MIR182基因详情-基因数据库-基因云馆

MIR182(microRNA 182) 转至新版数据库

基因简称(symbol)

MIR182 [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

non-coding RNA

同源简称(alias symbol)

hsa-mir-182

基因家族代码(gene_family_id)

476 [HGNC] [GenScript]

omim代码

611607

entrez码

406958 [Vega]

vega基因码

ensembl基因码

ENSG00000207990 [Ensembl]

基因家族(gene family)

MicroRNAs

refseq数据库代号

NR_029614

更多...

基因种类(locus_type)

RNA, micro

基因名称状态(status)

Approved

location_sortable

07q32.2

同源基因名称(alias name)

基因名称批准使用时间(date_approved_reserved)

2004-04-23T00:00:00Z

基因简称更名时间(date_symbol_changed)

2008-12-18T00:00:00Z

基因名称更名时间(date_name_changed)

更新时间(date_modified)

2011-09-12T00:00:00Z

ucsc码

uc011kpb.1

ena

ccds数据码

uniprot数据码

pubmed代码

mgd码

rgd码

生命科学数据库(lsdb)

更新时间(date modified)

2011-09-12T00:00:00Z

cosmic

mirbase

MI0000272

基因曾用简称(prev symbol)

MIRN182

基因曾用名称(prev name)

homeodb

cosmic

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

7q32.2

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

[中文简述(自动翻译):] 微RNA（miRNAs）是短（20-24核苷酸）非编码由既影响稳定性和mRNA的翻译参与基因表达的转录后调控在多细胞生物体的RNA。的miRNA通过RNA聚合酶II转录为加盖并聚腺苷酸化初级转录物的部分（PRI-微RNA），可以是任一蛋白质编码或非编码。初级转录由酶Drosha核糖核酸酶III酶裂解以产生约70个核苷酸茎 - 环前体miRNA（前miRNA），这是由胞质Dicer的核糖核酸酶进一步切割以产生成熟miRNA和反义miRNA的星（miRNA的* ）产品。成熟miRNA掺入RNA诱导的沉默复合物（RISC），其通过不完全碱基配对识别靶mRNA与所述miRNA和最通常导致翻译抑制或去稳定化的靶mRNA。所述的RefSeq表示预测的微RNA茎环。 [由RefSeq的，2009年09月提供]

OMIM数据库中对MIR182基因的介绍 Wikipedia数据库中对MIR182基因的介绍

MIR182基因的碱基序列：[NCBI]

MIR182基因的碱基突变：显示全部snp

rs4467881 rs4541843 rs7809195 rs17557575 rs75458972 rs75953509 rs76481776 rs77368416 rs77586312 rs80041074 rs117487540 rs118167315 rs137909244 rs138262615 rs140774601 rs146919637 rs147680562 rs182030381 rs186341047 rs188292868 rs190944933 rs191437640 rs370684501 rs370756213 rs372552704 rs374455999 rs377385145 rs527449054 rs531356464 rs531522276 rs538561416 rs539345665 rs539405729 rs542672531 rs543319533 rs544255216 rs549429861

rs550544767 rs551469017 rs551498253 rs555668457 rs556075087 rs560411167 rs560945946 rs561268259 rs562483878 rs562602176 rs566851839 rs566990825 rs568875045 rs568913059 rs569182462 rs572029987 rs573391631 rs577722340 rs745987374 rs747272947 rs747974273 rs749743561 rs753643419 rs753786239 rs756391657 rs758282766 rs760057663 rs760141917 rs760187044 rs760402897 rs763074350 rs763467337 rs764145073 rs764359536 rs765711016 rs765932794 rs766438318 rs767240169 rs769078163 rs769973865 rs770387494 rs774529879 rs775588978 rs776110911 rs776516191 rs777265801 rs777296542 rs777369020 rs778867483 rs781452649 rs11971745 rs11982509 rs111360701 rs112495127 rs113919036 rs114263509 rs142867097 rs146289213 rs149621836 rs184880349 rs187492689 rs192466157 rs532259763 rs532696411 rs534809775 rs535895695 rs536773892 rs538401725 rs538671326 rs539361134 rs540970791 rs541287485 rs541723620 rs542359825 rs543005928 rs543207767 rs547770268 rs547813049 rs549218740 rs550269495 rs550381286 rs552549171 rs553013032 rs553040050 rs553611783 rs554396939 rs554412507 rs554607586 rs556937045 rs558184935 rs559559207 rs560307581 rs561401411 rs564866161 rs571833221 rs574659775 rs575712115 rs576602674 rs576636556

