MAGEB2基因详情-基因数据库-基因云馆

MAGEB2(melanoma antigen family B2) 转至新版数据库

基因简称(symbol)

MAGEB2 [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

DAM6|MAGE-XP-2|MGC26438|CT3.2

基因家族代码(gene_family_id)

[HGNC] [GenScript]

omim代码

300098

entrez码

4113 [Vega]

vega基因码

OTTHUMG00000021319

ensembl基因码

ENSG00000099399 [Ensembl]

基因家族(gene family)

refseq数据库代号

NM_002364

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

Xp21.3

同源基因名称(alias name)

DSS/AHC critical interval MAGE superfamily 6|melanoma-associated antigen B2|cancer/testis antigen family 3, member 2

基因名称批准使用时间(date_approved_reserved)

1997-08-15T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

2015-02-06T00:00:00Z

更新时间(date_modified)

2015-02-06T00:00:00Z

ucsc码

uc004dbz.3

ena

AF015766

ccds数据码

CCDS14219

uniprot数据码

O15479

pubmed代码

9441743

mgd码

MGI:2148568

rgd码

RGD:1560904

生命科学数据库(lsdb)

Mental Retardation database|http://grenada.lumc.nl/LOVD2/MR/home.php?select_db=MAGEB2

更新时间(date modified)

2015-02-06T00:00:00Z

cosmic

MAGEB2

mirbase

基因曾用简称(prev symbol)

基因曾用名称(prev name)

homeodb

cosmic

MAGEB2

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

Xp21.3

This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):] 此基因是MAGEB基因家族的一个成员。该家族的成员具有位于在最后的外显子的完整编码序列和编码的蛋白质显示50?68％的序列同一性的对方。所述启动子和所述MAGEB基因的第一外显子显示出相当的变异，这表明该基因家族的存在使在不同的转录控制待表达相同的功能。该基因在DSS（剂量敏感的性反转）临界区的本地化。它是在睾丸和胎盘中表达，并在各种组织学类型的肿瘤的一个显著分数。该MAGEB基因聚集于染色体Xp22-P21。 [由RefSeq的，2008年7月提供]

OMIM数据库中对MAGEB2基因的介绍 Wikipedia数据库中对MAGEB2基因的介绍

MAGEB2基因的碱基序列：[NCBI]

MAGEB2基因的碱基突变：显示全部snp

rs781689631 rs781480206 rs781070614 rs780694497 rs780983841 rs780526167 rs780267669 rs780419769 rs780072766 rs779542719 rs779723991 rs779986988 rs779059004 rs779310270 rs778798000 rs778488431 rs778590723 rs778411044 rs778038626 rs777645955 rs777755383 rs777415745 rs777521213 rs777596230 rs777166552 rs777365702 rs776998052 rs777044216 rs776599379 rs776963214 rs776596378 rs776157928 rs775590244 rs776050887 rs775011252 rs775111636 rs775430700

