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Cellular senescence, the terminal nondividing state that normal cells enter following completion of their proliferative potential, is the dominant phenotype in hybrids of normal and immortal cells. Fusions of immortal human cell lines with each other have led to their assignment to 1 of several complementation groups. MORF4 is a gene on chromosome 4 that induces a senescent-like phenotype in cell lines assigned to complementation group B.[supplied by OMIM, Apr 2004]
[中文简述(自动翻译):]  细胞衰老,终端不分裂状态正常细胞输入以下的增殖潜能后,在正常和不朽细胞杂种的主要表型。彼此永生化人细胞系的融合已导致其分配到1几个互补组。 MORF4是在4号染色体的基因诱导衰老一个样表型分配给互补组B. [由OMIM,2004年四月供应]细胞系
MORF4基因(以及对应的蛋白质)的细胞分布位置:
MORF4基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 1 | 0.000542884 | 2 | 0 | BeFree |
Cerebellar Ataxia | 0.000271442 | 1 | 0 | BeFree |
Waldenstrom Macroglobulinemia | 0.000271442 | 1 | 0 | BeFree |
Neoplasm Metastasis | 0.000271442 | 1 | 0 | BeFree |
Tumor Progression | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
Mammary Neoplasms | 0.000271442 | 1 | 0 | BeFree |
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