MIR182基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

CAATGGTAGAACTCACACTGG

59

ATAGTTGGCAAGTCTAGAACC

58

AATGGTAGAACTCACACTGG

57

CATAGTTGGCAAGTCTAGAACC

59

GGCAATGGTAGAACTCACAC

59

AGTTGGCAAGTCTAGAACC

57

尚未收录相关数据

MIR182基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

MIR182基因的本体（GO）信息：

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控MIR182基因的相关microRNA：

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
melanoma	0.004353001	6	0	BeFree_LHGDN
Neoplasm Metastasis	0.00434307	16	0	BeFree
Sleep Initiation and Maintenance Disorders	0.002367032	1	0	GAD
Ovarian Carcinoma	0.001900093	7	0	BeFree
Malignant neoplasm of lung	0.001900093	7	0	BeFree
Carcinoma of lung	0.001900093	7	0	BeFree
Malignant neoplasm of ovary	0.001900093	7	0	BeFree
Malignant neoplasm of breast	0.001628651	6	0	BeFree
Colorectal Carcinoma	0.001628651	6	0	BeFree
Carcinogenesis	0.001628651	6	0	BeFree
Breast Carcinoma	0.001628651	6	0	BeFree
Malignant neoplasm of prostate	0.001357209	5	0	BeFree
Prostate carcinoma	0.001357209	5	0	BeFree
Glioma	0.001085767	4	0	BeFree
Malignant neoplasm of stomach	0.001085767	4	0	BeFree
Secondary malignant neoplasm of lymph node	0.001085767	4	0	BeFree
Colorectal Cancer	0.001085767	4	0	BeFree
Liver carcinoma	0.001085767	4	0	BeFree
Malignant tumor of colon	0.000814326	3	0	BeFree
Non-Small Cell Lung Carcinoma	0.000814326	3	0	BeFree
Secondary malignant neoplasm of lung	0.000814326	3	0	BeFree
Colon Carcinoma	0.000814326	3	0	BeFree
Stomach Carcinoma	0.000814326	3	0	BeFree
Sarcoma	0.000814326	3	0	BeFree
Adenocarcinoma	0.000542884	2	0	BeFree
Malignant neoplasm of urinary bladder	0.000542884	2	0	BeFree
Squamous cell carcinoma	0.000542884	2	0	BeFree
Diabetes Mellitus, Non-Insulin-Dependent	0.000542884	2	0	BeFree
Adenocarcinoma of lung (disorder)	0.000542884	2	0	BeFree
Tumor Progression	0.000542884	2	0	BeFree
Uveal melanoma	0.000542884	2	0	BeFree
Metastatic melanoma	0.000542884	2	0	BeFree
Endometrial Carcinoma	0.000542884	2	0	BeFree
Secondary malignant neoplasm of liver	0.000542884	2	0	BeFree
Epithelial ovarian cancer	0.000542884	2	0	BeFree
Carcinoma of bladder	0.000542884	2	0	BeFree
Adenocarcinoma of large intestine	0.000542884	2	0	BeFree
Triple Negative Breast Neoplasms	0.000542884	2	0	BeFree
Adenoma	0.000271442	1	0	BeFree
Mental disorders	0.000271442	1	0	BeFree
Behcet Syndrome	0.000271442	1	0	BeFree
Renal Cell Carcinoma	0.000271442	1	0	BeFree
Malignant tumor of cervix	0.000271442	1	0	BeFree
Colonic Polyps	0.000271442	1	0	BeFree
Mental Depression	0.000271442	1	0	BeFree
Depressive disorder	0.000271442	1	0	BeFree
Diabetes	0.000271442	1	0	BeFree
Diabetes Mellitus	0.000271442	1	0	BeFree
Glioblastoma	0.000271442	1	0	BeFree
Congestive heart failure	0.000271442	1	0	BeFree
Hyperglycemia	0.000271442	1	0	BeFree
Kidney Failure, Acute	0.000271442	1	0	BeFree
Lymphoma	0.000271442	1	0	BeFree
Medulloblastoma	0.000271442	1	0	BeFree
Neuroblastoma	0.000271442	1	0	BeFree
Polycythemia Vera	0.000271442	1	0	BeFree
polyps	0.000271442	1	0	BeFree
Prostatic Neoplasms	0.000271442	1	0	BeFree
Ankylosing spondylitis	0.000271442	1	0	BeFree
Uveomeningoencephalitic Syndrome	0.000271442	1	0	BeFree
Malignant neoplasm of gallbladder	0.000271442	1	0	BeFree
Gallbladder Carcinoma	0.000271442	1	0	BeFree
Multiple tumors	0.000271442	1	0	BeFree
Gastric Adenocarcinoma	0.000271442	1	0	BeFree
Cervix carcinoma	0.000271442	1	0	BeFree
Multiple malignancy	0.000271442	1	0	BeFree
Disseminated Malignant Neoplasm	0.000271442	1	0	BeFree
Splenic Marginal Zone B-Cell Lymphoma	0.000271442	1	0	BeFree
Malignant Glioma	0.000271442	1	0	BeFree
Late insomnia	0.000271442	1	0	BeFree
Central neuroblastoma	0.000271442	1	0	BeFree
Acute anterior uveitis	0.000271442	1	0	BeFree
Adenomatous polyp of colon	0.000271442	1	0	BeFree
Sleeplessness	0.000271442	1	1	BeFree
Grade 2 Colorectal Adenocarcinoma	0.000271442	1	0	BeFree
Cancer Cell Growth	0.000271442	1	0	BeFree
Glioblastoma Multiforme	0.000271442	1	0	BeFree
Benign Prostatic Hyperplasia	0.000271442	1	0	BeFree
Non-Neoplastic Disorder	0.000271442	1	0	BeFree
Glucocorticoid Receptor Deficiency	0.000271442	1	0	BeFree
Triple-Negative Breast Carcinoma	0.000271442	1	0	BeFree