MARCKS(myristoylated alanine-rich protein kinase C substrate) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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6q21
基因染色体位置图

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白是蛋白激酶C的衬底它被定位于质膜,是一种肌动蛋白丝的交联蛋白质。磷酸化的蛋白激酶C或结合钙调蛋白抑制其关联与肌动蛋白和与质膜,导致其在细胞质中的存在。该蛋白被认为是参与细胞运动,吞噬作用,膜运输和有丝分裂发生。 [由RefSeq的,2008年7月提供]

MARCKS基因的碱基序列:[NCBI]
MARCKS基因的碱基突变:           显示全部snp
rs10585       rs12223       rs12307       rs352082       rs352083       rs352084       rs352085       rs352090       rs476354       rs660645       rs1049561       rs3734457       rs3734458       rs3832411       rs3837006       rs7769769       rs9387180       rs28558559       rs34827890       rs35390470       rs45448797       rs45457891       rs45457993       rs45460602       rs45469794       rs45471496       rs45477193       rs45495999       rs45496094       rs45516098       rs45522234       rs45528938       rs45535333       rs45537138       rs45564039       rs45568231       rs45584031      
rs45618440       rs45622343       rs45622441       rs56265018       rs56281739       rs59932241       rs60141787       rs73768567       rs75033310       rs75690058       rs78329275       rs78826488       rs79053472       rs79755478       rs111745301       rs112051674       rs113213077       rs113437665       rs114936806       rs115868171       rs116002365       rs138142128       rs138404099       rs139925404       rs140343257       rs141043005       rs141491332       rs142639861       rs144135156       rs144738162       rs145409534       rs145476378       rs146698195       rs147240197       rs147289301       rs149350734       rs149796810       rs149845826       rs181436457       rs182156128       rs182598859       rs182811517       rs182919904       rs183996000       rs184093645       rs185537201       rs185776191       rs186191751       rs187145968       rs188595922       rs189092612       rs189101937       rs189848280       rs190105919       rs190766195       rs191575968       rs191924420       rs192188121       rs193287289       rs200886882       rs201951863       rs367945569       rs368150133       rs369178638       rs371975808       rs374005986       rs374780311       rs375785979       rs397718021       rs397897543       rs397897544       rs397897545       rs527368616       rs528362948       rs528567145       rs528918868       rs529186587       rs529354853       rs530132101       rs530574258       rs530708634       rs530884087       rs531328373       rs531749151       rs531808007       rs532832793       rs534223513       rs534641175       rs535195321       rs536749561       rs537535746       rs537880962       rs538144356       rs538419580       rs538684852       rs538925937       rs539350596       rs540067570       rs540089435       rs540393844       rs540656597       rs541240412       rs541647979       rs542287099       rs542322096       rs542546280       rs543117743       rs544168450       rs544523902       rs544963217       rs545174094       rs545631620       rs545855557       rs546028728       rs546620703       rs547258665       rs547521790       rs547617460       rs548024128       rs548026791       rs548079843       rs548095601       rs548583110       rs548717045       rs549357416       rs549939916       rs550574213       rs551198351       rs551873272       rs552065739       rs552654189       rs552654528       rs552675975       rs552989838       rs553285049       