更多...
收起
Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  真核molybdoenzymes使用唯一的钼辅因子(莫科)由蝶呤的,称为molybdopterin和催化活性金属钼。莫科是由前体?由异源二聚体酶molybdopterin合成酶合成。 molybdopterin合酶的大,小亚单位都从该基因通过重叠的开放阅读框编码。该蛋白质最初被认为是从双顺反子转录物编码。他们现在认为从单顺反子成绩单编码。可变剪接转录物已经被发现对于该位点编码的大,小亚单位。 [由RefSeq的,2008年7月提供]
MOCS2基因(以及对应的蛋白质)的细胞分布位置:
MOCS2基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Molybdenum Cofactor Deficiency, Complementation Group B | 0.36 | 2 | 9 | CLINVAR_ORPHANET_UNIPROT |
| Combined molybdoflavoprotein enzyme deficiency | 0.120271442 | 1 | 0 | BeFree_CTD_human |
| Adenocarcinoma of lung (disorder) | 0.000271442 | 1 | 0 | BeFree |
忘记密码? 点击找回密码.
扫一扫右方二维码,关注微信订阅号,实时查看信息,关注医学生物学动态。