MTHFR(methylenetetrahydrofolate reductase (NAD(P)H)) 转至新版数据库

基因简称(symbol)

MTHFR [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

基因家族代码(gene_family_id)

[HGNC] [GenScript]

omim代码

607093

entrez码

4524 [Vega]

vega基因码

OTTHUMG00000002277

ensembl基因码

ENSG00000177000 [Ensembl]

基因家族(gene family)

refseq数据库代号

NM_005957

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

01p36.3

同源基因名称(alias name)

基因名称批准使用时间(date_approved_reserved)

1994-07-15T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

2010-05-04T00:00:00Z

更新时间(date_modified)

2015-04-22T00:00:00Z

ucsc码

uc001atc.2

ena

BC053509

ccds数据码

CCDS137

uniprot数据码

P42898

pubmed代码

7920641

mgd码

MGI:106639

rgd码

RGD:1309952

生命科学数据库(lsdb)

LRG_726|http://www.lrg-sequence.org/LRG/LRG_726

更新时间(date modified)

2015-04-22T00:00:00Z

cosmic

MTHFR

mirbase

基因曾用简称(prev symbol)

基因曾用名称(prev name)

5,10-methylenetetrahydrofolate reductase (NADPH)

homeodb

cosmic

MTHFR

snornabase

bioparadigms slc

orphanet

123529

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

LncRNA数据库

酶代码

1.5.1.20

中间纤维数据库

收起

1p36.3

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009]

[中文简述(自动翻译):] 由该基因编码的蛋白质催化5,10-亚甲基四氢叶酸向5-甲基，共底物高半胱氨酸remethylation到甲硫氨酸的转换。这种基因影响易感性的遗传变异为闭塞性血管疾病，神经管畸形，结肠癌和急性白血病，而且突变这个基因与甲基四氢叶酸还原酶缺乏有关。[由RefSeq的，2009年10月提供]

OMIM数据库中对MTHFR基因的介绍 Wikipedia数据库中对MTHFR基因的介绍

MTHFR基因的碱基序列：[NCBI]

MTHFR基因的碱基突变：显示全部snp

rs15854 rs868014 rs915014 rs1057624 rs1537514 rs1537515 rs1537516 rs2077360 rs2151654 rs2151655 rs2184226 rs2184227 rs3737966 rs3737967 rs3820192 rs4845884 rs4846048 rs11559040 rs12023469 rs34733339 rs35134728 rs35562212 rs41275468 rs45445997 rs45451599 rs45574135 rs55740775 rs59375726 rs60350681 rs70983598 rs72640221 rs74053317 rs76404992 rs111375163 rs112141230 rs112469003 rs112976388

