MMP1(matrix metallopeptidase 1)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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11q22.2
基因染色体位置图

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

[中文简述(自动翻译):]  基质金属蛋白酶(MMP)家族的蛋白质是参与细胞外基质的在正常生理过程,诸如胚胎发育,生殖和组织重塑,以及在疾病过程,如关节炎和转移的击穿。大多数的MMP的分泌为当由胞外蛋白酶裂解其中被激活无活性原蛋白。该基因编码一种分解插页胶原,I型,II和III分泌的酶。该基因是定位于染色体11q22.3基质金属蛋白酶的基因簇的一部分。选择性剪接结果在多个抄本变形。[由RefSeq的,2009年03月提供]

MMP1基因的碱基序列:[NCBI]
MMP1基因的碱基突变:           显示全部snp
rs5854       rs10488       rs470132       rs470146       rs470211       rs470215       rs470221       rs470358       rs470558       rs470747       rs473509       rs475007       rs488178       rs491152       rs494379       rs498186       rs513964       rs514921       rs554499       rs657043       rs996999       rs1051121       rs1144391       rs1144393       rs1799750       rs1938901       rs2071230       rs2071231       rs2071232       rs2075847       rs2239008       rs3213460       rs5031035       rs5031036       rs5031037       rs5031038       rs5794198      
rs7124068       rs7125062       rs7125320       rs7945189       rs7951192       rs11225423       rs11225424       rs11225425       rs11225426       rs11557268       rs12272274       rs12274737       rs12276217       rs12282811       rs12417847       rs17099570       rs17293823       rs17878905       rs17878931       rs17879165       rs17879749       rs17879793       rs17879947       rs17879960       rs17879973       rs17880109       rs17880115       rs17880320       rs17880344       rs17880516       rs17880535       rs17880645       rs17880681       rs17881028       rs17881127       rs17881293       rs17881394       rs17882592       rs17882679       rs17882811       rs17882844       rs17882870       rs17883075       rs17883091       rs17883104       rs17883114       rs17883326       rs17883332       rs17883374       rs17883560       rs17883832       rs17883892       rs17883905       rs17883958       rs17884110       rs17884120       rs17884145       rs17884166       rs17884181       rs17885361       rs17885441       rs17885504       rs17885595       rs17885950       rs41372749       rs41500345       rs41524845       rs55707224       rs55855609       rs56028730       rs56142712       rs59142365       rs61753766       rs72979519       rs73589547       rs74367327       rs74951505       rs75938401       rs78362801       rs111469912       rs111822238       rs112444887       rs112855210       rs112916441       rs113840692       rs114064748       rs115234333       rs117105447       rs117217311       rs117245243       rs138320889       rs138753363       rs138965992       rs139018071       rs139040854       rs139305393       rs139520205       rs139639462       rs139997467       rs140490316       rs140947143       rs141392515       rs141429213       rs141541015       rs141648785       rs141726738       rs141894365       rs142553855       rs142693123       rs142727014       rs143028352       rs143369245       rs143788145       rs144260300       rs144302386       rs144507775       rs144780150       rs145093384       rs146230435       rs146320196       rs146623880       rs146815454       rs146827707       rs146887036       rs147115101       rs147162223       rs147429731       rs147712489       rs148103425       rs148343310       rs148660930       rs148980271       rs149206804       rs149392574       rs149654066       rs149950482       rs150261762       rs150423527       rs150583757       rs151023566       rs151325265       rs180887597       rs181297290       rs181317221       rs181629882       rs181901693       rs182813129       rs182968502       rs183066215       rs183080845       rs183499653       rs183704439       rs184045382       rs184380859       rs184731679       rs184756874       rs184942653       rs185030823       rs185093678       rs185519080       rs185737138       rs186155040       rs186237230       rs186352273       rs186592429       rs186779895       rs186925812       rs187196127       rs187781332       rs188019670       rs188622026       rs188631338       rs188826017       rs189318548       rs189449210       rs189545449       rs189548101       rs189889879       rs189918335       rs190047715       rs190146278       