeloproliferative disease 0.000271442 1 0 BeFree
Obesity 0.000271442 1 0 BeFree
Parasitic Diseases 0.000271442 1 0 BeFree
Phenylketonurias 0.000271442 1 0 BeFree
Pulmonary Edema 0.000271442 1 0 BeFree
Septicemia 0.000271442 1 0 BeFree
Severe Combined Immunodeficiency 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lung 0.000271442 1 0 BeFree
Memory impairment 0.000271442 1 0 BeFree
Sepsis 0.000271442 1 0 BeFree
Rhinovirus infection 0.000271442 1 0 BeFree
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site 0.000271442 1 0 BeFree
Malignant neoplasm of prostate 0.000271442 1 0 BeFree
Hyper-IgM Immunodeficiency Syndrome, Type 1 0.000271442 1 0 BeFree
Overweight 0.000271442 1 0 BeFree
X-Linked Lymphoproliferative Disorder 0.000271442 1 0 BeFree
Prostate carcinoma 0.000271442 1 0 BeFree
Parasitic infection 0.000271442 1 0 BeFree
Chronic myeloproliferative disorder 0.000271442 1 0 BeFree
Classical Hodgkin's Lymphoma 0.000271442 1 0 BeFree
Ectodermal dysplasia, hypohidrotic, with immune deficiency 0.000271442 1 0 BeFree
ZAP70 deficiency 0.000271442 1 0 BeFree

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