MGEA5基因详情-基因数据库-基因云馆

MGEA5(meningioma expressed antigen 5 (hyaluronidase)) 转至新版数据库

基因简称(symbol)

MGEA5 [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

MEA5|NCOAT|OGA

基因家族代码(gene_family_id)

[HGNC] [GenScript]

omim代码

604039

entrez码

10724 [Vega]

vega基因码

OTTHUMG00000018939

ensembl基因码

ENSG00000198408 [Ensembl]

基因家族(gene family)

refseq数据库代号

NM_012215

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

10q24.1-q24.3

同源基因名称(alias name)

nuclear cytoplasmic O-GlcNAcase and acetyltransferase

基因名称批准使用时间(date_approved_reserved)

1999-09-09T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

更新时间(date_modified)

2014-11-19T00:00:00Z

ucsc码

uc001ktv.2

ena

AF036144

ccds数据码

CCDS7520|CCDS44471

uniprot数据码

O60502

pubmed代码

9811929|16356930

mgd码

MGI:1932139

rgd码

RGD:621077

生命科学数据库(lsdb)

更新时间(date modified)

2014-11-19T00:00:00Z

cosmic

MGEA5

mirbase

基因曾用简称(prev symbol)

基因曾用名称(prev name)

homeodb

cosmic

MGEA5

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

10q24.1-q24.3

The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008]

[中文简述(自动翻译):] 按O连接的N-乙酰细胞质和细胞核蛋白的动态修改（O-GlcNAc的）添加和删除的丝氨酸和苏氨酸残基被OGT催化（MIM 300255），它增加了O型N-乙酰葡糖胺和MGEA5，糖苷酶，消除O型的GlcNAc修饰（Gao等，2001 [考研11148210]）。[由OMIM，2008年3月供应]

OMIM数据库中对MGEA5基因的介绍 Wikipedia数据库中对MGEA5基因的介绍

MGEA5基因的碱基序列：[NCBI]

MGEA5基因的碱基突变：显示全部snp

rs3180859 rs3740421 rs3808940 rs7918809 rs35402016 rs35960171 rs41291488 rs59433695 rs61874108 rs74153082 rs76288602 rs78585955 rs78638806 rs112906098 rs117626890 rs138146056 rs138234277 rs138801582 rs139086369 rs139988470 rs140196055 rs140996213 rs141255559 rs145620308 rs145620664 rs146002226 rs147941364 rs148256833 rs148937959 rs150751890 rs180890608 rs182284896 rs184052303 rs184505355 rs186044127 rs186220623 rs188358511