rs190817222       rs191292792       rs191441159       rs191669096       rs191778093       rs191933362       rs192223283       rs193049188       rs199702254       rs199890858       rs199921381       rs199962539       rs200033056       rs200225109       rs200225512       rs200481398       rs200717007       rs200717412       rs200783105       rs200810479       rs200875962       rs200901474       rs200931880       rs201210902       rs201622381       rs201865180       rs202131236       rs367819210       rs368239537       rs368255929       rs368596887       rs368681785       rs368784235       rs369054402       rs369603830       rs369607510       rs369683438       rs369712925       rs369847221       rs370309533       rs370349646       rs370666777       rs370904125       rs370930997       rs371023437       rs371046860       rs371106856       rs371416460       rs371427006       rs371484770       rs371763181       rs372011429       rs372513685       rs373218329       rs373263411       rs373305337       rs373359360       rs373359556       rs373810419       rs373917418       rs374046982       rs374132187       rs374237181       rs374301614       rs374421543       rs374600625       rs374616610       rs375290235       rs375378659       rs375460970       rs375492666       rs375609549       rs375910425       rs375963833       rs376000351       rs376573828       rs376619153       rs376694849       rs376794554       rs377007368       rs377717830       rs398017362       rs527647848       rs527810604       rs528475779       rs528498583       rs528509173       rs529202845       rs529240192       rs529296699       rs529604764       rs530019058       rs530266635       rs531079500       rs531195648       rs531235074       rs531240340       rs531312131       rs531857963       rs531860435       rs532310517       rs532629003       rs532716456       rs533183930       rs533795379       rs533950507       rs534153755       rs534208150       rs534230569       rs534244093       rs534862984       rs535183894       rs535674124       rs535760518       rs536303026       rs536532514       rs537241698       rs537600379       rs537761564       rs538195322       rs538356871       rs538746921       rs538772496       rs538940445       rs539285150       rs539611042       rs539851535       rs540479906       rs540640569       rs540800130       rs540946284       rs540992716       rs541029375       rs541510762       rs542431373       rs542694581       rs542710164       rs542812962       rs543411542       rs543487493       rs543607513       rs543821097       rs544569283       rs544664988       rs544791958       rs544830834       rs544847364       rs545342656       rs546697209       rs547280491       rs547554110       rs547794642       rs548077291       rs549366165       rs549443041       rs549574776       rs549736953       rs549772298       rs549774242       rs550059670       rs551375150       rs551646094       rs551718814       rs551757949       rs551852746       rs551951034       rs552005288       rs552936700       rs552982947       rs553425136       rs553879749       rs554158963       rs554275556       rs554434088       rs554474556       rs554476263       rs554687805       rs555261006       rs555545291       rs556086714       rs556437863       rs556473069       rs556475113       rs557019916       rs557251085       rs557555796       rs557912258       rs558564701       rs558605360       rs559014834       rs559414741       rs559745523       rs560145844       rs560647692       rs561438318       rs561475887       rs561524229       rs561545626       rs561613950       rs561973251       rs562126991       rs562565947       rs563454605       rs563532388       rs563603971       rs563609495       rs563681735       rs564127110       rs564177801       rs564251183       rs564384972       rs564452812       rs564661411       rs565112137       rs565603534       rs565759825       rs566118849       rs566239415       rs566402311       rs566440754       rs567324448       rs567735411       rs567970317       rs568278536       rs568306244       rs568578652       rs568606731       rs568780506       rs568818102       rs569381439       rs569968889       rs570282864       rs570743461       rs570784752       rs570972933       