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This gene encodes a serine/threonine protein kinase that forms a component of protein kinase-mediated signal transduction cascades. The encoded kinase participates in the regulation of vascular endothelial growth factor (VEGF) expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
[中文简述(自动翻译):]  这个基因编码形成蛋白激酶介导的信号转导级联的成分的丝氨酸/苏氨酸蛋白激酶。该编码激酶参与血管内皮生长因子(VEGF)表达的调节。选择性剪接结果在多个抄本变形。 [由RefSeq的,2014年7月提供]
MAP3K6基因(以及对应的蛋白质)的细胞分布位置:
MAP3K6基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Hereditary Diffuse Gastric Cancer | 0.12 | 0 | 0 | ORPHANET |
| Huntington Disease | 0.002367032 | 1 | 0 | GAD |
| Malignant neoplasm of stomach | 0.000271442 | 1 | 0 | BeFree |
| Carcinogenesis | 0.000271442 | 1 | 0 | BeFree |
| Stomach Carcinoma | 0.000271442 | 1 | 0 | BeFree |
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