rs113958691 rs114290429 rs114646114 rs114673809 rs116013353 rs116698217 rs138288803 rs138526324 rs141481256 rs142369131 rs142884651 rs143100671 rs144054436 rs144624195 rs147946793 rs149055513 rs149920033 rs150449128 rs182398073 rs183631107 rs184025389 rs185982649 rs186662631 rs188149872 rs188514323 rs188657034 rs189783792 rs191460937 rs191871636 rs192238519 rs193231767 rs200822442 rs369053847 rs369313497 rs369609825 rs371188005 rs371980324 rs372468963 rs372788905 rs372869912 rs373252979 rs374047798 rs374660279 rs375481053 rs397709443 rs527656604 rs527742848 rs528653413 rs528746603 rs528831502 rs530644920 rs530706948 rs531284429 rs533310380 rs533406308 rs533425321 rs533874353 rs534045485 rs534760603 rs536268618 rs536599088 rs537270036 rs537306768 rs537668565 rs538074274 rs539472116 rs539477910 rs539755675 rs540922358 rs540959127 rs542140204 rs542177264 rs543936102 rs544692675 rs544830292 rs545991628 rs546502055 rs546580031 rs547557995 rs548412009 rs549710861 rs550133360 rs551486571 rs552288811 rs552327453 rs552663617 rs553174802 rs553378191 rs553529153 rs553811159 rs554565392 rs555102130 rs555188130 rs555815683 rs556288170 rs557355095 rs558100195 rs559445854 rs560051837 rs560319585 rs560655248 rs561382029 rs561469824 rs562305112 rs562389867 rs562859148 rs563513836 rs563550540 rs564348925 rs564466007 rs564957831 rs565962962 rs566155977 rs566373681 rs566663800 rs566853939 rs568579504 rs569629260 rs569819222 rs570036952 rs570545683 rs571383705 rs572143295 rs573066823 rs574354244 rs575577732 rs576221376 rs577635601 rs578111853 rs746048298 rs746603471 rs747078351 rs747705929 rs748486375 rs748561255 rs748705522 rs748870451 rs748948331 rs749661442 rs750033466 rs750555459 rs751130740 rs751714928 rs752517980 rs753152096 rs753706728 rs754883533 rs754937889 rs755339389 rs755383372 rs755865052 rs755921837 rs758358400 rs759766598 rs760756415 rs761866671 rs762678203 rs763465988 rs763508209 rs764231951 rs765145709 rs767153383 rs768245863 rs770052934 rs770326136 rs770536637 rs771138234 rs771645573 rs773140384 rs773185522 rs773814238 rs774290705 rs775118437 rs775380089 rs776374746 rs777353108 rs778397302 rs778861331 rs779427716 rs780544847 rs781062180 rs3737964 rs3737965 rs3753582 rs3753583 rs3753584 rs3753585 rs3753586 rs3753587 rs3834043 rs3834044 rs3834045 rs7555034 rs7555471 rs13306557 rs13306560 rs13306561 rs17037420 rs17367629 rs34591652 rs45440899 rs45460391 rs45486493 rs45498791 rs45504095 rs45543733 rs45558742 rs45594036 rs45610837 rs56221660 rs71568356 rs76351797 rs76378492 rs77130610 rs77612924 rs111334345 rs111776518 rs111800209 rs113721804 rs114893690 rs115986455 rs116823863 rs139107857 rs139504891 rs140859848 rs142234351 rs143022405 rs144355693 rs146516967 rs149702748 rs150143694 rs150673285 rs182541220 rs183257412 rs185998105 rs186269272 rs186455079 rs189293893 rs190711225 rs192511521 rs199831015 rs200063388 rs200524870 rs201017022 rs201666128 rs368901338 rs369972988 rs370646327 rs371096204 rs372389617 rs373838997 rs373983779 rs375627424 rs377627467 rs377693406 rs397726051 rs397897501 rs527412636 rs528001577 rs529177331 rs531431386 rs531468301 rs532104620 rs532967437 rs533051829 rs533644790 rs534367778 rs534679637 rs537851426 rs540042456 rs540347295 rs541096772 rs542768587 rs542929083 rs543564275 rs543601106 rs544243561 rs544956163 rs545353184 rs545851519 rs547509274 rs548999915 rs550481493 rs551238982 rs551399405 rs553069000 rs554135391 rs554876264 rs555448313 rs555535290 rs556168899 rs558358450 rs558706402 rs559157796 rs560969189 rs561055225 rs562529887 rs567251296 rs567502044 rs568326346 rs569976647 rs571241565 rs571676971 rs571697213 rs572291283 rs572383997 rs573377967 rs574949108 rs577552705 rs745834239 rs746991024 rs748884475 rs751462670 rs751939664 rs752842955 rs752992918 rs753976878 rs755062572 rs755256371 rs755554098 rs756135466 rs757134976 rs757330818 rs758081891 rs759262209 rs759311450 rs760087354 rs761207554 rs764096461 rs764522149 rs765379751 rs766813777 rs767856435 rs767943876 rs769436718 rs769631586 rs770314628 rs770543299 rs773689397 rs774969122 rs776321884 rs777072090 rs777127139 rs778935082 rs779651762 rs780153104 rs780487177 rs781211840 rs1413355 rs1476413 rs1572151 rs1801131 rs1801133 rs1931226 rs1994798 rs2066461 rs2066462 rs2066463 rs2066464 rs2066465 rs2066466 rs2066467 rs2066468 rs2066469 rs2066470 rs2066471 rs2066472 rs2274973 rs2274974 rs2274975 rs2274976 rs3753588 rs3766747 rs3818762 rs3927589 rs4845885 rs4846048 rs4846049 rs4846050 rs4846051 rs4846052 rs5772477 rs6541003 rs6541004 rs6541005 rs6541006 rs6664734 rs6681229 rs6700268 rs7518348 rs7525338 rs7526128 rs7527897 rs7533315 rs7535669 rs7537955 rs7545331 rs7547068 rs7553194 rs9651118 rs11121832 rs12121543 rs12403856 rs13306553 rs13306554 rs13306555 rs13306556 rs13306558 rs13306559 rs13306567 rs17037388 rs17037390 rs17037396 rs17037397 rs17037404 rs17367504 rs17375901 rs17421462 rs17421511 rs17421560 rs34279942 rs34450350 rs34825967 rs34840945 rs34846084 rs34889587 rs35464336 rs35529390 rs35593468 rs35653697 rs35737219 rs36015380 rs36040334 rs41394446 rs41452445 rs45438591 rs45439601 rs45444794 rs45449298 rs45449597 rs45449894 rs45451799 rs45459991 rs45468191 rs45475403 rs45479906 rs45480996 rs45482794 rs45483798 rs45486194 rs45495691 rs45496998 rs45497396 rs45498098 rs45501993 rs45504202 rs45504491 rs45507491 rs45510994 rs45515599 rs45515693 rs45518732 rs45525433 rs45525835 rs45528432 rs45529133 rs45530331 rs45532338 rs45533333 rs45539035 rs45546035 rs45549136 rs45550133 rs45553335 rs45558433 rs45560334 rs45568839 rs45568845 rs45571736 rs45572531 rs45577533 rs45577937 rs45578832 rs45578836 rs45589033 rs45589544 rs45590836 rs45598534 rs45599731 rs45602238 rs45603435 rs45606635 rs45608437 rs45622739 rs45622745 rs45625835 rs55645287 rs55686944 rs55898207 rs56182143 rs70983601 rs70983602 rs71492358 rs71568355 rs72552099 rs72640233 rs74683406 rs74826820 rs76210458 rs77078602 rs79157191 rs79511568 rs80038130 rs80307360 rs111541538 rs111705920 rs111847924 rs111872338 rs112100966 rs112329381 rs112371828 rs113040068 rs113270830 rs113378628 rs113518012 rs113615972 rs113950672 rs113989925 rs115049252 rs115558910 rs115670597 rs115931610 rs116371083 rs116578084 rs116620395 rs116951275 rs121434295 rs121434296 rs121434297 rs137896923 rs138112017 rs138189536 rs138469955 rs138524217 rs138628145 rs138748774 rs138760604 rs139586522 rs139645527 rs139786244 rs140241283 rs140277700 rs140496402 rs140565495 rs140828780 rs141060174 rs141237767 rs141425868 rs141769179 rs141798303 rs141819485 rs142122906 rs142612062 rs142617551 rs143142879 rs143205066 rs143347952 rs143428827 rs143466425 rs143480693 rs143764348 rs144508139 rs144594875 rs144704179 rs144920629 rs144921426 rs145052308 rs145210863 rs145253240 rs145302631 rs145381829 rs145544233 rs145641996 rs146025831 rs146359120 rs146554888 rs146853839 rs147257424 rs147409791 rs147727428 rs147750177 rs147883027 rs147979890 rs149064073 rs149278646 rs149514973 rs149533586 rs149585376 rs150060894 rs150246202 rs150847674 rs150870770 rs150963282 rs151151076 rs181147408 rs181739295 rs181792206 rs181992623 rs182199605 rs182261953 rs183117221 rs183413973 rs183742250 rs183893148 rs184507441 rs184703680 rs184994657 rs185234243 rs186197396 rs186378656 rs186667599 rs186889299 rs186916207 rs187644747 rs187902563 rs187974634 rs189021156 rs189050143 rs189291356 rs189798757 rs190046545 rs190087897 rs190090719 rs190957437 rs191642688 rs192369602 rs192680314 rs192863973 rs192995855 rs199517455 rs199692771 rs199707466 rs199730437 rs199787735 rs199822652 rs199974820 rs200056619 rs200100285 rs200137991 rs200138092 rs200180238 rs200331082 rs200350598 rs200379144 rs200409344 rs200688214 rs200771471 rs200789362 rs200890679 rs200892006 rs200947520 rs201006287 rs201095365 rs201105692 rs201161651 rs201401275 rs201618781 rs201660904 rs201696223 rs201698816 rs201780607 rs201888750 rs202095816 rs202153689 rs367589095 rs367730971 rs367992906 rs368049152 rs368321176 rs368379302 rs368586552 rs368670947 rs368735885 rs368918767 rs368987205 rs369203150 rs369259702 rs369283762 rs369386665 rs369761897 rs369800966 rs369851718 rs369897291 rs370007225 rs370138406 rs370272345 rs370276497 rs370355007 rs370416848 rs370541764 rs370646345 rs370713424 rs370795291 rs370996045 rs371085894 rs371825458 rs371829068 rs372125653 rs372141207 rs372258648 rs372969871 rs373009214 rs373076763 rs373138974 rs373249606 rs373328611 rs373398993 rs373524607 rs373747884 rs374026519 rs374247963 rs374293757 rs374433935 rs374472468 rs374473936 rs374497616 rs374533009 rs374611237 rs374747214 rs374867280 rs374930926 rs375119199 rs375212771 rs375335932 rs375487601 rs375607927 rs375686262 rs375817840 rs376040746 rs376266183 rs376616918 rs376833963 rs376927238 rs377443637 rs377571071 rs377635370 rs397897566 rs397979240 rs527473639 rs527493223 rs527544441 rs528098878 rs528136979 rs528636301 rs529675108 rs529901408 rs529907129 rs530166393 rs530250174 rs530334239 rs530444676 rs530478985 rs530674219 rs531032710 rs531062987 rs531469522 rs531577946 rs531914270 rs532267156 rs533386804 rs533671110 rs534517391 rs534528478 rs535031309 rs535031372 rs535068759 rs535412180 rs535781837 rs536307182 rs536341280 rs536741787 rs536781350 rs537454111 rs537540533 rs537577077 rs537939979 rs538151997 rs538188982 rs538647292 rs538649080 rs538737297 rs538774885 rs538774996 rs538862503 rs538946474 rs539217684 rs539259350 rs539357516 rs539388566 rs539716732 rs539809148 rs539847811 rs539848119 rs539932473 rs540834487 rs541108361 rs541233218 rs541324392 rs541364916 rs541505625 rs541668973 rs541755494 rs541892280 rs542060620 rs542140184 rs542491457 rs543016186 rs543427518 rs543688861 rs543774481 rs543808715 rs544367623 rs544453501 rs544643990 rs544798775 rs545002537 rs545086633 rs545359407 rs545440217 rs545595795 rs545690093 rs545952776 rs546298964 rs546509565 rs546724401 rs546765286 rs547183271 rs547241913 rs547372308 rs547458016 rs547496119 rs547520987 rs547574100 rs547583387 rs547923475 rs548087160 rs548125565 rs548212764 rs548547873 rs548725605 rs549206711 rs549961827 rs550000458 rs550394889 rs550475553 rs550744749 rs550873014 rs551040568 rs551242201 rs551326033 rs551974998 rs552116958 rs552496639 rs552646135 rs552703655 rs552925243 rs553126835 rs553322682 rs553635476 rs553844323 rs553869972 rs553904244 rs553906224 rs553996815 rs554668389 rs554788111 rs555061953 rs555063475 rs555100245 rs555105118 rs555458447 rs555926917 rs555964132 rs556050585 rs556432785 rs556653513 rs556845239 rs556912569 rs557070205 rs557158257 rs557358780 rs557445152 rs557447398 rs557618060 rs558230616 rs558759895 rs558910173 rs559189829 rs559501574 rs559620102 rs560915406 rs560982435 rs561139839 rs561164496 rs561724361 rs562174847 rs562454685 rs562572831 rs562933439 rs563009978 rs563388466 rs563544729 rs563755549 rs563779020 rs563840479 rs563865923 rs563926764 rs564044296 rs564397537 rs564615502 rs564703436 rs564791198 rs565031840 rs565066141 rs565087518 rs565116610 rs565127910 rs565197473 rs565200419 rs565525805 rs565665022 rs565879486 rs565921519 rs566125423 rs566398632 rs566402690 rs566402876 rs566437210 rs566478202 rs567356444 rs567863653 rs567912003 rs568433069 rs568688313 rs568817014 rs569229242 rs569658202 rs570048078 rs570056767 rs570103642 rs570141592 rs570256772 rs570347512 rs570866098 rs570966146 rs571224961 rs571238208 rs571324372 rs571580835 rs571580991 rs571616133 rs572171405 rs572253564 rs572292225 rs572344740 rs572688649 rs572816626 rs573418694 rs573538296 rs574132670 rs574157712 rs574218820 rs574486176 rs574716638 rs574915221 rs574984197 rs575375057 rs575895721 rs576337810 rs576446829 rs576485125 rs576853093 rs577135269 rs577169975 rs577171778 rs577634830 rs578166623 rs745342367 rs745437278 rs745497522 rs745716822 rs745779146 rs745796904 rs745832174 rs745996254 rs746019336 rs746072230 rs746177570 rs746327818 rs746353274 rs746368113 rs746380785 rs746937239 rs747030821 rs747129811 rs747182653 rs747207640 rs747239865 rs747447307 rs747470767 rs747501037 rs747554082 rs747665983 rs747668376 rs747712448 rs747846362 rs747938592 rs747993832 rs748104181 rs748112566 rs748289202 rs748397580 rs748571395 rs748601308 rs748686763 rs748688171 rs748894307 rs748977409 rs749165790 rs749229159 rs749267753 rs749427873 rs749442724 rs749490263 rs749532075 rs749606539 rs749729349 rs749762143 rs749765738 rs749819150 rs750001667 rs750053102 rs750272108 rs750288224 rs750323424 rs750339037 rs750376296 rs750478921 rs750505337 rs750510348 rs750559647 rs750661990 rs750677509 rs750818024 rs750866106 rs750884113 rs750895059 rs751044729 rs751138401 rs751268792 rs751357547 rs751410976 rs751448957 rs751512280 rs751597875 rs751995483 rs752039471 rs752085096 rs752143951 rs752303359 rs752411454 rs752576846 rs752585350 rs752586512 rs752891093 rs752911686 rs752994506 rs753049408 rs753167474 rs753278299 rs753329261 rs753424131 rs753485177 rs753547326 rs753692902 rs753697556 rs753706584 rs753730796 rs753750547 rs753917964 rs754015864 rs754122249 rs754191043 rs754337801 rs754393264 rs754425084 rs754554624 rs754579302 rs754589656 rs754948861 rs754971821 rs754980119 rs755060313 rs755181257 rs755269695 rs755483936 rs755706546 rs755757932 rs755829023 rs755932312 rs755932641 rs756018487 rs756032462 rs756165045 rs756181184 rs756234498 rs756481226 rs756615138 rs756691180 rs756891371 rs756944555 rs756946072 rs756962297 rs756994487 rs757138144 rs757215390 rs757268352 rs757269213 rs757315222 rs757497217 rs757550872 rs757627437 rs757629473 rs757733135 rs757748747 rs757784497 rs757868254 rs758146947 rs758206023 rs758413827 rs758745762 rs759031330 rs759262119 rs759367609 rs759381630 rs759424846 rs759442571 rs759745583 rs759796920 rs759835987 rs760081535 rs760161369 rs760272809 rs760349899 rs760355106 rs760359639 rs760378726 rs760525041 rs760548974 rs760570032 rs760616536 rs760722342 rs760886915 rs760971509 rs760971789 rs761059422 rs761106316 rs761226286 rs761230732 rs761392430 rs761492399 rs761540678 rs761545364 rs761705206 rs761733008 rs761788073 rs761795803 rs761849115 rs761870682 rs761916311 rs761926041 rs762279000 rs762403278 rs762581197 rs762599135 rs762663885 rs762688654 rs762719063 rs762751084 rs762875346 rs762878532 rs762926819 rs763116318 rs763185082 rs763186690 rs763266527 rs763419970 rs763476837 rs763539350 rs763564869 rs763699944 rs763747377 rs763881351 rs763896620 rs763953323 rs764131110 rs764338697 rs764444752 rs764455987 rs764524250 rs764650203 rs764655005 rs764660121 rs764839255 rs765043361 rs765167328 rs765257406 rs765418847 rs765500188 rs765586205 rs765619217 rs765625943 rs765736104 rs765787903 rs765794234 rs765794603 rs765834557 rs765893664 rs765899301 rs765930342 rs766069149 rs766092654 rs766242179 rs766295185 rs766350327 rs766373809 rs766410193 rs766488005 rs766683363 rs766741086 rs766867793 rs766958171 rs767023152 rs767171125 rs767306503 rs767347807 rs767416289 rs767608041 rs767789270 rs767804837 rs767890671 rs767978632 rs768081446 rs768248826 rs768349356 rs768416903 rs768434408 rs768579620 rs768611976 rs768630799 rs768756008 rs768777831 rs768853678 rs768873896 rs768905024 rs768932563 rs769258023 rs769381688 rs769476355 rs769592994 rs769609516 rs769659626 rs769778830 rs769916813 rs769953411 rs770097961 rs770121656 rs770151367 rs770407631 rs770413328 rs770418535 rs770471347 rs770598294 rs770611205 rs770648394 rs770670302 rs770793658 rs770922488 rs771090648 rs771191316 rs771375720 rs771601940 rs771607338 rs771684838 rs771782125 rs771802611 rs771854010 rs771960561 rs772127190 rs772252042 rs772317566 rs772615731 rs772660718 rs772698730 rs772769496 rs772858015 rs772932189 rs772990455 rs773159240 rs773214376 rs773336859 rs773360881 rs773410203 rs773463208 rs773527571 rs773599133 rs773652460 rs774051572 rs774066396 rs774104819 rs774118546 rs774169608 rs774321998 rs774377137 rs774513066 rs774531580 rs774623396 rs774637461 rs774681018 rs774694621 rs774696322 rs774825800 rs774934088 rs775066323 rs775136816 rs775190420 rs775190597 rs775245791 rs775254308 rs775304282 rs775507432 rs775829502 rs775917722 rs775972969 rs776034726 rs776084278 rs776182425 rs776195746 rs776289670 rs776376908 rs776430173 rs776483190 rs776567780 rs776606131 rs776734688 rs776842392 rs776862280 rs776875610 rs776901659 rs776956662 rs776969786 rs777084035 rs777218363 rs777286995 rs777304472 rs777367515 rs777635153 rs777661576 rs777803896 rs777858766 rs777918196 rs777964050 rs777984663 rs778011870 rs778308636 rs778353903 rs778417385 rs778486116 rs778531212 rs778569672 rs778682219 rs778716054 rs778825744 rs778878133 rs778887074 rs778983789 rs779036861 rs779138021 rs779519388 rs779574397 rs779574587 rs779627394 rs779696019 rs779868531 rs779993607 rs780005836 rs780014899 rs780044835 rs780070182 rs780175913 rs780207553 rs780279740 rs780382245 rs780544969 rs780551872 rs780598209 rs780701935 rs780711805 rs780767010 rs781052101 rs781158269 rs781183389 rs781214043 rs781229410 rs781332162 rs781388555 rs781419948 rs781534754 rs781590734 rs781673340 rs781742574