rs571363149       rs571818932       rs571957959       rs572072584       rs572860769       rs572987956       rs573101937       rs573819867       rs573869597       rs573952372       rs574269286       rs574861369       rs575091503       rs575419559       rs575573103       rs575688157       rs575699654       rs575976280       rs577398017       rs577562243       rs577676008       rs577707205       rs577747870       rs745361439       rs745447214       rs745459828       rs745486643       rs745629540       rs745680827       rs745944992       rs746033905       rs746223438       rs746276822       rs746320100       rs746410573       rs746470524       rs746603387       rs746799946       rs746853008       rs746899284       rs747080313       rs747168649       rs747191165       rs747355013       rs747359626       rs747482213       rs747509754       rs747609029       rs747957502       rs747966383       rs747995693       rs748195475       rs748231369       rs748413069       rs748514864       rs748601963       rs748656893       rs748779591       rs748873401       rs749127522       rs749381658       rs749490094       rs749612523       rs749621865       rs749745165       rs749936083       rs749945286       rs749993257       rs750031506       rs750068778       rs750253156       rs750325230       rs750376222       rs750555663       rs750559501       rs750677561       rs750788473       rs750832416       rs750841955       rs751094664       rs751235903       rs751266851       rs751399645       rs751464008       rs751676679       rs751705834       rs752018398       rs752020420       rs752027803       rs752249165       rs752344588       rs752475174       rs752655271       rs752781932       rs752871817       rs753130493       rs753164947       rs753339520       rs753536505       rs753617940       rs753618330       rs753853224       rs753967860       rs754040106       rs754126247       rs754278439       rs754500530       rs754506439       rs754773987       rs754821369       rs754850723       rs754987134       rs755062018       rs755263146       rs755320272       rs755536131       rs755565594       rs755568727       rs755624057       rs755625810       rs756000116       rs756073057       rs756183654       rs756183790       rs756242331       rs756276900       rs756459094       rs756497834       rs756674911       rs756698352       rs756742579       rs756797714       rs756802982       rs756925599       rs757057629       rs757086416       rs757211431       rs757252978       rs757344593       rs757515221       rs757705160       rs757824544       rs757959653       rs758013768       rs758158679       rs758228668       rs758390084       rs758415379       rs758426948       rs758477901       rs758666283       rs758719707       rs759012749       rs759085492       rs759136402       rs759244747       rs759301506       rs759317283       rs759332588       rs759699354       rs759862487       rs759913929       rs760055891       rs760093606       rs760204331       rs760288779       rs760385586       rs760477914       rs760499752       rs760636280       rs761000947       rs761045823       rs761052034       rs761086000       rs761145121       rs761280098       rs761545650       rs761955087       rs761972601       rs762006507       rs762171217       rs762231631       rs762246213       rs762436328       rs762524444       rs762620524       rs762758502       rs762758510       rs763002658       rs763024162       rs763139044       rs763277686       rs763336386       rs763359394       rs763404221       rs763452112       rs763706582       rs763713996       rs763801001       rs764055579       rs764134020       rs764434087       rs764594689       rs764831079       rs764946586       rs765184799       rs765368406       rs765414728       rs765465983       rs765496330       rs765547386       rs765703758       rs765760460       rs766154982       rs766351335       rs766420572       rs766426065       rs766495403       rs766610424       rs766661356       rs766891460       rs767057350       rs767092113       rs767123906       rs767270217       rs767373628       rs767391654       rs767825796       rs767873628       rs768059232       rs768064078       rs768066578       rs768176596       rs768524988       rs768578114       