rs190562257 rs191832122 rs193246868 rs368578844 rs369682444 rs369777459 rs371467041 rs373237973 rs377213058 rs527429342 rs528297206 rs528349617 rs529170391 rs529675168 rs530472366 rs530745146 rs531996912 rs532300121 rs532769103 rs533456125 rs534066547 rs534659984 rs535273075 rs536724103 rs537230809 rs539294773 rs541392718 rs541437954 rs543681105 rs545400618 rs545488878 rs546569423 rs547208110 rs548231099 rs548280767 rs551230595 rs551318377 rs551911234 rs552307103 rs553410450 rs554781320 rs555710737 rs555919284 rs556517937 rs557355195 rs557890455 rs558171545 rs558289452 rs559974747 rs560968666 rs563424667 rs563787054 rs564784206 rs564823564 rs567532312 rs567816151 rs568553266 rs569199887 rs570882182 rs570975993 rs571882113 rs571969374 rs574272062 rs575801605 rs576231878 rs576578903 rs576716043 rs578044733 rs578070762 rs745554781 rs745924989 rs746006935 rs746744543 rs746977926 rs748597306 rs749515947 rs750357754 rs751468999 rs752423704 rs753164583 rs753225355 rs753452618 rs754417910 rs754715375 rs756978508 rs757278515 rs758138344 rs758248765 rs759809892 rs761094424 rs761198071 rs761485970 rs762077152 rs762317970 rs762550012 rs763271584 rs763826945 rs763882076 rs764632053 rs764993364 rs765320393 rs766008174 rs767220124 rs767894914 rs768107121 rs768803840 rs768930333 rs770093035 rs770437279 rs770707786 rs771507667 rs773572391 rs775198689 rs775506618 rs776056462 rs777666143 rs777715133 rs778422429 rs779073732 rs779616603 rs780117971 rs780989018 rs780989656 rs14591 rs1008013 rs1043250 rs1124714 rs1374472 rs2305191 rs2305192 rs2305193 rs2305194 rs3740422 rs3758557 rs3758558 rs4332454 rs4919595 rs4919596 rs5787445 rs6584456 rs6584457 rs6584458 rs7091701 rs7095274 rs7896302 rs7913120 rs10716391 rs11191116 rs11191117 rs11191118 rs11397528 rs11553297 rs11817066 rs12245261 rs12245394 rs12246547 rs12248493 rs12255828 rs17114193 rs17114200 rs17435911 rs17697840 rs17697908 rs17697930 rs17770568 rs17770716 rs17770756 rs17853930 rs34183320 rs34412824 rs35233825 rs35920682 rs35977547 rs41291486 rs41302699 rs41307050 rs61874099 rs61874100 rs61874101 rs61874102 rs61874103 rs61874104 rs67433227 rs67782181 rs71471214 rs71471215 rs71472586 rs71472587 rs74153081 rs75074756 rs75115325 rs75254166 rs75699610 rs75823291 rs75995707 rs76000708 rs76010966 rs76064381 rs76134290 rs76412912 rs76660176 rs76764775 rs76830660 rs77030441 rs77175639 rs77221258 rs77231996 rs77596024 rs77681343 rs79087249 rs79132044 rs79369262 rs79385712 rs79392311 rs79404906 rs79452940 rs79614990 rs80068326 rs111353160 rs111424948 rs111514173 rs111672513 rs112093104 rs112292834 rs112753952 rs112765692 rs112786272 rs112801840 rs112825978 rs112877672 rs112909241 rs113032515 rs113185413 rs113281291 rs113309891 rs113371301 rs113523285 rs114206659 rs114282663 rs114582558 rs114590101 rs114627918 rs114889137 rs115740327 rs116398696 rs117343627 rs117526247 rs118192071 rs137857944 rs137907187 rs138013957 rs138294945 rs138357684 rs138375392 rs138655144 rs138825353 rs139245365 rs139348196 rs139394167 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rs150089353 rs150281020 rs150603768 rs150606564 rs150657832 rs151008408 rs151060751 rs151130269 rs180731268 rs180744639 rs180760614 rs180863200 rs180884572 rs180911661 rs181189226 rs181216201 rs181620279 rs181667315 rs181907038 rs181917652 rs182105691 rs182117579 rs182348621 rs182385094 rs182466742 rs182611801 rs182618250 rs182628436 rs182935599 rs183001288 rs183071956 rs183188672 rs183321128 rs183473775 rs183588877 rs183598073 rs183616637 rs183789299 rs183822684 rs183944883 rs183980687 rs184054373 rs184186150 rs184192877 rs184490257 rs184674169 rs184831697 rs184834528 rs184999806 rs185032811 rs185046879 rs185129712 rs185189200 rs185193716 rs185279769 rs185624365 rs185744213 rs185792857 rs186059226 rs186084079 rs186230142 rs186465187 rs186565469 rs186689121 rs186699226 rs186815673 rs187032883 rs187036000 rs187050831 rs187186797 rs187189228 rs187202793 rs187436511 rs187570824 rs187579976 rs187619308 rs187779257 rs188095600 rs188146032 rs188302976 rs188370292 rs188520237 rs188658116 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rs530746165 rs530890516 rs531020013 rs531106198 rs531166977 rs531419443 rs531438371 rs531792723 rs531891760 rs531893391 rs531912052 rs532307123 rs532427674 rs532649109 rs532909874 rs532972260 rs533060536 rs533246008 