MTHFR基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

尚未收录相关数据

MTHFR基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

MTHFR基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0001666

P42898(UniProtKB)

IEA

GO:0004489

P42898(UniProtKB)

IGI

GO:0004489

P42898(UniProtKB)

IDA

GO:0004489

P42898(UniProtKB)

IMP

GO:0004489

P42898(UniProtKB)

IDA

GO:0004489

P42898(UniProtKB)

IMP

GO:0004489

P42898(UniProtKB)

TAS

GO:0005829

P42898(UniProtKB)

IBA

GO:0005829

P42898(UniProtKB)

TAS

GO:0006520

P42898(UniProtKB)

TAS

GO:0006555

P42898(UniProtKB)

IGI

GO:0008015

P42898(UniProtKB)

TAS

GO:0031060

P42898(UniProtKB)

IDA

GO:0032403

P42898(UniProtKB)

IPI

GO:0033274

P42898(UniProtKB)

IEA

GO:0035999

P42898(UniProtKB)

IEA

GO:0035999

P42898(UniProtKB)

IGI

GO:0035999

P42898(UniProtKB)

IDA

GO:0035999

P42898(UniProtKB)

IMP

GO:0035999

P42898(UniProtKB)

IMP

GO:0042493

P42898(UniProtKB)

IEA

GO:0043005

P42898(UniProtKB)

IEA

GO:0046500

P42898(UniProtKB)

IEA

GO:0046655

P42898(UniProtKB)

TAS

GO:0050660

P42898(UniProtKB)

IDA

GO:0050661

P42898(UniProtKB)

IEA

GO:0050667

P42898(UniProtKB)

IDA

GO:0051593

P42898(UniProtKB)

IEA

GO:0055114

P42898(UniProtKB)

IEA

GO:0070555

P42898(UniProtKB)

IEA

GO:0070829

P42898(UniProtKB)

IDA

GO:0072341

P42898(UniProtKB)

IDA

GO:0004489

Q5SNW5(UniProtKB)

IEA

GO:0006555

Q5SNW5(UniProtKB)

IEA

GO:0035999

Q5SNW5(UniProtKB)

IEA

GO:0055114

Q5SNW5(UniProtKB)