rs768701158       rs768912912       rs769027066       rs769079996       rs769243250       rs769298648       rs769474098       rs769719277       rs769954966       rs769965178       rs770146117       rs770402380       rs770408005       rs770439399       rs770633699       rs770681379       rs770721544       rs770946491       rs770947121       rs771043551       rs771377044       rs771568745       rs771608192       rs771718343       rs771828231       rs771914327       rs772091045       rs772120963       rs772186606       rs772268854       rs772321761       rs772718883       rs772882739       rs772991224       rs773055632       rs773149802       rs773218223       rs773369133       rs773474756       rs773483749       rs773833177       rs773882522       rs773910646       rs773957569       rs774010438       rs774067822       rs774256163       rs774355290       rs774532968       rs774561814       rs774851595       rs774975570       rs774980255       rs775008278       rs775033329       rs775415202       rs775505104       rs775721047       rs775753400       rs776034423       rs776063507       rs776079286       rs776265025       rs776450770       rs776690231       rs776690385       rs776741750       rs776917086       rs776917984       rs776928756       rs777005404       rs777151118       rs777199890       rs777202292       rs777202958       rs777511998       rs777593187       rs777734643       rs777784065       rs777883805       rs778222889       rs778252160       rs778453886       rs778606641       rs778660009       rs778741260       rs778791580       rs778882706       rs779024525       rs779266663       rs779423264       rs779509877       rs779778495       rs779824990       rs779961189       rs780014602       rs780053590       rs780055797       rs780246814       rs780986631       rs781072366       rs781074458       rs781173831       rs781180646       rs781292343       rs781307222       rs781620692       rs781660659       rs781662103       rs781662216       rs781697259       rs376000351       rs529240192       rs530266635       rs538746921       rs551757949       rs570972933      

MMP1基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ACAGTAAGCTAACCTTTGATGC
59
TTGTGCGCATGTAGAATCTG
59
CAGTAAGCTAACCTTTGATGCT
59
TTTGTGCGCATGTAGAATCTG
60
CCTCTGACATTCACCAAGGT
60
AGAGTTGTCCCGATGATCTC
59
      尚未收录相关数据

MMP1基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

MMP1基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0004175
P03956(UniProtKB)
IDA
GO:0004222
P03956(UniProtKB)
IDA
GO:0004222
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0004252
P03956(UniProtKB)
TAS
GO:0005509
P03956(UniProtKB)
IEA
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005576
P03956(UniProtKB)
TAS
GO:0005578
P03956(UniProtKB)
IEA
GO:0006508
P03956(UniProtKB)
IDA
GO:0006508
P03956(UniProtKB)
IDA
GO:0008270
P03956(UniProtKB)
IEA
GO:0016032
P03956(UniProtKB)
IEA
GO:0022617
P03956(UniProtKB)
TAS
GO:0030574
P03956(UniProtKB)
TAS
GO:0032461
P03956(UniProtKB)
IDA
GO:0044267
P03956(UniProtKB)
TAS
GO:0050900
P03956(UniProtKB)
TAS
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控MMP1基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Chronic Obstructive Airway Disease 0.225384847 16 0 BeFree_CTD_human_GAD_LHGDN_RGD
Neoplasm Metastasis 0.147173982 74 0 BeFree_CTD_human_LHGDN
Colorectal Neoplasms 0.146528866 11 0 CTD_human_GAD_LHGDN
Mammary Neoplasms 0.140970545 15 0 BeFree_CTD_human_LHGDN
Lung Neoplasms 0.135902907 8 0 BeFree_CTD_human_GAD_LHGDN
Atherosclerosis 0.132354299 12 0 BeFree_CTD_human_GAD_LHGDN
Oral Submucous Fibrosis 0.12764398 5 0 BeFree_CTD_human_GAD
Neoplasm Invasiveness 0.125091382 3 0 CTD_human_GAD_LHGDN
Non-Small Cell Lung Carcinoma 0.123181358 4 0 BeFree_CTD_human_GAD
Hallopeau-Siemens Disease 0.121085767 4 0 BeFree_ORPHANET
Aneurysm 0.120542884 2 0 BeFree_CTD_human
Epidermolysis Bullosa Dystrophica 0.120271442 1 0 BeFree_CTD_human
IGA Glomerulonephritis 0.12 1 0 CTD_human
Liver Cirrhosis, Experimental 0.12 1 0 CTD_human
Ocular Hypertension 0.12 1 0 CTD_human
Non-alcoholic Fatty Liver Disease 0.12 1 0 CTD_human
Preterm premature rupture of membranes (disorder) 0.12 0 0 CLINVAR
PULMONARY DISEASE, CHRONIC OBSTRUCTIVE, RATE OF DECLINE OF LUNG FUNCTION IN 0.12 0 0 CLINVAR