rs533258447 rs533294263 rs533323089 rs533396465 rs533544216 rs533822382 rs533872480 rs534349706 rs534412326 rs534419078 rs534493061 rs534496538 rs534533220 rs534722024 rs534812623 rs534877379 rs534966712 rs535040223 rs535096095 rs535127069 rs535233364 rs535238258 rs535279436 rs535451241 rs535459421 rs535459500 rs535513686 rs535520838 rs535630453 rs535784960 rs535903319 rs535989234 rs535992581 rs536028404 rs536060164 rs536122368 rs536134997 rs536187703 rs536248925 rs536380457 rs536531301 rs536590227 rs536842114 rs536859192 rs537003230 rs537064858 rs537068457 rs537298987 rs537309347 rs537387566 rs537405881 rs537526332 rs537589148 rs537689585 rs537994317 rs538201057 rs538295062 rs538462886 rs538522716 rs538540405 rs538574461 rs538584807 rs538645472 rs538795695 rs538856339 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rs555791087 rs556176829 rs556239230 rs556389386 rs556532937 rs556592273 rs556661383 rs556785384 rs556830228 rs556848935 rs557042990 rs557169174 rs557185834 rs557237974 rs557244712 rs557247676 rs557535453 rs557623916 rs557647504 rs557711770 rs557786082 rs557862344 rs557913765 rs557973172 rs557986391 rs558054991 rs558058517 rs558105083 rs558125670 rs558248567 rs558248646 rs558456426 rs558723237 rs558803700 rs558892207 rs558943288 rs559188024 rs559280715 rs559345016 rs559433920 rs559445910 rs559704805 rs559896616 rs559960009 rs559960113 rs559996030 rs560015461 rs560021937 rs560049893 rs560204317 rs560657275 rs560783908 rs560842116 rs560998421 rs561020389 rs561110197 rs561200901 rs561250693 rs561793514 rs561856384 rs561888461 rs561931633 rs561973529 rs561992007 rs562059796 rs562369554 rs562456218 rs562690497 rs562803867 rs562930869 rs563023164 rs563024083 rs563251395 rs563313124 rs563335112 rs563517967 rs563520864 rs563587543 rs563635964 rs563698756 rs563828326 rs563915931 rs563945360 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rs762785045 rs762802106 rs762805301 rs762927542 rs763036573 rs763076364 rs763173504 rs763239760 rs763371196 rs763547663 rs763720317 rs763880091 rs763897610 rs764058857 rs764077922 rs764425200 rs764550840 rs764621054 rs764632409 rs764632525 rs764728926 rs764805316 rs765037400 rs765040885 rs765200584 rs765200911 rs765386354 rs765445783 rs765615409 rs765620383 rs765666353 rs765732517 rs765840267 rs765894089 rs765962181 rs766002461 rs766114833 rs766282321 rs766354555 rs766548049 rs766592335 rs766698791 rs766703666 rs766740949 rs766750100 rs766751944 rs766936377 rs766978233 rs767161554 rs767197658 rs767235949 rs767416465 rs767428001 rs767599956 rs767732297 rs767895377 rs767895437 rs767900052 rs768048738 rs768094511 rs768122149 rs768126488 rs768248519 rs768357729 rs768491159 rs768493929 rs768631230 rs768763028 rs768930263 rs768946293 rs769114035 rs769115626 rs769137334 rs769271695 rs769502521 rs769522659 rs769551167 rs769682602 rs769909928 rs769939385 rs770015307 rs770034610 rs770070654 rs770327656 rs770367115 rs770420725 rs770454446 rs770560497 rs770657574 rs770816843 rs770968611 rs771145502 rs771152954 rs771160479 rs771177838 rs771586698 rs771633700 rs771711788 rs771731487 rs771852195 rs771883274 rs772074193 rs772105395 rs772205095 rs772318111 rs772342126 rs772594041 rs772613837 rs772865775 rs772903834 rs773173923 rs773254699 rs773302723 rs773311470 rs773412983 rs773468833 rs773470882 rs773990456 rs774027994 rs774043173 rs774059958 rs774250791 rs774323229 rs774335661 rs774361959 rs774884277 rs775017700 rs775043474 rs775227848 rs775320487 rs775392805 rs775450564 rs775460845 rs775494887 rs775564541 rs775650244 rs776010466 rs776108763 rs776110915 rs776160908 rs776206078 rs776239055 rs776598899 rs776714346 rs776757939 rs776820028 rs776890029 rs777057529 rs777328265 rs777365221 rs777555675 rs777629575 rs777717183 rs777748497 rs777754099 rs777830908 rs777860644 rs778031678 rs778191444 rs778247719 rs778288942 rs778330794 rs778383941 rs778421814 rs778593821 rs778698318 rs778702709 rs778753328 rs778965388 rs778973373 rs779216262 rs779342978 rs779381439 rs779408774 rs779473170 rs779541881 rs779922905 rs779933781 rs780086072 rs780268719 rs780367936 rs780465135 rs780477090 rs780513990 rs780567376 rs780567491 rs780687387 rs780749739 rs780777078 rs780936049 rs780980104 rs781139518 rs781160110 rs781163347 rs781278422 rs781280951 rs781327907 rs781423197 rs781524499 rs781656502 rs781695647

