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This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  这个基因编码麦芽糖酶 - 葡糖淀粉酶,它是起着淀粉消化的最后步骤一角色的刷状缘膜酶。的蛋白质具有相同的那些蔗糖酶 - 异麦芽糖酶的两个催化位点,但该蛋白质是只有59%的同源性。两者都是糖基水解酶家族31,其具有多种底物特异性的成员。 [由RefSeq的,2008年7月提供]
MGAM基因(以及对应的蛋白质)的细胞分布位置:
MGAM基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Malignant neoplasm of breast | 0.000814326 | 3 | 0 | BeFree |
Breast Carcinoma | 0.000814326 | 3 | 0 | BeFree |
Squamous cell carcinoma | 0.000271442 | 1 | 0 | BeFree |
Chronic Lymphocytic Leukemia | 0.000271442 | 1 | 0 | BeFree |
Leukemia, Lymphocytic, Acute, L1 | 0.000271442 | 1 | 0 | BeFree |
Small cell carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
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