Myocardial Infarction 0.103375134 12 0 BeFree_GAD_LHGDN_RGD
Ulcerative Colitis 0.09162585 7 0 BeFree_GAD_LHGDN_RGD
Diabetes Mellitus, Non-Insulin-Dependent 0.083181358 4 0 BeFree_GAD_RGD
Osteoarthritis, Knee 0.082909916 3 1 BeFree_GAD_RGD
Liver Cirrhosis 0.082638474 4 0 BeFree_GAD_RGD
Heart failure 0.080542884 3 0 BeFree_RGD
Pulmonary Fibrosis 0.080542884 3 0 BeFree_RGD
Sepsis 0.080542884 3 0 BeFree_RGD
Tendinopathy 0.080542884 3 0 BeFree_RGD
Intervertebral Disc Degeneration 0.080271442 2 0 BeFree_RGD
Diabetes Mellitus, Experimental 0.08 1 0 RGD
Hyperplasia 0.08 1 0 RGD
Pulmonary Hypertension 0.08 1 0 RGD
Myocardial Reperfusion Injury 0.08 1 0 RGD
Nephrotic Syndrome 0.08 1 0 CTD_mouse
Scoliosis, unspecified 0.08 1 0 RGD
Fetal Hypoxia 0.08 1 0 RGD
Arthritis, Experimental 0.08 3 0 RGD
Malignant neoplasm of lung 0.026927622 17 0 BeFree_GAD
Colorectal Cancer 0.026732125 20 1 BeFree_GAD
Rheumatoid Arthritis 0.025503061 41 0 BeFree_GAD_LHGDN
Squamous cell carcinoma 0.023622831 18 1 BeFree_GAD_LHGDN
Malignant neoplasm of breast 0.023431216 37 0 BeFree_GAD
Chronic Periodontitis 0.023265513 13 0 BeFree_GAD_LHGDN
melanoma 0.017683448 29 1 BeFree_LHGDN
Liver carcinoma 0.014807208 9 0 BeFree_GAD_LHGDN
Periodontitis 0.014549579 15 0 BeFree_GAD
Degenerative polyarthritis 0.01387333 22 0 BeFree_LHGDN
Malignant neoplasm of urinary bladder 0.013463811 9 1 BeFree_GAD
Systemic Scleroderma 0.012244679 17 0 BeFree_LHGDN
Inflammation 0.012192478 5 0 GAD_LHGDN
Endometriosis 0.011811416 7 0 BeFree_GAD_LHGDN
Renal Cell Carcinoma 0.01162585 4 0 BeFree_GAD_LHGDN
Malignant neoplasm of mouth 0.010282454 6 0 BeFree_GAD
Breast Carcinoma 0.009500466 35 0 BeFree
Malignant neoplasm of prostate 0.009272631 8 0 BeFree_GAD
Coronary heart disease 0.008729747 8 0 BeFree_GAD
Malignant neoplasm of ovary 0.008458305 6 0 BeFree_GAD
Prostatic Neoplasms 0.008444493 4 0 BeFree_LHGDN
Idiopathic Pulmonary Fibrosis 0.008358616 3 0 BeFree_GAD_LHGDN
Asthma 0.00827274 4 0 BeFree_GAD_LHGDN
Tuberculosis, Pulmonary 0.008186863 4 0 BeFree_GAD
Cancer of Head and Neck 0.007915422 4 0 BeFree_GAD
Premature Birth 0.007101096 3 0 GAD
Malignant neoplasm of stomach 0.006981544 17 0 BeFree_GAD
Adenocarcinoma 0.006720033 7 0 BeFree_GAD_LHGDN
Coronary Arteriosclerosis 0.006091273 6 0 BeFree_GAD
Hypertensive disease 0.006091273 5 2 BeFree_GAD
Myopia 0.00554839 5 6 BeFree_GAD
Bladder Neoplasm 0.0054487 2 0 LHGDN
Colorectal Carcinoma 0.005428837 20 1 BeFree
Airway Obstruction 0.005362824 1 0 BeFree_GAD_LHGDN
Cardiomyopathy, Dilated 0.005362824 2 0 BeFree_GAD_LHGDN
Hepatitis C, Chronic 0.005276948 4 5 BeFree_GAD
Malignant neoplasm of kidney 0.005276948 4 0 BeFree_GAD
Acute Coronary Syndrome 0.005276948 3 0 BeFree_GAD
Anoxia 0.005091382 2 0 GAD_LHGDN
Connective Tissue Diseases 0.005091382 2 0 GAD_LHGDN
Alzheimer's Disease 0.005005506 2 0 BeFree_GAD
Carotid Stenosis 0.005005506 2 0 BeFree_GAD
Stomach Carcinoma 0.004885954 18 0 BeFree
Fetal Membranes, Premature Rupture 0.004734064 2 0 GAD
Liver neoplasms 0.004734064 2 0 GAD
Mouth Neoplasms 0.004734064 2 0 GAD
Pre-Eclampsia 0.004734064 2 0 GAD
Malignant neoplasm of brain 0.004734064 2 0 GAD
Chondrosarcoma 0.004624443 7 0 BeFree_LHGDN
Adenoma 0.004353001 7 0 BeFree_LHGDN
Pulmonary Emphysema 0.003800186 14 0 BeFree
Tumor Progression 0.003800186 14 0 BeFree
Inflammatory Bowel Diseases 0.003538676 4 0 BeFree_LHGDN
Lymphatic Metastasis 0.003538676 4 0 BeFree_LHGDN
Sarcoma 0.003538676 4 0 BeFree_LHGDN
Arthritis 0.003452799 5 0 BeFree_GAD
Endometrial Carcinoma 0.003452799 4 0 BeFree_GAD
Coronary Artery Disease 0.003452799 5 0 BeFree_GAD
Crohn Disease 0.003267234 3 0 BeFree_LHGDN
Carcinoma of lung 0.003257302 12 0 BeFree
Cardiovascular Diseases 0.003181358 4 0 BeFree_GAD
Varicosity 0.003181358 3 0 BeFree_GAD
Bone Diseases 0.002995792 1 0 BeFree_LHGDN
Lung diseases 0.002995792 2 0 BeFree_LHGDN
Stomach Neoplasms 0.002995792 2 0 BeFree_LHGDN
Pigmented villonodular synovitis 0.002995792 1 0 BeFree_LHGDN
Cholangiocarcinoma 0.002995792 1 0 BeFree_LHGDN
Bronchiectasis 0.002909916 2 0 BeFree_GAD
Hepatitis C 0.002909916 3 0 BeFree_GAD
Periodontal Diseases 0.002909916 3 0 BeFree_GAD
Chordoma 0.00272435 1 0 LHGDN
Cessation of life 0.00272435 1 0 LHGDN
Granuloma 0.00272435 1 0 LHGDN