IEA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控MTHFR基因的相关microRNA：

hsa-miR-103 hsa-miR-16 hsa-miR-423-3p

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
HOMOCYSTINURIA DUE TO DEFICIENCY OF N(5,10)-METHYLENETETRAHYDROFOLATE REDUCTASE ACTIVITY	0.362171535	11	44	BeFree_CLINVAR_ORPHANET_UNIPROT
Hyperhomocysteinemia	0.337316502	368	22	BeFree_CTD_human_GAD_LHGDN
Cerebrovascular accident	0.257121971	139	7	BeFree_CTD_human_GAD_LHGDN
Cardiovascular Diseases	0.244595919	116	4	BeFree_CTD_human_GAD_LHGDN
Down Syndrome	0.239186945	59	8	BeFree_CTD_human_GAD_LHGDN
Coronary heart disease	0.238855914	126	8	BeFree_CTD_human_GAD_LHGDN
Precursor Cell Lymphoblastic Leukemia Lymphoma	0.232099662	79	7	BeFree_CTD_human_GAD_LHGDN
Stomach Neoplasms	0.225984318	38	0	BeFree_CTD_human_GAD_LHGDN
Neural Tube Defects	0.221794802	41	0	CTD_human_GAD_LHGDN
Schizophrenia	0.218796007	61	4	BeFree_CTD_human_GAD_LHGDN
Thrombophilia	0.216296444	126	1	BeFree_CTD_human_GAD_LHGDN
Venous Thrombosis	0.208173051	49	0	CTD_human_GAD_LHGDN
Rheumatoid Arthritis	0.20430773	49	8	BeFree_CTD_human_GAD_LHGDN
Colorectal Neoplasms	0.203028635	40	0	BeFree_CTD_human_GAD_LHGDN
Brain Ischemia	0.200836406	35	0	CTD_human_GAD_LHGDN
Neural tube defect, folate-sensitive	0.2	0	0	CTD_human_MGD
Alzheimer's Disease	0.189620074	35	4	BeFree_CTD_human_GAD_LHGDN
Cleft Lip	0.181419398	26	0	BeFree_CTD_human_GAD_LHGDN
Congenital Heart Defects	0.167849848	29	1	BeFree_CTD_human_GAD_LHGDN
Colonic Neoplasms	0.162754584	18	1	BeFree_CTD_human_GAD_LHGDN
Mammary Neoplasms	0.160507935	16	0	CTD_human_GAD_LHGDN
Vascular Diseases	0.155222768	67	2	BeFree_CTD_human_GAD
Male infertility	0.148446653	27	3	BeFree_CTD_human_GAD_LHGDN
Homocysteinemia	0.146231817	244	22	BeFree_MGD
Lymphoma	0.144189459	14	1	BeFree_CTD_human_GAD_LHGDN
Graft-vs-Host Disease	0.142746374	8	0	BeFree_CTD_human_GAD_LHGDN
Bipolar Disorder	0.140812605	15	3	BeFree_CTD_human_GAD_LHGDN
Pulmonary Embolism	0.140564907	13	0	BeFree_CTD_human_GAD
Hearing Loss, Sudden	0.136926542	6	0	CTD_human_GAD_LHGDN
Lymphoma, Non-Hodgkin	0.136916611	13	1	BeFree_CTD_human_GAD
Uterine Cervical Neoplasm	0.136569224	7	0	CTD_human_GAD
Cervical Intraepithelial Neoplasia	0.135992664	14	0	BeFree_CTD_human_GAD_LHGDN
Prostatic Neoplasms	0.135631465	6	0	CTD_human_GAD_LHGDN
Coronary Artery Disease	0.135211947	114	5	BeFree_GAD_LHGDN
Chronic Lymphocytic Leukemia	0.135102394	7	0	BeFree_CTD_human_GAD_LHGDN
Kidney Diseases	0.135092462	17	3	BeFree_CTD_human_GAD
Lung Neoplasms	0.132907115	5	0	CTD_human_GAD_LHGDN
Bladder Neoplasm	0.132821238	6	5	BeFree_CTD_human_GAD_LHGDN
Hematological Disease	0.132192478	5	0	CTD_human_GAD_LHGDN
Diabetic Angiopathies	0.132106602	7	0	BeFree_CTD_human_GAD
Blood Coagulation Disorders, Inherited	0.13183516	6	0	CTD_human_GAD
Drug-Induced Liver Injury	0.13183516	7	0	CTD_human_GAD
Autistic Disorder	0.130825337	6	1	BeFree_CTD_human_GAD
Liver diseases	0.12973957	5	0	BeFree_CTD_human_GAD
Anencephaly	0.12827274	4	0	BeFree_GAD_LHGDN_ORPHANET
Neutropenia	0.127372538	5	0	BeFree_CTD_human_GAD
Female infertility	0.127101096	4	0	CTD_human_GAD
Thrombocytopenia	0.127101096	3	0	CTD_human_GAD
Systemic arterial pressure	0.127101096	3	1	GAD_GWASCAT
Depressive disorder	0.125971721	23	2	BeFree_CTD_human
Anemia	0.125819831	6	1	BeFree_CTD_human_GAD
Lymphoma, Follicular	0.125819831	5	0	BeFree_CTD_human_GAD
Meningomyelocele	0.125819831	6	1	BeFree_CTD_human_GAD
Sinus Thrombosis, Intracranial	0.12554839	6	0	BeFree_CTD_human_GAD
Malnutrition	0.12554839	5	1	BeFree_CTD_human_GAD
nervous system disorder	0.125005506	4	0	BeFree_CTD_human_GAD
Gastrointestinal Diseases	0.124734064	3	0	CTD_human_GAD
Dermatologic disorders	0.124734064	3	0	CTD_human_GAD
Inflammatory disease of mucous membrane	0.124734064	2	0	CTD_human_GAD
Coronary Restenosis	0.124734064	2	0	CTD_human_GAD
Blood pressure finding	0.124734064	2	1	GAD_GWASCAT
Leukopenia	0.123724241	6	0	BeFree_CTD_human_GAD
Neoplasm Metastasis	0.123452799	6	0	BeFree_CTD_human_GAD
Congenital clubfoot	0.122638474	1	0	BeFree_CTD_human_GAD
Microvascular Angina	0.122638474	1	0	BeFree_CTD_human_GAD
Methylenetetrahydrofolate reductase deficiency	0.122638474	2	0	BeFree_CTD_human_GAD
Atrial Fibrillation	0.122367032	1	1	GAD_GWASCAT
Endometrial Neoplasms	0.122367032	1	0	CTD_human_GAD
Arsenic Poisoning	0.122367032	2	0	CTD_human_GAD
Peripheral Neuropathy	0.120542884	3	1	BeFree_CTD_human
OROFACIAL CLEFT 1	0.120542884	2	1	BeFree_CTD_human
Spinal Cord Diseases	0.120271442	1	0	BeFree_CTD_human
Thyrotoxicosis	0.120271442	1	0	BeFree_CTD_human
Alopecia	0.12	1	0	CTD_human
Drug Eruptions	0.12	1	0	CTD_human
Hypersensitivity	0.12	1	0	CTD_human
Necrosis	0.12	1	0	CTD_human
Adverse reaction to drug	0.12	11	0	CTD_human
Gastrointestinal Stromal Tumors	0.12	0	2	CLINVAR
Leukoencephalopathies	0.12	1	0	CTD_human
Maxillofacial Abnormalities	0.12	1	0	CTD_human
Microsatellite Instability	0.12	1	0	CTD_human
Mthfr Deficiency, Thermolabile Type	0.12	0	2	CLINVAR
Acute kidney injury	0.12	1	0	CTD_human
Hypertensive disease	0.114562501	76	7	BeFree_GAD_LHGDN
Colorectal Cancer	0.106872745	137	16	BeFree_GAD
Malignant neoplasm of breast	0.100901024	94	16	BeFree_GAD
Liver neoplasms	0.096926542	7	0	GAD_LHGDN_RGD
Diabetes Mellitus, Non-Insulin-Dependent	0.093853467	70	8	BeFree_GAD_LHGDN
Thrombosis	0.093621751	51	1	GAD_LHGDN
Hyperthyroidism	0.082367032	2	0	GAD_RGD
Diabetes Mellitus, Experimental	0.08	1	0	RGD
Hypothyroidism	0.08	1	0	RGD
Pre-Eclampsia	0.074449946	29	0	GAD_LHGDN
Myocardial Infarction	0.069205336	45	9	BeFree_GAD_LHGDN
Folic Acid Deficiency	0.063866256	46	1	BeFree_GAD
Kidney Failure, Chronic	0.063333304	30	2	BeFree_GAD_LHGDN
Atherosclerosis	0.059303945	40	0	BeFree_GAD_LHGDN
Malignant neoplasm of lung	0.05676516	36	13	BeFree_GAD
Migraine Disorders	0.054288508	40	7	BeFree_GAD_LHGDN
Adenocarcinoma	0.053689542	21	0	BeFree_GAD_LHGDN
Squamous cell carcinoma	0.050398564	19	0	BeFree_GAD_LHGDN
Thromboembolism	0.048187303	51	2	BeFree_GAD
Cleft Palate	0.048154965	23	0	BeFree_GAD
Abortion, Habitual	0.047697958	20	0	GAD_LHGDN
leukemia	0.047207275	24	2	BeFree_GAD_LHGDN
Coronary Arteriosclerosis	0.046471437	91	5	BeFree_GAD
Adenoma	0.045369314	19	0	BeFree_GAD_LHGDN
Spina Bifida	0.044558869	32	2	BeFree_GAD_LHGDN
Diabetic Nephropathy	0.041711086	26	2	BeFree_GAD_LHGDN
Malignant neoplasm of esophagus	0.041672698	26	2	BeFree_GAD
Spontaneous abortion	0.037649389	14	0	GAD_LHGDN
Malignant neoplasm of stomach	0.036428088	53	3	BeFree_GAD
Pregnancy loss	0.03550548	15	0	GAD
Venous Thromboembolism	0.033495766	14	0	GAD_LHGDN
Retinal Vein Occlusion	0.033214393	20	1	BeFree_GAD
Esophageal Neoplasms	0.032647765	24	2	BeFree_GAD_LHGDN
Malignant neoplasm of urinary bladder	0.032476012	20	3	BeFree_GAD
Abruptio Placentae	0.031843371	10	0	GAD_LHGDN
Pregnancy Complications	0.031747563	19	2	BeFree_GAD_LHGDN
Leukemia, Lymphocytic, Acute, L1	0.030532311	38	2	BeFree_GAD
Malignant neoplasm of prostate	0.03010898	19	3	BeFree_GAD
Liver carcinoma	0.029823725	12	1	BeFree_GAD_LHGDN
Parkinson Disease	0.029661904	13	1	BeFree_GAD_LHGDN
Obesity	0.029294654	18	2	BeFree_GAD
Ischemic stroke	0.02920744	67	6	BeFree_GAD
Postoperative Complications	0.028404384	12	0	GAD
Pregnancy Complications, Hematologic	0.028404384	12	0	GAD
Colorectal Carcinoma	0.026329862	97	14	BeFree
Activated Protein C Resistance	0.025841855	18	1	BeFree_GAD
Glaucoma, Open-Angle	0.025828042	11	1	BeFree_GAD_LHGDN
