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This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011]
[中文简述(自动翻译):]  该基因编码的LSM家族RNA结合蛋白中的一员。 LSM蛋白形成特异性结合U6 snRNA启动的3‘-末端的寡(U)道,并且可以通过介导U4 / U6核蛋白的形成起到前mRNA剪接作用稳定异聚。该基因的假基因都位于[由RefSeq的,2011年11月提供]染色体6和19的短臂
LSM2基因(以及对应的蛋白质)的细胞分布位置:
LSM2基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Lupus Erythematosus, Systemic | 0.004810009 | 10 | 0 | BeFree_GAD |
Spinal Muscular Atrophy | 0.003800186 | 14 | 0 | BeFree |
Malignant neoplasm of breast | 0.002367032 | 1 | 0 | GAD |
Mixed Connective Tissue Disease | 0.001357209 | 5 | 0 | BeFree |
Retinitis Pigmentosa | 0.000814326 | 3 | 0 | BeFree |
Amyotrophic Lateral Sclerosis | 0.000542884 | 2 | 0 | BeFree |
Autoimmune Diseases | 0.000271442 | 1 | 0 | BeFree |
Connective Tissue Diseases | 0.000271442 | 1 | 0 | BeFree |
Down Syndrome | 0.000271442 | 1 | 0 | BeFree |
Herpes Simplex Infections | 0.000271442 | 1 | 0 | BeFree |
HIV Infections | 0.000271442 | 1 | 0 | BeFree |
Poliomyelitis | 0.000271442 | 1 | 0 | BeFree |
Motor Neuron Disease | 0.000271442 | 1 | 0 | BeFree |
Miller Dieker syndrome | 0.000271442 | 1 | 0 | BeFree |
Carcinogenesis | 0.000271442 | 1 | 0 | BeFree |
Myoclonic Epilepsies, Progressive | 0.000271442 | 1 | 0 | BeFree |
Autoimmune Lymphoproliferative Syndrome | 0.000271442 | 1 | 0 | BeFree |
MICROCEPHALIC OSTEODYSPLASTIC PRIMORDIAL DWARFISM, TYPE I | 0.000271442 | 1 | 0 | BeFree |
Parvovirus B19 (disease) | 0.000271442 | 1 | 0 | BeFree |
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