Diaphragmatic Hernia 0.00272435 1 0 LHGDN
Liver diseases 0.00272435 1 0 LHGDN
Lyme Disease 0.00272435 1 0 LHGDN
Malaria, Cerebral 0.00272435 1 0 LHGDN
Multiple Myeloma 0.00272435 1 0 LHGDN
Localized scleroderma 0.00272435 1 0 LHGDN
Cardiomyopathies 0.00272435 1 0 LHGDN
Cholangitis, Sclerosing 0.002638474 1 0 BeFree_GAD
Epidermolysis Bullosa 0.002638474 1 0 BeFree_GAD
Esophageal Neoplasms 0.002638474 2 0 BeFree_GAD
Kidney Failure, Chronic 0.002638474 2 0 BeFree_GAD
Periodontitis, Juvenile 0.002638474 2 0 BeFree_GAD
Polycystic Ovary Syndrome 0.002638474 1 0 BeFree_GAD
Pruritus 0.002638474 1 0 BeFree_GAD
Dermatologic disorders 0.002638474 2 0 BeFree_GAD
Cerebrovascular accident 0.002638474 2 0 BeFree_GAD
Urinary Stress Incontinence 0.002638474 2 0 BeFree_GAD
alpha 1-Antitrypsin Deficiency 0.002638474 1 0 BeFree_GAD
Conventional (Clear Cell) Renal Cell Carcinoma 0.002638474 1 0 BeFree_GAD
Chronic liver disease 0.002638474 2 0 BeFree_GAD
Metabolic Syndrome X 0.002638474 2 0 BeFree_GAD
Tuberculosis 0.002442977 9 0 BeFree
Carcinogenesis 0.002442977 9 0 BeFree
Alveolar Bone Loss 0.002367032 1 0 GAD
Amyotrophic Lateral Sclerosis 0.002367032 1 0 GAD
Bronchial Diseases 0.002367032 1 0 GAD
Bronchitis 0.002367032 1 0 GAD
Carotid Artery Diseases 0.002367032 1 0 GAD
Chorioamnionitis 0.002367032 1 0 GAD
Coronary Aneurysm 0.002367032 1 0 GAD
Hearing Loss, Sudden 0.002367032 1 0 GAD
Diabetic Angiopathies 0.002367032 1 0 GAD
Eclampsia 0.002367032 1 0 GAD
Pathological accumulation of air in tissues 0.002367032 1 0 GAD
Fetal Diseases 0.002367032 1 0 GAD
Fibrosis 0.002367032 1 0 GAD
Graft Occlusion, Vascular 0.002367032 1 0 GAD
Hay fever 0.002367032 1 0 GAD
Head and Neck Neoplasms 0.002367032 1 0 GAD
Kidney Neoplasm 0.002367032 1 0 GAD
Premature Obstetric Labor 0.002367032 1 0 GAD
Lymphoma, Non-Hodgkin 0.002367032 1 0 GAD
Mitral Valve Insufficiency 0.002367032 1 0 GAD
Mitral Valve Prolapse Syndrome 0.002367032 1 0 GAD
Mucocutaneous Lymph Node Syndrome 0.002367032 1 0 GAD
Multiple Sclerosis 0.002367032 1 0 GAD
Musculoskeletal Diseases 0.002367032 1 0 GAD
Nasopharyngeal Neoplasms 0.002367032 1 0 GAD
Neoplasm Recurrence, Local 0.002367032 1 0 GAD
Parkinson Disease 0.002367032 1 0 GAD
Periodontal Pocket 0.002367032 1 0 GAD
Pneumonia 0.002367032 1 0 GAD
Pregnancy Complications, Hematologic 0.002367032 1 0 GAD
Spinal Diseases 0.002367032 1 0 GAD
Gastric ulcer 0.002367032 1 0 GAD
Thrombosis 0.002367032 1 0 GAD
Tongue Neoplasms 0.002367032 1 0 GAD
Tracheal Stenosis 0.002367032 1 0 GAD
Peripheral Vascular Diseases 0.002367032 1 0 GAD
Left Ventricular Hypertrophy 0.002367032 1 0 GAD
Aortic Aneurysm, Abdominal 0.002367032 1 0 GAD
Periodontal Attachment Loss 0.002367032 1 0 GAD
Lichen Planus, Oral 0.002367032 1 0 GAD
Cancer of Nasopharynx 0.002367032 1 0 GAD
Scleroderma, Limited 0.002367032 1 0 GAD
Carotid Artery, Internal, Dissection 0.002367032 1 0 GAD
Pregnancy associated hypertension 0.002367032 1 0 GAD
HIV-Associated Lipodystrophy Syndrome 0.002367032 1 0 GAD
Diffuse Scleroderma 0.002367032 1 0 GAD
Stenosis 0.002367032 1 0 GAD
Blood pressure finding 0.002367032 1 0 GAD
Systemic arterial pressure 0.002367032 1 0 GAD
Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified 0.002367032 1 0 GAD
Infection 0.002367032 1 0 GAD
Arteriosclerosis 0.002171535 8 0 BeFree
Prostate carcinoma 0.002171535 8 0 BeFree
Secondary malignant neoplasm of lymph node 0.002171535 8 0 BeFree
Ovarian Carcinoma 0.001900093 7 0 BeFree
Fibrosis, Liver 0.001628651 6 5 BeFree
Carcinoma of bladder 0.001628651 6 1 BeFree
Squamous cell carcinoma of the head and neck 0.001628651 6 0 BeFree
Nasopharyngeal carcinoma 0.001628651 6 7 BeFree
Scleroderma 0.001357209 5 0 BeFree
Pancreatic carcinoma 0.001357209 5 0 BeFree
Cervix carcinoma 0.001357209 5 0 BeFree
Colon Carcinoma 0.001357209 5 0 BeFree
Malignant tumor of cervix 0.001085767 4 0 BeFree
Glioblastoma 0.001085767 4 0 BeFree
Glioma 0.001085767 4 0 BeFree
Malignant neoplasm of pancreas 0.001085767 4 0 BeFree
Epithelial ovarian cancer 0.001085767 4 0 BeFree
Diabetes 0.000814326 3 0 BeFree
Diabetes Mellitus 0.000814326 3 0 BeFree
Fibrosarcoma 0.000814326 3 0 BeFree
Fibroid Tumor 0.000814326 3 0 BeFree
Pterygium 0.000814326 3 0 BeFree
Uterine Fibroids 0.000814326 3 0 BeFree