Liver Cirrhosis	0.025742166	11	0	BeFree_GAD_LHGDN
Arteriosclerosis	0.025722303	31	0	BeFree_GAD
Anemia, Sickle Cell	0.025103474	19	1	BeFree_GAD
Polycystic Ovary Syndrome	0.024732343	12	0	BeFree_GAD_LHGDN
Cerebrovascular Disorders	0.02367032	10	0	GAD
Myocardial Ischemia	0.023203381	15	0	BeFree_GAD
Peripheral Vascular Diseases	0.023103692	9	0	BeFree_GAD_LHGDN
Epilepsy	0.022636753	14	2	BeFree_GAD_LHGDN
Osteoporosis	0.022365311	14	2	BeFree_GAD_LHGDN
Premature Birth	0.021660606	9	0	GAD_LHGDN
DNA Damage	0.021303288	9	0	GAD
Myeloid Leukemia, Chronic	0.021084047	16	1	BeFree_GAD_LHGDN
Multiple Myeloma	0.020922225	10	1	BeFree_GAD_LHGDN
Ulcerative Colitis	0.020650783	10	1	BeFree_GAD_LHGDN
Breast Carcinoma	0.020629582	76	16	BeFree
Aortic Aneurysm, Abdominal	0.020379342	9	0	BeFree_GAD_LHGDN
Alcoholic Intoxication, Chronic	0.020293465	9	0	BeFree_GAD
Rectal Neoplasms	0.020193776	9	0	BeFree_GAD_LHGDN
Mental Depression	0.019902471	24	0	BeFree_GAD
Diabetes Mellitus	0.01953134	22	2	BeFree_GAD_LHGDN
Vitamin B 12 Deficiency	0.018740759	14	0	BeFree_GAD
Factor V Leiden mutation	0.018729489	69	8	BeFree
Deep Vein Thrombosis	0.018621207	28	1	BeFree_GAD
Congenital Abnormality	0.017078432	19	2	BeFree_GAD_LHGDN
Bone necrosis	0.016926542	7	0	GAD_LHGDN
Pancreatic Neoplasm	0.016926542	6	0	GAD_LHGDN
Leukemia, Myelocytic, Acute	0.016731045	12	2	BeFree_GAD_LHGDN
Inflammatory Bowel Diseases	0.016645169	13	1	BeFree_GAD
Fetal Growth Retardation	0.016569224	7	0	GAD
Behcet Syndrome	0.016102285	10	1	BeFree_GAD
Acute lymphocytic leukemia	0.01601507	59	7	BeFree
Metabolic Syndrome X	0.015635346	16	4	BeFree_GAD
Ischemic Cerebrovascular Accident	0.015472187	57	5	BeFree
Diabetes Mellitus, Insulin-Dependent	0.015287959	8	1	BeFree_GAD
Carotid Artery Diseases	0.014916828	5	0	GAD_LHGDN
Diabetic Retinopathy	0.014635455	12	1	BeFree_GAD_LHGDN
beta Thalassemia	0.014473634	7	0	BeFree_GAD
Neoplasm Recurrence, Local	0.014202192	6	0	GAD
Osteoporosis, Postmenopausal	0.014202192	6	0	GAD
Hyperhomocystinemia	0.014202192	6	0	GAD
Migraine with Aura	0.013897074	16	0	BeFree_GAD_LHGDN
Carcinogenesis	0.013843535	51	3	BeFree
Asthma	0.013278246	7	0	BeFree_GAD_LHGDN
Diffuse Large B-Cell Lymphoma	0.013192369	8	6	BeFree_GAD
Stomach Carcinoma	0.01302921	48	3	BeFree
Antiphospholipid Syndrome	0.013006804	8	0	BeFree_GAD_LHGDN
Exfoliation Syndrome	0.013006804	6	0	BeFree_GAD_LHGDN
Cerebral Infarction	0.01272543	14	1	BeFree_GAD
Malignant neoplasm of ovary	0.01272543	13	7	BeFree_GAD
Fatty Liver	0.012106602	6	1	BeFree_GAD
Hyperlipidemia	0.012106602	6	0	BeFree_GAD
Head and Neck Neoplasms	0.01183516	5	0	GAD
Inflammation	0.01183516	5	0	GAD
Mouth Neoplasms	0.01183516	5	0	GAD
Complications of Diabetes Mellitus	0.01183516	5	0	GAD
Methotrexate poisoning	0.01183516	5	0	GAD
Hyperuricemia	0.011811416	6	0	BeFree_GAD_LHGDN
Transient Ischemic Attack	0.011368221	10	1	BeFree_GAD
Lupus Erythematosus, Systemic	0.011368221	9	1	BeFree_GAD
Protein C Deficiency	0.011096779	10	0	BeFree_GAD
Hepatitis C, Chronic	0.010911214	5	0	BeFree_GAD_LHGDN
Multiple Sclerosis	0.010825337	7	2	BeFree_GAD
Protein S Deficiency	0.010825337	8	0	BeFree_GAD
Meningioma	0.010639772	5	0	BeFree_GAD_LHGDN
Hematologic Neoplasms	0.010639772	7	0	BeFree_GAD_LHGDN
Arterial Occlusive Diseases	0.010553895	7	0	BeFree_GAD
Brain Neoplasms	0.01036833	5	0	BeFree_GAD_LHGDN
Blood Coagulation Disorders	0.010282454	7	2	BeFree_GAD
Crohn Disease	0.010282454	7	0	BeFree_GAD
HELLP Syndrome	0.010282454	5	0	BeFree_GAD
Cervix carcinoma	0.010162901	21	7	BeFree_GAD
Lymphoproliferative Disorders	0.010011012	4	0	BeFree_GAD
Optic Neuropathy, Ischemic	0.009825446	3	0	GAD_LHGDN
Chromosome Aberrations	0.009468128	4	0	GAD
Pregnancy Complications, Cardiovascular	0.009468128	4	0	GAD
Prenatal Exposure Delayed Effects	0.009468128	4	0	GAD
Intracranial Thrombosis	0.009468128	4	0	GAD
Chronic ulcerative colitis	0.009468128	4	0	GAD
Azoospermia	0.009001189	9	1	BeFree_GAD
Dementia	0.009001189	9	0	BeFree_GAD
Glioblastoma	0.008630058	3	2	BeFree_GAD_LHGDN
Sensorineural Hearing Loss (disorder)	0.008458305	7	0	BeFree_GAD
Psoriasis	0.008458305	5	0	BeFree_GAD
Left Ventricular Hypertrophy	0.008358616	3	0	BeFree_GAD_LHGDN
Carotid Stenosis	0.00827274	6	0	BeFree_GAD_LHGDN
Huntington Disease	0.00827274	3	2	BeFree_GAD_LHGDN
Glaucoma	0.008186863	6	0	BeFree_GAD
Oligospermia	0.008186863	6	1	BeFree_GAD
B-Cell Lymphomas	0.008087174	4	0	BeFree_GAD_LHGDN
Angle Closure Glaucoma	0.008001298	2	1	BeFree_GAD_LHGDN
Eclampsia	0.007991366	13	0	BeFree_GAD
Ischemia	0.007915422	5	0	BeFree_GAD
Osteosarcoma	0.007729856	2	0	BeFree_GAD_LHGDN
Heart Diseases	0.00764398	5	2	BeFree_GAD
Hemophilia A	0.00764398	4	1	BeFree_GAD
Hypercholesterolemia	0.00764398	5	1	BeFree_GAD
Brain Infarction	0.00764398	4	0	BeFree_GAD
Malignant tumor of colon	0.007524428	20	1	BeFree_GAD
Infection	0.007458414	3	0	GAD_LHGDN
Cerebral Palsy	0.007372538	4	0	BeFree_GAD
Hemolytic-Uremic Syndrome	0.007372538	3	0	BeFree_GAD
Liver Cirrhosis, Alcoholic	0.007372538	3	0	BeFree_GAD
Metabolic Diseases	0.007372538	4	0	BeFree_GAD
Retinal Artery Occlusion	0.007372538	3	0	BeFree_GAD
T-Cell Lymphoma	0.007372538	3	0	BeFree_GAD
Central Nervous System Neoplasms	0.007372538	3	1	BeFree_GAD
Dementia, Vascular	0.007177041	10	0	BeFree_GAD
Drug toxicity	0.007101096	3	0	GAD
Fetal Diseases	0.007101096	3	0	GAD
Gastrointestinal Neoplasms	0.007101096	3	0	GAD
Insulin Resistance	0.007101096	3	0	GAD
Premature Obstetric Labor	0.007101096	3	0	GAD
Skin Neoplasms	0.007101096	3	0	GAD
Age related macular degeneration	0.007101096	3	0	GAD
Papillomavirus Infections	0.007101096	3	0	GAD
Carcinoma of lung	0.007057489	26	13	BeFree
Homocystinuria	0.005819831	6	0	BeFree_GAD
Mental Retardation	0.005819831	5	1	BeFree_GAD
ovarian neoplasm	0.005720142	3	0	BeFree_LHGDN
Malignant tumor of cervix	0.005700279	21	7	BeFree
Hyperglycemia	0.005634266	2	0	BeFree_GAD_LHGDN
Budd-Chiari Syndrome	0.005634266	2	0	BeFree_GAD_LHGDN
Arterial thrombosis	0.005624334	13	0	BeFree_GAD
Celiac Disease	0.00554839	5	1	BeFree_GAD
Glioma	0.00554839	4	0	BeFree_GAD
Hypercholesterolemia, Familial	0.00554839	3	0	BeFree_GAD
Turner Syndrome	0.00554839	4	1	BeFree_GAD
Adenomatous Polyps	0.00554839	4	0	BeFree_GAD
Common Migraine	0.00554839	5	0	BeFree_GAD
Kidney Failure	0.005428837	20	1	BeFree
Chondrosarcoma	0.005362824	1	0	BeFree_GAD_LHGDN
Acute leukemia	0.005352893	11	1	BeFree_GAD
Aneurysm, Dissecting	0.005276948	4	0	BeFree_GAD
Foramen Ovale, Patent	0.005276948	3	0	BeFree_GAD
Lymphoid leukemia	0.005276948	3	0	BeFree_GAD
Trisomy	0.005276948	3	0	BeFree_GAD
Avitaminosis	0.005276948	4	0	BeFree_GAD
Juvenile arthritis	0.005276948	2	0	BeFree_GAD
Colon Carcinoma	0.005157396	19	1	BeFree
Dislocations	0.005091382	1	0	GAD_LHGDN
Atrophic	0.005091382	2	0	GAD_LHGDN
Leukoaraiosis	0.005091382	2	0	GAD_LHGDN
Cerebral Hemorrhage	0.005091382	1	0	GAD_LHGDN
Non-Small Cell Lung Carcinoma	0.005081451	11	1	BeFree_GAD
Intracranial Aneurysm	0.005005506	2	0	BeFree_GAD
Gaucher Disease	0.005005506	3	0	BeFree_GAD
Neoplasms, Second Primary	0.005005506	2	0	BeFree_GAD
Cataract	0.005005506	2	0	BeFree_GAD
Coronary Stenosis	0.005005506	3	0	BeFree_GAD
Carotid Atherosclerosis	0.004810009	9	1	BeFree_GAD
Major Depressive Disorder	0.004810009	10	2	BeFree_GAD
Burkitt Lymphoma	0.004734064	2	0	GAD
Neoplastic Cell Transformation	0.004734064	2	0	GAD
Choline Deficiency	0.004734064	2	0	GAD
Edema	0.004734064	2	0	GAD
