更多...
收起
This gene encodes gastric lipase, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. It is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
[中文简述(自动翻译):]  这个基因编码胃脂肪酶,参与膳食甘油三酯在胃肠道中的消化酶,以及负责人发生脂肪的消化过程的30%。它是由胃粘膜主细胞在胃的胃底粘膜分泌,和它的酸性pH条件下水解甘油三酸酯的酯键。该基因是一个保守的基因家族发挥中性脂质代谢不同作用的脂肪酶的成员。已发现该基因编码不同亚型的几个抄本变形。 [由RefSeq的,2010年11月提供]
LIPF基因(以及对应的蛋白质)的细胞分布位置:
LIPF基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Schizophrenia | 0.002367032 | 1 | 0 | GAD |
| Cholesterol Ester Storage Disease | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of breast | 0.000271442 | 1 | 0 | BeFree |
| Wolman Disease | 0.000271442 | 1 | 0 | BeFree |
| Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
忘记密码? 点击找回密码.
扫一扫右方二维码,关注微信订阅号,实时查看信息,关注医学生物学动态。