rs553740716       rs554121224       rs554134745       rs555054844       rs555593715       rs556127881       rs556390233       rs557713866       rs558330638       rs558511712       rs559067544       rs559763616       rs560022535       rs560614131       rs560738308       rs562238445       rs562350900       rs562668162       rs563674198       rs564436372       rs564637981       rs565272007       rs565541644       rs566068601       rs566081782       rs566530618       rs566957402       rs567025772       rs567655761       rs568185965       rs569008384       rs569204326       rs569321680       rs569514603       rs569588122       rs570200803       rs570827525       rs571317171       rs571427141       rs571580950       rs572021544       rs572480034       rs573892769       rs573964101       rs574032616       rs574127019       rs575098973       rs575917860       rs576844500       rs577696892       rs577760224       rs577849143       rs745339668       rs745514148       rs745621515       rs745705724       rs745912162       rs746357704       rs746484006       rs746927650       rs747021027       rs747129556       rs747289993       rs747559001       rs747922228       rs748038159       rs748324461       rs748388877       rs748486045       rs748952492       rs749287169       rs749538693       rs750021172       rs750080973       rs750382884       rs750403322       rs750643113       rs750659608       rs751349905       rs751535463       rs751968851       rs751997091       rs752367758       rs752535414       rs753251410       rs753655112       rs753805489       rs753998792       rs754266006       rs754321790       rs754671406       rs755046254       rs755557718       rs755609248       rs756479458       rs757528973       rs757591352       rs758201982       rs758347518       rs758470167       rs758498243       rs758674884       rs759602044       rs759844108       rs760307753       rs760347613       rs760406520       rs761352233       rs761560822       rs761626066       rs761907101       rs762501200       rs762954558       rs763054918       rs763294989       rs763437592       rs763618371       rs763643494       rs763667695       rs763885245       rs764652897       rs764826680       rs764845067       rs765246683       rs766186044       rs766256270       rs766347690       rs766585915       rs767114412       rs767199531       rs767266045       rs767348295       rs767707706       rs767879079       rs768078831       rs768430961       rs768621645       rs768898782       rs769044278       rs769082276       rs769487523       rs769611262       rs769625706       rs769960834       rs770341869       rs770489201       rs770661278       rs770687898       rs771019720       rs771467511       rs772018612       rs772083976       rs772417409       rs772613203       rs772900155       rs773029468       rs773224073       rs773703695       rs774350655       rs774461693       rs774868136       rs775342784       rs775757329       rs775771344       rs775883251       rs776084029       rs776099567       rs776460741       rs777148327       rs777508406       rs777714355       rs777809788       rs777877929       rs777963306       rs778347674       rs778576064       rs778823857       rs778938816       rs778948419       rs779026873       rs779508920       rs779600997       rs779621026       rs780063911       rs780249753       rs780371708       rs781128418       rs781382338       rs781507807       rs781744930       rs869276442      