Fetal Membranes, Premature Rupture	0.004734064	2	0	GAD
Gastrointestinal Hemorrhage	0.004734064	2	0	GAD
Hyperplasia	0.004734064	2	0	GAD
Immediate hypersensitivity	0.004734064	2	0	GAD
Infertility	0.004734064	2	0	GAD
Laryngeal neoplasm	0.004734064	2	0	GAD
Chronic Obstructive Airway Disease	0.004734064	2	0	GAD
Pharyngeal Neoplasms	0.004734064	2	0	GAD
Placenta Disorders	0.004734064	2	0	GAD
Precancerous Conditions	0.004734064	2	0	GAD
Retinal vascular occlusion	0.004734064	2	0	GAD
Thromboangiitis Obliterans	0.004734064	2	0	GAD
Vitamin B Deficiency	0.004734064	2	0	GAD
Helicobacter Infections	0.004734064	2	0	GAD
Intracranial Hemorrhages	0.004734064	2	0	GAD
Vertebral Artery Dissection	0.004734064	2	0	GAD
Choroidal Neovascularization	0.004734064	2	0	GAD
Chronic progressive chorea	0.004734064	2	0	GAD
Carotid Artery, Internal, Dissection	0.004734064	2	0	GAD
Intracranial Arterial Diseases	0.004734064	2	0	GAD
Pregnancy associated hypertension	0.004734064	2	0	GAD
Adenoma of large intestine	0.00434307	16	1	BeFree
Congenital heart disease	0.004071628	15	1	BeFree
Squamous cell carcinoma of esophagus	0.004071628	15	2	BeFree
Prostate carcinoma	0.004071628	15	3	BeFree
Carcinoma of bladder	0.004071628	15	3	BeFree
Malignant neoplasm of pancreas	0.003995683	6	0	BeFree_GAD
Esophageal carcinoma	0.003800186	14	2	BeFree
Deep vein thrombosis of lower limb	0.003800186	14	0	BeFree
Aortic Aneurysm	0.003724241	6	2	BeFree_GAD
Cancer of Head and Neck	0.003724241	6	1	BeFree_GAD
Renal Insufficiency	0.003724241	6	0	BeFree_GAD
Hepatitis C	0.003538676	3	0	BeFree_LHGDN
Myeloid Leukemia	0.003538676	3	0	BeFree_LHGDN
Ovarian Carcinoma	0.003528744	13	7	BeFree
Erectile dysfunction	0.003452799	4	1	BeFree_GAD
Restenosis	0.003452799	5	0	BeFree_GAD
Overweight	0.003452799	4	2	BeFree_GAD
Infiltrating Cervical Carcinoma	0.003452799	4	0	BeFree_GAD
polyps	0.003267234	3	1	BeFree_LHGDN
5,10-Methylenetetrahydrofolate reductase deficiency	0.003257302	12	1	BeFree
prothrombin gene mutation	0.003257302	12	1	BeFree
Atrial Septal Defects	0.003181358	3	0	BeFree_GAD
Hepatitis B	0.003181358	3	0	BeFree_GAD
Low Tension Glaucoma	0.003181358	4	0	BeFree_GAD
Malignant neoplasm of liver	0.003181358	4	3	BeFree_GAD
Takayasu Arteritis	0.002995792	1	0	BeFree_LHGDN
Pancreatitis, Chronic	0.002995792	2	0	BeFree_LHGDN
Lateral Sinus Thrombosis	0.002995792	1	0	BeFree_LHGDN
Sarcoma	0.002995792	1	0	BeFree_LHGDN
Rectal Carcinoma	0.002985861	11	1	BeFree
Diabetes	0.002985861	11	2	BeFree
Essential Hypertension	0.002985861	11	1	BeFree
Impaired cognition	0.002985861	11	3	BeFree
early pregnancy	0.002985861	11	1	BeFree
Prothrombin G20210A mutation	0.002985861	11	1	BeFree
alpha-Thalassemia	0.002909916	3	0	BeFree_GAD
Cooley's anemia	0.002909916	2	0	BeFree_GAD
Bronchopulmonary Dysplasia	0.002909916	3	0	BeFree_GAD
Patent ductus arteriosus	0.002909916	2	1	BeFree_GAD
Hodgkin Disease	0.002909916	3	0	BeFree_GAD
Nephroblastoma	0.002909916	2	4	BeFree_GAD
Retinoblastoma	0.002909916	2	5	BeFree_GAD
Seizures	0.002909916	3	0	BeFree_GAD
Stomatitis	0.002909916	3	0	BeFree_GAD
Spina Bifida Occulta	0.002909916	2	0	BeFree_GAD
Bacterial Vaginosis	0.002909916	2	0	BeFree_GAD
Antithrombin III Deficiency	0.002909916	3	0	BeFree_GAD
Conventional (Clear Cell) Renal Cell Carcinoma	0.002909916	2	1	BeFree_GAD
Cardiac defects	0.002909916	3	0	BeFree_GAD
Congenital omphalocele	0.002909916	2	2	BeFree_GAD
Acute Coronary Syndrome	0.002909916	3	0	BeFree_GAD
Arthritis	0.00272435	1	0	LHGDN
Encephalomalacia	0.00272435	1	0	LHGDN
Infarction	0.00272435	1	0	LHGDN
Intellectual Disability	0.00272435	1	0	LHGDN
Unipolar Depression	0.002714419	10	2	BeFree
Acute myocardial infarction	0.002714419	10	3	BeFree
Adult Acute Lymphocytic Leukemia	0.002714419	10	1	BeFree
Cleft Lip with or without Cleft Palate	0.002714419	10	3	BeFree
Endothelial dysfunction	0.002714419	10	3	BeFree
Amyotrophic Lateral Sclerosis	0.002638474	2	0	BeFree_GAD
Aortic Valve Stenosis	0.002638474	2	0	BeFree_GAD
Arthritis, Psoriatic	0.002638474	1	0	BeFree_GAD
Bone Marrow Diseases	0.002638474	2	0	BeFree_GAD
Carcinoma, Transitional Cell	0.002638474	2	0	BeFree_GAD
Diabetic Neuropathies	0.002638474	2	0	BeFree_GAD
Diarrhea	0.002638474	2	0	BeFree_GAD
Gastritis, Atrophic	0.002638474	2	0	BeFree_GAD
Focal glomerulosclerosis	0.002638474	1	0	BeFree_GAD
Graves Disease	0.002638474	1	0	BeFree_GAD
Hepatitis, Chronic	0.002638474	2	0	BeFree_GAD
Pulmonary Hypertension	0.002638474	2	0	BeFree_GAD
Intermittent Claudication	0.002638474	1	0	BeFree_GAD
Legg-Calve-Perthes Disease	0.002638474	2	0	BeFree_GAD
Marfan Syndrome	0.002638474	1	0	BeFree_GAD
Nausea	0.002638474	2	0	BeFree_GAD
Pregnancy in Diabetics	0.002638474	1	0	BeFree_GAD
Henoch-Schoenlein Purpura	0.002638474	2	0	BeFree_GAD
Riboflavin Deficiency	0.002638474	2	0	BeFree_GAD
Systemic Scleroderma	0.002638474	1	0	BeFree_GAD
Varicosity	0.002638474	2	0	BeFree_GAD
von Willebrand Disease	0.002638474	1	0	BeFree_GAD
Cerebral Thrombosis	0.002638474	1	0	BeFree_GAD
Depressive Syndrome	0.002638474	1	0	BeFree_GAD
Essential Tremor	0.002638474	1	1	BeFree_GAD
Sleep Apnea, Obstructive	0.002638474	1	0	BeFree_GAD
Pulmonary Thromboembolisms	0.002638474	2	0	BeFree_GAD
Alcohol Withdrawal Seizures	0.002638474	1	0	BeFree_GAD
Skin carcinoma	0.002638474	2	0	BeFree_GAD
Optic Atrophy, Hereditary, Leber	0.002638474	1	0	BeFree_GAD
Thrombosis of retinal vein	0.002638474	1	0	BeFree_GAD
Fetus affected by placental transfer of anticonvulsant	0.002638474	2	0	BeFree_GAD
Thrombosis of cerebral veins	0.002442977	9	1	BeFree
Glaucoma, Primary Open Angle	0.002442977	9	1	BeFree
Albuminuria	0.002367032	1	0	GAD
Aneuploidy	0.002367032	1	0	GAD
Anoxia	0.002367032	1	0	GAD
Aortic coarctation	0.002367032	1	0	GAD
Apnea	0.002367032	1	0	GAD
Biliary Tract Neoplasm	0.002367032	1	0	GAD
Blood Platelet Disorders	0.002367032	1	0	GAD
Bone neoplasms	0.002367032	1	0	GAD
Brain Damage, Chronic	0.002367032	1	0	GAD
Brain Diseases	0.002367032	1	0	GAD
Cerebral Arterial Diseases	0.002367032	1	0	GAD
Chorioamnionitis	0.002367032	1	0	GAD
Hemophilia B	0.002367032	1	0	GAD
Chromosome Deletion	0.002367032	1	0	GAD
Connective Tissue Diseases	0.002367032	1	0	GAD
Constipation	0.002367032	1	0	GAD
Deafness	0.002367032	1	0	GAD
Demyelinating Diseases	0.002367032	1	0	GAD
Discrete Subaortic Stenosis	0.002367032	1	0	GAD
Drug Allergy	0.002367032	1	0	GAD
Ehlers-Danlos Syndrome	0.002367032	1	0	GAD
Epistaxis	0.002367032	1	0	GAD
Escherichia coli Infections	0.002367032	1	0	GAD
Esophageal and Gastric Varices	0.002367032	1	0	GAD
Femur Head Necrosis	0.002367032	1	0	GAD
Fetal Death	0.002367032	1	0	GAD
Fibrosis	0.002367032	1	0	GAD
Pathological fracture	0.002367032	1	0	GAD
Female Genital Diseases	0.002367032	1	0	GAD
Hearing Loss, Partial	0.002367032	1	0	GAD
Heart Septal Defects	0.002367032	1	0	GAD
Hemorrhage	0.002367032	1	0	GAD
Hepatitis, Toxic	0.002367032	1	0	GAD
HIV Infections	0.002367032	1	0	GAD
Neonatal disorder	0.002367032	1	0	GAD
Kidney Neoplasm	0.002367032	1	0	GAD
Lead Poisoning	0.002367032	1	1	GAD
Leukemia, Lymphocytic, Acute, L2	0.002367032	1	0	GAD
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	0.002367032	1	0	GAD
Adult T-Cell Lymphoma/Leukemia	0.002367032	1	0	GAD
Alcoholic Liver Diseases	0.002367032	1	0	GAD
Lymphatic Metastasis	0.002367032	1	0	GAD
Malaria, Falciparum	0.002367032	1	0	GAD
Animal Mammary Neoplasms	0.002367032	1	0	GAD
Marijuana Abuse	0.002367032	1	0	GAD