Severe Combined Immunodeficiency 0.000814326 3 0 BeFree
Cutaneous Melanoma 0.000814326 3 0 BeFree
Esophageal carcinoma 0.000814326 3 0 BeFree
Secondary malignant neoplasm of lung 0.000814326 3 0 BeFree
Secondary malignant neoplasm of bone 0.000814326 3 0 BeFree
Acute myocardial infarction 0.000814326 3 0 BeFree
Lip and Oral Cavity Carcinoma 0.000814326 3 0 BeFree
Metastatic malignant neoplasm to brain 0.000814326 3 0 BeFree
Squamous cell carcinoma of esophagus 0.000814326 3 0 BeFree
Adenocarcinoma Of Esophagus 0.000814326 3 0 BeFree
Superficial ulcer 0.000814326 3 0 BeFree
Glaucoma, Primary Open Angle 0.000814326 3 3 BeFree
Invasive breast carcinoma 0.000814326 3 0 BeFree
Pelvic Organ Prolapse 0.000814326 3 0 BeFree
Chronic Kidney Diseases 0.000814326 3 7 BeFree
Invasive Skin Melanoma 0.000814326 3 0 BeFree
Aortic Aneurysm 0.000542884 2 7 BeFree
Malignant tumor of colon 0.000542884 2 0 BeFree
Celiac Disease 0.000542884 2 0 BeFree
Cystic Fibrosis 0.000542884 2 0 BeFree
Dermatitis Herpetiformis 0.000542884 2 0 BeFree
Diverticulitis 0.000542884 2 0 BeFree
Breast Fibrocystic Disease 0.000542884 2 0 BeFree
Gastroesophageal reflux disease 0.000542884 2 0 BeFree
Gingival Diseases 0.000542884 2 0 BeFree
Glaucoma 0.000542884 2 0 BeFree
Congestive heart failure 0.000542884 2 0 BeFree
HIV Infections 0.000542884 2 0 BeFree
Keloid 0.000542884 2 0 BeFree
Meningioma 0.000542884 2 0 BeFree
Nasal Polyps 0.000542884 2 0 BeFree
Obesity 0.000542884 2 0 BeFree
Osteosarcoma 0.000542884 2 0 BeFree
Septicemia 0.000542884 2 0 BeFree
Vascular Diseases 0.000542884 2 0 BeFree
Pancreatitis, Chronic 0.000542884 2 1 BeFree
Adenocarcinoma of lung (disorder) 0.000542884 2 0 BeFree
MERRF Syndrome 0.000542884 2 0 BeFree
Follicular adenoma 0.000542884 2 0 BeFree
Exfoliation Syndrome 0.000542884 2 0 BeFree
Colitis, Collagenous 0.000542884 2 0 BeFree
Laryngeal Squamous Cell Carcinoma 0.000542884 2 0 BeFree
Multiple malignancy 0.000542884 2 0 BeFree
Squamous cell carcinoma of tongue 0.000542884 2 0 BeFree
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site 0.000542884 2 0 BeFree
Hereditary gingival fibromatosis 0.000542884 2 0 BeFree
Thyroid carcinoma 0.000542884 2 0 BeFree
Ewings sarcoma 0.000542884 2 0 BeFree
Malignant Glioma 0.000542884 2 0 BeFree
Carotid Atherosclerosis 0.000542884 2 0 BeFree
Osteosarcoma of bone 0.000542884 2 0 BeFree
Tumor Initiation 0.000542884 2 0 BeFree
Malignant neoplasm of gastrointestinal tract 0.000542884 2 0 BeFree
Helicobacter pylori infection 0.000542884 2 0 BeFree
Intraepithelial Neoplasia 0.000542884 2 0 BeFree
Conjunctivochalasis 0.000542884 2 0 BeFree
Adenoma of large intestine 0.000542884 2 0 BeFree
Renal carcinoma 0.000542884 2 0 BeFree
Xenograft Model 0.000542884 2 0 BeFree
Glioblastoma Multiforme 0.000542884 2 0 BeFree
Arteriovenous fistula 0.000271442 1 0 BeFree
Arthritis, Psoriatic 0.000271442 1 0 BeFree
Astrocytoma 0.000271442 1 0 BeFree
Autoimmune Diseases 0.000271442 1 0 BeFree
Malignant neoplasm of endometrium 0.000271442 1 0 BeFree
Malignant neoplasm of skin 0.000271442 1 0 BeFree
Carcinoma, Transitional Cell 0.000271442 1 0 BeFree
Cerebellar Ataxia 0.000271442 1 0 BeFree
Transient Ischemic Attack 0.000271442 1 0 BeFree
Chlamydia Infections 0.000271442 1 0 BeFree
Contracture 0.000271442 1 0 BeFree
Cutis Laxa 0.000271442 1 0 BeFree
Cyst 0.000271442 1 0 BeFree
Stasis dermatitis 0.000271442 1 0 BeFree
Dermatomyositis 0.000271442 1 0 BeFree
Enteritis 0.000271442 1 0 BeFree
Eosinophilia 0.000271442 1 0 BeFree
Nonproliferative fibrocystic disease 0.000271442 1 0 BeFree
Hepatitis, Chronic 0.000271442 1 0 BeFree
Hernia 0.000271442 1 1 BeFree
Von Hippel-Lindau Syndrome 0.000271442 1 0 BeFree
Hypercholesterolemia, Familial 0.000271442 1 0 BeFree
Immunologic Deficiency Syndromes 0.000271442 1 0 BeFree
Actinic keratosis 0.000271442 1 0 BeFree
Low Back Pain 0.000271442 1 1 BeFree
Lymphoma 0.000271442 1 0 BeFree
Muscular Dystrophy 0.000271442 1 0 BeFree
Neck Neoplasms 0.000271442 1 0 BeFree
Melanocytic nevus 0.000271442 1 0 BeFree
Osteomyelitis 0.000271442 1 0 BeFree
Osteoporosis 0.000271442 1 0 BeFree
Ovarian Cysts 0.000271442 1 0 BeFree
Ovarian Diseases 0.000271442 1 0 BeFree
Pain 0.000271442 1 0 BeFree
Papilloma 0.000271442 1 0 BeFree