rs774317963 rs774884656 rs774033552 rs773794633 rs773897216 rs773793515 rs773736404 rs773293973 rs773023961 rs773239129 rs773013541 rs772974183 rs772469237 rs772656322 rs771999721 rs772060099 rs771735549 rs771758637 rs771996185 rs771249184 rs771396236 rs771231268 rs771089577 rs771206196 rs770996632 rs770873217 rs770866259 rs769925797 rs770379532 rs770813074 rs769444637 rs769180547 rs768671683 rs769156703 rs768306363 rs768495623 rs768252567 rs768025185 rs768249275 rs767023113 rs767747644 rs767906444 rs766710849 rs766889118 rs766708296 rs766418758 rs766464904 rs766411756 rs765958802 rs765211660 rs765460965 rs765467245 rs764914099 rs764521778 rs764868986 rs764422051 rs764267504 rs764189196 rs763955400 rs763345977 rs763745250 rs763002185 rs763090072 rs762869845 rs762392461 rs762536785 rs761837486 rs761964672 rs761655780 rs761165706 rs761050183 rs760996564 rs761032700 rs760819328 rs760530134 rs760208597 rs760131792 rs759980804 rs759971709 rs759589923 rs759794188 rs759205287 rs759337831 rs759463095 rs759037143 rs759031616 rs758812052 rs758936510 rs758611372 rs758339197 rs757914942 rs757946591 rs757587393 rs757436089 rs757368435 rs756877832 rs757043954 rs756812571 rs756700712 rs756683025 rs756246520 rs756299317 rs756232146 rs756066149 rs755696118 rs755960252 rs755372967 rs755263954 rs755308637 rs755130579 rs755077861 rs754781859 rs754734083 rs754303672 rs754207788 rs754118107 rs753991418 rs754029924 rs753012331 rs752960894 rs752969442 rs752688181 rs752680338 rs752497478 rs752312475 rs752059348 rs752297804 rs751938258 rs751768980 rs751488182 rs751527124 rs751476061 rs750467118 rs750718375 rs751176441 rs750240402 rs750344520 rs749778121 rs749754445 rs749164974 rs749077535 rs748819651 rs748764119 rs748798560 rs748531899 rs748333127 rs747893990 rs748255078 rs747754701 rs747474804 rs747604980 rs747391833 rs747224013 rs747338040 rs747129353 rs746176783 rs747116536 rs746102460 rs746022879 rs745779246 rs745960048 rs745727318 rs571426281 rs553308022 rs542465117 rs538851972 rs377141601 rs377566466 rs376868079 rs376780034 rs376379710 rs376713401 rs375117732 rs375229915 rs374368116 rs374398423 rs374833665 rs373920316 rs374280154 rs371294125 rs373793135 rs371044784 rs371023695 rs370067105 rs370758512 rs369826731 rs370019799 rs368971229 rs369559506 rs368665231 rs367729095 rs368622211 rs202101229 rs201970533 rs200872475 rs200649828 rs200351837 rs199746320 rs199666309 rs193132352 rs192753832 rs192601539 rs192488971 rs191526571 rs191402994 rs191043575 rs190886045 rs190638120 rs189871428 rs189402141 rs189110298 rs188984902 rs188831146 rs188441064 rs187749937 rs187670785 rs187431334 rs187380814 rs186554168 rs185983689 rs184949243 rs184927954 rs184603435 rs184471774 rs183769853 rs183434005 rs183272477 rs182954863 rs182855821 rs182815759 rs182034633 rs181120801 rs180835792 rs151181148 rs150466266 rs150250737 rs149932758 rs149245405 rs148939834 rs148646403 rs148432603 rs148428641 rs147843292 rs147559118 rs147546492 rs147433394 rs146783301 rs147147385 rs146480900 rs145657384 rs145330928 rs145085171 rs144472411 rs145075830 rs143715628 rs143404099 rs142602767 rs143298503 rs141924015 rs141884445 rs141049685 rs140291899 rs139938143 rs139581506 rs139272287 rs139471308 rs139121250 rs138995274 rs138365238 rs113375709 rs113294066 rs112528227 rs112588734 rs77669285 rs78970058 rs75261012 rs74852235 rs73460367 rs45513291 rs12837022 rs12011617 rs12011567 rs12011566 rs12009082 rs11798106 rs11797594 rs11095177 rs7878409 rs7057740 rs6628517 rs7056939 rs6526962 rs5973792 rs5972091 rs5972090 rs5901945 rs2529541 rs2238924 rs2238923 rs2238922 rs2238920 rs2074793 rs1974548 rs1894386 rs1053918 rs714793

MAGEB2基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

TGAATTCTCAGGACTGGTCG

60

GAGCTTACTCTTCTGACCAC

58

GGTGAATTCTCAGGACTGG

58

GCTTACTCTTCTGACCACG

58

GGTGAATTCTCAGGACTGG

58

GCTTACTCTTCTGACCACGA

60

尚未收录相关数据

MAGEB2基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

MAGEB2基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0005515

O15479(UniProtKB)

IPI

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控MAGEB2基因的相关microRNA：

hsa-miR-98 hsa-miR-193b

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
melanoma	0.002995792	2	0	BeFree_LHGDN
Renal Cell Carcinoma	0.000271442	1	0	BeFree
Lupus Erythematosus, Systemic	0.000271442	1	0	BeFree
Squamous cell carcinoma of the head and neck	0.000271442	1	0	BeFree