Meningeal Neoplasms	0.002367032	1	0	GAD
Mesenteric Vascular Occlusion	0.002367032	1	0	GAD
Mesothelioma	0.002367032	1	0	GAD
Mouth Abnormalities	0.002367032	1	0	GAD
Muscle hypotonia	0.002367032	1	0	GAD
Muscle Spasticity	0.002367032	1	0	GAD
Musculoskeletal Diseases	0.002367032	1	0	GAD
Myeloproliferative disease	0.002367032	1	0	GAD
Nasopharyngeal Neoplasms	0.002367032	1	0	GAD
Nephrosclerosis	0.002367032	1	0	GAD
Obesity, Morbid	0.002367032	1	0	GAD
Ocular Hypertension	0.002367032	1	0	GAD
Pancreatitis	0.002367032	1	0	GAD
Panuveitis	0.002367032	1	0	GAD
Periodontitis	0.002367032	1	0	GAD
Phenylketonurias	0.002367032	1	0	GAD
Phlebitis	0.002367032	1	0	GAD
Pleural Neoplasms	0.002367032	1	0	GAD
Polycythemia	0.002367032	1	0	GAD
Protein-Energy Malnutrition	0.002367032	1	0	GAD
Proteinuria	0.002367032	1	0	GAD
Psychomotor Disorders	0.002367032	1	0	GAD
Psychoses, Substance-Induced	0.002367032	1	0	GAD
Puerperal Disorders	0.002367032	1	0	GAD
Pulmonary Fibrosis	0.002367032	1	0	GAD
Pulmonary Valve Stenosis	0.002367032	1	0	GAD
Purpura, Thrombotic Thrombocytopenic	0.002367032	1	0	GAD
Renal Artery Obstruction	0.002367032	1	0	GAD
Respiratory Distress Syndrome, Adult	0.002367032	1	0	GAD
Rhinitis, Allergic, Perennial	0.002367032	1	0	GAD
Sex Chromosome Aberrations	0.002367032	1	0	GAD
Septic Shock	0.002367032	1	0	GAD
Splenomegaly	0.002367032	1	0	GAD
Subarachnoid Hemorrhage	0.002367032	1	0	GAD
Substance Withdrawal Syndrome	0.002367032	1	0	GAD
Thrombasthenia	0.002367032	1	0	GAD
Urologic Neoplasms	0.002367032	1	0	GAD
Venous Insufficiency	0.002367032	1	0	GAD
Virilism	0.002367032	1	0	GAD
Weight Gain	0.002367032	1	0	GAD
Bronchial Hyperreactivity	0.002367032	1	0	GAD
Arthritis, Reactive	0.002367032	1	0	GAD
Alcoholic Neuropathy	0.002367032	1	0	GAD
Hypoplastic Left Heart Syndrome	0.002367032	1	0	GAD
Adrenoleukodystrophy	0.002367032	1	0	GAD
Iron deficiency anemia	0.002367032	1	0	GAD
Right Ventricular Hypertrophy	0.002367032	1	0	GAD
Aneurysm, Ruptured	0.002367032	1	0	GAD
Neurotoxicity Syndromes	0.002367032	1	0	GAD
Acute Lung Injury	0.002367032	1	0	GAD
Gonadal Dysgenesis, 45,X	0.002367032	1	0	GAD
Oxidative Stress	0.002367032	1	0	GAD
Disease Progression	0.002367032	1	0	GAD
Multiple Chemical Sensitivity	0.002367032	1	0	GAD
Impotence, Vasculogenic	0.002367032	1	0	GAD
Sepsis	0.002367032	1	0	GAD
Gastroschisis	0.002367032	1	0	GAD
Impaired glucose tolerance	0.002367032	1	0	GAD
Hemifacial Spasm	0.002367032	1	0	GAD
Blind Vision	0.002367032	1	0	GAD
body mass	0.002367032	1	0	GAD
Retinal Neoplasms	0.002367032	1	0	GAD
Hepatopulmonary Syndrome	0.002367032	1	0	GAD
Epithelial ovarian cancer	0.002367032	1	0	GAD
Subarachnoid Hemorrhage, Aneurysmal	0.002367032	1	0	GAD
CADASIL Syndrome	0.002367032	1	0	GAD
Hypoxia-Ischemia, Brain	0.002367032	1	0	GAD
Embryo Loss	0.002367032	1	0	GAD
Genomic Instability	0.002367032	1	0	GAD
Stenosis	0.002367032	1	0	GAD
Gastric Cardia Carcinoma	0.002367032	1	0	GAD
Necrotic changes (finding)	0.002367032	1	0	GAD
hearing impairment	0.002367032	1	0	GAD
ASPIRIN RESISTANCE	0.002367032	1	0	GAD
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	0.002367032	1	0	GAD
Proteinuria Adverse Event	0.002367032	1	0	GAD
Congenital cardiac malformations	0.002367032	1	0	GAD
Weight Gain Adverse Event	0.002367032	1	0	GAD
Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified	0.002367032	1	0	GAD
Recurrent pregnancy loss	0.002367032	1	0	GAD
Deficiency of glucose-6-phosphate dehydrogenase	0.002367032	1	0	GAD
Granulomatosis with polyangiitis	0.002367032	1	0	GAD
Hearing Loss	0.002367032	1	0	GAD
Mental disorders	0.002171535	8	3	BeFree
Lupus anticoagulant disorder	0.002171535	8	1	BeFree
THROMBOPHILIA DUE TO ACTIVATED PROTEIN C RESISTANCE (disorder)	0.002171535	8	1	BeFree
Presenile dementia	0.001900093	7	0	BeFree
Retinal Diseases	0.001900093	7	0	BeFree
Cleft palate with cleft lip	0.001900093	7	0	BeFree
Lip and Oral Cavity Carcinoma	0.001900093	7	1	BeFree
Pancreatic carcinoma	0.001900093	7	0	BeFree
Chronic kidney disease stage 5	0.001900093	7	1	BeFree
Malignant neoplasm of mouth	0.001628651	6	0	BeFree
Congenital defects	0.001628651	6	0	BeFree
Microalbuminuria	0.001628651	6	2	BeFree
Arteriopathic disease	0.001628651	6	0	BeFree
Macroangiopathy	0.001628651	6	0	BeFree
Squamous cell carcinoma of the head and neck	0.001628651	6	2	BeFree
Peripheral Arterial Diseases	0.001628651	6	0	BeFree
Malignant neoplasm of thyroid	0.001357209	5	0	BeFree
Lymphoma, Large-Cell, Follicular	0.001357209	5	1	BeFree
Central retinal vein occlusion	0.001357209	5	0	BeFree
Portal vein thrombosis	0.001357209	5	0	BeFree
Cervical intraepithelial neoplasia grade 2	0.001357209	5	2	BeFree
Non-alcoholic Fatty Liver Disease	0.001357209	5	1	BeFree
Thyroid carcinoma	0.001357209	5	0	BeFree
vascular disease occlusive	0.001357209	5	11	BeFree
Helicobacter pylori infection	0.001357209	5	0	BeFree
Acute GVH disease	0.001357209	5	0	BeFree
Attention deficit hyperactivity disorder	0.001357209	5	4	BeFree
Chronic Kidney Diseases	0.001357209	5	1	BeFree
Thrombophilia, hereditary	0.001357209	5	0	BeFree
Autoimmune Diseases	0.001085767	4	0	BeFree
Deep thrombophlebitis	0.001085767	4	0	BeFree
Adenocarcinoma Of Esophagus	0.001085767	4	1	BeFree
Colorectal cancer metastatic	0.001085767	4	0	BeFree
Childhood Leukemia	0.001085767	4	3	BeFree
Autism Spectrum Disorders	0.001085767	4	0	BeFree
Anemia, Megaloblastic	0.000814326	3	0	BeFree
Malignant neoplasm of skin	0.000814326	3	0	BeFree
Cervical dysplasia	0.000814326	3	0	BeFree
Congenital chromosomal disease	0.000814326	3	0	BeFree
Hepatic Vein Thrombosis	0.000814326	3	0	BeFree
Microangiopathy, Diabetic	0.000814326	3	0	BeFree
Psychotic Disorders	0.000814326	3	0	BeFree
Giant Cell Arteritis	0.000814326	3	2	BeFree
Hearing Loss, Mixed Conductive-Sensorineural	0.000814326	3	0	BeFree
Cholangiocarcinoma	0.000814326	3	0	BeFree
Thrombotic stroke	0.000814326	3	0	BeFree
Mesenteric Venous Thrombosis	0.000814326	3	0	BeFree
Arakawa syndrome 2	0.000814326	3	0	BeFree
Malignant neoplasm of colon stage IV	0.000814326	3	0	BeFree
Liver and Intrahepatic Biliary Tract Carcinoma	0.000814326	3	3	BeFree
Cerebral venous sinus thrombosis	0.000814326	3	0	BeFree
Mood Disorders	0.000814326	3	0	BeFree
Maternal hypertension	0.000814326	3	0	BeFree
Cystathionine beta-Synthase Deficiency Disease	0.000814326	3	0	BeFree
Cerebral Ischemia	0.000814326	3	0	BeFree
Gastric Cardia Adenocarcinoma	0.000814326	3	1	BeFree
Sporadic Breast Carcinoma	0.000814326	3	3	BeFree
CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 5	0.000814326	3	1	BeFree
Methylcobalamin Deficiency, CblG Type	0.000814326	3	0	BeFree
Experimental Organism Basal Cell Carcinoma	0.000814326	3	1	BeFree
Lymphoblastic leukemia in children	0.000814326	3	1	BeFree
Anemia, Hemolytic	0.000542884	2	1	BeFree
Borderline Personality Disorder	0.000542884	2	0	BeFree
Malignant neoplasm of endometrium	0.000542884	2	0	BeFree
Malignant neoplasm of larynx	0.000542884	2	0	BeFree
Renal Cell Carcinoma	0.000542884	2	0	BeFree
Drug habituation	0.000542884	2	6	BeFree
Membranous glomerulonephritis	0.000542884	2	1	BeFree
Cardiac Arrest	0.000542884	2	0	BeFree
Lupus Vulgaris	0.000542884	2	0	BeFree
Lupus Erythematosus, Discoid	0.000542884	2	0	BeFree
Primary malignant neoplasm of liver	0.000542884	2	0	BeFree
Nephrotic Syndrome	0.000542884	2	0	BeFree
Ovarian Diseases	0.000542884	2	1	BeFree
Adenomatous Polyposis Coli	0.000542884	2	0	BeFree