Pituitary Adenoma 0.000271442 1 0 BeFree
Pneumothorax 0.000271442 1 0 BeFree
Precancerous Conditions 0.000271442 1 0 BeFree
Respiration Disorders 0.000271442 1 0 BeFree
Respiratory Tract Diseases 0.000271442 1 0 BeFree
Rheumatoid Nodule 0.000271442 1 0 BeFree
Stricture of artery 0.000271442 1 0 BeFree
Erythema 0.000271442 1 0 BeFree
Xeroderma Pigmentosum 0.000271442 1 0 BeFree
Epidermolysis Bullosa Acquisita 0.000271442 1 0 BeFree
Polymyositis 0.000271442 1 0 BeFree
Alcohol abuse 0.000271442 1 0 BeFree
Amaurosis Fugax 0.000271442 1 0 BeFree
Thyroid Gland Follicular Adenoma 0.000271442 1 0 BeFree
Periosteal Disorder 0.000271442 1 0 BeFree
Hemangioma of retina 0.000271442 1 0 BeFree
Old myocardial infarction 0.000271442 1 0 BeFree
Endometriosis of ovary 0.000271442 1 0 BeFree
Mitochondrial Encephalomyopathies 0.000271442 1 0 BeFree
Cicatrix, Hypertrophic 0.000271442 1 0 BeFree
Anaplastic carcinoma 0.000271442 1 0 BeFree
Diabetic Foot 0.000271442 1 0 BeFree
Giant Cell Tumor of Bone 0.000271442 1 0 BeFree
Follicular thyroid carcinoma 0.000271442 1 0 BeFree
Carcinoma, Lobular 0.000271442 1 0 BeFree
Verrucous carcinoma 0.000271442 1 0 BeFree
Hemangioblastoma 0.000271442 1 0 BeFree
Reactive systemic amyloidosis 0.000271442 1 0 BeFree
Adult type dermatomyositis 0.000271442 1 0 BeFree
Trichiasis 0.000271442 1 0 BeFree
Inclusion Body Myositis (disorder) 0.000271442 1 0 BeFree
Light chain disease 0.000271442 1 0 BeFree
Hepatitis, Autoimmune 0.000271442 1 0 BeFree
Lyme Arthritis 0.000271442 1 0 BeFree
Age related macular degeneration 0.000271442 1 0 BeFree
Primary amyloidosis 0.000271442 1 0 BeFree
Severe myopia 0.000271442 1 0 BeFree
Coinfection 0.000271442 1 0 BeFree
Gastric Adenocarcinoma 0.000271442 1 0 BeFree
Metastatic melanoma 0.000271442 1 0 BeFree
Adenocarcinoma of pancreas 0.000271442 1 0 BeFree
Prolapsed lumbar disc 0.000271442 1 0 BeFree
Restenosis 0.000271442 1 0 BeFree
Fibrous bands 0.000271442 1 0 BeFree
Adenocarcinoma of colon 0.000271442 1 0 BeFree
Superior limbic keratoconjunctivitis 0.000271442 1 0 BeFree
Collagenous Sprue 0.000271442 1 0 BeFree
Endometriosis of uterus 0.000271442 1 0 BeFree
Cervical intraepithelial neoplasia grade 1 0.000271442 1 0 BeFree
Isolated aortic stenosis 0.000271442 1 0 BeFree
Progressive pseudorheumatoid dysplasia 0.000271442 1 0 BeFree
Secondary malignant neoplasm of liver 0.000271442 1 0 BeFree
Decreased drug resistance 0.000271442 1 0 BeFree
Malignant neoplasm of esophagus 0.000271442 1 0 BeFree
Primary sclerosing cholangitis 0.000271442 1 0 BeFree
invasive cancer 0.000271442 1 0 BeFree
airway disease 0.000271442 1 0 BeFree
Lymphangioleiomyomatosis 0.000271442 1 0 BeFree
Arteriopathic disease 0.000271442 1 0 BeFree
Muscle fibrosis 0.000271442 1 0 BeFree
ovarian neoplasm 0.000271442 1 0 BeFree
Ischemic stroke 0.000271442 1 0 BeFree
Epidermolysis Bullosa Pruriginosa 0.000271442 1 0 BeFree
Chronic venous insufficiency 0.000271442 1 0 BeFree
Eosinophilic disorder 0.000271442 1 0 BeFree
Peripheral arterial occlusive disease 0.000271442 1 0 BeFree
Adenocarcinoma of large intestine 0.000271442 1 0 BeFree
Hereditary Nonpolyposis Colorectal Cancer 0.000271442 1 0 BeFree
Infiltrating Cervical Carcinoma 0.000271442 1 0 BeFree
Pancreatic Ductal Adenocarcinoma 0.000271442 1 0 BeFree
Epithelioma 0.000271442 1 0 BeFree
Diabetic foot ulcer 0.000271442 1 0 BeFree
Non-ST elevation (NSTEMI) myocardial infarction 0.000271442 1 0 BeFree
Cirrhosis 0.000271442 1 0 BeFree
Disorder characterized by eosinophilia 0.000271442 1 0 BeFree
Direct Contact Transmission Infection 0.000271442 1 0 BeFree
Non-Neoplastic Disorder 0.000271442 1 0 BeFree
Meningioma, benign, no ICD-O subtype 0.000271442 1 0 BeFree
Uterine Corpus Cancer 0.000271442 1 0 BeFree
Trichothiodystrophy Syndromes 0.000271442 1 0 BeFree
Cakut 0.000271442 1 0 BeFree
XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C 0.000271442 1 0 BeFree
aggressive cancer 0.000271442 1 0 BeFree
Nonalcoholic Steatohepatitis 0.000271442 1 0 BeFree
Ischemic Cerebrovascular Accident 0.000271442 1 0 BeFree
Early Hepatocellular Carcinoma 0.000271442 1 0 BeFree
AA amyloidosis 0.000271442 1 0 BeFree
Astrocytoma of brain 0.000271442 1 0 BeFree
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