MARCKS基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AACAAGAAGGAGGCTGGAG
59
TTTCTCCTCCACCTTGCTG
60
AGAACAAGAAGGAGGCTGG
59
TTTCTCCTCCACCTTGCTG
60
GAACAAGAAGGAGGCTGGA
59
TTTCTCCTCCACCTTGCTG
60
AGAACAAGAAGGAGGCTGG
59
TTTCTCCTCCACCTTGCTG
60
AACAAGAAGGAGGCTGGAG
59
TTTCTCCTCCACCTTGCTG
60
GAACAAGAAGGAGGCTGGA
59
TTTCTCCTCCACCTTGCTG
60
      尚未收录相关数据

MARCKS基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

MARCKS基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0005516
A0A087WZH7(UniProtKB)
IEA
GO:0001520
P29966(UniProtKB)
IEA
GO:0001786
P29966(UniProtKB)
IEA
GO:0003229
P29966(UniProtKB)
IEA
GO:0005080
P29966(UniProtKB)
IEA
GO:0005516
P29966(UniProtKB)
IEA
GO:0005764
P29966(UniProtKB)
IEA
GO:0005813
P29966(UniProtKB)
IEA
GO:0005829
P29966(UniProtKB)
IEA
GO:0005874
P29966(UniProtKB)
IEA
GO:0005886
P29966(UniProtKB)
TAS
GO:0005925
P29966(UniProtKB)
IDA
GO:0005938
P29966(UniProtKB)
IEA
GO:0006886
P29966(UniProtKB)
IEA
GO:0007015
P29966(UniProtKB)
IEA
GO:0007420
P29966(UniProtKB)
IEA
GO:0015629
P29966(UniProtKB)
TAS
GO:0030426
P29966(UniProtKB)
IEA
GO:0031584
P29966(UniProtKB)
IEA
GO:0031589
P29966(UniProtKB)
IEA
GO:0032059
P29966(UniProtKB)
IEA
GO:0033391
P29966(UniProtKB)
IEA
GO:0042585
P29966(UniProtKB)
IEA
GO:0043197
P29966(UniProtKB)
IEA
GO:0043679
P29966(UniProtKB)
IEA
GO:0044307
P29966(UniProtKB)
IEA
GO:0050796
P29966(UniProtKB)
TAS
GO:0051015
P29966(UniProtKB)
TAS
GO:0061003
P29966(UniProtKB)
IEA
GO:0070062
P29966(UniProtKB)
IDA
GO:0070062
P29966(UniProtKB)
IDA
GO:0070062
P29966(UniProtKB)
IDA
GO:1900020
P29966(UniProtKB)
IEA
GO:2001275
P29966(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控MARCKS基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Rheumatoid Arthritis 0.12 1 0 CTD_human
Adenoid Cystic Carcinoma 0.12 1 0 CTD_human
IGA Glomerulonephritis 0.12 1 0 CTD_human
Salivary Gland Neoplasms 0.12 1 0 CTD_human
Seizures 0.08 1 0 RGD
Hyperplasia 0.00272435 1 0 LHGDN
Neuroblastoma 0.001628651 6 0 BeFree
Central neuroblastoma 0.001628651 6 0 BeFree
Glioma 0.001085767 4 0 BeFree
Adenocarcinoma 0.000814326 3 0 BeFree
Colorectal Carcinoma 0.000814326 3 0 BeFree
Carcinogenesis 0.000814326 3 0 BeFree
Neoplasm Metastasis 0.000542884 2 0 BeFree
Malignant neoplasm of lung 0.000542884 2 0 BeFree
Carcinoma of lung 0.000542884 2 0 BeFree
Colon Carcinoma 0.000542884 2 0 BeFree
Colorectal Cancer 0.000542884 2 0 BeFree
Liver carcinoma 0.000542884 2 0 BeFree
Alzheimer's Disease 0.000271442 1 0 BeFree
Asthma 0.000271442 1 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Malignant tumor of colon 0.000271442 1 0 BeFree
Squamous cell carcinoma 0.000271442 1 0 BeFree
Choriocarcinoma 0.000271442 1 0 BeFree
Cystic Fibrosis 0.000271442 1 0 BeFree
Mental Depression 0.000271442 1 0 BeFree
Depressive disorder 0.000271442 1 0 BeFree
Hepatitis 0.000271442 1 0 BeFree
Hepatitis A 0.000271442 1 0 BeFree
Hepatitis, Chronic 0.000271442 1 0 BeFree
HIV Infections 0.000271442 1 0 BeFree
Acute lymphocytic leukemia 0.000271442 1 0 BeFree
Liver Cirrhosis 0.000271442 1 0 BeFree
Lung Neoplasms 0.000271442 1 0 BeFree
melanoma 0.000271442 1 0 BeFree
Meningomyelocele 0.000271442 1 0 BeFree
Multiple Myeloma 0.000271442 1 0 BeFree
Cholangiocarcinoma 0.000271442 1 0 BeFree
Liver and Intrahepatic Biliary Tract Carcinoma 0.000271442 1 0 BeFree
Malignant neoplasm of liver 0.000271442 1 0 BeFree
Metabolic Syndrome X 0.000271442 1 1 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Biliary Tract Cancer 0.000271442 1 0 BeFree
Mammary Neoplasms 0.000271442 1 0 BeFree
Xenograft Model 0.000271442 1 0 BeFree
Glioblastoma Multiforme 0.000271442 1 0 BeFree
Cirrhosis 0.000271442 1 0 BeFree
Precursor Cell Lymphoblastic Leukemia Lymphoma 0.000271442 1 0 BeFree
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