Renal Artery Stenosis	0.000542884	2	2	BeFree
Spina Bifida Cystica	0.000542884	2	0	BeFree
Ankylosing spondylitis	0.000542884	2	0	BeFree
Vitiligo	0.000542884	2	0	BeFree
Precursor cell lymphoblastic lymphoma	0.000542884	2	3	BeFree
Depressive Symptoms	0.000542884	2	0	BeFree
Sicca Syndrome	0.000542884	2	0	BeFree
Small cell carcinoma of lung	0.000542884	2	0	BeFree
Oral Cavity Carcinoma	0.000542884	2	1	BeFree
Disease of capillaries	0.000542884	2	0	BeFree
Fibrosis, Liver	0.000542884	2	0	BeFree
Dyslipidemias	0.000542884	2	0	BeFree
Renal sclerosis with hypertension	0.000542884	2	1	BeFree
Severe hereditary factor VIII deficiency disease	0.000542884	2	0	BeFree
Stage III Colon Cancer	0.000542884	2	0	BeFree
Venous retinal branch occlusion	0.000542884	2	0	BeFree
Nonorganic psychosis	0.000542884	2	0	BeFree
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site	0.000542884	2	0	BeFree
Chronic Kidney Insufficiency	0.000542884	2	1	BeFree
Chronic rejection of renal transplant	0.000542884	2	0	BeFree
Lupus Erythematosus	0.000542884	2	0	BeFree
Primary antiphospholipid syndrome	0.000542884	2	0	BeFree
Endometrial Carcinoma	0.000542884	2	0	BeFree
Secondary malignant neoplasm of liver	0.000542884	2	0	BeFree
Neurodegenerative Disorders	0.000542884	2	0	BeFree
Squamous cell carcinoma of skin	0.000542884	2	0	BeFree
Hemophilia, NOS	0.000542884	2	1	BeFree
Secondary malignant neoplasm of lymph node	0.000542884	2	0	BeFree
cardiac event	0.000542884	2	0	BeFree
Brain Tumor, Primary	0.000542884	2	0	BeFree
Transient Cerebral Ischemia	0.000542884	2	0	BeFree
Mild cognitive disorder	0.000542884	2	2	BeFree
Differentiated Thyroid Gland Carcinoma	0.000542884	2	0	BeFree
alpha^+^ Thalassemia	0.000542884	2	0	BeFree
Vitamin Deficiency	0.000542884	2	0	BeFree
Rectal Tumors	0.000542884	2	0	BeFree
Rash and Dermatitis Adverse Event Associated with Chemoradiation	0.000542884	2	0	BeFree
Oral Mucositis	0.000542884	2	0	BeFree
Glioblastoma Multiforme	0.000542884	2	2	BeFree
Non-Neoplastic Disorder	0.000542884	2	0	BeFree
Meningioma, benign, no ICD-O subtype	0.000542884	2	0	BeFree
Azoospermia, Nonobstructive	0.000542884	2	1	BeFree
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)	0.000542884	2	0	BeFree
Nonarteritic anterior ischemic optic neuropathy (NAION)	0.000542884	2	0	BeFree
Uterine Corpus Cancer	0.000542884	2	0	BeFree
Acquired thrombophilia	0.000542884	2	0	BeFree
Stage III Colon Cancer AJCC v7	0.000542884	2	0	BeFree
Nonalcoholic Steatohepatitis	0.000542884	2	0	BeFree
Juvenile rheumatoid arthritis	0.000542884	2	0	BeFree
Acute pancreatitis	0.000271442	1	0	BeFree
Affective Disorders, Psychotic	0.000271442	1	0	BeFree
Osteoporosis, Age-Related	0.000271442	1	0	BeFree
alcohol use disorder	0.000271442	1	1	BeFree
Anxiety Disorders	0.000271442	1	0	BeFree
Arteriovenous fistula	0.000271442	1	0	BeFree
Female Breast Carcinoma	0.000271442	1	0	BeFree
Cerebral Atherosclerosis	0.000271442	1	0	BeFree
Cervix Diseases	0.000271442	1	0	BeFree
Developmental Disabilities	0.000271442	1	0	BeFree
Cluster Headache	0.000271442	1	1	BeFree
Cytomegalovirus Infections	0.000271442	1	0	BeFree
Senile dementia	0.000271442	1	0	BeFree
Dry Eye Syndromes	0.000271442	1	0	BeFree
Dyspnea	0.000271442	1	0	BeFree
Eczema	0.000271442	1	0	BeFree
Breast Fibrocystic Disease	0.000271442	1	0	BeFree
Fibromyalgia	0.000271442	1	0	BeFree
Primary angle-closure glaucoma	0.000271442	1	0	BeFree
Headache	0.000271442	1	0	BeFree
Hemochromatosis	0.000271442	1	0	BeFree
Hepatitis	0.000271442	1	1	BeFree
Hepatitis A	0.000271442	1	1	BeFree
Malaria	0.000271442	1	0	BeFree
melanoma	0.000271442	1	1	BeFree
Premature Menopause	0.000271442	1	0	BeFree
Moyamoya Disease	0.000271442	1	0	BeFree
Neuroblastoma	0.000271442	1	4	BeFree
Pain	0.000271442	1	0	BeFree
Papilloma	0.000271442	1	0	BeFree
Pneumonia	0.000271442	1	0	BeFree
Quadriplegia	0.000271442	1	0	BeFree
Sickle Cell Trait	0.000271442	1	0	BeFree
Smallpox	0.000271442	1	0	BeFree
Temporomandibular Joint Disorders	0.000271442	1	0	BeFree
Temporomandibular Joint Dysfunction Syndrome	0.000271442	1	0	BeFree
Tonsillitis	0.000271442	1	0	BeFree
Uremia	0.000271442	1	0	BeFree
Varicocele	0.000271442	1	1	BeFree
Wheezing	0.000271442	1	0	BeFree
Ovarian Hyperstimulation Syndrome	0.000271442	1	0	BeFree
Ovarian Failure, Premature	0.000271442	1	0	BeFree
Pyoderma Gangrenosum	0.000271442	1	0	BeFree
Idiopathic Membranous Glomerulonephritis	0.000271442	1	0	BeFree
Complete trisomy 18 syndrome	0.000271442	1	0	BeFree
Recurrent major depressive episodes	0.000271442	1	0	BeFree
Old myocardial infarction	0.000271442	1	0	BeFree
Congenital anomaly of aortic arch	0.000271442	1	0	BeFree
Angelman Syndrome	0.000271442	1	0	BeFree
Diplegia	0.000271442	1	1	BeFree
Lesion of brain	0.000271442	1	1	BeFree
Disorder of vein	0.000271442	1	0	BeFree
Malignant neoplasm of female breast	0.000271442	1	0	BeFree
Bipolar II disorder	0.000271442	1	0	BeFree
Neoplasm, Residual	0.000271442	1	1	BeFree
Carcinoma, Small Cell	0.000271442	1	0	BeFree
Childhood asthma	0.000271442	1	0	BeFree
Xeroderma Pigmentosum, Complementation Group D	0.000271442	1	0	BeFree
Gastric Adenocarcinoma	0.000271442	1	1	BeFree
Non-small cell lung cancer metastatic	0.000271442	1	0	BeFree
Solid tumour	0.000271442	1	0	BeFree
Primary central nervous system lymphoma	0.000271442	1	1	BeFree
Dryness of eye	0.000271442	1	0	BeFree
Anastomosis	0.000271442	1	0	BeFree
Squamous intraepithelial lesion	0.000271442	1	0	BeFree
Non-arteritic ischemic optic neuropathy	0.000271442	1	0	BeFree
Proliferative retinopathy	0.000271442	1	0	BeFree
Lemierre Syndrome	0.000271442	1	0	BeFree
Double inlet left ventricle	0.000271442	1	0	BeFree
Cervical intraepithelial neoplasia grade 1	0.000271442	1	0	BeFree
Diagnosis, Psychiatric	0.000271442	1	0	BeFree
Neuropathy	0.000271442	1	0	BeFree
Pervasive Development Disorder	0.000271442	1	0	BeFree
Palmar-plantar erythrodysesthesia syndrome	0.000271442	1	0	BeFree
Severe depression	0.000271442	1	0	BeFree
Carcinoma of larynx	0.000271442	1	0	BeFree
Leukemogenesis	0.000271442	1	0	BeFree
Emotional problems	0.000271442	1	0	BeFree
Central neuroblastoma	0.000271442	1	4	BeFree
Dissecting aneurysm of the thoracic aorta	0.000271442	1	0	BeFree
Subfertility	0.000271442	1	0	BeFree
End Stage Liver Disease	0.000271442	1	0	BeFree
Anterior Ischemic Optic Neuropathy	0.000271442	1	0	BeFree
Sickle Cell Dactylitis	0.000271442	1	0	BeFree
Myelosuppression	0.000271442	1	0	BeFree
Psychotic symptom	0.000271442	1	0	BeFree
Skin toxicity	0.000271442	1	1	BeFree
Hereditary Nonpolyposis Colorectal Cancer	0.000271442	1	1	BeFree
Avascular necrosis of the capital femoral epiphysis	0.000271442	1	0	BeFree
Severe diarrhea	0.000271442	1	0	BeFree
Cirrhosis	0.000271442	1	0	BeFree
Nephrotic Syndrome, Minimal Change	0.000271442	1	0	BeFree
Dysmorphism	0.000271442	1	0	BeFree
Fast acetylator due to N-acetyltransferase enzyme variant	0.000271442	1	0	BeFree
TIBIAL MUSCULAR DYSTROPHY, TARDIVE	0.000271442	1	0	BeFree
malignant neoplasm of large intestine stage IV	0.000271442	1	0	BeFree
Infarction of spinal cord	0.000271442	1	0	BeFree
Steatohepatitis	0.000271442	1	1	BeFree
Moyamoya disease 1	0.000271442	1	0	BeFree
Nasopharyngeal carcinoma	0.000271442	1	0	BeFree
Severe dementia	0.000271442	1	0	BeFree
Hypertensive end stage renal disease	0.000271442	1	0	BeFree
Allergic disposition	0.000271442	1	0	BeFree
Allergic sensitization	0.000271442	1	0	BeFree
Pneumonitis	0.000271442	1	0	BeFree