MGEA5基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

CTAGCAGGAGAGTTCCAGC

60

AGGTAGGAGTCAGTGGAGG

60

ACTGAAGGCTAATGGCTCC

60

CACATCCTTTGGAAATCCTTCC

60

GTAACTGACCCAAGTGTGG

58

GAGCCATTAGCCTTCAGTG

58

CTCACCTGGATTGGATATCAC

58

AACTGAGAAACCTGGTCCA

59

AGTAACTGACCCAAGTGTGG

60

GAGCCATTAGCCTTCAGTG

58

CACTGAAGGCTAATGGCTC

58

ACATCCTTTGGAAATCCTTCC

58

GGAAGCTGAGCAACTTATGAC

59

CAATCCAGGTGAGATCGCA

60

CTAGCAGGAGAGTTCCAGC

60

GAGGTAGGAGTCAGTGGAG

58

CTCACCTGGATTGGATATCAC

58

AAACTGAGAAACCTGGTCC

57

CTAGCAGGAGAGTTCCAGC

60

GTAGGAGTCAGTGGAGGTG

59

尚未收录相关数据

MGEA5基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

MGEA5基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0004415

O60502(UniProtKB)

TAS

GO:0005634

O60502(UniProtKB)

IEA

GO:0005829

O60502(UniProtKB)

IDA

GO:0006044

O60502(UniProtKB)

IDA

GO:0006516

O60502(UniProtKB)

TAS

GO:0006517

O60502(UniProtKB)

IDA

GO:0016020

O60502(UniProtKB)

IDA

GO:0016231

O60502(UniProtKB)

IDA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控MGEA5基因的相关microRNA：

hsa-miR-98 hsa-miR-17 hsa-miR-30c

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Reperfusion Injury	0.08	1	0	RGD
Tay-Sachs Disease	0.016829396	62	0	BeFree
Sandhoff Disease	0.008143256	30	0	BeFree
Diabetes Mellitus, Non-Insulin-Dependent	0.005905708	3	0	BeFree_GAD_LHGDN
Lysosomal Storage Diseases	0.002985861	11	0	BeFree
Gangliosidoses, GM2	0.002171535	8	0	BeFree
Motor Neuron Disease	0.001357209	5	0	BeFree
Neurodegenerative Disorders	0.001357209	5	0	BeFree
Myxoinflammatory fibroblastic sarcoma	0.001085767	4	0	BeFree
Diabetes	0.000814326	3	0	BeFree
Diabetes Mellitus	0.000814326	3	0	BeFree
Gangliosidoses	0.000814326	3	0	BeFree
Alzheimer's Disease	0.000542884	2	0	BeFree
Gaucher Disease	0.000542884	2	0	BeFree
Hypertensive disease	0.000542884	2	0	BeFree
Kidney Diseases	0.000542884	2	0	BeFree
Obesity	0.000542884	2	0	BeFree
Infantile Sandhoff Disease	0.000542884	2	0	BeFree
Juvenile Sandhoff Disease	0.000542884	2	0	BeFree
Pleomorphic hyalinizing angiectatic tumor	0.000542884	2	0	BeFree
Aortic Valve Stenosis	0.000271442	1	0	BeFree
Arteriosclerosis	0.000271442	1	0	BeFree
Atherosclerosis	0.000271442	1	0	BeFree
Malignant neoplasm of breast	0.000271442	1	0	BeFree
Colorectal Carcinoma	0.000271442	1	0	BeFree
Encephalitis	0.000271442	1	0	BeFree
Glioblastoma	0.000271442	1	0	BeFree
Heart failure	0.000271442	1	0	BeFree
Congestive heart failure	0.000271442	1	0	BeFree
Type II Mucolipidosis	0.000271442	1	0	BeFree
Meningioma	0.000271442	1	0	BeFree
Mucopolysaccharidoses	0.000271442	1	0	BeFree
Myocardial Infarction	0.000271442	1	0	BeFree
Panic Disorder	0.000271442	1	0	BeFree
Parkinson Disease	0.000271442	1	0	BeFree
Pseudo-Hurler Polydystrophy	0.000271442	1	0	BeFree
Sphingolipidoses	0.000271442	1	0	BeFree
Mucopolysaccharidosis Type IIIA	0.000271442	1	0	BeFree
Memory impairment	0.000271442	1	0	BeFree
Tay-Sachs Disease, AB Variant	0.000271442	1	0	BeFree
Impaired glucose tolerance	0.000271442	1	0	BeFree
Senile Plaques	0.000271442	1	0	BeFree
Impaired cognition	0.000271442	1	0	BeFree
Malignant neoplasm of prostate	0.000271442	1	0	BeFree
Prostate carcinoma	0.000271442	1	0	BeFree
Breast Carcinoma	0.000271442	1	0	BeFree
Secondary malignant neoplasm of lymph node	0.000271442	1	0	BeFree
Microalbuminuria	0.000271442	1	0	BeFree
Anaphylaxis (non medication)	0.000271442	1	0	BeFree
Diabetic Cardiomyopathies	0.000271442	1	0	BeFree
Post MI	0.000271442	1	0	BeFree
Renal ischaemia	0.000271442	1	0	BeFree
Colorectal cancer metastatic	0.000271442	1	0	BeFree
Sarcoma	0.000271442	1	0	BeFree
Colorectal Cancer	0.000271442	1	0	BeFree
Meningioma, benign, no ICD-O subtype	0.000271442	1	0	BeFree
Hexosaminidase alpha-Subunit Deficiency (Variant B)	0.000271442	1	0	BeFree
PANIC DISORDER 1	0.000271442	1	0	BeFree
Plaque, Amyloid	0.000271442	1	0	BeFree